检索结果-南通市图书馆

Does steroid-free immunosuppression improve the outcome in kidney transplant recipients compared to conventional protocols?

引用

World Journal of Transplantation 2021年第4期11卷 99-113页

作者： ahmed aref Ajay Sharma ahmed Halawa Department of Nephrology Sur hospitalSur 411Oman Department of Transplantation Royal Liverpool University HospitalsLiverpool 111United Kingdom Department of Transplantation Sheffield Teaching HospitalsSheffield S57AUUnited Kingdom

Steroids continue to be the cornerstone of immune suppression since the early days of organ *** are key component of induction protocols,maintenance therapy and in the treatment of various forms of *** steroid use resulted in significant side effects on almost all the body organs owing to the presence of steroid receptors in most of the mammalian *** allograft recipients had to accept the short and long term complications of steroids because of lack of effective *** situation changed with the introduction of newer and more effective immune suppression agents with a relatively more acceptable side effect *** a result,the clinicians have been contemplating if it is the time to abandon the unquestionable reliance on maintenance steroids in modern transplantation *** review aims to evaluate the safety and efficacy of various steroid-minimization approaches(steroid avoidance,early steroid withdrawal,and late steroid withdrawal)in kidney transplant recipients.A meticulous electronic search was conducted through the available data resources like SCOPUS,MEDLINE,and Liverpool University library *** articles obtained through our search were included.A total number of 90 articles were eligible to be included in this review[34 randomised controlled trials(RCT)and 56 articles of other research modalities].All articles were evaluating the safety and efficacy of various steroidfree approaches in comparison to maintenance *** will cover only the RCT articles in this *** used in right clinical context,steroid-free protocols proved to be comparable to steroid-based maintenance *** appropriate approach should be tailored individually according to each recipient immunological challenges and clinical condition.

关键词： Kidney transplantation Steroid free Immune suppression Steroid avoidance Steroid withdrawal Outcome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pancreatic transplantation: Brief review of the current evidence

引用

World Journal of Transplantation 2019年第4期9卷 81-93页

作者： ahmed aref Tariq Zayan Ravi Pararajasingam Ajay Sharma ahmed Halawa Department of Nephrology Sur HospitalSur 411Oman Faculty of Health and Science Institute of Learning and TeachingUniversity of LiverpoolLiverpool L69 3GBUnited Kingdom Department of Transplantation Sheffield Teaching HospitalsSheffield S5 7AUUnited Kingdom Renal Medicine Royal Liverpool University HospitalsLiverpool L7 8XPUnited Kingdom Department of Transplantation Surgery Sheffield Teaching HospitalsSheffield S5 7AUUnited Kingdom

Kidney transplantation is the treatment of choice for management of end-stage renal ***,in diabetic patients,the underlying metabolic disturbance will persist and even may get worse after isolated kidney *** transplantation in humans was first introduced in *** initial outcome was ***,this was changed after the improvement of surgical techniques together with better patient selection and the availability of potent and better-tolerated immune-suppression like cyclosporine and induction *** kidney and pancreas transplantation will not only solve the problem of organ failure,but it will also stabilise or even reverse the metabolic complications of *** kidney and pancreas transplantation have the best long term outcome in diabetic cases with renal ***,at the cost of an initial increase in morbidity and risk of *** transplantation options include pancreas after kidney transplantation and islet cell *** aim by this work to explore various options which can be offered to a diabetic patient with advanced chronic kidney *** work will provide a simplified,yet up-to-date information regarding the different management options for those diabetic chronic kidney failure patients.

关键词： Combined kidney pancrease transplantation Renal transplantation Diabetic kidney disease Diabetes mellitus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Smoking in Renal Transplantation; Facts Beyond Myth

引用

World Journal of Transplantation 2017年第2期7卷 129-133页

作者： ahmed aref Ajay Sharma ahmed Halawa Department of Nephrology Sur hospital Faculty of Health and Science Institute of Learning and TeachingUniversity of Liverpool Royal Liverpool University Hospital Liverpool L7 8XPUnited Kingdom

Smoking is one of the preventable leading causes of death worldwide. Most of the studies focused on the association between smoking and cardiovascular disease, pulmonary diseases, malignancy and death. However, the direct effect of smoking on the renal system was undermind. There are emerging evidence correlating tobacco use with pathological changes in the normal kidneys. The effect is more obvious on the renal allograft most probably due to the chronic immune suppression status and the metabolic effect of the drugs. Several studies have documented a deleterious effect of smoking on the renal transplant recipients. Smoking was associated with lowering patient and graft survival. Smoking cessation proved to improve graft survival and to a lesser extent recipient survival. Even receiving a renal transplant from a smoker donor increases the risk of death for the recipient and carries a poorer graft survival compared to non-smoking donors. Most of the studies investigating the effect of smoking were based on self-reporting questioners, which may be misleading due to poor recall or the desire to give socially acceptable answers. This made the need of a reliable biomarker of ultimate importance. Cotinine was proposed as a promising biomarker that may help to provide objective evidence regarding the status of smoking and the dose of nicotine exposure, yet there are still some limitations of its use. The aim of this work is to review the current evidence to improve our understanding of this critical topic. Indeed, this will help to guide better-designed studies in the future.

关键词： smoking kidney donor kidney recipient renal transplantation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Utility of central venous pressure measurement in renal transplantation: Is it evidence based?

引用

World Journal of Transplantation 2018年第3期8卷 61-67页

作者： ahmed aref Tariq Zayan Ajay Sharma ahmed Halawa Department of Nephrology Sur hospital Faculty of Health and Science Institute of Learning and Teaching University of Liverpool Department of Transplantation Surgery Royal Liverpool University Hospital Department of Transplantation Surgery Sheffield Teaching Hospitals

Adequate intravenous fluid therapy is essential in renal transplant recipients to ensure a good allograft perfusion. Central venous pressure(CVP) has been cons-idered the corners-tone to guide the fluid therapy for decades; it was the only available simple tool worldwide. However, the revolutionary advances in assessing the dynamic preload variables together with the availability of new equipment to precisely measure the effect of intravenous fluids on the cardiac output had created a question mark on the future role of CVP. Des-pite the critical role of fluid therapy in the field of tra-nsplantation. There are only a few clinical studies that compared the CVP guided fluid therapy with the other modern techniques and their relation to the outcome in renal transplantation. Our work sheds some light on the available published data in renal transplantation, together with data from other disciplines evaluating the utility of central venous pressure measurement. Although lager well-designed studies are still required to consolidate the role of new techniques in the field of renal transplantation, we can confidently declare that the new techniques have the advantages of providing more accurate haemodynamic assessment, which results in a better patient outcome.

关键词： Fluid monitoring Central venous pressure Renal transplantation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Consecutive narrow and broad quasi-periodic fast-propagating wave trains associated with a flare

引用

Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 200-211页

作者： Xinping Zhou Yuandeng Shen Chengrui Zhou Zehao Tang ahmed ahmed Ibrahim College of Physics and Electronic Engineering Sichuan Normal UniversityChengdu 610068China State Key Laboratory of Space Weather Chinese Academy of SciencesBeijing 100190China Yunnan Observatories Chinese Academy of SciencesKunming 650216China Department of Physics and Astronomy College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Saudi Arabia

The excitation mechanism of coronal quasi-period fast-propagating(QFP)wave trains remains *** Atmospheric Imaging Assembly onboard the Solar Dynamics Observatory observations,we study a narrow and a broad QFP wave trains excited one after another during the successive eruptions of filaments hosted within a fan-spine magnetic system on October 20,*** consecutive occurrence of these two types of QFP wave trains in the same event provides an excellent opportunity to explore their excitation mechanisms and compare their physical *** observational results reveal that narrow and broad QFP wave trains exhibit distinct speeds,periods,energy fluxes,and relative intensity amplitudes,although originating from the same active region and being associated with the same GOES C2.9 *** wavelet analysis,we find that the narrow QFP wave train shares a similar period with the flare itself,suggesting its possible excitation through the pulsed energy release in the magnetic reconnection process that generated the accompanying *** the other hand,the broad QFP wave train appears to be associated with the energy pulses released by the successive expansion and unwinding of filament ***,it is plausible that the broad QFP wave train was also excited by the sequential stretching of closed magnetic field lines driven by the erupting *** findings shed light on the different excitation mechanisms and origins of the QFP wave trains.

关键词： narrow wave excitation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study of scalar particles through the Klein–Gordon equation under rainbow gravity effects in Bonnor–Melvin-Lambda space-time

引用

Communications in Theoretical Physics 2024年第4期76卷 113-125页

作者： Faizuddin ahmed Abdelmalek Bouzenada Department of Physics University of Science&Technology MeghalayaRi-Bhoi793101India Laboratory of theoretical and applied Physics Echahid Cheikh Larbi Tebessi UniversityAlgeria

In our investigation,we explore the quantum dynamics of charge-free scalar particles through the Klein–Gordon equation within the framework of rainbow gravity,considering the Bonnor–Melvin-Lambda(BML)space-time *** BML solution is characterized by the magnetic field strength along the axis of the symmetry direction which is related to the cosmological constantΛand the topological parameterαof the *** behavior of charge-free scalar particles described by the Klein–Gordon equation is investigated,utilizing two sets of rainbow functions:(i)f(χ)=■,h(χ)=1 and(ii)f(χ)=1,h(χ)=1+βХ/*** 0<(Х=■)≤1 with E representing the particle's energy,Ep is the Planck's energy,andβis the rainbow *** obtain the approximate analytical solutions for the scalar particles and conduct a thorough analysis of the obtained ***,we study the quantum dynamics of quantum oscillator fields within this BML space-time,employing the Klein–Gordon *** also,we choose the same sets of rainbow functions and obtain the approximate eigenvalue solution for the oscillator ***,we demonstrate that the relativistic approximate energy profiles of charge-free scalar particles and oscillator fields get influenced by the topology of the geometry and the cosmological ***,we show that the energy profiles of scalar particles receive modifications from the rainbow parameter and the quantum oscillator fields by both the rainbow parameter and the frequency of oscillation.

关键词： quantum fields in curved space-time relativistic wave equations solutions of wave equations bound-state special functions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Application of Synthetic Iron Oxyhydroxide with Influencing Factors for Removal of As(Ⅴ) and As(Ⅲ) from Groundwater

引用

Journal of Earth Science 2024年第3期35卷 998-1009页

作者： Shakeel ahmed Talpur Muhammad Yousuf Jat Baloch Chunli Su Javed Iqbal Aziz ahmed Hafeez ahmed Talpur School of Environmental Studies China University of GeosciencesWuhan 430078China DiSPUTer Department of PsychologicalHealth and Territory SciencesUniversity“G.d′Annunzio”Chieti-Pescara66100 ChietiItaly College of New Energy and Environment Jilin UniversityChangchun 130021China School of Plant Environment and Soil SciencesLouisiana State University Agricultural CentreBaton Rouge LA 70803USA Department od Engineering and Geology University“G.d′Annunzio”Chieti-Pescara66100 ChietiItaly

Synthesized iron oxyhydroxide was applied for the adsorptive removal of As(V)and As(III)from the aquas ***,this investigation highlighted the synergistic effect of calcium carbonate in conjunction with iron oxyhydroxide,resulting in enhanced removal *** experiment was conducted under various conditions:concentration,dosage,pH,agitation,and *** characterizations such as Brunauer Emmett Teller,X-ray diffraction,scanning electron microscopy,and Fourier transform infrared spectroscopy were implied to understand adsorption *** Langmuir model revealed optimal concentrations for As(V)=500μg/L at pH-5 and As(III)=200μg/L at pH-7,resulting in 95%and 93%adsorption efficiencies,*** adsorption capacities“qm”were found to be 1266.943μg/g for As(V)and 1080.241μg/g for As(III).Freundlich model demonstrated favorable adsorption by indicating“n>1”such as As(V)=2.542 and As(III)=2.707;similarly,the speciation factor“RL<1”for both species as As(V)=0.1 and As(III)=0.5,*** kinetic study presented a pseudo-second-order model as best fitted,indicating throughout chemisorption processes for removing As(V)and As(III).Furthermore,incorporating calcium carbonate presented a significant leap in the removal efficiency,indicating As(V)from 95%to 98%and As(III)from 93%to 96%,*** findings offer profound motivation for developing effective and sustainable solutions to tackle arsenic contamination,underscoring the exceptional promise of iron oxyhydroxide in conjunction with calcium carbonate to achieve maximum removal efficiency.

关键词： adsorption arsenic As(V) As(III) iron oxyhydroxide isotherms kinetics groundwater.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Topological defects on solutions of the non-relativistic equation for extended double ring-shaped potential

引用

Communications in Theoretical Physics 2024年第8期76卷 29-43页

作者： Badredine Boudjedaa Faizuddin ahmed Natural Sciences and Materials Laboratory University Center Abdelhafid BoussoufMilaAlgeria Department of Mathematics Institute of Mathematics and Computer ScienceUniversity Center Abdelhafid BoussoufMilaAlgeria Department of Physics University of Science&Technology MeghalayaRi-Bhoi793101India

In this study, we focus into the non-relativistic wave equation described by the Schrodinger equation, specifically considering angular-dependent potentials within the context of a topological defect background generated by a cosmic string. Our primary goal is to explore quasi-exactly solvable problems by introducing an extended ring-shaped potential. We utilize the Bethe ansatz method to determine the angular solutions, while the radial solutions are obtained using special functions. Our findings demonstrate that the eigenvalue solutions of quantum particles are intricately influenced by the presence of the topological defect of the cosmic string,resulting in significant modifications compared to those in a flat space background. The existence of the topological defect induces alterations in the energy spectra, disrupting ***, we extend our analysis to study the same problem in the presence of a ring-shaped potential against the background of another topological defect geometry known as a point-like global monopole. Following a similar procedure, we obtain the eigenvalue solutions and analyze the results. Remarkably, we observe that the presence of a global monopole leads to a decrease in the energy levels compared to the flat space results. In both cases, we conduct a thorough numerical analysis to validate our findings.

关键词： non-relativistic wave-equation:Schrödinger equation topological defect:cosmic string point-like global monopole potential:extended ring-shaped potentials Bethe ansatz method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Exact and heuristic formulae to compute the geodetic height from the ellipse equation

引用

Geodesy and Geodynamics 2024年第2期15卷 150-155页

作者： Mohamed Eleiche ahmed Hamdi Mansi Construction Department Faculty of EngineeringEgyptian Russian UniversityCairoEgypt Istituto Nazionale di Geofisica e Vulcanologia Sezione di PisaPisaPlItaly

The conversion of the cartesian coordinates of a point to its geodetic equivalent coordinates in reference to the geodetic ellipsoid is one of the main challenges in *** ellipse equation in the meridian plane significantly influences the value of the geodetic *** research analyzes this influence and how it can contribute to their *** study investigates the mathematical relation between them and presents an exact formula relating to the geodetic height and the ellipse *** addition,a heuristic formula for the relation between the geodetic height and the ellipse equation is proposed,which is independent of the geodetic latitude and has a relative accuracy better than 99.9 %.The calculation is stable,and the cost is low.

关键词： Ellipse equation Geodetic height Heuristic geodetic height

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sustainable bio-energy generation via the conversion of spent wash using dual chamber microbial fuel cell

引用

Waste Disposal and Sustainable Energy 2024年第2期6卷 219-231页

作者： Abdul Sattar Jatoi Jawad ahmed Afaque ahmed Bhutto Muhammad Shuaib Shaikh Department of Chemical Engineering Dawood University of Engineering and Technology KarachiSindhPakistan Changzhou DUBO Polymer Co. Ltd.Changzhou 213002China Department of Basic Science and Related Studies The University of LarkanoSindhPakistan Department of Chemical Engineering Mehran University of Engineering and Technology JamshoroSindhPakistan

Microbial fuel cells(MFCs)are innovative devices that combine microbial processes with electrochemical reactions to convert organic matter in wastewater into electricity while simultaneously treating the *** such application is the treatment of spent wash,a highly polluting effluent generated from the distillery industry after crude mesh is separated into ethanol and spent *** wash,also known as distillery effluent or stillage,is a highly challenging wastewater treatment method due to its high chemical oxygen demand(COD),biological oxygen demand(BOD),and total dissolved solids(TDS).These characteristics make it a complex and polluting industrial effluent that requires specialized treatment processes to reduce its environmental impact ***,MFCs have shown promise in treating spent wash,as they can utilize the organic matter in wastewater as a fuel source for microbial growth as well as for electricity *** the treatment of spent wash,Saccharomyces cerevisiae *** used as a biocatalyst along with 340 mol/L potassium ferricyanide in the cathode chamber and 170 mol/L methylene blue in the anode as a *** tests were conducted by balancing a one-liter volume for power production from spent wash in MFC with the optimal conditions of 10%agarose,pH 8.5,300 mL/min of aeration in the cathode chamber,and 40%(in weight)substrate *** an ideal concentration,the maximum current and power density are roughly 53.41 mA/m^(2)and 72.22 mW/m^(2),*** each litre of processed spent wash,a maximum voltage of 850 mV(4.5 mA)was ***,91%of COD and BOD were removed from the effluent *** findings show that MFCs are capable of producing electricity and efficiently removing COD from wasted wash at the same time.

关键词： Microbial fuel cell Chemical oxygen demand Biological oxygen demand-Current density Power density Spent wash

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：