检索结果-南通市图书馆

妊娠期高血压后遵循医师优化的自我管理长期血压控制:医生优化产后高血压治疗(POP-HT)随机临床试验

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华高血压杂志（中英文） 2024年第2期32卷 179-179页

作者：袁源(译) 郑武洪(审校) 不详

妊娠期高血压可致不良心脏重构,晚年高血压和心血管疾病风险升高。本研究旨在探究设计一种实现更好血压控制的产后干预方案,能否比常规门诊护理在产后头9月期间获得更低的血压。设计、设置和参与者:在英国一家医院中设计随机、开放标签... 详细信息

妊娠期高血压可致不良心脏重构,晚年高血压和心血管疾病风险升高。本研究旨在探究设计一种实现更好血压控制的产后干预方案,能否比常规门诊护理在产后头9月期间获得更低的血压。设计、设置和参与者:在英国一家医院中设计随机、开放标签、盲法、终点试验。纳入年龄≥18岁,妊娠子痫前期或妊娠期高血压后,产后出院需要降压药治疗的女性为研究对象。

关键词：妊娠期高血压随机临床试验血压控制降压药治疗门诊护理心脏重构高血压治疗盲法

Emerging and re-emerging human infectious diseases:A systematic review of the role of wild animals with a focus on public health impact

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2020年第3期13卷 99-106页

作者： Marli c cupertino Michely B Resende Nicholas aj Mayers Lorendane M carvalho Rodrigo Siqueira-Batista Medical School Faculdade Dinamica do Vale do Piranga.Ponte Nova.Minas GeraisBrazil Laboratory of Epidemiological and computational Methods in Health Department of Medicine and NursingUniversidade Federal de Vicosa.Minas GeraisBrazil Department of Veterinary Medicine Universidade Federal de Vicosa.Vicosa.Minas GeraisBrazil

Infectious diseases continue to impose unpredictable burdens on global health and economies, a subject that requires constant research and updates. In this sense, the objective of the present article was to review studies on the role of wild animals as reservoirs and/or dispersers of etiological agents of human infectious diseases in order to compile data on the main wild animals and etiological agents involved in zoonotic outbreaks. A systematic review was carried out using PRISMA guidelines, using the PubMed, Scopus and SciELO platforms as data banks. The descriptors used were "zoonosis", "human infectious diseases" and "wild animals". The results show that wild animals(mainly bats, birds and primates) play an important role in the dissemination of etiological agents(mainly viruses, as a new coronavirus called 2019 Novel coronavirus) in extensive geographic regions. Moreover, these wild animal organisms can act as the site for essential biotic synergy among several pathogenic microorganisms, promoting a higher rate of adaptation, mutation and even genetic recombination, with consequent stimulation of new strains and subtypes, inducing new infectious agents with unknown virulent potential. In conclusion, the monitoring of these diseases and adequate preparation for possible epidemics and pandemics are fundamental conditions for the mitigation of their future impact. The zoonotic threat of these etiological agents and the impact on public health can be enormous as shown by the ongoing epidemic of 2019 novel coronavirus(2019-ncoV) infections.

关键词： Zoonosis Epidemics 2019-ncoV Virology Epidemiology

cOVID-19 in Brazil:Epidemiological update and perspectives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2020年第5期13卷 193-196页

作者： Marli c cupertino Graziela A cupertino Andréia P Gomes Nicholas aj Mayers R Siqueira-Batista Medical School Faculdade Dinamica do Vale do PirangaPonte NovaMinas GeraisBrazil Laboratory of Epidemiological and computational Methods in Health Department of Medicine and NursingUniversidade Federal de VicosaVicosaMinas GeraisBrazil Department of Veterinary Medicine Universidade Federal de VicosaVicosaMinas GeraisBrazil

coronaviruses are RNA viruses (Family: coronaviridae) constituents of a significant number of viruses that provoke diseases in animals and human beings. There are four genera of these microorganisms: Alphacoronavirus, Betacoronavirus, Deltacoronavirus and Gammacoronavirus. From this group, the alpha- and beta-coronaviruses are designated as human coronavirus (HcoV) for their propensity to infect human beings[1].

关键词： diseases corona Brazil

Ternary Pt/Re/SnO2/c catalyst for EOR:Electrocatalytic activity and durability enhancement

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2020年第3期13卷 832-842页

作者： Elzbieta Drzymala Grzegorz Gruze Joanna Depciuch Miroslawa Pawlyta Mikołaj Donten Magdalena Parlinska-Wojtan Institute of Nuclear Physics Polish Academy of Sciences PL-31342 KrakowPoland Institute of Engineering Materials and Biomaterials Silesian University of TechnologyGliwice 44-100Poland Faculty of chemistry University of WarsawWarsaw 02-093Poland

carbon-supported Pt/c,Pt/Re/c,Pt/SnO2/c and Pt/Re/SnO2/c,with 20 wt.%overall metal loading were prepared and their electrochemical activity towards ethanol oxidation reaction(EOR)was *** electron microscopy(TEM)combined with energy dispersive X-ray spectroscopy(EDS)revealed,that indeed binary and ternary combinations of the designed nanoparticles(NPs)were formed and successfully uniformly deposited on a carbon *** transform infrared spectroscopy(FTIR)allowed to assess the chemical composition of the nanocatalysts and X-ray diffraction(XRD)allowed to determine the catalyst *** and chronoamperometric measurements were used to establish its catalytic activity and *** influence of Re addition on the electrochemical activity towards ethanol oxidation reaction(EOR)was ***,the addition of Re to the binary Pt/SnO2/c catalyst leads to the formation of ternary Pt/Re/SnO2/c with physical contact between the individual NPs,enhancing the ***,the onset potential of the synthesized ternary catalyst is shifted to more negative potentials and the current densities and specific activity are nearly 11 and 5 times higher,respectively,than for commercial Pt *** ternary Pt/Re/SnO2/c catalyst retained 96%of its electrochemical surface area.

关键词： chemical synthesis transmission electron microscopy(TEM)characterization electrochemistry ethanol oxidation reaction(EOR) Pt/Re/SnO2/c catalysts ternary catalysts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

奥美拉唑致低胃酸对营养素吸收影响的研究

中华消化杂志 1999年第S1期19卷 24-27页

作者：郑家驹汤光文 Turnball aj Serfaty Lacrosniere c 江苏省苏州市第三人民医院 215008

目的　对奥美拉唑（ＯＭ）致低胃酸的人体与动物模型进行矿物质与微量元素（钙、磷、镁与锌）吸收，以及血浆β胡萝卜素水平的研究。方法与结果　实验一（全胃肠道灌洗吸收法）表明，健康成人口服ＯＭ（４０ｍｇ／ｄ，共９天），... 详细信息

目的　对奥美拉唑（ＯＭ）致低胃酸的人体与动物模型进行矿物质与微量元素（钙、磷、镁与锌）吸收，以及血浆β胡萝卜素水平的研究。方法与结果　实验一（全胃肠道灌洗吸收法）表明，健康成人口服ＯＭ（４０ｍｇ／ｄ，共９天），及给以外源性盐酸（０．１Ｍ，１２０ｍｌ）后，均不影响食物中矿物质的吸收；实验二发现，口服ＯＭ（４０ｍｇ，每日２次，共９天）后，人体血清中总的β胡萝卜素水平升高反应低于对照组；实验三提示，上述ＯＭ剂量致低胃酸时，小肠细菌过度生长，但细菌并未与β胡萝卜素结合而干扰其肠内吸收；实验四表明，ＯＭ诱致低胃酸并不影响大鼠肠道锌吸收。结论　这些实验结果提示膳食中的Ｈ＋可能具有代偿低胃酸对营养素吸收影响的作用。

关键词：胃酸矿物质 β-胡萝卜素

Genome size evolution of the extant lycophytes and ferns

在线全文

学校读者我要写书评

暂无评论

Plant Diversity 2022年第2期44卷 141-152页

作者： Fa-Guo Wang Ai-Hua Wang cheng-Ke Bai Dong-Mei Jin Li-yun Nie aj Harris Le che Juan-JuanWang Shi-yu Li Lei Xu Hui Shen yu-Feng Gu Hui Shang Lei Duan Xian-chun Zhang Hong-Feng chen yue-Hong yan Key Laboratory of Plant Resources conservation and Sustainable Utilization Guangdong Provincial Key Laboratory of Applied BotanySouth China Botanical GardenChinese Academy of SciencesGuangzhou510650China college of Life Sciences Shaanxi Normal UniversityXi'an710062China Eastern china conservation centre for Wild Endangered Plant Resources Shanghai Chenshan Botanical GardenShanghai201602China Key Laboratory of Environment change and Resources Use in Beibu Gulf Ministry of EducationNanning Normal UniversityNanning530001China Department of Biology Oberlin CollegeOberlinOH44074USA State Key Laboratory of Systematic and Evolutionary Botany Institute of BotanyChinese Academy of SciencesBeijing100093China Key Laboratory of National Forestry and Grassland Administration for Orchid conservation and Utilization the National Orchid Conservation Center of China and the Orchid Conservation&Research Center of Shenzhen518114ShenzhenChina Life Science and Technology college Harbin Normal UniversityHarbin150025China

Ferns and lycophytes have remarkably large ***,little is known about how their genome size evolved in fern *** explore the origins and evolution of chromosome numbers and genome size in ferns,we used flow cytometry to measure the genomes of 240 species(255 samples)of extant ferns and lycophytes comprising 27 families and 72 genera,of which 228 species(242 samples)represent new *** analyzed correlations among genome size,spore size,chromosomal features,phylogeny,and habitat type preference within a phylogenetic *** also applied ANOVA and multinomial logistic regression analysis to preference of habitat type and genome *** the phylogeny,we conducted ancestral character reconstruction for habitat types and tested whether genome size changes simultaneously with shifts in habitat *** found that 2 c values had weak phylogenetic signal,whereas the base number of chromosomes(x)had a strong phylogenetic ***,our analyses revealed a positive correlation between genome size and chromosome traits,indicating that the base number of chromosomes(x),chromosome size,and polyploidization may be primary contributors to genome expansion in ferns and *** sizes in different habitat types varied significantly and were significantly correlated with habitat types;specifically,multinomial logistic regression indicated that species with larger 2 c values were more likely to be *** habitat is inferred to be ancestral for both extant ferns and lycophytes,whereas transitions to other habitat types occurred as the major clades *** in habitat types appear be followed by periods of genomic *** on these results,we inferred that habitat type changes and multiple whole-genome duplications have contributed to the formation of large genomes of ferns and their allies during their evolutionary history.

关键词： Genome size Ferns chromosome numbers Habitat type Whole-genome duplications Evolution

机械负荷调节猪腰椎间盘细胞表达α5β1整合素的体外研究

在线全文

学校读者我要写书评

暂无评论

中华骨科杂志 2006年第6期26卷 415-420页

作者：于胜吉邱贵兴 yang B Roth S Whyne c yee aj 北京协和医院骨科 100730 中国医学科学院肿瘤医院骨科 The Spine Program Division of Orthopaedic Surgery Sunnybrook ＆ Women＇s College HSC University of Toronto Canada

目的研究α5β1整合素在体外培养的猪腰椎间盘细胞中的表达和机械负荷对其的影响。方法取10只年龄5～6周、体重25～30kg的猪,处死后12h内,无菌条件下切取完整的腰椎,剔除腰椎周围的韧带和软组织,尤其是椎间盘周围的韧带。从腹侧一次性... 详细信息

目的研究α5β1整合素在体外培养的猪腰椎间盘细胞中的表达和机械负荷对其的影响。方法取10只年龄5～6周、体重25～30kg的猪,处死后12h内,无菌条件下切取完整的腰椎,剔除腰椎周围的韧带和软组织,尤其是椎间盘周围的韧带。从腹侧一次性切开椎间盘取出髓核(nucleuspulpous,NP),仔细分离纤维环(anulusfibrous,AF),将两者立即置于Hanks平衡盐溶液中,制成细胞悬液。分别对腰椎间盘的AF和NP细胞施加1MPa、1Hz,3h/d,共3d的周期性液压,通过对细胞的形态学观察、Western免疫印迹和免疫组织化学染色,检测α5β1整合素在正常腰椎间盘AF细胞和NP细胞中的表达及周期性压力对其的影响。结果经周期性液压后,NP细胞的存活率大于90%,AF细胞的存活率大于85%,加压后的AF细胞和NP细胞均可见体积缩小。α5β1整合素在正常腰椎间盘AF细胞和NP细胞中的表达呈强阳性。Western免疫印迹结果显示:加压后α5β1整合素在AF细胞中的表达均明显减少,P值分别为0.000、0.003,与对照组比较差异有统计学意义;α5β1整合素在NP细胞中的表达也明显减少,P值分别为0.001、0.015,与对照组比较差异有统计学意义。结论机械负荷可引起腰椎间盘细胞中α5β1整合素的变化,提示α5β1整合素在腰椎间盘细胞中可能发挥力学传感器的作用。

关键词：整合素α5β1 椎间盘动力传导,细胞

Room-temperature deposition of yttria-stabilized zirconia buffer layer on metallic substrates by laser ablation

在线全文

学校读者我要写书评

暂无评论

chinese Science Bulletin 1997年第16期42卷 1345-1350页

作者： Xiong, XM Zhou, yL chen, ZH Lu, HB Zhu, aj cui, DF Wang, HS yang, GZ chinese Acad Sci Inst Phys Lab Opt Phys Beijing 100080 Peoples R China chinese Acad Sci Ctr Condensed Matter Phys Beijing 100080 Peoples R China

THE preparation of high-temperature superconducting (HTSc) wires or tapes is very important for the power application of HTSc. High-J_c properties of y-Ba-cu-O thin film at liq uid-nitrogen temperature are very attractive not only for small-sized electronic devices, but also for large-scale applications such as high-power transmission cables, high-field magnets and large-scale microwave components. Large-current power application would be achieved if high-J_c yBcO films were grown on practical cheap and flexible metallic substrates. An yttria-stabi-

关键词： ySZ low temperature PLD buffer layer metal substrate.

周期性压力下椎间盘细胞中肌动蛋白的变化及其意义

在线全文

学校读者我要写书评

暂无评论

中华骨科杂志 2005年第9期25卷 52-56页

作者：于胜吉邱贵兴 yang BL Roth S Whyne c yee aj 北京协和医院骨科 The Spine Program Division of Or-thopaedic Surgery Sunnybrook & Women's College HSC University ofToronto Canada

目的探讨在周期性压力下,体外培养的椎间盘细胞中的肌动蛋白的变化及其意义。方法采用10只5～6周龄、体重为25～30kg的猪的椎间盘进行体外细胞的分离和培养,对细胞施加周期性液压,通过对细胞的形态学观察及Western免疫印迹和免疫荧光实... 详细信息

目的探讨在周期性压力下,体外培养的椎间盘细胞中的肌动蛋白的变化及其意义。方法采用10只5～6周龄、体重为25～30kg的猪的椎间盘进行体外细胞的分离和培养,对细胞施加周期性液压,通过对细胞的形态学观察及Western免疫印迹和免疫荧光实验,检测在周期性压力下椎间盘细胞中的肌动蛋白的变化。结果纤维环细胞和髓核细胞经1MPa、1Hz,持续每天3h加压,3d后髓核细胞的存活率大于90%,纤维环细胞的存活率大于85%,加压后的纤维环细胞和髓核细胞体积均缩小,由多角形转变为细长形。Western免疫印迹结果显示,肌动蛋白在纤维环细胞和髓核细胞中的表达均明显减少,以髓核细胞为著。免疫荧光结果显示,肌动蛋白由正常纤维环细胞和髓核细胞内的疏松排列转变为受压细胞内的紧密排列,髓核细胞的体积明显缩小,其中的肌动蛋白在细胞膜周围紧密排列。结论体外培养的单层椎间盘细胞在受力状态下,肌动蛋白的表达减少,细胞的体积缩小,并且肌动蛋白在细胞内重排列。这可能是激发细胞内或细胞表面信号传导的重要机制。

关键词：肌动蛋白类椎间盘细胞