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Investigation on the mechanical properties of sintered porous copper compacts

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China Particuology 2007年第6期5卷 391-394页

作者： Yasser M.Z. ahmed Mohamed I. Riad ahmed I. zaky Mohammed Abdel-Aziz Mohamed M.H. Shalabi Central Metallurgical Research and Development Institute CMRDI El-Felzat Street El-Tabbin P.O. Box 87 Helwan Cairo Egypt

In line with recent attention on porous metals having low and medium porosities in the range of 20-50%, this paper studies the effect of porosity on the mechanical properties of sintered copper compacts. Experiments were designed to investigate the effect of porosity, applied stress and sliding velocity on the wear rate of copper compacts, leading to the finding that the effects of both porosity and applied stress of the wear test on the wear rate are approximately similar and higher than that of sliding velocity. The investigation concerning the effect of porosity on compressive strength indicated that the stress-strain curve of high-porosity compact exhibited identifiable ultimate strength points, though low-porosity compact showed distinct stages of elastic plastic behavior.

关键词： Porous copper Wear rate Compressive strength Experimental design technique

Monoclonal antibody-based cancer therapies

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Chinese Journal of Chemical Engineering 2021年第2期34卷 301-307页

作者： Yingnan Si Arin L.Melkonian Keegan C.Curry Yuanxin Xu Maranda Tidwell Mingming Liu ahmed F.zaky Xiaoguang(Margaret)Liu Department of Biomedical Engineering University of Alabama at Birmingham(UAB)1825 University BlvdBirminghamAL 35294USA Department of Medicine UAB17202nd Ave S.BirminghamAL 35294USA Chinese Medicine Hospital 98 Shengcheng StreetShouguang 262700China Department of Anesthesiology and Perioperative Medicine UAB62519th Street SouthBirminghamAL 35294USA

Targeted therapy has been widely demonstrated as an effective strategy to treat cancers,the leading cause of death in the *** minireview summarizes the technical platforms and methodologies utilized to develop and engineer therapeutic monoclonal antibodies and antibody-drug ***,the USA FDA approved monoclonal antibody(mAb)-based targeted therapies are *** the representative innovative chimeric,humanized and fully human anti-cancer antibodies and antibody-drug conjugates are ***,the past and predictive market trend of therapeutic antibodies is discussed.

关键词： Monoclonal antibody Antibody-drug conjugate Anti-cancer therapy Market

Generative Neural Network Based Spectrum Sharing Using Linear Sum Assignment Problems

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China Communications 2020年第2期17卷 14-29页

作者： ahmed Bzaky Joshua Zhexue Huang Kaishun Wu Basem MElHalawany Big Data Institute Shenzhen University518060China Benha University Benha13511Egypt Guangdong Laboratory of Artificial Intelligence and Digital Economy(SZ) Shenzhen UniversityShenzhen 518060China PCL Research Center of Networks and Communications Peng Cheng LaboratoryShenzhen 518060China

Spectrum management and resource allocation(RA)problems are challenging and critical in a vast number of research areas such as wireless communications and computer *** traditional approaches for solving such problems usually consume time and memory,especially for large-size *** different machine learning approaches have been considered as potential promising techniques for combinatorial optimization problems,especially the generative model of the deep neural *** this work,we propose a resource allocation deep autoencoder network,as one of the promising generative models,for enabling spectrum sharing in underlay device-to-device(D2D)communication by solving linear sum assignment problems(LSAPs).Specifically,we investigate the performance of three different architectures for the conditional variational autoencoders(CVAE).The three proposed architecture are the convolutional neural network(CVAECNN)autoencoder,the feed-forward neural network(CVAE-FNN)autoencoder,and the hybrid(H-CVAE)*** simulation results show that the proposed approach could be used as a replacement of the conventional RA techniques,such as the Hungarian algorithm,due to its ability to find solutions of LASPs of different sizes with high accuracy and very fast execution ***,the simulation results reveal that the accuracy of the proposed hybrid autoencoder architecture outperforms the other proposed architectures and the state-of-the-art DNN techniques.

关键词： autoencoder linear sum assignment problems generative models resource allocation

Synthesis of Some New Diazo Disperse Dyes and Their Application on Dyeing of Polyester

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Journal of Chemistry and Chemical Engineering 2011年第2期5卷 150-158页

作者： ahmed zaky Sayed Mahmoud Sayed Aboul-Fetouh Hesham Sayed Nassar Chemistry Department University College P.O.Box 2064Umm Al-Qura University Makkah Al-Mokaramah Al-Aziziah 21955 Saudia Arabia Chemistry Department Faculty of Science A l-Azhar University Cairo 11884 Egypt

The synthesis of some new diazo disperse dyes containing a pyrazol-5-one was described. The structures of the new products have been deduced from elemental analysis and spectral dada such as UV-Vis absorption, IR, ^1H NMR, and MS spectroscopy. These dyestuffs gave satisfactory results when applied as disperse dyes to polyester fabric. The dyeing properties such as light fasmess, washing fastness and exhaustion studies have been investigated.

关键词： Pyrazolin-5-one disperse dyes disazo dyes dyeing exhaustion fastness

Impact of auditory stimulation nursing protocol on auditory response in cerebrovascular stroke patients

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Journal of Integrative Nursing 2024年第2期6卷 111-116页

作者： Mohammed ElSayed zaky Hanan ahmed AL SEBAEE Nagat El Morsy IBRAHIEM Heba ahmed MOHAMMED Mohammad Edrees MOHAMMAD Department of Medical Surgical Nursing Faculty of NursingCairo UniversityCairoEgypt Department of Neurology Faculty of MedicineCairo UniversityCairoEgypt

Objectives:The objective of the study was to explore the impact of auditory stimulation protocol on auditory response in cerebrovascular stroke(CVS)*** and Methods:A pre-posttest nonequivalent control group quasi-experimental study was conducted at Al Mainal Hospital at Al Kars Einy Hospital,Cairo University,among 60 CVS patients,and the sample was randomly assigned through a coin to allocate subjects to study or control group(30 for each group).Auditory stimulation techniques were applied three times per week for the study group for two consecutive *** in the control group received only routine hospital care during the study *** Glasgow Coma Scale(GCS)score for assessing the neurological function and level of arousal and the auditory subscale score of Western Neuro Sensory Stimulation Profile(WNSSP)for assessing auditory response were recorded and compared between the two groups before and after the ***:There were statistically significant differences between the study group and the control group regarding third reading of GCS score(11.5±0.3 vs.10.6±0.9,t=4.676,P=0.000).The scores of all auditory subscales of WNSSP in the study groups increased after implementing the auditory stimulation protocol(P<0.05).Conclusion:Utilizing the auditory stimulation protocol by nurse proves to be an effective method for enhancing hearing responses in individuals with CVS.

关键词： Auditory stimulation techniques hearing response nursing management stroke

Nanothermite colloids: A new prospective for enhanced performance

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Defence Technology（防务技术） 2019年第3期15卷 319-325页

作者： M. Gaber zaky ahmed M. Abdalla Rakesh P. Sahu Ishwar K. Puri Mostafa Radwan Sherif Elbasuney School of Chemical Engineering Military Technical College Kobry Elkoba Cairo Egypt Department of Engineering Physics and Department of Mechanical Engineering McMaster University 1280 Main Street West Hamilton Ontario L8S 4L7 Canada Department of Mechanical Engineering McMaster University 1280 Main Street West Hamilton Ontario L8S 4L7 Canada British University in Egypt Elshorouk City Cairo Egypt

Nanothermites (metal oxide/metal) can offer tremendously exothermic self sustained reactions. CuO is one of the most effective oxidizers for naonothermite applications. This study reports on two prospectives for the manufacture of CuO nanoparticles. Colloidal CuO particles of 15 nm particle size were developed using hydrothermal synthesis technique. Multiwalled carbon nanotubes (MWCNTs) with surface are 700m2/g was employed as a substrate for synthesis of CuO-coated MWCNTs using electroless plating. On the other hand, aluminium particles with combustion heat of 32000 J/g is of interest as high energy density material. The impact of stoichiometric nanothermite particles (CuO/Al & Cuo-coated MWCNTs/Al) on shock wave strength of Al/TNT nanocomposite was evaluated using ballistic mortar test. While CuO-coated MWCNTs decreased the shock wave strength by 15%;colloidal CuO enhanced the shock wave strength by 30%. The superior performance of colloidal CuO particles was correlated to their steric stabilization with employed organic solvent. This is the first time ever to report on fabrication, isolation, and integration of stablilized colloidal nanothermite particles into energetic matrix where intimate mixing between oxidizer and metal fuel could be achieved.

关键词： Hydrothermal synthesis Nanoparticles Carbon nanotubes Nanothermites Energetic materials

COVID-19-induced transaminitis and hyperbilirubinemia:Presentation and outcomes

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World Journal of Gastroenterology 2023年第7期29卷 1123-1130页

作者： Zeinab Nabil ahmed Said Safinaz Adel El Habashy Samy zaky ESCMID Study Group for Viral Hepatitis Department of Medical Microbiology and Immunology Faculty of Medicine(For Girls)Al-Azhar UniversityCairo 11754Nasr CityEgypt Department of Pediatrics Ain Shams UniversityCairo 11391AbbaseiaEgypt Department of Hepato-gastroenterology and Infectious Diseases Faculty of Medicine(For Girls)Al-Azhar UniversityCairo 11754Egypt 不详

The risk of liver injury in patients with coronavirus disease 2019(COVID-19)infection is quite ***,liver function test abnormalities are still detected in COVID-19 patients despite the development of antivirals and the availability of several types of *** editorial describes liver involvement during COVID-19 infection in patients with or without preexisting liver injury,such as chronic liver disease,to elucidate COVID-19-induced liver function abnormalities and their severity,pathophysiology,clinical manifestations,and clinical and laboratory *** also discuss the effect of vaccination against COVID-19 to better understand host factors,such as age,gender,and race,on the incidence and severity of liver dysfunction at initial presentation and during the ***,we summarize the results of relevant meta-analyses published to date and highlight the importance of adequate liver function monitoring in the current climate of the overwhelming COVID-19 pandemic.

关键词： COVID-19 SARS-CoV-2 Liver injury Transaminases Hyperbilirubinemia Pathophysiology

The medicinal chemistry of Urtica dioica L.:from preliminary evidence to clinical studies supporting its neuroprotective activity

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Natural Products and Bioprospecting 2023年第1期13卷 585-595页

作者： Prabhakar Semwal Abdur Rauf ahmed Olatunde Pooja Singh Mohamed Y.zaky Md.Mozahidul Islam Anees ahmed Khalil Abdullah S.M.Aljohani Waleed Al Abdulmonem Giovanni Ribaudo Department of Biotechnology Graphic Era Deemed to be University566/6 Bell RoadClement TownDehra DunIndia Department of Chemistry University of SwabiSwabiPakistan Department of Medical Biochemistry Abubakar Tafawa Balewa UniversityBauchiNigeria Molecular Physiology Division Faculty of ScienceBeni-Suef UniversityBeni-SuefEgypt Oncology Division Department of Biomedical and Clinical ScienceFaculty of MedicineLinköping UniversityLinköpingSweden Department of Environmental Management SESMIndependent UniversityBangladeshBashundhara R/ADhakaBang-ladesh University Institute of Diet and Nutritional Sciences Faculty of Allied Health SciencesThe University of LahoreLahorePakistan Department of Veterinary Medicine College of Agriculture and Veterinary MedicineQassim UniversityBuraydahSaudi Arabia Department of Pathology College of Med-icineQassim UniversityBuraydahSaudi Arabia Department of Molecular and Translational Medicine University of BresciaBresciaItaly

Urtica dioica is a perennial herb from the family of Urticaceae that is commonly known as stinging *** plant is widespread in Europe,Africa,America,and a part of Asia,as it adapts to different environments and climatic *** leaves,stalk,and bark of *** found applications in the field of nutrition,cosmetics,textile,pest control and *** this connection,bioactive chemical constituents such as flavonoids,phenolic acids,amino acids,carotenoids,and fatty acids have been isolated from the *** this review,we aim at providing an updated and comprehensive overview of the contributions in literature reporting computational,in vitro,pre-clinical and clini-cal data supporting the therapeutic applications of *** evidence shows that *** constituents and extracts can provide neuroprotective effects by acting through a combination of different molecular mecha-nisms,that are discussed in the *** findings could lay the basis for the identification and design of more effective tools against neurodegenerative diseases.

关键词： Urtica dioica Neuroprotection Natural compounds Flavonoids Medicinal chemistry

Oral Vinorelbine as Switch Maintenance Therapy versus Best Supportive Care in Patients with Advanced Adenocarcinoma Non-Small Cell Lung Cancer EGFR Wild Type

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Journal of Cancer Therapy 2019年第12期10卷 908-914页

作者： Amen Hamdy zaky ahmed Refaat Abd Elzaher Ola Nabih Medical Oncology Department South Egypt Cancer Institute Assuit University Assuit Egypt Clinical Oncology Department Faculty of Medicine Assuit University Assuit Egypt

Background: This study was performed to evaluate the efficacy and safety of switch maintenance therapy with oral vinorelbine in advanced non-small cell lung cancer (NSCLC) with adenocarcinoma limited to epidermal growth factor receptor (EGFR) wild type. Materials and Methods: In this single randomized trial, patients with advanced stage (IIIB and IV) NSCLC with adenocarcinoma EGFR wild-type status, treated with 6 cycles of platinum based chemotherapy. Patients did not show progression after first-line chemotherapy were randomly assigned to receive switch maintenance with vinorelbine (80 mg/m2, day 1, 8) (group I) or the best supportive care until disease progression (group II). Results: The median progression free survival (PFS) was 9.7 months for group I versus 5.7 months for group II with statistically significant difference between both groups [HR = 1.15;95% CI 1.19 to 1.49;P value = 0.002], while the median overall survival (OS) was 13.2 months for group I versus 11.9 months for group II with no statistically significant differences between both groups [HR = 1.24;95% CI 1.05 to 1.46;P value = 0. 3]. The patients who received oral vinorelbine had tolerable toxicity profile. Conclusion: Switch maintenance therapy with oral vinorelbine, though improve PFS, did not improve OS in patients with NSCLC with adenocarcinoma EGFR wild type.

关键词： Lung Cancer Maintenance Chemotherapy Vinorelbine EGFR-Wild Type