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Sol-gel synthesis,properties a.d protein loa.ing/delivery ca.a.ity of hollow bioa.tive gla.s na.ospheres with la.ge hollow ca.ity a.d mesoporous shell

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Frontiers of Ma.eria.s Science 2022年第3期16卷 145-157页

作者： ahmed el-FIQI Gla.s Resea.ch Depa.tment National Research CentreCairo 12622Egypt

Hollow na.ospheres exhibit unique properties a.d find a.wide interest in severa. potentia. a.plica.ions such a. drug ***,novel hollow bioa.tive gla.s na.ospheres(HBGn)with la.ge hollow ca.ity a.d la.ge mesopores in their outer shells were synthesized by a.simple a.d fa.ile one-pot ultra.ound a.sisted sol-gel method using PEG a. the core ***,the produced HBGn exhibited la.ge hollow ca.ity with ~43 nm in dia.eter a.d mesoporous shell of ~37 nm in thickness a.d 7 nm pore size a.ong with na.osphere size a.ound 117 *** confirmed the presence of Si a.d Ca.elements a. the surfa.e of the HBGn outer ***,HBGn showed high protein loa.ing ca.a.ity(~570 mg of Cyto c per 1 g of HBGn)in a.dition to controlled protein relea.e over 5 *** a.so demonstra.ed a.good in vitro ca.a.ility of relea.ing ca.cium(Ca.(2+):170 ppm)a.d silica.e(SiO_(4)^(4-):78 ppm)ions in a. a.ueous medium over 2 weeks under physiologica.-like *** in vitro growth of bone-like hydroxya.a.ite na.ocrysta.s wa. exhibited by HBGn during the soa.ing in SBF.a.possible underlying mecha.ism involving the forma.ion of spherica. a.grega.es(coils)of PEG wa. proposed for the forma.ion process of HBGn.

关键词： bioa.tive gla.s hollow na.osphere hollow ca.ity mesoporous shell soft-templa.e ultra.ound a.sisted sol-gel synthesis thera.eutic protein delivery

Na.osecond pulse a.d dua.-wa.elength Q-switched 1.5 μm fiber la.er using Ma. pha.e Cr2Tia.C2 sa.ura.le a.sorber

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Optoelectronics Letters 2025年第1期21卷 7-12页

作者： ahmed Sha.ir a.-HITI Hiba.Ha.Sa. Depa.tment of electrica. Engineering Faculty of Engineering University of Anbar Depa.tment of La.er a.d Optoelectronics Engineering University of Technology-Iraq

We demonstra.ed a.new type of Ma. pha.e ma.eria., chromium tita.ium a.uminum ca.bide（Cr2Tia.C2） polymer film, to genera.e a.pa.sively Q-switched erbium-doped fiber la.er（EDFL）. The film thickness wa. mea.ured to be a.ound 45 μm, which wa. fa.rica.ed using the embedding method with polyvinyl a.cohol（PVa. polymer a. hoster. The sa.ura.le a.sorber（Sa. film demonstra.es a.dua.-wa.elength pa.sively Q-switched EDFL which opera.es a. 1 531 nm a.d 1 560.19 nm, respectively. The Q-switching pulse dura.ion could be va.ied from 2.46 μs to 770 ns, while the repetition ra.e va.ied from 92.76 kHz to 106.6 kHz with a. increa.ing input pumping ra.ge from 154 mW to 300 mW. The ma.imum output power a.d pulse energy of 15.05 mW a.d 141.18 nJ were obta.ned a. the ma.imum input power of 300 mW, respectively.

关键词： Sa.ura.le a.sorbers

Va.cula. endothelia. growth fa.tor:a.double-edged sword in the development of white ma.ter lesions

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Neura. Regenera.ion Resea.ch 2025年第1期20卷 191-192页

作者： Na.ek Ma.ukja. Da.iel Fulton Zuba.r ahmed WMa.thijs Bla.kesteijn Séba.tien Foulquier Depa.tment of Pha.ma.ology a.d Toxicology Maastricht UniversityMaastrichtThe Netherlands Ca.IM-School for Ca.diova.cula. Disea.es Maastricht UniversityMaastrichtThe Netherlands Neuroscience a.d Ophtha.mology Institute of Inflammation and AgeingUniversity of BirminghamEdgbastonBirminghamUK Centre for Tra.ma.Sciences Resea.ch University of BirminghamEdgbastonBirminghamUK MHeNs-School for Menta. Hea.th a.d Neuroscience Maastricht UniversityMaastrichtThe Netherlands Depa.tment of Neurology Maastricht University Medical CenterMaastrichtThe Netherlands

a. the popula.ion a.es,the burden of a.e-rela.ed disea.es becomes ***,over 55 million people suffer from dementia.worldwide,with a.zheimer’s disea.e being the most common ***,it is becoming clea.er tha. underlying va.cula. pa.hology such a. cerebra. sma.l vessel disea.e(cSVD)ma. be a.more detrimenta. ca.se for dementia.Cua.ra.o-Godia.et a..,2018).It is estima.ed tha. 10%-30%of the elderly popula.ion a.d 35%-90%of a.l dementia.pa.ients exhibit signs of *** term cSVD refers to pa.hology a.fecting the sma.l vessels of the bra.n,which ca. lea. to la.una. cerebra. infa.cts,enla.ged periva.cula. spa.es,a.d cortica. hemorrha.es(Cua.ra.o-Godia.et a..,2018).CSVD is often a.socia.ed with cognitive decline,ga.t problems,a.d dementia.Cua.ra.o-Godia.et a..,2018).

关键词： pa.hology becoming white

LEO sa.ellite clock a.a.ysis a.d prediction for positioning a.plica.ions

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Geo-Spa.ia. Informa.ion Science 2022年第1期25卷 14-33页

作者： Ka. Wa.g ahmed el-Mowa.y School of Ea.th a.d Pla.eta.y Sciences Curtin UniversityPerthAustralia

The positioning service a.ded by low Ea.th orbit(LEO)mega.constella.ions ha. become a.hot topic in recent *** a.hieve precise positioning,a.cura.y of the LEO clocks is importa.t for single-receiver *** bridge the ga. between the a.plica.le time of the clock products a.d the time of positioning,the precise LEO clocks need to be predicted over a.certa.n period depending on the sa.pling interva. of the clock *** study discusses the prediction errors for periods from 10 s to 1 h for two typica. LEO clock types,*** ultra.sta.le oscilla.or(USO)a.d the oven-controlled crysta. oscilla.or(OCXO).The prediction is ba.ed on GNSS-determined precise clock estima.es,where the clock sta.ility is rela.ed to the GNSS estima.ion errors,the beha.iors of the oscilla.ors themselves,the systema.ic effects rela.ed to the environment a.d the rela.ivistic effects,a.d the sta.ility of the time *** on rea. da.a.a.a.ysis,LEO clocks of the two different types a.e simula.ed under different conditions,a.d a.prediction model considering the systema.ic effects is *** to a.simple polynomia. fitting model usua.ly a.plied,the proposed model ca. significa.tly reduce the prediction errors,*** a.out 40%-70%in simula.ions a.d a.out 5%-30%for rea. da.a.conta.ning different miss-modeled *** both clock types,short-term prediction of 1 min would result in a.root mea. squa.e error(RMSE)of a.few centimeters when using a.very sta.le time *** RMSE a.ounts to a.out 0.1 m,when a.typica. rea.-time time reference of the na.iona. center for spa.e studies(CNES)rea.-time clocks wa. *** long-term prediction of 1 h,the RMSE could ra.ge from below 1 m to a.few meters for the USOs,depending on the complexity of the miss-modeled *** OCXOs,the 1 h prediction could lea. to la.ger errors with a. RMSE of a.out 10 m.

关键词： LEO clock prediction USO OCXO rela.ivistic effects

Ma.netoresistive properties of Ni-doped La.(0.7)Sr_(0.3)MnO_3 ma.ga.ites

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Ra.e Meta.s 2016年第7期35卷 551-558页

作者： ahmed Moha.ed ahmed a.d el-Moez ahmed Moha.ed Medha. a.delra.y a.della.eef Ha.sa. ahmed a.d el-Gha.ny Physics Depa.tment Faculty of ScienceSohag University

La..7Sr0.3Mnl_xNixO3 （x = 0, 0.025, 0.050 a.d 0.075） cera.ics were prepa.ed by the conventiona. solid-sta.e rea.tion method. The pa.tia. substitution of Mn by Ni2＋ lea.s to a.decrea.e in cell volume a. well a. a.structura. tra.sition from the rhombohedra. to the orthorhombic structure. Ni2＋ doping increa.es the electrica. resistivity, decrea.es the semiconductor-meta. tra.sition tempera.ure （Tms） a.d rela.ively enha.ces the room tempera.ure ma.netoresista.ce （MR）, especia.ly in x = 0.025 a.d a.ound Tins. With respect to conduction mecha.ism, the sma.l pola.on hopping （SPH） a.d the va.ia.le ra.ge hopping （VRH） models were used to ex- a.ine conduction in the semiconducting region.

关键词： Ma.ga.ites X-ra. diffra.tion Structure electrica. resistivity Ma.netoresista.ce

Hepa.oprotective Effect of Ca.el Thorn Polyphenols in Conca.a.a.in a.Induced Hepa.itis in Mice

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Chinese Journa. of Integra.ive Medicine 2024年第12期30卷 1090-1100页

作者： Na.eh ahmed el-Ma.dy Tha.a. ahmed el-Ma.ry ahmed Ma.moud el-Ta.a.ony .Fa.ema. a.lherz Ena.s Youssef Osma. Depa.tment of Pha.ma.ology a.d Toxicology Faculty of PharmacyTanta UniversityTanta 31527Egypt Depa.tment of Pha.ma.eutica. Sciences College of PharmacyPrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia

Objective:To explore the prophyla.tic a.d thera.eutic effects of a.ha.i ma.rorum etha.olic extra.t(a.E)in conca.a.a.in a.Con a.-induced hepa.itis(CIH)a. well a. possible underlying ***:Polyphenols in a.E were cha.a.terized using high performa.ce liquid chroma.ogra.hy(HPLC).Swiss a.bino mice were divided into 4 *** group received intra.enous phospha.e-buffered sa.ine(PBS);Con a.group received 40 mg/kg intra.enous Con *** group a.ministered 300 mg/(kg·d)a.E ora.ly for 5 da.s before Con a.*** group received intra.enous Con a.then a.ministered300 mg/kg a.E a. 30 min a.d 3 h a.ter Con a.*** 24 h of Con a.injection,hepa.ic injury,oxida.ive stress,a.d infla.ma.ory media.ors were *** exa.ina.ion a.d ma.kers of a.optosis,infla.ma.ion,a.d CD4^(+)cell infiltra.ion were a.so ***:HPLC a.a.ysis revea.ed tha. a.E conta.ns a.unda.t polyphenols with pha.ma.ologica. constituents,such a. ella.ic a.id,ga.lic a.id,ferulic a.id,methylga.la.e,a.d *** a.levia.ed Con a.induced hepa.ic injury,a. ma.ifested by a.significa.t reduction in a.a.ine a.inotra.sfera.e,a.pa.ta.e a.inotra.sfera.e a.d a.ka.ine phospha.a.e(Pa.ditiona.ly,the a.tioxida.t effect of a.E wa. revea.ed by a.significa.t reduction in oxida.ive stress ma.kers(nitric oxide a.d ma.ondia.dehyde)a.d restored gluta.hione(Pels of proinfla.ma.ory cytokines(tumor necrosis fa.tor-α,interferon-γ,a.d interleukin-6)a.d c-Jun N-termina. kina.e(JNK)a.tivity were reduced(Pa.hologica. exa.ina.ion of liver tissue showed tha. a.E significa.tly a.eliora.ed necrotic a.d infla.ma.ory lesions induced by Con a.Pa.E reduced the expression of nuclea. fa.tor ka.pa.B,pro-a.optotic protein(Ba.),ca.pa.e-3,a.d CD4^(+)T cell hepa.ic infiltra.ion(Pa.ti-a.optotic protein Bcl-2 wa. increa.ed(Pa.E ha. hepa.oprotective a.d a.eliora.ive effects in CIH mice

关键词： conca.a.a.in a.induced hepa.itis a.ha.i ma.rorum etha.olic extra.t hepa.oprotective effect

Effect of CuO a.dition on the Sintering Beha.ior a.d electrica. Conductivity of 3Y-TZP

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Journa. of Ma.eria.s Science & Technology 2007年第1期23卷 131-134页

作者： ahmed a.Ha.sa. Oma. a.dela. a. S.M.el-Hout Dept. of Meta.lurgy Nuclear Research CenterAtomic Energy AuthorityCairoEgypt

Yttria.sta.ilized tetra.ona. zirconia.polycrysta.s （3Y-TZP） doped with CuO wa. prepa.ed, to get two compositions, 0.3 a.d 1 mole fra.tion CuO, respectively. The dila.ometric study of the sa.ples showed sintering to be improved for the sa.ples doped with 0.3 mole fra.tion CuO, a.d to be deteriora.ed for the sa.ples doped with 1 mole fra.tion CuO. The 1 mole fra.tion CuO doped 3Y-TZP showed higher tetra.ona./monoclinic pha.e tra.sforma.ion which wa. a.compa.ied by gra.n growth. The electrica. conductivity decrea.ed with the a.dition of CuO.

关键词： Y2O3 Sintering a.ds electrica. conductivity Fuel cells

Effica.y of octreotide in the prevention of complica.ions a.ter pa.crea.icoduodenectomy in pa.ients with soft pa.crea. a.d non-dila.ed pa.crea.ic duct: a.prospective ra.domized tria.

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Hepa.obilia.y & Pa.crea.ic Disea.es Interna.iona. 2018年第1期17卷 59-63页

作者： a.ma. el Na.eeb ahmed el Ga.a.by Ma.moud a.a.i ahmed Shehta.Hosa. Ha.ed Moha.ed el Refea.ahmed Moneer ahmed a.d el Ra.ee Ga.troenterology Surgica. Center Mansoura University

Ba.kground: The effica.y of octreotide to prevent postopera.ive pa.crea.ic fistula.POPF) of pa.crea.icoduodenectomy(PD) is still controversia.. This study a.med to eva.ua.e the effect of postopera.ive use of octreotide on the outcomes a.ter ***: This is a.prospective ra.domized controlled tria. for postopera.ive use of octreotide in pa.ients undergoing PD. Pa.ients with soft pa.crea. a.d pa.crea.ic duct a.domized to 2 *** I did not receive postopera.ive octreotide. Group II received postopera.ive octreotide. The prima.y end of the study is to compa.e the ra.e of ***: a.tota. of 104 pa.ients were included in the study a.d were divided into two ra.domized *** were no significa.t difference in overa.l complica.ions a.d its severity. POPF occurred in 11 pa.ients(21.2%) in group I a.d 10(19.2%) in group II, without sta.istica. significa.ce(P = 0.807). a.so, there wa. no significa.t differences between both groups rega.ding the incidence of bilia.y lea.a.e(P = 0.083), dela.ed ga.tric emptying(P = 0.472), a.d ea.ly postopera.ive morta.ity(P = 0.727).Conclusions: Octreotide did not reduce postopera.ive morbidities, reopera.ion a.d morta.ity ra.e. a.so, it did not a.fect the incidence of POPF a.d its clinica.ly releva.t va.ia.ts.

关键词： Pa.crea.icoduodenectomy Postopera.ive pa.crea.ic fistula Octreotide Peria.pulla.y tumor

Experimenta. a.d numerica. investiga.ion of the a.ra.ive wa.erjet ma.hining of a.uminum-7075-T6 for a.rospa.e a.plica.ions

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a.va.ces in Ma.ufa.turing 2021年第2期9卷 286-303页

作者： Joseck Nya.oro Ma.moud ahmed Ha.sa. el-Hofy Moha.ed el-Hofy Depa.tment of Industria. a.d Ma.ufa.turing Engineering Egypt-Japan University of Science and Technology(E-JUST)Alexandria 21934Egypt Depa.tment of Energy Resources Engineering Egypt-Japan University of Science and Technology(E-JUST)Alexandria 21934Egypt a.va.ced Ma.ufa.turing Resea.ch Centre(a.RC)with Boeing The University of SheffieldRotherham S605TZUK

The ma.hining of ha.d-to-cut ma.eria.s with a.high degree of precision a.d high surfa.e qua.ity is one of the most critica. considera.ions when fa.rica.ing va.ious sta.e-of-the-a.t engineered *** this investiga.ion,a.comprehensive three-dimensiona. model wa. developed a.d numerica.ly simula.ed to predict kerf profiles a.d ma.eria. remova. ra.es while drilling the a.uminum-7075-T6 a.rospa.e *** profile a.d ma.eria. remova. prediction involved three sta.es:jet dyna.ic flow modeling,a.ra.ive pa.ticle tra.king,a.d erosion ra.e *** investiga.ions were conducted to va.ida.e the developed *** results indica.e tha. the jet dyna.ic cha.a.teristics a.d flow of a.ra.ive pa.ticles a.ter the kerf profiles,where the top kerf dia.eter increa.es with increa.ing jet pressure a.d sta.doff *** kerf depth a.d hole a.pect ra.io increa.e with jet pressure,but decrea.e with sta.doff dista.ce a.d ma.hining *** profiles were cha.a.terized by progressive edge rounding a.d pa.a.olic *** ca. be minimized by utilizing high jet pressure a.d sma.l sta.doff *** ma.eria. remova. ra.e increa.es with increa.ing jet pressure,a.ra.ive pa.ticle size,a.d exposure time,but decrea.es with increa.ing sta.doff dista.ce.

关键词： Non-tra.itiona. ma.hining a.ra.ive wa.erjet ma.hining Computa.iona. fluid dyna.ics(CFD) Erosion modeling Kerf cha.a.teristics