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China CDC weekly 2024年第13期6卷 261-266,I0005,I0006页

作者： Junhua Huang Wei Zheng aili wang Weiling Han Junxi Chen Hang An Lailai Yan Zhiwen Li Guanghui Li Division of Endocrinology and Metabolism Department of ObstetricsBeijing Obstetrics and Gynecology HospitalCapital Medical University.Beijing Maternal and Child Health Care HospitalBeijingChina Department of Obstetrics and Gynecology Beijing Luhe HospitalCapital Medical UniversityBeijingChina Institute of Reproductive and Child Health National Health Commission Key Laboratory of Reproductive HealthPeking UniversityBeijingChina Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Department of Laboratorial Science and Technology School of Public HealthPeking UniversityBeijingChina

What is already known about this topic?The level of molybdenum(Mo)in a mother’s urine has been linked to the growth rate of the fetus and the blood pressure levels in *** is added by this report?We evaluated the variations in maternal plasma Mo concentrations throughout pregnancy and their potential association with the risk of spontaneous preterm birth(SPB).What are the implications for public health practice?Future research must determine the Mo levels in pregnant women across various regions in ***,particular attention needs to be given to the potential increase in Mo concentration throughout pregnancy and its possible adverse impacts on the health of both the mother and the fetus.

关键词： mother urine pregnancy

Transferrin Is Up-Regulated by Microbes and Acts as a Negative Regulator of Immunity to Induce Intestinal Immunotolerance

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Research 2024年第3期7卷 761-774页

作者： Xiaopeng Tang Mingqian Fang Ruomei Cheng Junkun Niu Xiaoshan Huang Kuanhong Xu Gan wang Yang Sun Zhiyi Liao Zhiye Zhang James Mwangi Qiumin Lu aili wang Longbao Lv Chao Liu Yinglei Miao Ren Lai Engineering Laboratory of Peptides of Chinese Academy of Sciences Key Laboratory of Bioactive Peptides of Yunnan ProvinceKIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesNational Resource Center for Non-Human PrimatesNational Research Facility for Phenotypic&Genetic Analysis of Model Animals(Primate Facility)and Sino-African Joint Research CenterNew Cornerstone Science InstituteKunming Institute of Zoologythe Chinese Academy of SciencesNo.17 Longxin RoadKunmingYunnan650201China School of Basic Medicine Qingdao UniversityQingdao 266071ShandongChina. Department of Gastroenterology First Affiliated Hospital of Kunming Medical UniversityYunnan Institute of Digestive DiseaseKunming 650032YunnanChina Yunnan Province Clinical Research Center for Digestive Diseases Kunming 650032YunnanChina Kunming College of Life Science University of Chinese Academy of SciencesKunming 650204YunnanChina Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences University of Science and Technology of ChinaHefei 230027AnhuiChina Center for Evolution and Conservation Biology Southern Marine Science and Engineering Guangdong LaboratoryGuangzhou 511458GuangdongChina.

Cross-talks (e.g., host-driven iron withdrawal and microbial iron uptake between host gastrointestinal tract and commensal microbes) regulate immunotolerance and intestinal homeostasis. However, underlying mechanisms that regulate the cross-talks remain poorly understood. Here, we show that bacterial products up-regulate iron-transporter transferrin and transferrin acts as an immunosuppressor by interacting with cluster of differentiation 14 (CD14) to inhibit pattern recognition receptor (PRR) signaling and induce host immunotolerance. Decreased intestinal transferrin is found in germ-free mice and human patients with ulcerative colitis, which are characterized by impaired intestinal immunotolerance. Intestinal transferrin and host immunotolerance are returned to normal when germ-free mice get normal microbial commensalism, suggesting an association between microbial commensalism, transferrin, and host immunotolerance. Mouse colitis models show that transferrin shortage impairs host’s tolerogenic responses, while its supplementation promotes immunotolerance. Designed peptide blocking transferrin–CD14 interaction inhibits immunosuppressive effects of transferrin. In monkeys with idiopathic chronic diarrhea, transferrin shows comparable or even better therapeutic effects than hydrocortisone. Our findings reveal that by up-regulating host transferrin to silence PRR signaling, commensal bacteria counteract immune activation induced by themselves to shape host immunity and contribute for intestinal tolerance.

关键词： impaired immunity tolerance

Effect of frequent blood pressure measurements after discharge on clinical outcomes in ischemic stroke patients

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Chinese Medical Journal 2024年第13期137卷 1629-1631页

作者： Ruirui wang Yanni Wu Mengyao Shi Pinni Yang Yang Liu Yang Jiao Yanbo Peng aili wang Tan Xu Jing Chen Yonghong Zhang Jiang He Department of Epidemiology School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric DiseasesSuzhou Medical College of Soochow UniversitySuzhouJiangsu 215123China Department of Cardiology Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215004China Department of Epidemiology Tulane University School of Public Health and Tropical MedicineNew OrleansLA 70112USA Department of Cardiology First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215129China Department of Neurology Affiliated Hospital of North China University of Science and TechnologyTangshanHebei 063000China Department of Medicine Tulane University School of MedicineNew OrleansLA 70112USA

To the Editor:Stroke is a major cause of death and longterm serious disability in adults *** is the most important modifiable risk factor for primary and secondary prevention of stroke.[1]Even a modest reduction in clinical blood pressure(BP)of approximately 10/5 mmHg is associated with a significant 30%risk reduction of adverse clinical *** clinical evidence strongly advocated the effectiveness of managing BP to reduce adverse outcomes after ischemic stroke,[2]the management and control of BP in ischemic stroke patients after discharge remain poor.

关键词： prevention death after

病毒携带人群影响手足口病传播的数学模型及动力学分析

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武汉大学学报（理学版） 2024年第4期70卷 526-538页

作者：白朵贺静敏王爱丽宝鸡文理学院数学与信息科学学院陕西宝鸡721013 西安理工大学理学院陕西西安710054

建立了一类具有周期传染率的手足口病模型,研究病毒携带者对疾病传播的影响。定义了模型的基本再生数R 0,分析了模型无病平衡态的全局稳定性和正周期解的存在性。结果表明,当R 01时,疾病演变为地方病并呈现周期性变化。应用实际数据对... 详细信息

建立了一类具有周期传染率的手足口病模型,研究病毒携带者对疾病传播的影响。定义了模型的基本再生数R 0,分析了模型无病平衡态的全局稳定性和正周期解的存在性。结果表明,当R 01时,疾病演变为地方病并呈现周期性变化。应用实际数据对模型参数进行了估计,并给出R 0的估计值为2.3286。关键参数的敏感性分析表明,降低病毒携带者的传染性、加强高危人群的手部消毒和日常清洁、增强公众对手足口病的重视程度、加强自我干预措施的实施,均可有效遏制手足口病的传播。

关键词：手足口病病毒携带者基本再生数全局动力学敏感性分析

Evolution of copper nanowires through coalescing of copper nanoparticles induced by aliphatic amines and their electrical conductivities in polyester films

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Chinese Journal of Chemical Engineering 2022年第4期35卷 284-291页

作者： Mingxia Tian aili wang Hengbo Yin Faculty of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China

Copper nanowires were synthesized by the wet chemical reduction method using copper sulfate as the copper precursor,aliphatic amines(methylamine,ethanediamine,1,2-propanediamine)as the inducing reagents,and hydrazine hydrate as the reductant through the aging and reduction *** high-resolution transmission electron microscopy(HRTEM)images reveal that the copper nanowires were synthesized by coalescing extremely small-sized copper nanoparticles with the particle sizes of1–6 nm in copper complex micelles.A longer aging time period favored the coalescing of the copper nanoparticles to form thinner copper nanowires in the following reduction *** coalescing extent of copper nanoparticles in copper nanowires was highly enhanced by ethanediamine and 1,2-propanediamine as compared with that by *** copper nanowire-filled polyester films had higher electrical conductivity than the copper nanoparticle-filled ones.

关键词： Nanomaterials Nanostructure Electronic materials Copper nanowires Electrical conductivity Polyester film

CNN-Transformer结合对比学习的高光谱与LiDAR数据协同分类

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光学精密工程 2024年第7期32卷 1087-1100页

作者：吴海滨戴诗语王爱丽岩堀祐之于效宇哈尔滨理工大学测控技术与通信工程学院黑龙江省激光光谱技术及应用重点实验室黑龙江哈尔滨150080 中部大学计算机科学学院日本爱知487-8501 电子科技大学中山学院电子信息学院广东中山528400

针对高光谱图像(hyperspectral images,HSI)与LiDAR数据多模态分类任务中的跨模态信息表达和特征对齐等问题,提出一种基于对比学习CNN-Transformer高光谱和LiDAR数据协同分类网络(Contrastive Learning based CNNTransformer Network,CLCT-Net)。CLCT-Net通过由ConvNeXt V2 Block构成的共有特征提取模块,获得不同模态间的共性特征,解决异构传感器数据之间语义对齐的问题。构建了包含空间-通道分支和光谱上下文分支的双分支HSI编码器,以及结合频域自注意力机制的LiDAR编码器,以获取更丰富的特征表示。利用集成对比学习进行分类,进一步提升多模态数据协同分类的精度。在Houston 2013和Trento数据集上的实验结果表明,相较于其他高光谱图像和Li‐DAR数据分类模型,本文所提模型获得了更高的地物分类精度,分别达到了92.01%和98.90%,实现了跨模态数据特征的深度挖掘和协同提取。

关键词：高光谱图像激光雷达数据 Transformer 卷积神经网络对比学习

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Interaction between Pd and Cu nanoparticles in bimetallic CuPdx nanoparticles and its impact on oxidation of 1,2-propanediol to aliphatic acids

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Chinese Journal of Chemical Engineering 2020年第4期28卷 1085-1094页

作者： Wei Tao aili wang Hengbo Yin Faculty of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212000China

Bimetallic CuPdx nanoparticles synthesized by the wet chemical reduction method were used as the catalysts in the catalytic oxidation of 1,2-propanediol with gaseous oxygen to aliphatic *** palladium and copper nanoparticles in the bimetallic CuP dxnanoparticles had an alloying *** catalytic activity of the palladium nanoparticles in the bimetallic CuP dxnanoparticles was enhanced by the interaction between the palladium and copper *** the bimetallic CuPd7 nanoparticles catalyzed the oxidation of 1,2-propanediol in an alkaline aqueous solution at 100℃for 3h,lactic,formic,and acetic acids were dominantly produced with the total selectivity of above 99%at the 1,2-propanediol conversion of 85.9%.The simulation of the reaction kinetic equation on the CuPd7 catalyst showed that the reaction activation energy was 29.4kJ·mol^-1,indicating that the bimetallic CuPd7 nanoparticles had a high catalytic activity in the oxidation reaction between 1,2-propanediol and gaseous oxygen.

关键词： Bimetallic CuPdx nanoparticles 1,2-Propanediol Aliphatic acids

Preparation of graphite nanosheets in different solvents by sand milling and their enhancement on tribological properties of lithium-based grease

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Chinese Journal of Chemical Engineering 2020年第4期28卷 1177-1186页

作者： Jin Zhang aili wang Hengbo Yin Faculty of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China

Graphite nanosheets with the average thicknesses ranging from 24.4 to 48.9 nm were prepared with the use of expanded graphite as the raw material by sand milling in deionized water,anhydrous ethanol,glycerol,and 1,4-butanediol,*** ethanol favored the formation of graphite nanosheets with a smaller average *** the graphite nanosheets with the content of 2 wt%were added in lithium-based grease,the average friction coefficient decreased by 27%as compared with the pure lithium-based *** weld point and load wear index were 1.6 and 1.4 times those of the pure lithium-based grease,*** tribological properties of the graphite nanosheet-containing lithium-based grease were comparable with those of the graphene-containing lithium-based grease.

关键词： Graphite nanosheets Expanded graphite Lithium-based grease Tribological property

基于空间金字塔注意力机制残差网络的高光谱图像分类

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液晶与显示 2024年第6期39卷 833-843页

作者：刘和宋璎珞胡龙湘刘国辉王侃王爱丽国网黑龙江省电力有限公司综合信息中心黑龙江哈尔滨150010 哈尔滨理工大学测控技术与通信工程学院黑龙江省激光光谱技术及应用重点实验室黑龙江哈尔滨150080

为了提取高光谱图像的空间-光谱联合特征,本文提出了一种基于改进的空间金字塔注意力机制残差网络的高光谱图像分类模型。首先采用主成分分析法去除光谱冗余,结合空间金字塔注意力机制,改进残差网络的高光谱图像分类模型获取精细化特征... 详细信息

为了提取高光谱图像的空间-光谱联合特征,本文提出了一种基于改进的空间金字塔注意力机制残差网络的高光谱图像分类模型。首先采用主成分分析法去除光谱冗余,结合空间金字塔注意力机制,改进残差网络的高光谱图像分类模型获取精细化特征。然后利用空间金字塔注意力模型实现多尺度联合特征关注,提升对联合特征的敏感性,并有效地强调并聚焦空间和光谱信息,实现信息交互。最后经过Softmax分类器获得分类标签。本文提出的方法在MUUFL和Tento数据集上进行了实验,结果表明,本文算法的总体分类精度分别达到了94.08%和98.32%。相比于其他高光谱分类模型,本文模型的收敛速度较快,在分类性能上取得了明显的提升,获得了更高的地物分类精度。

关键词：高光谱图像分类注意力机制空间-光谱特征

“健脾益气养血止痛”法治疗乳腺癌骨转移患者的临床研究

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肿瘤防治研究 2024年第4期51卷 259-264页

作者：孙颖李志明康宁王文雯王爱丽李仝北京中医药大学第三附属医院肿瘤血液科北京100029

目的探讨“健脾益气养血止痛”法治疗乳腺癌骨转移患者的疗效及改善疼痛症状的临床效果。方法纳入80例乳腺癌骨转移患者临床资料,将其按照数字表法随机分为观察组与对照组。对照组使用唑来膦酸治疗,观察组以对照组为基础,应用自拟健脾... 详细信息

目的探讨“健脾益气养血止痛”法治疗乳腺癌骨转移患者的疗效及改善疼痛症状的临床效果。方法纳入80例乳腺癌骨转移患者临床资料,将其按照数字表法随机分为观察组与对照组。对照组使用唑来膦酸治疗,观察组以对照组为基础,应用自拟健脾益气养血止痛方口服治疗。对比不同治疗方案对患者疼痛症状、体力状况、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)、C反应蛋白(CRP)和生活质量的影响。结果治疗前两组患者疼痛评分、体力状况评分、CRP、IL-6、TNF-α水平、睡眠和生活质量评分均无明显差异(均P>0.05),治疗后1、2、4个月时两组患者疼痛评分均下降,且观察组低于对照组(P<0.05),观察组患者疼痛总缓解率高于对照组(P<0.05);治疗后两组患者CRP、IL-6、TNF-α水平和睡眠质量评分均下降,且观察组低于对照组(P<0.05);治疗后两组体力状况和生活质量评分均提高,且观察组高于对照组(P<0.05)。结论乳腺癌骨转移患者以健脾益气养血止痛方口服治疗效果显著,可明显改善疼痛症状,并改善患者睡眠质量与生活质量,降低CRP、IL-6、TNF-α水平。

关键词：乳腺癌骨转移中药治疗疼痛生活质量

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