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干旱区研究 2023年第9期40卷 1369-1381页

作者：陈爱军张寅楚志刚南京信息工程大学气象灾害教育部重点实验室江苏南京210044 南京信息工程大学中国气象局气溶胶与云降水重点开放实验室江苏南京210044 南京信息工程大学大气物理学院江苏南京210044

FY-4A定量降水估计产品(Quantitative PrecipitationEstimation,QPE)为深入研究中亚五国降水的时空分布特征提供了数据源。本文首先采用全球降水观测(Global PrecipitationMeasurement,GPM)多星集成降水终级产品IMERG-F(Integrated Multi-satellite RetrievalsforGPM Final run)评估FY-4A QPE,然后利用FY-4A QPE分析中亚五国的降水特点及时空分布特征,结果表明:(1)FY-4A QPE能够精细地反映中亚五国降水的空间分布差异,降水估计结果比较合理且与IMERG-F的时序变化具有较好的一致性。(2)中亚五国年平均降水量的空间分布差异大,且与海拔高度有关,高海拔地区的年平均降水量超过500 mm,但面积占比不足10%;低海拔地区的年平均降水量不足350 mm,但面积占比却超过90%。(3)中亚五国降水的空间分布有明显的季节性,夏季降水范围最广,平均降水量超过50 mm;秋季平均降水量最小,绝大部分地区平均降水量不足40 mm。吉尔吉斯斯坦和塔吉克斯坦四季降水相对充足,部分区域季节平均降水量超过480 mm;哈萨克斯坦中西部、乌兹别克斯坦中西部和土库曼斯坦北部季节平均降水量不足40 mm。(4)根据月平均降水量超过40 mm区域的聚集度,中亚五国月平均降水的空间分布可以大致分为点状离散分布型、干旱型、半干半湿型和三明治型四种分布形态。(5)中亚五国夏季降水多发区的逐小时平均降水量具有“准三小时”周期性日变化特征,午后至前半夜是降水多发时段之一,降水类型以小雨为主,其次是少量的中雨。

关键词： FY-4A 定量降水估计中亚时空分布特征

Sperm CFTR expression rate shows potential predictive capacity of fecundity in healthy population

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Sperm CFTR expression rate shows potential predictive capaci...

作者： Peibei Sun Huiming Xu Kun Li Hongchao Li aijun chen Meijun chen Haitao Dai Ya Ni Department of Reproductive Physiology Zhejiang Academy of Medical Sciences Department of Andrology Zhejiang Family Planning Research Institute Centre for Reproductive Medicine Zhejiang Academy of Medical Sciences

Cystic fibrosis transmembrane conductance regulator(CFTR) is a cAMP activated chloride ion channel which expressed in human epithelial cells in a variety of *** previous studies showed that CFTR is also expressed in the equatorial segment of human sperm and involved in sperm capacitation and sperm *** sperm quality is always considered as an indicator for fecundity,World Health Organization(WHO) has provided reference values for semen parameters which reflect sperm *** the reference values sometimes lead to *** approaches should be found to improve the *** this study,135 healthy couples were divided into two groups according to their fertility during five years follow-up ***-tailed independent samples t test showed that sperm CFTR expression rate of fertile group was significantly higher than that of infertile *** regression model also showed that fertility improved with the increasing of sperm CFTR expression *** value for fecundity prediction by sperm CFTR expression rate was calculated with receiver operating characteristic(ROC)curve,and the value was at 43.75%based on Youden *** then divided the 135 couples into two groups according to the threshold ***-Meier survival curve analysis showed that cumulative pregnancy rate(CPR) of the couples with sperm CFTR expression rate greater than 43.75%was significantly larger than others,while mean time to pregnancy(TTP) of the group was much ***,sperm CFTR expression rate may be potential indicator for fecundity prediction in health couples.

关键词： cystic fibrosis transmembrane conductance regulator fecundity human sperm

来源： cnki会议评论

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Metadata共享体系的实现模型

清华大学学报（自然科学版） 1999年第12期39卷 90-93页

作者：赵永平过静君陈爱军清华大学土木工程系北京100084 北京大学遥感与GIS研究所北京100871

通过对地理信息标准化发展趋势的分析，认为Ｍｅｔａｄａｔａ是地理信息共享的关键技术，并根据Ｍｅｔａｄａｔａ的层次关系，提出了实现Ｍｅｔａｄａｔａ体系的基本模型。结合该模型，作者在Ｍｅｔａｄａｔａ标准草案的基础上，研制... 详细信息

通过对地理信息标准化发展趋势的分析，认为Ｍｅｔａｄａｔａ是地理信息共享的关键技术，并根据Ｍｅｔａｄａｔａ的层次关系，提出了实现Ｍｅｔａｄａｔａ体系的基本模型。结合该模型，作者在Ｍｅｔａｄａｔａ标准草案的基础上，研制了一套基于国家空间信息基础设施（ＮＳＩＩ）的Ｍｅｔａｄａｔａ软件原型。该研究对信息化社会中地学信息的共享具有重要意义。

关键词：地理信息 Metadata 共享体系地学信息

Influence of biological treatments on intestinal microbiota of psoriasis patients

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Chinese Medical Journal 2024年第16期137卷 1996-1998页

作者： Zhuyuan Wen Xiaoling Lu Hao Nie Jing Xu Yang Zou Kun Huang aijun chen Yichi Zhang Min Cao Qi Yin Ping Wang Department of Dermatology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400042China School of Pediatrics Chongqing Medical University Pediatric CollegeChongqing 400016China School of Public Health Chongqing Medical UniversityChongqing 400016China Department of Urology Third People’s Hospital of ChengduChengduSichuan 610014China

To the Editor:Psoriasis is a common,chronic inflammatory skin disease occurring worldwide and presenting at any age.[1]Biologics are the most important therapeutic advances in psoriasis treatment.[2]With the development of 16S rRNA sequencing technology,the association between psoriasis and intestinal flora has been gradually *** bacteria secrete short-chain fatty acids(SCFAs)with anti-inflammatory properties,serving as active microbial metabolites that regulate the function of immune cells in the intestine and other tissues.[3]However,the impact of biological treatment on gut microbiota and related functional changes in psoriasis patients remains *** study aimed to explore the effects of biological treatments on the intestinal microbiota of psoriasis patients.

关键词： psoriasis patients intestine

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氨甲环酸在皮肤科的应用进展

中国麻风皮肤病杂志 2021年第3期37卷 180-184页

作者：唐文陈爱军重庆医科大学附属第一医院皮肤科重庆400016

氨甲环酸是一种常见的抗纤溶药物,目前广泛用于血友病患者拔牙术后止血、其他外科手术或急性创伤止血、月经过多等疾病。越来越多地研究表明它不仅具有抗继发性纤溶作用,还具有抑制血管生成、减少黑色素生成、抗炎、抗变态反应、抗皮肤... 详细信息

氨甲环酸是一种常见的抗纤溶药物,目前广泛用于血友病患者拔牙术后止血、其他外科手术或急性创伤止血、月经过多等疾病。越来越多地研究表明它不仅具有抗继发性纤溶作用,还具有抑制血管生成、减少黑色素生成、抗炎、抗变态反应、抗皮肤自然衰老和光老化作用。在皮肤科领域,氨甲环酸对黄褐斑、炎症后色素沉着、Riehl黑变病等多种疾病具有治疗作用。本文对氨甲环酸在皮肤疾病中的作用机制、疗效、不良反应及安全性进行综述。

关键词：氨甲环酸黄褐斑皮肤疾病

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自紧球形容器内残余应力的弹塑性研究

应用力学学报 2008年第3期25卷 512-515页

作者：陈爱军张新平曾志华南京理工大学南京210094

根据材料的不可压缩性假设,研究了线性强化材料球形容器的弹塑性加卸载过程。通过把材料的包辛格系数考虑为等效塑性应变的函数,建立起了等向硬化、随动硬化和混合硬化模型下的自紧厚壁球壳的残余应力公式。算例分析表明包辛格效应对自... 详细信息

根据材料的不可压缩性假设,研究了线性强化材料球形容器的弹塑性加卸载过程。通过把材料的包辛格系数考虑为等效塑性应变的函数,建立起了等向硬化、随动硬化和混合硬化模型下的自紧厚壁球壳的残余应力公式。算例分析表明包辛格效应对自紧残余应力有较大的影响,最后还通过计算研究了球形容器内残余应力在不同自紧度下的分布情况。

关键词：包辛格效应球形容器自紧分析残余应力

Clinical characteristics and outcomes of psoriasis patients with COVID-19:A retrospective,multicenter cohort study in China

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Chinese Medical Journal 2024年第14期137卷 1736-1743页

作者： Yanhua Liu Zhongrui Xu Jian Zhou aijun chen Junling Zhang Xiaojing Kang Xian Jiang chengzhi Lyu Chunrui Shi Yuling Shi Xiaoming Liu Fuqiu Li Bin Yang Yongmei Huang chen Yu Gang Wang Department of Dermatology Xijing HospitalFourth Military Medical UniversityXi’anShaanxi 710032China Department of Dermatology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Dermatology Tianjin Academy of Traditional Chinese Medicine Affiliated HospitalTianjin 300072China Department of Dermatology and Venereology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqiXinjiang 830001China Department of Dermatology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Psoriasis Dalian Dermatosis HospitalDalianLiaoning 116011China Department of Dermatology The First Hospital of Lanzhou UniversityLanzhouGansu 730000China Skin Disease Hospital of Tongji University Shanghai 200050China Department of Dermatology The University of Hong Kong-Shenzhen HospitalShenzhenGuangdong 518053China Department of Dermatology The Second Hospital of Jilin UniversityChangchunJilin 130000China Department of Dermatology Dermatology Hospital of Southern Medical UniversityGuangzhouGuangdong 510091China Department of Dermatology Xining First People’s HospitalXiningQinghai 810000China

Background:Limited information exists regarding the impact of severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2)infection on psoriasis *** objective of this study was to identify clinical factors associated with the prognosis of psoriasis following SARS-CoV-2 ***:A retrospective,multicenter study was conducted between March and May *** and multivariable logistic regression analyses were employed to identify factors associated with coronavirus disease 2019(COVID-19)-related psoriasis *** study included 2371 psoriasis patients from 12 clinical centers,with 2049 of them having been infected with ***:Among the infected groups,lower exacerbation rates were observed in individuals treated with biologics compared to those receiving traditional systemic or nonsystemic treatments(22.3%[236/1058]vs.39.8%[92/231]vs.37.5%[140/373],P<0.001).Psoriasis progression with lesions(adjusted odds ratio[OR]=8.197,95%confidence interval[95%CI]=5.685-11.820,compared to no lesions),hypertension(adjusted OR=1.582,95%CI=1.068-2.343),traditional systemic(adjusted OR=1.887,95%CI=1.263-2.818),and nonsystemic treatment(adjusted OR=1.602,95%CI=1.117-2.297)were found to be associated with exacerbation of psoriasis after SARS-CoV-2 infection,but not biologics(adjusted OR=0.931,95%CI=0.680-1.274,compared to no treatment),according to multivariable logistic regression ***:A reduced risk of psoriasis exacerbation after SARS-CoV-2 infection was observed with biologics compared to traditional systemic and nonsystemic *** risk factors for exacerbation after infection were identified as existing psoriatic lesions and hypertension.

关键词： COVID-19 SARS-CoV-2 Psoriasis Treatment Biologics

基于NVD的半圆式钢桁梁异型斜拉桥抗震性能分析

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自然灾害学报 2021年第5期30卷 147-154页

作者：陈爱军周彦贺国京中南林业科技大学土木工程学院湖南长沙410004

为研究非线性粘滞阻尼器(Nonlinear Viscous Dampers,NVD)的特征参数与不同布设方案对半圆式钢桁梁异型斜拉桥抗震性能的影响。以某景观斜拉桥为研究对象,分别对两种NVD布设方案下的不同阻尼系数、速度指数以及不设阻尼器的ANSYS有限元... 详细信息

为研究非线性粘滞阻尼器(Nonlinear Viscous Dampers,NVD)的特征参数与不同布设方案对半圆式钢桁梁异型斜拉桥抗震性能的影响。以某景观斜拉桥为研究对象,分别对两种NVD布设方案下的不同阻尼系数、速度指数以及不设阻尼器的ANSYS有限元模型开展了非线性时程分析与抗震随机分析。以桥梁跨中最大位移响应与跨中最大弯矩响应为主要特征点,对比分析了地震荷载激励下桥梁结构的抗震性能,并对抗震效果最佳的NVD布设方案进行了抗震随机分析。研究结果表明:(1)NVD的引入使得桥梁结构在地震荷载激励下所产生的位移响应与弯矩响应均得到了显著的控制;(2)在地震荷载作用下,桥梁跨中最大位移响应、跨中最大弯矩响应与一定范围内的NVD特征参数取值呈负相关,但相比于阻尼系数,速度指数的增大对结构最大位移响应的控制效果更为显著;(3)引入NVD使得抗震随机分析结果中的结构位移响应峰值能够较大概率地保持在一个较低的水平,NVD可以提高桥梁的抗震性能。

关键词：异型斜拉桥钢桁梁非线性粘滞阻尼器位移响应弯矩响应抗震性能抗震随机分析

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磁流变阻尼器的电流驱动器的设计与测试

仪器仪表学报 2006年第8期27卷 928-931页

作者：余淼陈爱军廖昌荣张红辉陈伟民重庆大学光电技术及系统教育部重点实验室重庆400044

动态响应时间是磁流变阻尼器的一个重要指标,它与驱动电路的形式密切相关。相对于电压源驱动,电流源驱动能显著缩短磁流变阻尼器线圈中励磁电流的瞬态响应过程。本文采用PWM开关方式设计了一种用于汽车磁流变阻尼器的电流驱动器,并连接... 详细信息

动态响应时间是磁流变阻尼器的一个重要指标,它与驱动电路的形式密切相关。相对于电压源驱动,电流源驱动能显著缩短磁流变阻尼器线圈中励磁电流的瞬态响应过程。本文采用PWM开关方式设计了一种用于汽车磁流变阻尼器的电流驱动器,并连接实际磁流变阻上升响应时间约为3.10ms,阶跃下降响应时间约为13.20ms。

关键词：磁流变阻尼器电流驱动器 PWM 响应时间