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Usefulness of ultrasonography to assess the response to steroidal therapy for the rare case of type 2b immunoglobulin G4-related sclerosing cholangitis without pancreatitis:A case report

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World Journal of Clinical Cases 2020年第22期8卷 5821-5830页

作者： Yuto Tanaka Kenya Kamimura Ryota Nakamura Marina Ohkoshi-yamada Yohei Koseki Takeshi Mizusawa Satoshi Ikarashi Kazunao Hayashi Hiroki Sato akira Sakamaki Junji Yokoyama Shuji Terai Division of Gastroenterology and Hepatology Graduate School of Medical and Dental SciencesNiigata UniversityNiigata 9518510Japan

BACKGROUND A type 2b immunoglobulin G4(IgG4)-related sclerosing cholangitis(SC)without autoimmune pancreatitis is a rare condition with *** the variety of the imaging modalities have tested its usefulness in diagnosing the IgG4-SC,however,the usage of ultrasonography for the assessment of the response to steroidal therapy on the changes of bile duct wall thickness have not been reported in the ***,the information of our recent case and reported cases have been *** SUMMARY We report the case of an 82-year-old Japanese man diagnosed with isolated IgG4-related SC based on the increase of serum IgG4,narrowing of the bile duct,its wall thickness,no complication of autoimmune pancreatitis,and IgG4 positive inflammatory cell infiltration to the wall with the fibrotic *** cholangiogram revealed type 2b according to the *** treatment showed a favorable effect,with the smooth decrease in serum IgG4 and the improvement of the bile duct wall *** As isolated type 2b,IgG4-SC is rare,the images,histological findings,and clinical course of our case will be helpful for physicians to diagnose and treat the new cases appropriately.

关键词： Immunoglobulin G4-related sclerosing cholangitis Type 2b Corticosteroid Autoimmune pancreatitis Ultrasonography Imaging Case report

Luminescence of Er^(3+) in Oxyfluoride Transparent Glass-Ceramics

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Journal of Rare Earths 2006年第6期24卷 699-705页

作者： akira Ueda Steven H Morgan Richard Mu Department of Physics Fisk University NashvilleTN 37208 USA

Erbium doped silicate, germanate, and tellurium-germanate oxyfluoride glasses were prepared in a bulk form. Through appropriate heat treatment of the as-prepared glasses, transparent glass-ceramics （TGCs） were obtained with the formation of β-PbF2：Er^3＋ nanocrystals in the glass matrix were confirmed by X-ray ***-defined diffraction peaks were observed in the samples after heat-treatment. The average crystal diameter of these precipitated crystals from full-width at half-maximum （FWHM） of the diffraction peak was estimated to be between 8 and 13 nm. Optical absorption, photoluminescence, and upconversion luminescence were measured on as-prepared glass and glass-ceramics. Luminescence spectra in the TGC samples revealed well-resolved, sharp stark-splitting peaks, which indicates that a majority of Er^3＋ ions has been incorporated into the crystalline phase of the nanocrystals. The intensity of the visible and near infrared luminescence mostly increases in TSG compared to that in the as-prepared glass. In 1.53 μm absorption and emission bands, the maximum absorption peak is blue-shifted from 1531 to 1507 nm, whereas the maximum emission peak is redshifted from 1535 to 1543 nm in TGC, as compared with that in glass. The bandwidth at half-maximum （BWHM） of the emission band is significantly broader in TGC than in glass, which is beneficial to the erbium-doped fiber amplifier （EDFA）. Upconversion luminescence was measured using 800 nm near-infrared light excitation. Drastically increased upconversion 1 was observed from the TGC as compared to that from their corresponding as-prepared glasses. In addition to a strong green emission centered at 545 nm because of ^4S3/2→^4I15/2 transition and a weaker red emission centered at 662 nm because of ^4F9/2→^4I15/2 transition, generally seen from the Er^3＋ doped glasses, two violet emissions centered at 410 nm because of ^2H9/2→^4I15/2 transition and centered at 379 nm because of ^4G11/2→^4I15/2 transition were also o

关键词： luminescence transparent glass-ceramics rare earths

Analysis and control of vibration of ropes in a high-rise elevator under earthquake excitation

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Earthquake Engineering and Engineering Vibration 2019年第2期18卷 447-460页

作者： Thuan Xuan Nguyen Nanako Miura akira Sone Faculty of Mechanical Engineering Kyoto Institute Technology Matsugasaki

In this research, the vibration of elevator ropes, including the main rope and compensation rope are investigated simultaneously in a high-rise elevator system under earthquake excitation. Moreover, the paper presents a new control method to restrain the sway of both ropes. This study considers varying rope lengths during elevator operation which cause other system parameters such as natural frequency, and damping ratio to be time-variant variables. The dynamics of the ropes are analyzed by solving the governing non-stationary, nonlinear equation numerically. In order to mitigate the vibration of ropes in several motion conditions, particularly upwards movement, downward movement, stopped at the lowest position, and stopped at the highest position, an active equipment is installed at the compensation sheave. The stability of the system using the controller is analyzed at four states: without disturbance and static car, without disturbance and mobile car, including disturbance and static car, and including disturbance and mobile car. The efficiency of the controller used for dampening the vibration of elevator ropes is validated by numerical simulation results.

关键词： elevator ropes high-rise elevator vibration controller stability

IMMERSIVE VR VISUALIZATIONS BY VFIVE PART 1: DEVELOPMENT

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International Journal of Modeling, Simulation, and Scientific Computing 2013年第S1期4卷 40-53页

作者： akira KAGEYAMA NOBUAKI OHNO Graduate School of System Informatics Kobe University Kobe657-8501Japan Graduate School of Simulation Studies University of Hyogo Kobe650-0047Japan

We have been developing a visualization application for CAVE-type virtual reality(VR)systems for more than a *** application,VFIVE,is currently used in several CAVE systems in Japan for routine *** is also used as a b... 详细信息

关键词： Virtual reality CAVE immersive display system.

A Novel Sterilization Method Using Pulsed Discharge Plasma

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Chinese Physics Letters 1998年第1期15卷 41-42页

作者： WANG Xi-lu akira Mizuno Shijin Katsura Department of Ecological Engineering Toyohashi University of TechnologyTempaku-choToyohashi441Japan Institute of Electrostatics Northeast Normal UniversityChangchun 130024

Pulsed discharge plasma(PDP)has been used to kill bacteria and the curves of the survival rate of bacteria against treatment time are *** structural change in the cell membrane is caused by PDP and the cell is thus **... 详细信息

关键词： PDP Plasma treatment

Lyapunov function-based obstacle avoidance scheme for a two-wheeled mobile robot

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控制理论与应用（英文版） 2008年第4期6卷 399-404页

作者： akira INOUE Katsuya SEKIGUCHI Department of Systems Engineering

An obstacle avoidance scheme of a two-wheeled mobile robot is shown by selecting an appropriate Lya- punov function. When considering the obstacle, the Lyapunov function may have some local minima. A method which erases the local minima is proposed by using a function which covers the minima with a plane surface. The effectiveness of the proposed method is verified by numerical simulations.

关键词： Obstacle avoidance Lyapunov function Mobile robot Robot control

Improving quality measures in colonoscopy and its therapeutic intervention

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World Journal of Gastroenterology 2014年第36期20卷 13027-13034页

作者： akira Horiuchi Naoki Tanaka Digestive Disease Center Showa Inan General Hospital Komagane 399-4117 Japan Laboratory of Metabolism National Cancer Institute National Institutes of Health Bethesda MD 20892 United States

Colonoscopy with polypectomy has been shown to reduce the risk of colon cancer. The critical element in the quality of colonoscopy in terms of polyp detection and removal continues to be the performance of the endoscopist, independent of patient-related factors. Improved results in terms of polyp detection and complete removal have implications regarding the development of screening and surveillance intervals and the reduction of interval cancers after negative colonoscopy. Advances in colonoscopy techniques such as high-definition colonoscopy, hood-assisted colonoscopy and dye-based chromoendoscopy have improved the detection of small and flat-type colorectal polyps. Virtual chromoendoscopy has not proven to improve polyp detection but may be useful to predict polyp pathology. The majority of polyps can be removed endoscopically. Available polypectomy techniques include cold forceps polypectomy, cold snare polypectomy, conventional polypectomy, endoscopic mucosal resection and endoscopic submucosal dissection. The preferred choice depends on the polyp size and characteristics. Other useful techniques include colonoscopic hemostasis for acute colonic diverticular bleeding, endoscopic decompression using colonoscopic stenting, and transanal tube placement for colorectal obstruction. Here we review the current knowledge concerning the improvement of quality measures in colonoscopy and colonoscopy-related therapeutic interventions.

关键词： Colonoscopy Polypectomy Hemostasis Endoscopic decompression Colorectal polyp Colonic diverticular bleeding Colorectal obstruction Gastrointestinal endoscopy

Therapeutic approaches targeting intestinal microflora in inflammatory bowel disease

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World Journal of Gastroenterology 2006年第28期12卷 4452-4460页

作者： akira Andoh Yoshihide Fujiyama Department of Internal Medicine Shiga University of Medical ScienceSeta TukinowaOtsu 520-2192Japan

Inflammatory bowel diseases, ulcerative colitis, and Crohn＇s disease, are chronic intestinal disorders of unknown etiology in which in genetically susceptible individuals, the mucosal immune system shows an aberrant response towards commensal bacteria. The gastrointestinal tract has developed ingenious mechanisms to coexist with its autologous microflora, but rapidly responds to invading pathogens and then returns to homeostasis with its commensal bacteria after the pathogenic infection is cleared. In case of disruption of this tightly-regulated homeostasis, chronic intestinal inflammation may be induced. Previous studies showed that some commensal bacteria are detrimental while others have either no influence or have a protective action. In addition, each host has a genetically determined response to detrimental and protective bacterial species. These suggest that therapeutic manipulation of imbalance of microflora can influence health and disease. This review focuses on new insights into the role of commensal bacteria in gut health and disease, and presents recent findings in innate and adaptive immune interactions. Therapeutic approaches to modulate balance of intestinal microflora and their potential mechanisms of action are also discussed.

关键词： Commensal bacteria Prebiotics Probiotics Innate immunity

Limb Stiffness Improvement of the Robot WAREC-1R for a Faster and Stable New Ladder Climbing Gait

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Journal of Bionic Engineering 2023年第1期20卷 57-68页

作者： Xiao Sun akira Ito Takashi Matsuzawa Atsuo Takanishi Department of Mechatronics University of YamanashiYamanashi400-8511Japan Faculty of Science and Engineering Waseda UniversityTokyo162-8480Japan

Ladder climbing is a relatively new but practical locomotion style for robots. Unfortunately, due to their size and weight, ladder climbing by human-sized robots developed so far is struggling with the speedup of ladder climbing motion itself. Therefore, in this paper, a new ladder climbing gait for the robot WAREC-1R is proposed by the authors, which is both faster than the former ones and stable. However, to realize such a gait, a point that has to be taken into consideration is the deformation caused by the self-weight of the robot. To deal with this issue, extra hardware (sensor) and software (position and force control) systems and extra time for sensing and calculation were required. For a complete solution without any complicated systems and time only for deformation compensation, limb stiffness improvement plan by the minimal design change of mechanical parts of the robot is also proposed by the authors, with a thorough study about deformation distribution in the robot. With redesigned parts, ladder climbing experiments by WAREC-1R proved that both the new ladder climbing gait and the limb stiffness improvement are successful, and the reduced deformation is very close to the estimated value as well.

关键词： Ladder climbing Legged robot Bionic robot Gait.Stiffness improvement Finite element analysis