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Coa.ing powder beds with liquids a.d foa.s ba.ed on viscous formula.ions using a.twin screw mixer:a.continuous process study

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Pa.ticuology 2024年第10期93卷 364-376页

作者： Moha.ed S.Ma.ga.Dimitrios Kontzia.pa.is Musta.a.al-Ma.da. Sea. Clifford Sera.im Ba.alis Da.id W.York School of Chemical a.d Process Engineering Faculty of Engineering and Physical SciencesUniversity of LeedsLeedsLS29JTUK School of Mecha.ical Engineering Faculty of Engineering and Physical SciencesUniversity of LeedsLeedsLS29JTUK School of Science a.d Engineering University of DundeeDD14HNDundeeScotlandUK Dundee Interna.ional Institute of Central South University Tongzipo RoadCentral South UniversityChangshaHunan410013China Depa.tment of Chemical Engineering School of EngineeringUniversity of NewcastleNewcastleNE17RUUK School of Chemical Engineering University of BirminghamBirminghamB152TTUK Depa.tment of Chemical Engineering Faculty of EngineeringUniversity of NottinghamNG72RDUK

Coa.ing with viscous formula.ions ha. been essential in numerous industries a. it ca. be a.mea.s for providing functionaliza.ion, a.ditional properties, a. well a. other benefits. However, there ha.e been sca.ce studies tha. ha.e investiga.ed a.d proposed methodologies in litera.ure. Continuous coa.ing of powders with viscous liquids poses a. a.promising technology, which ha. been mentioned in some studies, but ha. not yet been thoroughly investiga.ed. This pa.er employs the use of ima.e processing a.d a.alysis, in combina.ion with sta.istical a.alysis of pa.ticles to evalua.e the effectiveness of foa.s a.d liquids a. a.mea.s of coa.ing powder beds. Two different sizes of twin screw mixers tha. a.e working in continuous opera.ion a.e employed, a.d a.new continuous foa.ing device is fa.rica.ed a.d used for the experiments of coa.ing. The effect of ma.erials a.d process pa.a.eters (a. for exa.ple rota.ional speed, a.d flowra.e) on the quality of coa.ing a.e investiga.ed. Ima.e a.alysis is used to a.sess the coa.ing quality. The results clea.ly showca.e the potential of using twin screw mixers for coa.ing purposes a.d not only for mixing. The hypothesis tha. using la.ge bubble foa.s to improve the coa.ing of viscous liquids on pa.ticles is proven correct, a. they provide higher quality coa.ings compa.ed to their equivalent liquids, when used in the twin screw mixer. Surprisingly, using a.la.ger scale twin screw mixer, does not show a.substa.tial effect on the mixing, rega.ding quality, however there is still a.requirement for mix optimiza.ion for a.hieving scale-up of this process. These results provide a.new pa.hwa. for coa.ing powders with viscous formula.ions in industrial a.plica.ions, requiring less energy a.d effort in this process, a.d ca. pa.e the wa. towa.ds introducing more susta.na.le industrial methodologies for coa.ing.

关键词： Powder coa.ing Continuous processing Viscous liquid Foa. Ima.e a.alysis Positron emission pa.ticle tra.ing(PEPT)

Bullous Pemphigoid Induced by Doxycycline: Ca.e Report a.d Litera.ure Review

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Ca.e Reports in Clinical Medicine 2024年第5期13卷 187-192页

作者： Mishal al Meba.a.h Ra.a. alda.ish Soha.l a. Butt a.dulra.ma. Sa.d alja.ha. Derma.ology Depa.tment Imam Abdulrahman Bin Faisal University-National Guard Hospital Dammam Saudi Arabia Derma.ology Depa.tment Al Rass General Hospital Al-Qassim Saudi Arabia Pa.hology Depa.tment Dammam Regional Laboratory & Blood Bank MOH Dammam Saudi Arabia Clinical Documenta.ion Improvement (CDI) Dammam Health Network Dammam Saudi Arabia

Bullous pemphigoid (BP) is the most prevalent a.toimmune sub-epidermal blistering disea.e tha. a.fects ma.nly the elderly a.d could lea. to serious morbidity. It ha. numerous risk fa.tors a.d triggers, including a. a.ing popula.ion with several comorbidities a.d drug exposure. In the published pa.er, we reported a.ca.e a.out a.32 yea.s old male pa.ient with unknown medical conditions who presented with erythema.ous pa.ches a.d pla.ues on the scalp, fa.e, a.d trunk with sca.tered blisters two weeks a.ter initia.ing doxycycline trea.ment for folliculitis. The exa.t pa.hogenesis of the drug-rea.tion in drug- a.socia.ed bullous pemphigoid (Da.P) rema.ns controversial. In conclusion, it is crucial for clinicia.s to be a.a.e of Da.P when prescribing doxycycline. The purpose of this ca.e report is to ra.se a.a.eness of the possible a.socia.ion between bullous pemphigoid a.d doxycycline.

关键词： Bullous Pemphigoid Doxycycline Drug-a.socia.ed Bullous Pemphigoid

Improved Dwa.f Mongoose Optimiza.ion algorithm for Fea.ure Selection:a.plica.ion in Softwa.e Fa.lt Prediction Da.a.ets

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Journal of Bionic Engineering 2024年第4期21卷 2000-2033页

作者： a.dela.iz I.Ha.mouri Moha.med a.a.a.alla. Malik Sh.Bra.k Moha.med a.mi al-Beta. Ma.di Beseiso Depa.tment of Computer Science Al-Balqa Applied UniversityAl-Salt19117Jordan Depa.tment of Scientific Resea.ch a.d Gra.ua.e Studies University of Prince Mugrin42241MedinaSaudi Arabia Depa.tment of Computer Science Al-Aqsa UniversityGaza4051Palestine a.tificial Intelligence Resea.ch Center(a.RC) Ajman UniversityAjmanUnited Arab Emirates Depa.tment of Informa.ion Technology Al-Huson University CollegeAl-Balqa Applied UniversityAl-HusonIrbid21110Jordan

Fea.ure selection(FS)pla.s a.crucial role in pre-processing ma.hine lea.ning da.a.ets,a. it elimina.es redunda.t fea.ures to improve cla.sifica.ion a.cura.y a.d reduce computa.ional *** pa.er presents a. enha.ced a.proa.h to FS for softwa.e fa.lt prediction,specifically by enha.cing the bina.y dwa.f mongoose optimiza.ion(BDMO)algorithm with a.crossover mecha.ism a.d a.modified positioning upda.ing *** proposed a.proa.h,termed iBDMOcr,a.ms to fortify explora.ion ca.a.ility,promote popula.ion diversity,a.d la.tly improve the wra.per-ba.ed FS process for softwa.e fa.lt prediction *** ga.ned superb performa.ce compa.ed to other well-esteemed optimiza.ion methods a.ross 17 benchma.k *** ra.ked first in 11 out of 17 da.a.ets in terms of a.era.e cla.sifica.ion ***,iBDMOcr outperformed other methods in terms of a.era.e fitness values a.d number of selected fea.ures a.ross all *** findings demonstra.e the effectiveness of iBDMOcr in a.dressing FS problems in softwa.e fa.lt prediction,lea.ing to more a.cura.e a.d efficient models.

关键词： Dwa.f mongoose optimiza.ion algorithm Optimiza.ion Fea.ure selection Cla.sifica.ion

Progress on ea.ly dia.nosing alzheimer’s disea.e

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Frontiers of Medicine 2024年第3期18卷 446-464页

作者： Yixin Chen Mura. al-Nusa.f Song Li Xia.g Ta. Huijia.Ya.g Hua.bin Ca. Weidong Le Lia.ning Provincial Key La.ora.ory for Resea.ch on the Pa.hogenic Mecha.isms of Neurological Disea.es The First Affiliated Hospital of Dalian Medical UniversityDalian116021China Tra.sgenic Section Laboratory of NeurogeneticsNational Institute on AgingNational Institutes of HealthBethesdaMD20892USA Institute of Neurology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChinese Academy of Sciences Sichuan Translational Medicine Research HospitalChengdu610072China

alzheimer’s disea.e(a.)is a.progressive neurodegenera.ive disorder tha. a.fects both cognition a.d non-cognition *** disea.e follows a.continuum,sta.ting with preclinical sta.es,progressing to mild cognitive a.d beha.ioral impa.rment,ultima.ely lea.ing to *** detection of a. is crucial for better dia.nosis a.d more effective ***,the current a. dia.nostic tests of bioma.kers using cerebrospinal fluid a.d/or bra.n ima.ing a.e inva.ive or expensive,a.d mostly a.e still not a.le to detect ea.ly disea.e ***,there is a. urgent need to develop new dia.nostic techniques with higher sensitivity a.d specificity during the preclinical sta.es of *** non-cognitive ma.ifesta.ions,including beha.ioral a.normalities,sleep disturba.ces,sensory dysfunctions,a.d physical cha.ges,ha.e been observed in the preclinical a. sta.e before occurrence of nota.le cognitive *** resea.ch a.va.ces ha.e identified several biofluid bioma.kers a. ea.ly indica.ors of *** review focuses on these non-cognitive cha.ges a.d newly discovered bioma.kers in a.,specifically a.dressing the preclinical sta.es of the ***,it is of importa.ce to explore the potential for developing a.predictive system or network to foreca.t disea.e onset a.d progression a. the ea.ly sta.e of a..

关键词： alzheimer’s disea.e ea.ly dia.nosis non-cognitive symptoms bioma.kers

a.Hybrid a.d Lightweight Device-to-Server a.thentica.ion Technique for the Internet of Things

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Computers, Ma.erials & Continua 2024年第3期78卷 3805-3823页

作者： Sha.a.al-Ota.bi Ra.im Kha. Ha.him ali a.ta. a.med Kha. a.ir Sa.ed Jeha. ali Depa.tment of Informa.ion Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Depa.tment of Computer Science Abdul Wali Khan University MardanMardan23200Pakistan Depa.tment of Computer Science a.d IT UET PeshawarJalozai Campus PeshawarPeshawar24240Pakistan Depa.tment of a. Convergence Network Ajou UniversitySuwon16499South Korea

The Internet of Things(IoT)is a.sma.t networking infra.tructure of physical devices,i.e.,things,tha. a.e embedded with sensors,a.tua.ors,softwa.e,a.d other technologies,to connect a.d sha.e da.a.with the respective server *** IoTs a.e cornerstones in different a.plica.ion doma.ns,the device’s a.thenticity,i.e.,of server(s)a.d ordina.y devices,is the most crucial issue a.d must be resolved on a.priority ***,va.ious field-proven methodologies were presented to strea.line the verifica.ion process of the communica.ing devices;however,loca.ion-a.a.e a.thentica.ion ha. not been reported a. per our knowledge,which is a.crucial metric,especially in scena.ios where devices a.e *** pa.er presents a.lightweight a.d loca.ion-a.a.e device-to-server a.thentica.ion technique where the device’s membership with the nea.est server is subjected to its loca.ion informa.ion along with other ***,Media.a.cess Control(Ma.)a.dress a.d a.va.ce Encryption Scheme(a.S)along with a.secret sha.ed key,i.e.,λ_(i) of 128 bits,ha.e been utilized by Trusted a.thority(Ta.to genera.e Ma.kIDs,which a.e used instea. of the original ID,for every device,i.e.,server a.d member,a.d a.e sha.ed in the offline ***,Ta.sha.es a.list of a.thentic devices,i.e.,server S_(j) a.d members C_(i),with every device in the IoT for the onwa.d verifica.ion process,which is required to be executed before the initializa.ion of the a.tual communica.ion ***,every device should be loca.ed such tha. it lies within the covera.e a.ea.of a.server,a.d this loca.ion informa.ion is used in the a.thentica.ion process.a.thorough a.alytical a.alysis wa. ca.ried out to check the susceptibility of the proposed a.d existing a.thentica.ion a.proa.hes a.a.nst well-known intruder a.ta.ks,i.e.,ma.-in-the-middle,ma.quera.ing,device,a.d server impersona.ions,etc.,especially in the IoT ***,proposed a.thentica.ion a.d existing sta.e-of-the-a.t a.proa.hes ha.e been s

关键词： Internet of things a.thenticity security loca.ion communica.ion

Ba.esia. a.d Non-Ba.esia. a.alysis for the Sine Generalized Linea. Exponential Model under Progressively Censored Da.a

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Computer Modeling in Engineering & Sciences 2024年第9期140卷 2795-2823页

作者： Na.f alota.bi a.S.al-Moisheer Ibra.im Elba.al Moha.med Elga.hy Eha. M.almetwally Depa.tment of Ma.hema.ics a.d Sta.istics Faculty of ScienceImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Saudi Arabia Depa.tment of Ma.hema.ics College of ScienceJouf UniversityP.O.Box 848Sakaka72351Saudi Arabia Ma.hema.ics a.d Computer Science Depa.tment Faculty of ScienceBeni-Suef UniversityBeni-Suef62521Egypt Depa.tment of Ba.ic Sciences Higher Institute of Administrative SciencesBelbeisEgypt Fa.ulty of Business a.ministra.ion Delta University for Science and TechnologyGamasa11152Egypt

This a.ticle introduces a.novel va.ia.t of the generalized linea. exponential(GLE)distribution,known a. the sine generalized linea. exponential(SGLE)*** SGLE distribution utilizes the sine tra.sforma.ion to enha.ce its *** upda.ed distribution is very a.a.ta.le a.d ma. be efficiently used in the modeling of survival da.a.a.d dependa.ility *** suggested model incorpora.es a.ha.a.d ra.e function(HRF)tha. ma. displa. a.rising,J-sha.ed,or ba.htub form,depending on its unique *** model includes ma.y well-known lifespa. distributions a. sepa.a.e *** suggested model is a.compa.ied with a.ra.ge of sta.istical *** model pa.a.eters a.e exa.ined using the techniques of ma.imum likelihood a.d Ba.esia. estima.ion using progressively censored *** order to evalua.e the effectiveness of these techniques,we provide a.set of simula.ed da.a.for testing *** releva.ce of the newly presented model is shown via.two real-world da.a.et a.plica.ions,highlighting its superiority over other respected simila. models.

关键词： Sine G fa.ily generalized linea. fa.lure ra.e progressively censored da.a moments ma.imum likelihood estima.ion Ba.esia. estima.ion simula.ion

Enha.cing Network Design through Sta.istical Evalua.ion of Ma.ET Routing Protocols

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Computers, Ma.erials & Continua 2024年第7期80卷 319-339页

作者： Ibra.im ala.eri Ta.fik al-Ha.hra.i a.jum Na.ir a.dulsa.a. Ebra.im Ya.ya.a.ef Gha.bi Fa.ulty of Medical Sciences Jabir ibn Hayyan Medical UniversityAlkufa QuNajaf54001Iraq Computer Science Depa.tment School of Science and TechnologyNottingham Trent UniversityNottinghamNG118NSUK Depa.tment of Computing Faculty of Engineering Sciences&Technology(FEST)Hamdard UniversityKarachi74600Pakistan Depa.tment of Informa.ion Technology College of Computing and Information TechnologyNorthern Border UniversityArar91431Saudi Arabia Depa.tment of Informa.ion System College of Computing and Information TechnologyNorthern Border UniversityArar91431Saudi Arabia

This pa.er contributes a.sophistica.ed sta.istical method for the a.sessment of performa.ce in routing protocols salient Mobile a. Hoc Network(Ma.ET)routing protocols:Destina.ion Sequenced Dista.ce Vector(DSDV),a. hoc On-Dema.d Dista.ce Vector(a.DV),Dyna.ic Source Routing(DSR),a.d Zone Routing Protocol(ZRP).In this pa.er,the evalua.ion will be ca.ried out using complete sets of sta.istical tests such a. Kruskal-Wallis,Ma.n-Whitney,a.d *** a.ticula.es a.systema.ic evalua.ion of how the performa.ce of the previous protocols va.ies with the number of nodes a.d the mobility *** study is premised upon the Quality of Service(QoS)metrics of throughput,pa.ket delivery ra.io,a.d end-to-end dela. to ga.n a. a.equa.e understa.ding of the opera.ional efficiency of ea.h protocol under different network *** findings expla.ned significa.t differences in the performa.ce of different routing protocols;a. a.result,decisions for the selection a.d optimiza.ion of routing protocols ca. be ta.en effectively a.cording to different network *** pa.er is a.step forwa.d in the general understa.ding of the routing dyna.ics of Ma.ETs a.d contributes significa.tly to the stra.egic deployment of robust a.d efficient network infra.tructures.

关键词： Routing protocols sta.istical a.proa.h friedma. Ma.ET

Deferred reva.cula.iza.ion in dia.etic pa.ient a.cording to combined inva.ive functional a.d intra.a.cula. ima.ing da.a.a.ca.e report

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World Journal of Clinical Ca.es 2024年第13期12卷 2269-2274页

作者： a.if al Noorya.i Wa.l a.oushokka.Bra.ko Beleslin Bilja.a.Nedeljkovic-Beleslin Depa.tment of Ca.diology Al Qassimi HospitalSharjah 1234United Arab Emirates Depa.tment of Ca.diology Medical FacultyUniversity of BelgradeBelgrade 11000Serbia Institute of Endocrinology Diabetes and Metabolic DisordersUniveristy Clinical Center of SerbiaBelgrade 11000Serbia Depa.tment of Internal Medicine/Endocrinology Medical facultyUniversity of BelgradeBelgrade 11000Serbia

Ba.KGROUND Inva.ive functional evalua.ion by fra.tional flow reserve(FFR)is considered a. a.gold sta.da.d for the evalua.ion of intermedia.e corona.y ***,in pa.ients with dia.etes due to a.celera.ed progression of a.herosclerosis the outcome ma. be worse even in the presence of nega.ive functional *** SUMMa.Y We present a.ca.e of 55-yea.-old male dia.etic pa.ient who wa. a.mitted for chest *** corona.y a.giogra.hy disclosed 2 intermedia.e stenoses of the obtuse ma.ginal bra.ch with no evidence of restenosis on previously impla.ted *** undergone inva.ive functional testing of intermedia.e lesion with preserved FFR(0.88),low corona.y flow reserve(1.2)a.d very high index of microva.cula. resista.ce(84).Due to discrepa.cy in inva.ive functional pa.a.eters,intra.a.cula. ima.ing with optical coherence tomogra.hy showed fibrotic stenoses without signs of thin-sup *** of the preserved FFR a.d no signs of vulnera.le pla.ue,the interventional procedure wa. deferred a.d the pa.ient continued with optimal *** Combined functional a.d a.a.omic ima.ing of intermedia.e corona.y stenosis in dia.etic pa.ients represent comprehensive contempora.y decision pa.hwa. in the ma.a.ement of the pa.ients.

关键词： Fra.tional flow reserve Corona.y flow reserve Index of microva.cula. resista.ce Optical coherence tomogra.hy Intermedia.e corona.y stenosis Ca.e report

Gut microbiota.predicts the dia.nosis of ulcera.ive colitis in Sa.di children

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World Journal of Clinical Pedia.rics 2024年第1期13卷 118-124页

作者： Moha.ma. El Mouza. a.med al Sa.khy a.a.d a.siri Depa.tment of Pedia.rics Gastroenterology UnitKing Saud UniversityRiyadh 11461Saudi Arabia

Ba.KGROUND Ulcera.ive colitis(UC)is a. immune-media.ed chronic infla.ma.ory condition with a.worldwide *** the etiology of this disea.e is still unknown,the understa.ding of the role of the microbiota.is becoming increa.ingly *** To investiga.e the predictive power of the gut microbiota.for the dia.nosis of UC in a.cohort of newly dia.nosed trea.ment-na.ve Sa.di children with *** The study popula.ion included 20 children with a.confirmed dia.nosis of UC a.d 20 healthy *** DNa.wa. extra.ted a.d sequenced,a.d shotgun meta.enomic a.alysis wa. performed for ba.teria.a.d *** a.d bioinforma.ics demonstra.ed significa.t dysbiosis in the form of reduced alpha.diversity,beta.diversity,a.d significa.t difference of a.unda.ce of ta.a.between children with UC a.d control *** receiver opera.ing cha.a.teristic curve,a.proba.ility curve,wa. used to determine the difference between the UC a.d control *** a.ea.under the curve(a.C)represents the degree of sepa.a.ility between the UC group a.d the control *** a.C wa. calcula.ed for all identified ba.terial species a.d for ba.terial species identified by the ra.dom forest cla.sifica.ion algorithm a. importa.t potential bioma.kers of UC.a.simila. method of a.C calcula.ion for all ba.teriopha.es a.d importa.t species wa. *** The media. a.e a.d ra.ge were 14(0.5-21)a.d 12.9(6.8-16.3)yea.s for children with UC a.d controls,respectively,a.d 40%a.d 35%were male for children with UC a.d controls,*** a.C for all identified ba.terial species wa. 89.5%.However,when using the ba.terial species identified a. importa.t by ra.dom forest cla.sifica.ion algorithm a.alysis, the a.cura.y increa.ed to 97.6%. Simila.ly, the a.C for all theidentified ba.teriopha.es wa. 87.4%, but this value increa.ed to 94.5% when the importa.t ba.teriopha.ebioma.kers were *** very high to excellent a.Cs of fecal ba.terial a.d viral species sugge

关键词： Ulcera.ive colitis Microbiota a.ea.under the curve Children Sa.di a.a.ia