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Role of macroscopic on-site evaluation of endoscopic ultrasoundguided fine-needle aspiration/biopsy:Results of a multicentric prospective study

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World Journal of Gastrointestinal Endoscopy 2024年第11期16卷 595-606页

作者： hussein h Okasha hiwa A hussein Khaled M Ragab Omar Abdallah Fedoua Rouibaa Borahma Mohamed Fahd Ghalim Mahmoud Farouk Mohamed Lasheen Mohamed A elbasiony ahmed E Alzamzamy ahmed el Deeb hassan Atalla Mahmoud el-Ansary Sahar Mohamed Moaz elshair Wafaa Khannoussi Mohamed Z Abu-Amer Amine elmekkaoui Mohammed S Naguib Adil Ait Errami ahmed el-Meligui ahmed h el-habashi Mahmoud G Ameen Dalia Abdelfatah Mona Kaddah hanane Delsa Division of Gastroenterology and hepatology Department of Internal MedicineKasr Al-Aini School of MedicineCairo UniversityCairo 11562Egypt Sulaimani Center for Advanced Gastrointestinal Endoscopy Sulaimani College of MedicineSulaymaniyah 46001Iraq Department of hepatology and Gastroenterology Theodor Bilharz Research InstituteCairo 11211Egypt hepatology and Gastroenterology Unit Department of Internal MedicineMansoura UniversityFaculty of MedicineMansoura 35516Egypt Gastrointestinal Endoscopy Center Military Hospital Mohamed VFaculty of Medicine of RabatRabat 10100Rabat-Salé-KénitraMorocco Department of Gastroenterology“C” Ibn Sina HospitalMohammed V University in RabatRabat 10000Rabat-Salé-KénitraMorocco Digestive Endoscopy Unit Mekka ClinicCasablanca 20000Casablanca-SettatMorocco Department of Tropical Medicine and Gastroenterology Luxor UniversityLuxor 85951Egypt hepatology and Gastroenterology Unit Department of Internal MedicineFaculty of MedicineMansoura UniversityMansoura 35516Egypt Department of Gastroenterology and hepatology Maadi Armed Forces Medical ComplexMilitary Medical AcademyCairo 11841Egypt Department of Gastroenterology National Hepatology and Tropical Medicine Research InstituteCairo 12556Egypt Department of hepatology Gastroenterology and Infectious DiseasesFaculty of MedicineAl-Azhar UniversityCairo 11651Egypt Department of Gastroenterology and Endoscopy Center Cheikh Khalifa International University HospitalMohammed VI University of Sciences and HealthCasablanca 82403Casablanca-SettatMorocco Research Unit Mohammed VI Center for Research and InnovationRabat 10100Rabat-Salé-KénitraMorocco Department of hepato-Gastroenterology Hassan II University Hospital of FezFaculty of MedicinePharmacy and Dentistry of FezSidi Mohamed Ben Abdellah UniversityFes 30003Fès-MeknèsMorocco Department of Gastroenterology Ahmed Maher Teaching HospitalCairo 11451Egypt Department of Gastroenterology Cadi Ayyad UniversityMohammed VIth University HospitalMarrakech

BACKGROUND The concept of macroscopic on-site evaluation(MOSE)was introduced in 2015 when the endoscopist observed better diagnostic yield when the macroscopically visible core on MOSE was superior to 4 *** studies suggest that MOSE by the endoscopist may be an excellent alternative to rapid on-site evaluation,and some classi-fications have been *** studies have assessed the adequacy of histologic cores in MOSE during endoscopic ultrasound-guided fine-needle aspiration/biopsy(EUS-FNA/FNB).AIM To evaluate the performance of MOSE during EUS-FNA/*** This multicentric prospective study was conducted in 16 centers in 3 countries(Egypt,Iraq,and Morocco)and included 1108 patients with pancreatic,biliary,or gastrointestinal pathology who were referred for EUS *** prospectively analyzed the MOSE in 1008 patients with available histopathological reports according to 2 classifications to determine the adequacy of the histological core *** management and analysis were performed using a Statistical Package for Social Sciences(SPSS)version *** A total of 1074 solid lesions were biopsied in 1008 patients with available cytopathological *** age was 59 years,and 509 patients(50.5%)were *** mean lesion size was 38 *** most frequently utilized needles were FNB-Franseen(74.5%)and 22 G(93.4%),with a median of 2 *** to 2 classifications,618 non-bloody cores(61.3%)and 964 good samples(95.6%)were adequate for histological *** overall diagnostic yield of cytopathology was 95.5%.The cytological examination confirmed the diagnosis of malignancy in 861 patients(85.4%),while 45 samples(4.5%)were ***-procedural adverse events occurred in 33 patients(3.3%).Statistical analysis showed a difference between needle types(P=0.035)with a high sensitivity of FNB(97%).The analysis of the relationship between the MOSE-score and the final diagnosis showed a significant difference between the different

关键词： Macroscopic on-site evaluation Fine-needle aspiration Fine-needle biopsy Endoscopic ultrasound Specimen

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LEO satellite clock analysis and prediction for positioning applications

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Geo-Spatial Information Science 2022年第1期25卷 14-33页

作者： Kan Wang ahmed el-Mowafy School of Earth and Planetary Sciences Curtin UniversityPerthAustralia

The positioning service aided by low Earth orbit(LEO)mega-constellations has become a hot topic in recent *** achieve precise positioning,accuracy of the LEO clocks is important for single-receiver *** bridge the gap between the applicable time of the clock products and the time of positioning,the precise LEO clocks need to be predicted over a certain period depending on the sampling interval of the clock *** study discusses the prediction errors for periods from 10 s to 1 h for two typical LEO clock types,*** ultra-stable oscillator(USO)and the oven-controlled crystal oscillator(OCXO).The prediction is based on GNSS-determined precise clock estimates,where the clock stability is related to the GNSS estimation errors,the behaviors of the oscillators themselves,the systematic effects related to the environment and the relativistic effects,and the stability of the time *** on real data analysis,LEO clocks of the two different types are simulated under different conditions,and a prediction model considering the systematic effects is *** to a simple polynomial fitting model usually applied,the proposed model can significantly reduce the prediction errors,*** about 40%-70%in simulations and about 5%-30%for real data containing different miss-modeled *** both clock types,short-term prediction of 1 min would result in a root mean square error(RMSE)of a few centimeters when using a very stable time *** RMSE amounts to about 0.1 m,when a typical real-time time reference of the national center for space studies(CNES)real-time clocks was *** long-term prediction of 1 h,the RMSE could range from below 1 m to a few meters for the USOs,depending on the complexity of the miss-modeled *** OCXOs,the 1 h prediction could lead to larger errors with an RMSE of about 10 m.

关键词： LEO clock prediction USO OCXO relativistic effects

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Permutation-substitution image encryption scheme based on a modified chaotic map in transform domain

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Journal of Central South University 2017年第9期24卷 2049-2057页

作者： Ramadan Noha ahmed hossameldin h el-khamy Said E Abd el-Samie Fathi E Faculty of electronic Engineering Menofia University Faculty of Engineering Alexandria University

A new chaotic image encryption scheme based on permutation and substitution in the Fourier domain is *** Fourier Transform(FRFT)is used before the encryption scheme to get a large degree of *** permutation is achieved by Baker map and the substitution by a key-related-to-plain-image algorithm based on the modified Logistic *** of the Logistic map is developed to increase the space of the encryption key,and hence increase the *** key of the encryption algorithm dependents on the plain image,and thus,the cipher image is sensitive to both the initial key and the plain image to resist known-plaintext and chosen plaintext *** key space is large and hence the algorithm can effectively resist brute-force *** proposed scheme is examined using different performance evaluation metrics and the results prove that the proposed scheme is highly secure,and it can effectively resist different attacks.

关键词： Backer map chaotic encryption fractional Fourier transform (FRFT) modified Logistic map

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Impact Assessment and Mitigation Techniques for high Penetration Levels of Renewable Energy Sources in Distribution Networks:Voltage-control Perspective

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Journal of Modern Power Systems and Clean Energy 2022年第2期10卷 450-458页

作者： ahmed S.A.Awad Dave Turcotte Tarek h.M.el-Fouly Natural Resources Canada Can-metENERGYVarennesCanadaon leave from the Electrical Power and Machines DepartmentFaculty of EngineeringAin Shams UniversityCairo 11566Egyp Natural Resources Canada CanmetENERGYVarennesCanada Advanced Power and Energy Center Khalifa UniversityAbu DhabiUnited Arab Emirates

The integration of renewable distributed generation(RDG)into distribution networks is promising and increasing ***,high penetration levels of distributed generation(DG)are often limited as they may have an adverse effect on the operation of distribution *** of the operation challenges is the interaction between DG and voltage-control equipment,e.g.,an under-load tap changer(ULTC),which is basically designed to compensate for voltage changes caused by slow load *** integration of variable DGs leads to rapid voltage fluctuations,which can negatively affect the tap operation of *** paper investigates the impact of high penetration levels of RDG on the tap operation of ULTC in distribution networks through *** mitigation techniques that can alleviate this impact are also *** these techniques,constant power-factor mode is regarded as the best trade-off between the simplicity and effectiveness of minimizing the number of tap *** are performed on a Canadian benchmark rural distribution feeder using OpenDSS software.

关键词： Renewable energy distributed generation(DG) voltage regulator load tap changer distribution network.

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hepatoprotective Effect of Camel Thorn Polyphenols in Concanavalin A-Induced hepatitis in Mice

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Chinese Journal of Integrative Medicine 2024年第12期30卷 1090-1100页

作者： Nageh ahmed el-Mahdy Thanaa ahmed el-Masry ahmed Mahmoud el-Tarahony .Fatemah AAlherz Enass Youssef Osman Department of Pharmacology and Toxicology Faculty of PharmacyTanta UniversityTanta 31527Egypt Department of Pharmaceutical Sciences College of PharmacyPrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia

Objective:To explore the prophylactic and therapeutic effects of Alhagi maurorum ethanolic extract(AME)in concanavalin A(Con A)-induced hepatitis(CIh)as well as possible underlying ***:Polyphenols in AME were characterized using high performance liquid chromatography(hPLC).Swiss albino mice were divided into 4 *** group received intravenous phosphate-buffered saline(PBS);Con A group received 40 mg/kg intravenous Con *** group administered 300 mg/(kg·d)AME orally for 5 days before Con A *** group received intravenous Con A then administered300 mg/kg AME at 30 min and 3 h after Con A *** 24 h of Con A injection,hepatic injury,oxidative stress,and inflammatory mediators were *** examination and markers of apoptosis,inflammation,and CD4^(+)cell infiltration were also ***:hPLC analysis revealed that AME contains abundant polyphenols with pharmacological constituents,such as ellagic acid,gallic acid,ferulic acid,methylgallate,and *** alleviated Con A-induced hepatic injury,as manifested by a significant reduction in alanine aminotransferase,aspartate aminotransferase and alkaline phosphatase(Phe antioxidant effect of AME was revealed by a significant reduction in oxidative stress markers(nitric oxide and malondialdehyde)and restored glutathione(Phe levels of proinflammatory cytokines(tumor necrosis factor-α,interferon-γ,and interleukin-6)and c-Jun N-terminal kinase(JNK)activity were reduced(Phistopathological examination of liver tissue showed that AME significantly ameliorated necrotic and inflammatory lesions induced by Con A(Phe expression of nuclear factor kappa B,pro-apoptotic protein(Bax),caspase-3,and CD4^(+)T cell hepatic infiltration(Phe expression of anti-apoptotic protein Bcl-2 was increased(Phas hepatoprotective and ameliorative effects in CIh mice

关键词： concanavalin A-induced hepatitis Alhagi maurorum ethanolic extract hepatoprotective effect

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Spirulina platensis extract improves the production and defenses of the common bean grown in a heavy metals-contaminated saline soil

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Journal of Environmental Sciences 2023年第7期129卷 240-257页

作者： Mostafa M.Rady ahmed S.elrys Eman Selem ahmed A.A.Mohsen Safaa M.A.I.Arnaout ahmed h.el-Sappah Khaled A.el-Tarabily el-Sayed M.Desoky Botany Department Faculty of AgricultureFayoum UniversityFayoum 63514Egypt College of Tropical Crops Hainan UniversityHaikou 570228China Soil Science Department Faculty of AgricultureZagazig UniversityZagazig 44511Egypt Botany and Microbiology Department Faculty of ScienceZagazig UniversityZagazig 44511Egypt horticulture Department Faculty of AgricultureZagazig UniversityZagazig 44511Egypt Botany Department Faculty of AgricultureZagazig UniversityZagazig 44511Egypt Genetics Department Faculty of AgricultureZagazig UniversityZagazig 44511Egypt Department of Biology College of ScienceUnited Arab Emirates UniversityAl-Ain 15551United Arab Emirates Khalifa Center for Genetic Engineering and Biotechnology United Arab Emirates UniversityAl-Ain 15551United Arab Emirates harry Butler Institute Murdoch UniversityMurdoch 6150Australia

Plants have to cope with several abiotic stresses,including salinity and heavymetals(hMs).Under these stresses,several extracts have been used as effective natural biostimulants,however,the use of Spirulina platensis(SP)extract(SPE)remains *** effects of SPE were evaluated as soil addition(SA)and/or foliar spraying(FS)on antioxidant defenses and hMs content of common bean grown in saline soil contaminated with ***(40 or 80 mg SPE/hill added as SA or 20 or 40 mg SPE/plant added as FS)or integrative(SA+FS)applications of SPE showed significant improvements in the following order:SA-80+FS-40>SA-80+FS-20>SA-40+FS-40>SA-40+FS-20>SA-80>SA-40>FS-40>FS-20>***,the integrative SA+FS with 40 mg SP/plant was the most effective treatment in increasing plant growth and production,overcoming stress effects and minimizing contamination of the edible *** significantly increased plant growth(74%–185%)and yield(107%–227%)by enhancing net photosynthetic rate(78.5%),stomatal conductance(104%),transpiration rate(124%),and contents of carotenoids(60.0%),chlorophylls(49%–51%),and NPK(271%–366%).These results were concurrent with the marked reductions in malondialdehyde(61.6%),hydrogen peroxide(42.2%),nickel(91%–94%),lead(80%–9%),and cadmium(74%–91%)contents due to the improved contents of glutathione(87.1%),ascorbate(37.0%),andα-tocopherol(77.2%),and the activities of catalase(18.1%),ascorbate peroxidase(18.3%),superoxide dismutase(192%),and glutathione reductase(52.2%)as reinforcing ***,this most effective treatment is recommended to mitigate the stress effects of salinity and hMs on common bean production while minimizing hMs in the edible part.

关键词： Antioxidant defense system Biostimulants heavy metals Microalgae extracts Saline soil Soil pollution

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Thomson and rotation effects during photothermal excitation process in magnetic semiconductor medium using variable thermal conductivity

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Applied Mathematics and Mechanics(English Edition) 2020年第6期41卷 909-926页

作者： K.LOTFY A.K.KhAMIS A.A.el-BARY M.h.ahmed Department of Mathematics Faculty of ScienceZagazig UniversityZagazig 44519Egypt Department of Mathematics Faculty of ScienceTaibah UniversityAl-Madinah 30002Saudi Arabia Department of Mathematics Faculty of ScienceNorthern Border UniversityArar 91431Saudi Arabia Arab Academy for Science Technology and Maritime TransportAlexandria 1029Egypt

This study investigates a strong magnetic field acting over an elastic rotator semiconductor *** Thomson effect due to the magnetic field during the photothermal transport process is studied,and the thermoelectricity theory is used to explain the behavior of waves in the homogenous and isotropic medium under the effect of variable thermal *** variable thermal conductivity is considered as a linear function of the *** two-dimensional deformation equations are used to describe the overlaps among plasma,electrical,thermal,and magneto-elastic *** charge density of inertia-particles is considered as a function of time for studying the induced electric *** normal mode analysis is used to obtain the exact solutions of the physical field distributions as part of this *** obtain the complete solutions of the physical field quantities,the certain mechanical loads,electromagnetic effects,thermal effects,and plasma recombination process are applied *** results of the physical distributions are graphically depicted and discussed in consideration of the internal heat source,rotation,and Peltier coefficient.

关键词： photothermal thermal conductivity Thomson effect rotation magnetic field Peltier coefficient

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Enhancing asphaltene precipitation modeling by cubic-PR solid model using thermodynamic correlations and averaging techniques

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Petroleum Science 2020年第1期17卷 232-241页

作者： Aktham E.Shoukry ahmed h.el-Banbi helmy Sayyouh Petroleum Engineering University of WyomingLaramieWYUSA Petroleum Department Faculty of EngineeringCairo UniversityGizaEgypt Petroleum Engineering American University in Cairo(AUC)GizaEgypt

Cubic equation-of-state solid models are one of the most widely used models to predict asphaltene precipitation *** parameters are needed to model precipitation under different pressures and temperatures and are usually obtained through tuning with multi asphaltene onset *** the purpose of enhancing the cubic Peng–Robinson solid model and reducing its dependency on asphaltene experiments,this paper tests the use of aromatics and waxes correlations to obtain these thermodynamic *** addition,weighted averages between both correlations are *** averaging is based on reported saturates,aromatics,resins,asphaltene(SARA)fractions,and wax *** the methods are tested on four oil samples,with previously published data,covering precipitation and onset *** proposed wax-asphaltene average showed the best match with experimental data,followed by a SARA-weighted *** new addition enhances the model predictability and agrees with the general molecular structure of asphaltene molecules.

关键词： Asphaltene precipitation Asphaltene onset pressure Asphaltene precipitation modeling Asphaltene thermodynamics Cubic equation of state

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Plant phosphatidylinositol-specific phospholipase C at the center of plant innate immunity

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Journal of Integrative Plant Biology 2017年第3期59卷 164-179页

作者： ahmed M.Abd-el-haliem Matthieu h.A.J.Joosten Laboratory of Phytopathology Wageningen University Droevendaalsesteeg 1 6708 PB Wageningen The Netherlands Plant Physiology Swammerdam Institute for Life Sciences University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands

Understanding plant resistance to pathogenic microbes requires detailed information on the molecular mechanisms controlling the execution of plant innate immune responses. A growing body of evidence places phosphoinositide-specific phospholipase C （PI-PLC） en- zymes immediately downstream of activated immune receptors, well upstream of the initiation of early defense responses. An increase of the cytoplasmic levels of free Ca2＋, lowering of the intercellular ph and the oxidative burst are a few examples of such responses and these areregulated by PI-PLCs. Consequently, PI-PLC activation represents an early primary signaling switch between elicitation and response involving the controlled hydrolysis of essential signaling phospholipids, thereby simulta- neously generating lipid and non-lipid second messenger molecules required for a swift cellular defense response. here, we elaborate on the signals generated by PI-PLCs and their respective downstream effects, while providing an inventory of different types of evidence describing the involvement of PI-PLCs in various aspects of plant immunity. We project the discussed information into a model describing the cellular events occurring after the activation of plant immune receptors. With this review we aim to provide new insights supporting future research on plant PI-PLCs and the development of plants with improved resistance.

关键词： Pradeep Kachroo University of Kentucky USA

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Magnetic field induction and magnetic force distribution profiles in plasma focus discharge device

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Plasma Science and Technology 2021年第7期23卷 110-120页

作者： A A LAShIN T M ALLAM h A el-SAYED Kamal M ahmed S A WARD h M SOLIMANand M A ABOUelATTA Plasma and Nuclear Fusion Department Nuclear Research CentreEgyptian Atomic Energy AuthorityInshas 13759Egypt Faculty of Engineering Delta University for Science and TechnologyGamasa 11152Egypt electrical Engineering Department Faculty of Engineering at ShoubraBenha UniversityCairo 11629Egypt

We report a simple-to-perform technique to investigate the distribution of the azimuthal magnetic field induction,Bθ,and the induced magnetic force acting on the plasma current sheath(PCS)in a plasma focus(PF)*** in situ measurement technique can undoubtedly be beneficial when other fast-imaging techniques are not *** are not *** work was conducted in the low-energy Mather-type EAEA-PF1 device operated in *** axial distribution(Bθ)z along the coaxial electrodes system was measured with a four magnetic-probe set technique at different radial distances(r=2.625×10^(−2) to 4.125×10^(−2) m)within the annular space between the coaxial electrodes during the 1st and 2nd half cycles of the discharge current waveform,where inner electrode of coaxial electrode system has a+ve polarity and−ve polarity,***,radial and total magnetic force distribution profiles were estimated from Bθ*** of PCS shape in terms of its inclination(curvature)angle,θ,along the axial rundown phase and the correlation between the magnetic forces per unit volume acting on the PCS,the inclination angleθof the PCS,and the formation of a powerful PF action during the 1st and 2nd half cycles is carried *** of inclination angle,θ,on total magnetic force per unit volume acting on PCS axial motion was studied,separately,during the 1st and 2nd half cycles.

关键词： plasma focus azimuthal magnetic field magnetic force inclination angle plasma current sheath

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