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COVID-19 with asthma:A case report

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World Journal of Clinical Cases 2020年第15期8卷 3355-3364页

作者： ai-ling liu Ning Xu ai-jun li Department of Pulmonary and Critical Care Medicine Weihai Municipal HospitalShandong UniversityWeihai 264200Shandong ProvinceChina

BACKGROUND Coronavirus disease 2019(COVID-19)is a public health emergency of international *** global population lacks immunity to COVID-19 and is generally *** conditions,especially chronic respiratory diseases,may affect progression,treatment and prognosis of *** SUMMARY We report a patient with confirmed COVID-19 combined with *** took 41 d from disease onset to discharge to obtain two negative tests for this *** This case indicates the dynamic clinical characteristics,laboratory and computed tomography findings and adjustment of treatment,and the possible relationship between glucocorticoid therapy and coronavirus clearance.

关键词： COVID-19 Asthma Glucocorticoids Respiratory passage mucosa immune system Case report

1-[2-(2-Methoxyphenylthio) benzyl]-4-arylpiperazines derivatives:Synthesis and evaluation for dual 5-HT_(1A)/SSRI activities

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Chinese Chemical Letters 2008年第1期19卷 37-39页

作者： Xin Wang Dong Zhi liu ai jun li School of Chemical Engineering and Technology Tianjin University Tianjin 300072 China School of Pharmaceutical Science and technology Tianjin University Tianjin 300072 China

A series of 1-[2-（2-methoxyphenylthio） benzyl]-4-arylpiperazines derivatives was designed and synthesized based on 5-HT1A/ SSRI drugs design strategies. The synthesized compounds were evaluated for their dual 5-HT1A/5-HTT activities. 2007 ai jun li. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Antidepressants 5-HT1A/5-HTT Serotonin transporter 5-HT1A receptor Diphenylsulfide

1-(N-(2-(2-Methoxyphenylthio)benzyl)-N-methylamino-3-aryloxypropan-2-ols:Synthesis and evaluation for dual 5-HT_(1A)/SSRI activities

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Chinese Chemical Letters 2008年第1期19卷 40-42页

作者： Xin Wang Dong Zhi liu ai jun li School of Chemical Engineering and Technology Ttanjin University 7ianjin 300072 China School of Pharmaceutical Science and Technology Tianjin University Tianjin 300072 China

A series of 1-（N-（2-（2-methoxyphenylthio）benzyl）-N-methylamino-3-aryloxypropan-2-ols derivatives were designed and synthesized based on 5-HT1A/SSRI drugs design strategies. The synthesized compounds were evaluated for their dual 5-HT1A/ 5-HTT activities. 2007 ai jun li. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： 5-HT1A/SSRI Serotonin transporter 5-HT1A receptor Diphenylsulfide

Modeling of high-temperature reforming reactor based on interactive thermal control with a tail gas combustor

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Advances in Manufacturing 2016年第1期4卷 47-54页

作者： Dan Zhang Zhong Shao Ji-Ping Xin ai-jun li Shanghai Key Laboratory of Mechanics in EnergyEngineering Institute of Applied Mathematics andMechanics Shanghai University Shanghai 200444People's Republic of China Research Center of Composite Materials ShanghaiUniversity Shanghai 200444 People's Republic of China

This paper proposes a method to model hydrocarbon reforming by coupling detailed chemical kinetics with complex computational fluid dynamics. The entire chemistry of catalyzed reactions was confined within the geometrically simple channels and modeled using the low-dimensional plug model, into which the interactive thermal control of the multi-channel reforming reactor has been implemented with a tail-gas combustor around the external surface of these catalytic channels. The geomet- rically complex flow in the tail gas combustor was simu- lated using FLUENT without involving any chemical reactions. The influences of the conditions at the reactor inlet such as the inlet gas velocity, the inlet gas composi- tion and the variety of hydrocarbons of each channel on gas conversions were investigated numerically. The impact of the tail gas combustor setup on the efficiency of the reforming reactor was also analyzed. Methane catalytic partial oxidation （CPOx） and propane steam reforming （SR） were used to illustrate the approach reported in the present work.

关键词： Computational fluid dynamics Reactionkinetics Catalytic partial oxidation Steam reforming

Spray-coated SnO_(2) electron transport layer with high uniformity for planar perovskite solar cells

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Frontiers of Chemical Science and Engineering 2021年第1期15卷 180-186页

作者： Yaqin Wang lin Yang Chunxiang Dall’Agnese Gang Chen ai-jun li Xiao-Feng Wang Key Laboratory of Physics and Technology for Advanced Batteries(Ministry of Education) College of PhysicsJilin UniversityChangchun 130012China College of Physics Jilin UniversityChangchun 130012China

SnO_(2) has been proven to be an effective electron transport layer(ETL)material for perovskite solar cells(PSCs)owing to its excellent electrical and optical ***,we introduce a viable spray coating method for the preparation of SnO2 ***,we employ a SnO_(2) film prepared using the spray coating method as an ETL for *** PSC based on the spray-coated SnO_(2) ETL achieves a power conversion efficiency of 17.78%,which is comparable to that of PSCs based on conventional spin-coated SnO_(2) *** large-area SnO_(2) films prepared by spray coating exhibit good repeatability for device *** study shows that SnO_(2) films prepared by spray coating can be applied as ETLs for stable and high-efficiency *** the proposed method involves low material consumption,it enables the low-cost and large-scale production of PSCs.

关键词： spray coating SnO_(2)film ETL PSCs

N-(2-(2-Methoxyphenylthio)benzyl)-2-aryloxyethylamines:Synthesis and evaluation for dual 5-HT_(1A)/SSRI activities

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Chinese Chemical Letters 2008年第3期19卷 295-298页

作者： Xue Dan Wu Dong Zhi liu ai jun li Xue Qin Zhou School of Chemical Engineering and Technology lianjin University lianjin 300072 China College of Chemical and Pharmaceutical Engineering Hebei University of Science and TechnologyShijiazhuang 050018 China

The design, synthesis and biological evaluation of N-（2-（2-methoxyphenylthio） benzyl）-2-aryloxyethyl amines with dual 5-HT1A/SSR/activities are reported. Compound 8e displays the best dual activities and is a prom... 详细信息

关键词： Antidepressants 5-HT1A/5-HTT 5-HT1A receptor Diphenylsulfide Aryloxyethylamines

New 3-(4-arylpiperazin-1-yl)-1-(benzo[b]thiophen-3-yl)-2-methylpropanol derivatives:Synthesis and evaluation for dual 5-HT1A/SSRI activities

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Chinese Chemical Letters 2008年第4期19卷 412-414页

作者： ai jun li Xiao Hua Zhang Xue Qin Zhou Dong Zhi liu School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China College of Chemical and Pharmaceutical Engineering Hebei University of Science and TechnologyShijiazhuang 050018China

A series of 3-（4-arylpiperazin-1-yl）-1-（benzo[b]thiophen-3-yl）-2-methylpropanol derivatives were designed and synthesized based on 5-HT1A/SSRI drugs design *** synthesized compounds were evaluated for their dual 5... 详细信息

关键词： Antidepressants Arylpiperazines 5-HT1A/SSRI 5-HT transporter 5-HT1A receptor

Arylpiperazine derivatives of diphenylsulfide:Synthesis and evaluation for dual 5-HT_(1A)/SSRI activities

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Chinese Chemical Letters 2008年第3期19卷 291-294页

作者： Xue Dan Wu Dong Zhi liu ai jun li Xue Qin Zhou School of Chemical Engineering and Technology Tianjin University Tianjin 300072 China College of Chemical and Pharmaceutical Engineering Hebei University of Science and Technology. Shijiazhuang 050018 China

The design, synthesis and biological evaluation of a novel series of arylpiperazine derivatives of diphenylsulfide with dual 5- HT1A/SSRI activities are reported. The target compounds exhibit low to moderate 5-HT transporter affinity and moderate to high 5- HT1A affinity, Compound 13a shows moderate dual activities and is a promising lead compound for further structure-activity relationships studies.

关键词： Antidepressants 5-HT1A/SSRI Arylpiperazines 5-HT1A receptor Diphenylsulfide

Hydrogenation of graphene nanoflakes and C-H bond dissociation of hydrogenated graphene nanoflakes： a density functional theory study

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Advances in Manufacturing 2017年第3期5卷 289-298页

作者： Sheng Tao Hui-Ting liu liu-Ming Yan Bao-Hua Yue ai-jun li Department of Chemistry College of Sciences ShanghaiUniversity Shanghai 200444 P. R. China Research Center for Composite Materials ShanghaiUniversity Shanghai 200444 P. R. China

The Gibbs free energy change for the hydro- genation of graphene nanoflakes Cn （n = 24, 28, 30 and 32） and the C-H bond dissociation energy of hydrogenated graphene nanoflakes CnHm （n = 24, 28, 30 and 32; and m = 1, 2 and 3） are evaluated using density functional theory calculations. It is concluded that the graphene nanoflakes and hydrogenated graphene nanoflakes accept the orth- aryne structure with peripheral carbon atoms bonded via the most triple bonds and leaving the least unpaired dan- gling electrons. Five-membered rings are formed at the deep bay sites attributing to the stabilization effect from the pairing of dangling electrons. The hydrogenation reactions which eliminate one unpaired dangling electron and thus decrease the overall multiplicity of the graphene nanoflakes or hydrogenated graphene nanoflakes are spontaneous with negative or near zero Gibbs free energy change. And the resulting C-H bonds are stable with bond dissociation energy in the same range as those of aromatic compounds. The other C-H bonds are not as stable attributing to the excessive unpaired dangling electrons being filled into the C-H anti-bond orbital.

关键词： Graphene nanoflake · Hydrogenated graphenenanoflake. Orth-aryne · Hydrogenation reaction· Bonddissociation energy · Density functional theory