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Pulmonary Diseases Decision Support System Using Deep Learning Approach

Computers, Materials & Continua 2022年第10期73卷 311-326页

作者： Yazan al-issa ali Mohammad alqudah Hiam alquran ahmed al issa Department of Computer Engineering Yarmouk UniversityIrbid21163Jordan Department of Biomedical Systems and Informatics Engineering Yarmouk UniversityIrbid21163Jordan Department of Biomedical Engineering Jordan University of Science and TechnologyIrbid 22110Jordan Pediatrician Mediclinic HospitalAl Ain14444UAE

Pulmonary diseases are common throughout the world,especially in developing *** diseases include chronic obstructive pulmonary diseases,pneumonia,asthma,tuberculosis,fibrosis,and recently *** general,pulmonary diseases have a similar footprint on chest radiographs which makes them difficult to discriminate even for expert *** recent years,many image processing techniques and artificial intelligence models have been developed to quickly and accurately diagnose lung *** this paper,the performance of four popular pretrained models(namely VGG16,DenseNet201,DarkNet19,and XceptionNet)in distinguishing between different pulmonary diseases was *** the best of our knowledge,this is the first published study to ever attempt to distinguish all four cases normal,pneumonia,COVID-19 and lung opacity from ChestX-Ray(CXR)*** models were trained using Chest-X-Ray(CXR)images,and statistically tested using 5-fold cross *** individual models,XceptionNet outperformed all other models with a 94.775%accuracy and Area Under the Curve(AUC)of Receiver Operating Characteristic(ROC)of 99.84%.On the other hand,DarkNet19 represents a good compromise between accuracy,fast convergence,resource utilization,and near real time detection(0.33 s).Using a collection of models,the 97.79%accuracy achieved by Ensemble Features was the highest among all surveyed methods,but it takes the longest time to predict an image(5.68 s).An efficient effective decision support system can be developed using one of those approaches to assist radiologists in the field make the right assessment in terms of accuracy and prediction time,such a dependable system can be used in rural areas and various healthcare sectors.

关键词： Pulmonary diseases deep learning lung opacity classification majority voting ensemble features

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Sickle cell cholangiopathy:An endoscopic retrograde cholangiopancreatography evaluation

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World Journal of Gastroenterology 2009年第42期15卷 5316-5320页

作者： Hussain issa ali al-Haddad ahmed al-Salem Department of Internal Medicine Division of GastroenterologyKing Fahad Specialist HospitalDammam 31444Saudi Arabia Department of Internal Medicine Qatif Central HospitalQatif 31911Saudi Arabia Department of Pediatric Surgery Maternity and Children HospitalDammamQatif 31911Saudi Arabia

AIM:To evaluate the role of endoscopic retrograde cholangiopancreatography(ERCP) in patients with sickle cell disease(SCD) .METHODS:Two hundred and twenty four SCD patients with cholestatic jaundice(CJ) had *** indications for ERCP were based on clinical and biochemical evidence of CJ and ultrasound ***:Two hundred and forty ERCPs were *** indications for ERCP were:CJ only in 79,CJ and dilated bile ducts without stones in 103,and CJ and bile duct stones in *** those with CJ only,ERCP was normal in 42(53.2%) ,and 13(16.5%) had dilated bile ducts without an obstructive *** the remaining 22,there were bile duct stones with or without *** those with CJ,dilated bile ducts and no stones,ERCP was normal in 17(16.5%) ,and 28(27.2%) had dilated bile ducts without an obstructive *** the remaining 58,there were bile ducts stones with or without *** those with CJ and bile duct stones,ERCP was normal in two(4.8%) ,and 14(33.3%) had dilated bile ducts without an obstructive *** the remaining 26,there were bile duct stones with or without ***:Considering the high frequency of biliary sludge and bile duct stones in SCD,endoscopic sphincterotomy might prove helpful in these patients.

关键词： Sickle cell disease Hepatobiliary Cholestsatic jaundice Sickle cell hepatopathy Sickle cell cholangiopathy Endoscopic retrograde cholangiopancreatography

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Role of ERCP in the era of laparoscopic cholecystectomy for the evaluation of choledocholithiasis in sickle cell anemia

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World Journal of Gastroenterology 2011年第14期17卷 1844-1847页

作者： Hussain issa Arabia ahmed H al-Salem Department of Internal Medicine King Fahad Specialist HospitalDammamQatif 31911Saudi Department of Pediatric Surgery Maternity and Children HospitalDammamQatif 31911Saudi Arabia

AIM:To evaluate the role of endoscopic retrograde cholangiopancreatography (ERCP) for choledocholithiasis in patients with sickle cell anemia (SCA) in the era of laparoscopic cholecystectomy (LC). METHODS:Two hundred and twenty four patients (144 male,80 female; mean age,22.4 years; range,5-70 years) with SCA underwent ERCP as part of their evaluation for cholestatic jaundice (CJ). The indications for ERCP were:CJ only in 97,CJ and dilated bile ducts on ultrasound in 103,and CJ and common bile duct (CBD) stones on ultrasound in 42. RESULTS:In total,CBD stones were found in 88 (39.3%) patients and there was evidence of recent stone passage in 16. Fifteen were post-LC patients. These had endoscopic sphincterotomy and stone extraction. The remaining 73 had endoscopic sphincterotomy and stone extraction followed by LC without an intraoperative ***:In patients with SCA and cholelithiasis,ERCP is valuable whether preoperative or postoperative,and in none was there a need to perform intraoperative cholangiography. Sequential endoscopic sphincterotomy and stone extraction followed by LC is beneficial in these patients. Endoscopic sphincterotomy may also prove to be useful in these patients as it may prevent the future development of biliary sludge and bile duct stones.

关键词： Sickle cell anemia Cholelithiasis Choledocholithiasis Laparoscopic cholecystectomy Cholangiography Endoscopic retrograde cholangiopancreatography

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AN EValUATION OF INDOOR ENVIRONMENTal QUalITY AND OCCUPANT WELL-BEING IN MANITOBA SCHOOL BUILDINGS

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Journal of Green Building 2017年第1期12卷 123-141页

作者： ahmed Radwan Mohamed H.issa Faculty of Engineering Department of Civil EngineeringUniversity of ManitobaRoom E1-368A EITC15 Gillson StreetWinnipegMB R3T 5V6 Canada Faculty of Engineering Department of Civil EngineeringUniversity of Manitoba Room E3-589 EITC15 Gillson StreetWinnipegMB R3T 5V6Canada

This exploratory research aims to evaluate indoor environmental quality in the classrooms of three school buildings in Southern Manitoba,Canada,and to evaluate the well-being of these schools’teachers as it pertains to their perception of their classrooms’indoor *** schools include a middle-aged,conventional school;a new,non-green school;and a new,green school certified using the Leadership in Energy and Environmental Design rating *** methodology involved using a mobile instrument cart to conduct snapshot measurements of thermal comfort,indoor air quality,lighting and acoustics in classrooms and an occupant survey to evaluate teachers’long-term satisfaction with their classrooms’indoor environmental *** results showed that the new,green and new,non-green schools’classrooms performed better than the conventional,middle-aged school’s classrooms with respect to some aspects of thermal comfort and indoor air quality *** in the new,green school and in the new,non-green school were more satisfied than teachers in the conventional,middle-aged school with their classrooms’overall indoor environmental quality,lighting quality and indoor air ***,the new,green and new-non green school classrooms’performance were very comparable with the new,green school’s classrooms performing statistically significantly better with respect to relative ***,none of the differences in teachers’satisfaction ratings between the new,green and new,non-green school were statistically significant.

关键词： building performance evaluation post occupancy evaluation indoor environment building energy use

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Geochemical characteristics of natural gases and source rocks in Obayied sub-basin,north Western Desert,Egypt:implications for gas-source correlation

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Acta Geochimica 2023年第2期42卷 241-255页

作者： Mostafa Hassan Mahmoud Leila Mohammed ahmed Ghalib issa Omar Hegab Geology Department Faculty of ScienceMansoura UniversityMansoura 35516Egypt Egyptian General Petroleum Corporation CairoEgypt

Western Desert represents a major oil and gas province in Egypt producing more than 50%of the country’s oil *** and gas blend occurs in most producing fields,however,the genetic link between gas and liquid hydrocarbon phases are not *** sub-basin in the Western Desert where oil and gas phases coexist in the Middle Jurassic sandstones of the Khatatba Formation provides an ideal place to investigate the link between oil and gas *** analyses on rock samples(Rock–Eval pyrolysis,vitrinite reflectance,R_(o))and gases(molecular and isotopic composition)were conducted in order to identify the genetic characteristics of the hydrocarbon phases ***-relevant parameters(Rock–Eval T_(max),vitrinite reflectance R_(o))elucidate that only Middle Jurassic Khatatba organofacies capable of generating wet and dry hydrocarbon ***,the enrichment of C_(7)normal alkanes,mono-branched alkanes relative to polybranched components in the Obayied gases reflect their generation via cracking of *** modelling results confirm gas generation through both primary and secondary ***,secondary cracking of liquid hydrocarbon phases is volumetrically more *** cracking of the Khatatba organofacies likely predate and catalyze the secondary cracking of the liquid phases and therefore the volume of generated gas increases incrementally eastward where both processes *** present study highlights the significant role of secondary cracking in the generation and accumulation of huge gas accumulations in the basins containing oil-prone source intervals.

关键词： Primary and secondary cracking Gas geochemistry Jurassic Khatatba Obayied Western Desert

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Hydrocarbon-Source Correlation in the Obayied Sub-Basin,North Western Desert,Egypt:Controls on Generation of Natural Gas and Light Crude Hydrocarbon Blends

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Journal of Earth Science 2024年第6期35卷 1944-1965页

作者： Mostafa Hassan Mahmoud Lotfy Leila Mohammed ahmed Ghalib issa Branimir Segvie Omar Hegab Geology Department Faculty of ScienceMansoura UniversityMansouraEgypt School of Mining and Geosciences Nazarbayev UniversityAstanaKazakhstan Department of Geosciences Texas Tech UniversityLubbockTX79409USA

Obayied sub-basin provides one-third of the annual natural gas production in the Egyptian Western *** origin of the Obayied hydrocarbons are however poorly *** this study,the molecular biomarkers of the Obayied hydrocarbon blend were studied to infer on their origin and generation *** API values are in the range of(41.3°-53.7°)reflecting post-mature *** molecular biomarkers suggest a generation of Obayied crude from clay-rich fluviodeltaic source ***-and maturity-relevant biomarkers(e.g.,Ts/Tm trisnorhopanes and methylphenanthrene indices)reflect a successive expulsion of the Obayied crudes from mature Jurassic rocks(>1%Ro).Biological markers correlate perfectly with those of the Jurassic Khatatba shale and coal extracts ***,the Obayied gases are wet,thermogenic and have been derived from a mature typeⅢkerogen(1.3%Ro-2%Ro).The studied gases display compositional characteristics of mixed coal-and oil-type gases,and were therefore derived via primary cracking of the Khatatba coal as well as secondary cracking of the light liquid *** present study clarifies the controls on the geochemical processes responsible for the accumulation of liquid and gas hydrocarbon mix in the deep as well as shallow inverted rift basins of the north Western Desert,Egypt.

关键词： natural gas hydrocarbons molecular biomarkers kerogen Jurassic Khatatba Western Desert Egypt

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MicroRNA signature in patients with hepatocellular carcinoma associated with type 2 diabetes

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World Journal of Gastroenterology 2019年第42期25卷 6322-6341页

作者： Moustafa Nouh Elemeery Marwa Anwar Mohamed Marwa ahmed Madkour Mohammed Mohammed Shamseya Noha Mahmoud issa ahmed Noah Badr Doaa ahmed Ghareeb Cheol-Ho Pan Département de Neurosciences CRCHUMUniversitéde MontréalMontréalQuebec H2X 3E4Canada Medical Biotechnology Laboratory Genetic Engineering and Biotechnology Research DivisionNational Research CentreCairo 12622Egypt Natural Product Informatics Research Center KIST Gangneung Institute of Natural ProductsGangneung 25451South Korea Division of Bio-Medical Science and Technology KIST SchoolKorea University of Science and TechnologySeoul 02792South Korea Department of Chemical Pathology Medical Research InstituteAlexandria UniversityAlexandria 21511Egypt Experimental and Clinical Internal Medicine Department Medical Research InstituteAlexandria UniversityAlexandria 21511Egypt Human Genetics Department Medical Research InstituteAlexandria UniversityAlexandria 21511Egypt Food Toxicology and Contaminates Department National Research CentreDokkiCairo 12622Egypt Bioscreening and preclinical trial lab Biochemistry DepartmentFaculty of ScienceAlexandria UniversityAlexandria 12522Egypt Pharmaceutical and fermentation industries development center the city of scientific research and technological applicationsAlexandria 26411Egypt

BACKGROUND Nonalcoholic steatohepatitis-related cirrhosis is one of the liver complications in type 2 diabetes mellitus(T2DM)and reported to be a risk factor for developing hepatocellular carcinoma(HCC).A reliable screening biomarker of liver cirrhosis(LC)and HCC among T2DM patients is important to reduce the morbidity and mortality of this ***(miRNA)is considered a key player in HCC and T2DM,and it might be a hidden culprit in diabetes-associated HCC,making it a promising reliable prognostic *** To investigate the signature of serum miRNAs as early biomarkers for the screening of HCC among diabetic *** Expression profiles of miRNAs in serum samples of diabetic LC and diabetic HCC patients were assessed using Illumina sequencing;then,RT-qPCR was used to validate significantly altered miRNAs between the two *** miRNAs were tested in serum samples of 200 T2DM patients,270 LC patients,200 HCC patients,and 225 healthy control ***,receiver operating characteristic(ROC)analysis,with area under the curve(AUC),was performed to assess the diagnostic performance of the screened miRNAs for discriminating HCC from LC and nonmalignant patients(LC+T2DM).RESULTS Expression of the sequenced miRNAs in serum was different in HCC vs LCpositive T2DM *** miRNAs(miR-34a,miR-221)were significantly upregulated and five miRNAs(miR-16,miR-23-3p,miR-122-5p,miR-198,miR-199a-3p)were significantly down-regulated in HCC compared to LC *** of ROC curve demonstrated that the combination of these seven miRNAs can be used as a reliable biomarker for detection of HCC in diabetic patients,as it could identify HCC with high diagnostic accuracy in diabetic LC patients(AUC=0.993)and in diabetic nonmalignant patients(AUC=0.961).CONCLUSION This study validates a panel of serum miRNAs that can be used as a reliable noninvasive screening biomarker of HCC among T2DM cirrhotic and noncirrhotic *** study recommends furt

关键词： MicroRNA Hepatocellular carcinoma Type 2 diabetes Nonalcoholic fatty liver disease

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Migration of a biliary stent causing duodenal perforation and biliary peritonitis

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World Journal of Gastrointestinal Endoscopy 2013年第10期5卷 523-526页

作者： Hussain issa Mamdouh Nahawi Bahaa Bseiso ahmed al-Salem Department of Internal Medicine King Fahad Specialist Hospital Department of Surgery King Fahad Specialist Hospital Department of Pediatric Surgery Maternity and Children Hospital

Migration of endoscopically placed biliary stents is a well-recognized complication of endoscopic retrograde cholangiopancreatography. Less than 1% of migrated stents however cause intestinal perforation. We present a... 详细信息

关键词： Biliary stents Migration Duodenal perforation Biliary peritonitis

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The influence of treatment modality on illness perception and secondary prevention outcomes among patients with acute myocardial infarction

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International Journal of Nursing Sciences 2017年第3期4卷 271-277页

作者： ahmed Mohammad al-Smadi Loai issa Tawalbeh ala Ashour issa M.Hweidi Besher Gharaibeh Paul Slater Donna Fitzsimons Faculty of Nursing American University of MadabaAmman Jordan Faculty of Nursing Al-AlBayt UniversityP.O.Box:130040Al-Mafraq 25113Jordan Faculty of Nursing The Hashemite UniversityAl-ZarqaJordan Jordan University of Science and Technology IrbidJordan University of Ulster School of NursingUnited Kingdom Queen's University of Belfast United Kingdom

Objectives:This study aims to determine if patients with acute myocardial infarction differ in illness perception and secondary prevention outcomes depending on the treatment they ***:A repeated measures design was used to compare patients with acute myocardial infarction receiving three different treatment modalities:ST-elevation myocardial infarction treated by primary percutaneous coronary intervention,ST-elevation myocardial infarction treated by thrombolytic therapy,and non ST-elevation myocardial infarction treated by medication.A convenient sampling technique was used to recruit 206 patients with acute myocardial infarction who agreed to participate in the current ***'illness perception,physical activity,and demographical and clinical data were collected during hospital admission and again at 6 ***:A total of 186 patients completed the *** showed that the primary percutaneous coronary intervention group perceived their illness as acute rather than chronic(P=0.034)and has lower personal control(P=0.032),higher treatment control(P=0.025),and higher perception of illness coherence(P=0.022)compared with patients receiving thrombolytic therapy and treated after non-ST segment ***,they report low control of their blood pressure(P=0.013)and less physical activity(P=0.001).Conclusion:The results of this study revealed that patients'treated with primary percutaneous coronary intervention had negative illness perception and limited behavioral changes 6 months after hospitalization in comparison with other treatment modalities such as percutaneous coronary intervention and thrombolytic *** research is recommended to confirm this association with longer follow-up study and among different cultures.

关键词： Acute myocardial infarction Illness perception Primary percutaneous coronary intervention Secondary prevention

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Phytochemical Constituents and allelopathic Effects of Some Medicinal Plants Extract on the Soil algal Diversity

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Journal of Agricultural Science and Technology(A) 2013年第12期3卷 1000-1009页

作者： Mustafa ahmed Fawzy AwatiefFahmey Hifney ahmed Abdel-Salam issa Gamal Gareib Botany & Microbiology Department Faculty of Science Assiut University Assiut 71516 Egypt

Phytochemical constituents of the shoots and roots extract of chosen eight medicinal plants （Plantago major, Verbesina encelioides, Glinus lotoides, Helotropium supinum, Mentha microphylla, Euphorbia hirta, Juncus subulatus and Convolvulus arvensis） were estimated using standard qualitative analysis. The extract contained alkaloids, glycosides, saponins, phenols, tannins, f[avonoids and terpenoids in some medicinal plants while others contain some only of these phytochemical components. allelopathic effect of the various concentrations of the extracts on the soil algal diversity was also investigated. Wollea saccata was the only algal species disappeared from all applied investigated plant extracts. Phormidium richardsii, Monoraphidium braunii, Eunotia verneris and Nitzschia bilobata were the highly sensitive algal species to all applied shoot and root extract from all tested plants, they disappeared from most of the studied plants. On the other hand, Phormidium animale and Chlorella neustonice were highly tolerant algal species to all applied extracts. Counts of Cyanophyceae, Chlorophyceae and Bacillariophyceae were decreased by addition of some investigated medicinal plants extracts such as Juncus subulatus, Convolvulus arvensis and Euphorbia hirta. So the authors can use these plants extracts in biocontrol of the nuisance of algal bloom or any other microorganisms. also, these plants may be useful to recover eutrophic water which needs further investigation.

关键词： allelopathy allelochemicals Plantago major Verbesina encelioides Glinus lotoides Phormidium richardsii,Monoraphidium braunii.

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