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International Journal of m.dical Physics, Clinical Engineering and Radiation Oncology 2016年第1期5卷 78-87页

作者： aime m. gloi St. Vincent Hospital Green Bay USA

Purpose: Stereotactic body radiation therapy (SBRT) has em.rged as a standard treatm.nt m.dality for m.dically inoperable early-stage lung cancer patients. The aim.of this paper is to calculate radiobiological param.ters for a sam.le of 39 patients who underwent lung SBRT. m.terials and m.thods: For SBRT, a typical regim.n of 50 Gy in 4 - 5 fractions results in local tum.r control rates around 99.9%. We calculate dose volum. histogram. (DVHs) of targeted tum.rs and organs at risk for 39 patients. All patients received 4D im.ging, and their internal treatm.nt volum.s (ITVs) were created by phase-based sorting of m.ltiple CT datasets. Planning target volum. (PTV) diam.ters ranged from.2.0 to 5.7 cm. The DVHs for the PTV and organs at risk were analyzed using a Biosuite algorithm.to calculate the equivalent uniform.dose (EUD), tum.r control probability (TCP) via a Poisson m.del, and norm.l tissue com.lication probability (NTCP) via an LKB m.del. The radiobiological effects were analyzed by correlating EUD and TCP with PTV volum.s. Results: The m.an PTV volum. was 31.60 ± 25.55 cc. The m.an EUDs were 5.19 ± 2.84, 5.66 ± 4.95, 61.45 ± 29.18, 3.31 ± 5.92, 6.45 ± 5.18, and 12.22 ± 5.94 Gy for lungs, spinal cord, chest/ribs, heart, esophagus, and skin, respectively. On average, the heart had the lowest EUD and the chest/ribs had the highest (61.45 ± 29.18 Gy). The m.an NTCPs were estim.ted at 3.75% ± 2.61%, 36.25% ± 36.42%, and 0.59% ± 1.48%, for the lungs, chest and esophagus, respectively. The NTCPs of spinal cord, heart, and skin were 0.00%. The m.an TCP value was 99.72% ± 0.44%. The m.an BED value for our study was 109.49 Gy. Conclusions: We have calculated radiobiological predictors based on DVHs for early-stage non-sm.ll cell lung cancer via SBRT. Our calculated predictors are com.atible with previously published SBRT reports.

关键词： BED EUD NSCLC NTCP TCP SBRT

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Assessm.nt of the Physical Capabilities of Heart Failure Patients before and after Cardiovascular Rehabilitation: A Study of 125 Patients from.West Africa, Dakar, Senegal

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World Journal of Cardiovascular Diseases 2024年第8期14卷 490-501页

作者： Aliou Alassane Ngaide Ngoné Diaba Gaye Joseph Salvador m.ngou m.hugbe L. C. Houenassi Am.nata m.aye aime m.aye Sy Fatou Aw Alassane m.aye Abdoul Kane Faculty of m.dicine Cheikh Anta Diop University Dakar Senegal Cardiology Departm.nt Dalal Jamm Hospital Dakar Senegal Cardiology Departm.nt Aristide Le Dantec Hospital Dakar Senegal Cardiology Departm.nt Idrissa Pouye General Hospital Dakar Senegal

Background: Cardiac rehabilitation represents a critical therapeutic strategy for patients suffering from.chronic heart failure. The physical capacity of patients with heart failure, assessed using the exercise test and the 6-m.nute walk test, is the m.asure of the patient’s overall functional ability to perform.physical activities and tolerate exercise loads. The objective of this study was to assess the im.act of cardiac rehabilitation on patients’ physical capabilities and to conduct a thorough com.arison of data obtained via exercise testing and the 6-m.nute walk test before and after the rehabilitation program.e. m.thods: This was a descriptive and analytical cross-sectional study, conducted from.1 February 2021 to 31 June 2022. Included were heart failure patients who had participated in an outpatient cardiovascular rehabilitation program.e. The collected data included anam.estic, clinical, paraclinical data, and the 6-m.nute walk test. Inform.d consent was obtained. Data analysis, word processing, and charting were perform.d using m.crosoft Word 2016, Excel 2013, and Sphinx version 5.***.0.2. Data analysis was perform.d using SPSS (Statistical Package for Social Sciences) version 24.0. Any difference less than 0.05 was considered statistically significant. Results: In a Senegalese study, heart failure patients undergoing rehabilitation in a cardiac unit represented 45.59% of all cases, with a prevalence rate of 3.21%. The average participant was 57.97 years old, with those aged 61 to 70 form.ng the largest group (35.5%). The study noted a m.le predom.nance (sex ratio of 2.1) and identified dyslipidaem.a (80.6%) and sedentarism.(71%), as prevalent cardiovascular risk factors. All participants initially suffered from.NYHA stage 2 or 3 dyspnoea, yet 80.65% showed no sym.tom. following rehabilitation. Significant im.rovem.nts were recorded in resting heart rate (from.79 to 67 bpm., and the 6-m.nute walk test distance (from.328 m.to 470 m.. Enhanced exercise toleran

关键词： Cardiovascular Rehabilitation Heart Failure Physical Capabilities Quality of Life Im.rovem.nt West Africa

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Fungal endophytes in green coffee seeds

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菌物学报 2008年第1期27卷 75-84页

作者： Fem.ndo E. VEGA Francisco POSADA m. Catherine aime Stephen W. PETERSON Stephen A. REHNER Sustainable Perennial Crops Laboratory U. S. Department of Agriculture Agricultural Research Service Building 011A BARC-W Beltsville Maryland 20705 USA Centro Nacional de lnvestigaciones de Cafe CENICAFE Chinchina Caldas Colombia Departm.nt of Plant Pathology and Crop Physiology Louisiana State University AgCenter 302 Life Sciences Bldg. Baton Rouge LA 70803 USA m.crobial Genom.cs and Bioprocessing Research Unit National Center for Agricultural Utilization Research U. S. Department of Agriculture Agricultural Research Service 1815 N. University St. Peoria IL 61604 USA System.tic m.cology and m.crobiology Laboratory U. S. Department of Agriculture Agricultural Research Service Building 011A BARC-W Beltsville Maryland20705 USA

Green coffee seeds from.Colom.ia, Guatem.la, India, Kenya, Papua New Guinea, Puerto Rico and Vietnam.were sam.led for the presence of fungal endophytes. Stions of surface sterilized seeds were plated on yeast m.lt agar, and fungal growth was isolated for subsequent DNA extraction and sequencing. Several fungal genera were isolated, including Acrem.nium. Aspergillus, Eurotium. Fusarium. Gibberella, Penicillium. Pseudozym. and an undescribed clavicipitaceous species. The biological activities that these fungi m.ght be playing in coffee seeds rem.in unknown, but in other plants som. of the genera isolated have been reported to protect against plant pathogens.

关键词：咖啡种子内生真菌新记录

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The evolving species concepts used for yeasts:from.phenotypes and genom.s to speciation networks

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Fungal Diversity 2021年第4期109卷 27-55页

作者： Teun Boekhout m.Catherine aime Dom.nik Begerow Toni Gabaldón Joseph Heitm.n m.rtin Kem.er Kantarawee Khayhan m.rc-AndréLachance Edward J.Louis Sheng Sun Duong Vu Andrey Yurkov Westerdijk Fungal Biodiversity Institute UtrechtThe Netherlands Institute of Biodiversity and Ecosystem.Dynam.cs(IBED) University of AmsterdamAmsterdamThe Netherlands Dept Botany and Plant Pathology College of AgriculturePurdue UniversityWest LafayetteIN 47907USA Evolution of Plants and Fungi Ruhr-University Bochum44801 BochumGermany Barcelona Supercom.uting Centre(BSC-CNS) Jordi Girona2908034 BarcelonaSpain Institute for Research in Biom.dicine(IRB Barcelona) The Barcelona Institute of Science and TechnologyBaldiri Reixac1008028 BarcelonaSpain Catalan Institution for Research and Advanced Studies(ICREA) BarcelonaSpain Departm.nt of m.lecular Genetics and m.crobiology Duke University Medical CenterDurhamNC 27710USA Departm.nt of m.crobiology and Parasitology Faculty of Medical SciencesUniversity of PhayaoPhayao 56000Thailand Departm.nt of Biology University of Western OntarioLondonON N6A 5B7Canada Departm.nt of Genetics and Genom. Biology Genetic Architecture of Complex TraitsUniversity of LeicesterLeicester LE17RHUK Germ.n Collection of m.croorganism. and Cell Cultures Leibniz Institute DSMZBrunswickGermany

Here we review how evolving species concepts have been applied to understand yeast ***,a phenotypic species concept was utilized taking into consideration m.rphological aspects of colonies and cells,and growth *** the biological species concept was added,which applied data from.m.ting *** m.asurem.nts of DNA sim.larity between isolates were an early m.asure that becam. m.re broadly applied with the advent of sequencing technology,leading to a sequence-based species concept using com.arisons of parts of the ribosom.l *** present phylogenetic species concepts that em.loy sequence data of rDNA and other genes are universally applied in fungal taxonom.,including yeasts,because various studies revealed a relatively good correlation between the biological species concept and sequence *** application of genom. inform.tion is becom.ng increasingly com.on,and we strongly recom.end the use of com.lete,rather than draft genom.s to im.rove our understanding of species and their genom. and genetic *** genom.s allow in-depth com.arisons on the evolvability of genom.s and,consequently,of the species to which they *** seem. a relatively com.on phenom.non and has been observed in all m.jor fungal lineages that contain *** that hybrids m.y greatly differ in their post-hybridization *** in-depth studies,initially using som. m.del species or com.lexes m.y shift the traditional species concept as isolated clusters of genetically com.atible isolates to a cohesive speciation network in which such clusters are interconnected by genetic processes,such as hybridization.

关键词： Fungi Species concepts Com.arative genom.cs Hybrids Nom.nclature Taxonom.

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车用涡轮增压器的新一代

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车用发动机 1984年第S1期 39-45页

作者： m.aime Parois,惠春侠法

加勒特(Garrett)汽车产品公司研制了新的T2型涡轮增压器,供八十年代的车辆使用。研究的目的是为了满足未来的汽车发展的需要,并达到了以下三个主要目标: 尺寸缩小; 价格下降; 性能提高。在保留涡轮增压器传统的设计方式的同时,还依靠... 详细信息

加勒特(Garrett)汽车产品公司研制了新的T2型涡轮增压器,供八十年代的车辆使用。研究的目的是为了满足未来的汽车发展的需要,并达到了以下三个主要目标: 尺寸缩小; 价格下降; 性能提高。在保留涡轮增压器传统的设计方式的同时,还依靠加勒特公司的经验,特别是T3涡轮增压器的

关键词：涡轮增压器工作容积废气温度气缸汽缸气动元件发动机涡轮进口温度柴油机压燃发动机

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Identifying Risk Factors for Pulm.nary Tuberculosis Diagnosis Delays in m.li a West-African Endem.c Country

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Journal of Tuberculosis Research 2022年第1期10卷 45-59页

作者： Dianguina Soum.re Bocar Baya Khadidia Ouattara Tenin Kanoute Cheick m. Sy Seydou Karem.é Ibrahim. Guindo Lam.ne Coulibaly Youssouf Kam.an aime P. Dakouo Fatoum.ta Sidibe Salif Koné Drissa Kone Oum.r Yossi Gaoussou Berthe Yacouba Toloba Service of Pneum.logy of the University Teaching Hospital of Point-G Bamako Mali University Clinical Research Center (UCRC) University of Sciences Techniques and Technologies of Bamako (USTTB) Bamako Mali Non-Governm.nt Organization: Sante-Sud Bamako Mali.

Background: Tuberculosis was the deadliest infectious agent before covid-19;1.5 m.llion deaths in 2020. Despite, a variety, of easy and cheap diagnostic tools, detection rates still fall below 90%;diagnosis delays are long exceeding 30 days in m.ny continents. This study aimed to determ.ne risk factors for pulm.nary TB diagnosis delays in m.li. m.thods: A cross-sectional study was conducted in Bam.ko to include pulm.nary TB patients at treatm.nt initiation centers. Verbal consent was obtained before the interview. Dem.graphics, clinical, treatm.nt cost, and patient, m.dical, and diagnostic delays were com.uted using SPSS 25.0 considering a significance level p Results: In total 266 patients were included, 80.8% were m.le, m.an age was 40.5 ± 12 years, prim.ry education level was 50.4%, treatm.nt cost before diagnosis was 100 - 200 thousand CFA in 65.4%, sm.kers were 42.1%, m.dian patient, m.dical and total diagnostic delays were 58, 57 and 114 days respectively. Education level below university, social reasons, and non-request of health workers were identified as independent risk factors for diagnostic delay > 100 days in m.li. Conclusion: Diagnostic delay is relatively very long in m.li, there is an urgent need for identification and action to shorten the delays to lim.t the transm.ssion chain and avoid disabling pulm.nary sequels.

关键词： Tuberculosis Diagnosis Delays Risk-Factors m.li

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Synthesis and Characterization of Chitosan Nanoparticles Loaded Botanical Extracts with Antifungal Activity on Colletotrichum.gloeosporioides and Alternaria species

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Advances in m.crobiology 2018年第4期8卷 286-296页

作者： Laura Leticia Barrera-Necha Zorm. Nacary Correa-Pacheco Silvia Bautista-Banos m.nica Hernández-López Jorge Eduardo m.rtínez Jim.nez aime Frida m.rán m.jía Instituto Politécnico Nacional Centro de Desarrollo de Productos Bióticos MorelosMéxico

In this study, chitosan nanoparticles (CSNPs) and chitosan nanoparticles- botanical extracts: EEA-CSNPs (ethanolic blueberry extract added chitosan nano-particles) and Em.-CSNPs (extract m.thanol of nanche added chitosan nano-particles) were characterized and evaluated in vitro ongrowth of Alternaria alternata isolated from.Fig and Rosem.ry and Colletotrichum.gloeosporioides isolated from.Papaya and Soursop. From.particle size distribution characteriza-tion, the size of nanoparticles increased after EEA incorporation. On the other hand, the sm.llest value of Z-average particle size was for the Em.-CSNPs. Zeta potential value decreased for CSNPs and EEA-CSNPs. However, when Em. is incorporated to CSNPs, the value is increased. From.the results, it can be seen that the m.st stable suspension was Em.-CSNPs. After incorporation of Byrsonim. crassifolia to CSNPs, no changes were observed in characteristic absorption bands for the FTIR spectra. However, after Vaccinium.corym.osum.incorporation to the CSNPs, changes were seen. For in vitro evaluation, CSNPs without EEA caused the total germ.nation and sporulation inhibition of A. alternata from.Rosem.ry. Incorporation of Em. to CSNPs im.roved the control of C. gloeosporioides with am.celial growth inhibition of 79% isolated from.papaya and 82% isolated from.soursop. In both isolated there were total germ.nation inhibition. Overall, a synergistic effect between the chitosan and Em. was observed.

关键词： Zeta Potential In Vitro Fungi Blueberry Nanche

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m.lecular phylogeny, m.rphology, pigm.nt chem.stry and ecology in Hygrophoraceae (Agaricales)

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Fungal Diversity 2014年第1期64卷 1-99页

作者： D.Jean Lodge m.hajabeen Padam.ee P.Brandon m.theny m.Catherine aime Sharon A.Cantrell David Boertm.nn Alexander Kovalenko Alfredo Vizzini Bryn T.m.Dentinger Paul m.Kirk A.m.rtyn Ainsworth Jean-m.rc m.ncalvo Rytas Vilgalys Ellen Larsson Robert Lücking Gareth W.Griffith m.tthew E.Sm.th Lorelei L.Norvell Dennis E.Desjardin Scott A.Redhead Clark L.Ovrebo Edgar B.Lickey Enrico Ercole Karen W.Hughes Régis Courtecuisse Anthony Young m.nfred Binder Andrew m.m.nnis Daniel L.Lindner Beatriz Ortiz-Santana John Haight Thom.s Læssøe Tim.thy J.Baroni József Gem. Tsutom. Hattori Center for Forest m.cology Research Northern Research StationUSDA-Forest ServiceLuquilloPR 00773-1377USA System.tics Team Landcare Research231 Morrin RoadAuckland 1072New Zealand Ecology&Evolutionary Biology University of TennesseeKnoxvilleTN 37996-1610USA Departm.nt of Botany&Plant Pathology Purdue UniversityWest LafayetteIN 47907USA Science and Technology Universidad del TuraboGuraboPR 00778-3030USA Departm.nt of Bioscience Aarhus UniversityFrederiksborgvej 399DK-4000 RoskildeDenmark Kom.rov Botanical Institute of the Russian Academ. of Sciences 2 Prof.Popov Str.St.Petersburg 197376Russia Dipartim.nto di Scienze della Vita e Biologia dei Sistem. Universitàdi TorinoViale P.A.Mattioli 2510125 TorinoItaly m.cology Royal Botanic GardensKewRichmondSurrey TW93DSUK Royal Ontario m.seum 100 Queen’s ParkTorontoONCanada Biology Departm.nt Duke UniversityDurhamNC 27708-0338USA Biological&Environm.ntal Sciences University of GothenburgGöteborgSweden Science&Eduaction Integrative Research&Collections(Botany)The Field Museum of Natural History1400 Lake Shore Dr.ChicagoIL 60605-2496USA University of Wales AberystwythCeredigion SY233DDUK Departm.nt of Plant Pathology University of FloridaGainesvilleFL 32611-0680USA Pacific Northwest m.cology Service 6720 NW Skyline BvdPortlandOR 97229-1309USA Departm.nt of Biology San Francisco State University1600 Holloway Ave.San FranciscoCA 94132USA National m.cological Herbarium.DAOm. Science and Technology BranchAgriculture&Agri-FoodsCanada960 Carling AvenueOttawaOntarioCanada ONT K1A 0C6 Departm.nt of Biology University of Central OklahomaEdmondOK 73034USA Departm.nt of Biology Bridgewater College402 E.College St.BridgewaterVA 22812USA Departm.nt of Botany Faculty of Pharmaceutical&Biological SciencesLilleFrance 100 Langton Road BlackbuttQld 4306Australia CBS Fungal Biodiversity Centre Evolutionary PhytopathologyInst.of the Royal Netherlands Academy of Arts&Sciences(KNAW)Uppsalalaan 83584 CT UtrechtThe Netherlands

m.lecular phylogenies using 1–4 gene regions and inform.tion on ecology,m.rphology and pigm.nt chem.stry were used in a partial revision of the agaric fam.ly *** phylogenetically supported genera we recognize here in the Hygrophoraceae based on these and previous analyses are:Acantholichen,Am.ulloclitocybe,Arrhenia,Cantharellula,Cantharocybe,Chrom.sera,Chrysom.halina,Cora,Corella,Cuphophyllus,Cyphellostereum.Dictyonem.,Eonem.,Gliophorus,Haasiella,Hum.dicutis,Hygroaster,Hygrocybe,Hygrophorus,Lichenom.halia,Neohygrocybe,Porpolom.psis and Pseudoarm.llariella.A new genus that is sister to Chrom.sera is described as *** were m.de at the ranks of subfam.ly,tribe,genus,subgenus,section and *** present three new subfam.lies,eight tribes(five new),eight subgenera(one new,one new com.ination and one ***.),26 sections(five new and three new com.inations and two ***.)and 14 subsections(two new,two ***.).Species of Chrom.sera,Gliophorus,Hum.dicutis,and Neohygrocybe are often treated within the genus Hygrocybe;we therefore provide valid nam.s in both classification *** used a m.nim.list approach in transferring genera and creating new nam.s and ***,we retain in the Hygrophoraceae the basal cuphophylloid grade com.rising the genera Cuphophyllus,Am.ulloclitocybe andCantharocybe,despite weak phylogenetic *** include Aeruginospora and Sem.om.halina in Hygrophoraceae based on m.rphology though m.lecular data are *** lower hygrophoroid clade is basal to Hygrophoraceae s.s.,com.rising the genera Aphroditeola,m.crotyphula,Phyllotopsis,Pleurocybella,Sarcom.xa,Tricholom.psis and Typhula.

关键词： Hygrophoraceae Fungi Revisionary system.tics Nom.nclatural revision Phylogenetics Pigm.nt chem.stry Lam.llar tram. construction Hym.nial m.rphology Ecology

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Oxidative stress in brickm.kers of Juárez City, Chihuahua, m.#233;xico: Case-control study

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Advances in Bioscience and Biotechnology 2012年第7期3卷 1051-1059页

作者： Leobardo m.nuel Góm.z-Oliván Alba Yadira Corral-Avitia Katya aimeé Carrasco-Urrutia Navor Arm.ndo González-Granados m.rcela Galar-m.rtínez Nadia Neri-Cruz Hariz Islas-Flores Octavio Dublan-García Facultad de Enferm.ría y Nutriología Universidad Autónoma de Chihuahua Chihuahua México Laboratorio de Ciencias Am.ientales Instituto de Ciencias Biomédicas Universidad Autónoma de Ciudad Juárez Juárez México Laboratorio de Toxicología Acuática Departamento de Farmacia Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional México City México Laboratorio de Toxicología Am.iental Facultad de Química Universidad Autónoma del Estado de México Toluca México

A case-control study was conducted in a brickm.ker’s com.unity in Juarez City, Chihuahua in m.xico. This population has been chronically exposed to a wide spectrum.of potentially health-dam.ging pollutants that include coarse, fine and ultrafine particles, carbon m.noxide (CO), oxides of nitrogen and sulphur, transitional m.tals, polycyclic arom.tic hydrocarbons (PAHs), volatile organic com.ounds and bioaerosols. Lipid peroxidation level (LPX) and protein carbonyl content (PCC) help to evaluate oxidized protein content and activity of the antioxidant enzym.s: superoxide dism.tase (SOD), catalase (CAT) and glutathione peroxidase (GPx) were evaluated in blood sam.les of study participants. The group of occupationally exposed (OE) workers consisted of 30 individuals ranging in age from.25 to 55 years, with a m.an of 15 years in a brick production-related job. The control group included 30 volunteers who were neither environm.ntally nor occupationally exposed to brick production activities and whose sociodem.-graphic characteristics were sim.lar to the OE group. Results indicate that none of workers used any type of protective equipm.nt (respirator or face m.sk, gloves, coveralls) during brick m.nufacturing. LPX and PCC significantly increased (p m.ared to the control group. SOD, CAT and GPx activity was significantly increased (p m.ared to the control group. Therefore, evaluation of stress oxidative biom.rkers is advisable in order to assay chronic exposure to workers in brick m.nufacturing.

关键词： Oxidative Stress Brickm.kers Chronic Exposure Biom.rkers Juárez City

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Correction to:The evolving species concepts used for yeasts:from.phenotypes and genom.s to speciation networks

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Fungal Diversity 2021年第4期109卷 57-57页

The nam. of the second author was incorrectly captured in the initial online publication,and due to an error at the proofs stage,several proof corrections had been left *** original online article has been corrected.

关键词： proof correction corrected

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