Plant phosphatidylinositol-specific phospholipase C at the center of plant innate immunity

作     者：Ahmed M.Abd-El-Haliem Matthieu H.A.J.Joosten 

作者机构：Laboratory of Phytopathology Wageningen University Droevendaalsesteeg 1 6708 PB Wageningen The Netherlands Plant Physiology Swammerdam Institute for Life Sciences University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands 

出 版 物：《Journal of Integrative Plant Biology》 (植物学报（英文版）)

年 卷 期：2017年第59卷第3期

页      面：164-179页

核心收录：

学科分类：0710[理学-生物学] 09[农学] 0904[农学-植物保护] 0901[农学-作物学] 0703[理学-化学] 090401[农学-植物病理学] 0902[农学-园艺学] 

基　　金：funding by The Netherlands Organization for Scientific Research (NWO)  Earth and Life Sciences (ALW)  in the form of Mosaic grant 017.003.046 

主　　题：Pradeep Kachroo University of Kentucky USA 

摘      要：Understanding plant resistance to pathogenic microbes requires detailed information on the molecular mechanisms controlling the execution of plant innate immune responses. A growing body of evidence places phosphoinositide-specific phospholipase C （PI-PLC） en- zymes immediately downstream of activated immune receptors, well upstream of the initiation of early defense responses. An increase of the cytoplasmic levels of free Ca2＋, lowering of the intercellular pH and the oxidative burst are a few examples of such responses and these areregulated by PI-PLCs. Consequently, PI-PLC activation represents an early primary signaling switch between elicitation and response involving the controlled hydrolysis of essential signaling phospholipids, thereby simulta- neously generating lipid and non-lipid second messenger molecules required for a swift cellular defense response. Here, we elaborate on the signals generated by PI-PLCs and their respective downstream effects, while providing an inventory of different types of evidence describing the involvement of PI-PLCs in various aspects of plant immunity. We project the discussed information into a model describing the cellular events occurring after the activation of plant immune receptors. With this review we aim to provide new insights supporting future research on plant PI-PLCs and the development of plants with improved resistance.