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Genes & Diseases 2023年第1期10卷 239-253页

作者： Kun Zhang Xian Qin Juhui Qiu Tong Sun Kai Qu ahmad ud din Wenhua Yan Tianhan Li Yidan Chen Wei Gu Xiancai Rao Guixue Wang Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular ImplantsCollege of BioengineeringChongqing UniversityChongqing 400044China College of Information and Management Sciences Henan Agricultural UniversityZhengzhouHenan 450046China School of Medicine Chongqing UniversityChongqing 400030China Department of Microbiology College of Basic Medical SciencesArmy Medical University(Third Military Medical University)Chongqing 400037China

It is increasingly aware that gut microbiota is closely associated with ***,which and how specific gut bacteria regulate the progression of atherosclerosis is still poorly *** this study,modified linear discriminant analysis was performed in comparing the gut microbiota structures of atherosclerotic and non-atherosclerotic mice,and Desulfovibrio desulfuricans(***)was found to be associatedwith ***-treated Apoe^(-/-) mice showed significantly aggravated *** proatherogenic effect of *** was attributed to its ability to increase intestinal permeability and subsequent raise in the transit of lipopolysaccharide(LPS)from the intestine to the *** LPS in the blood can elicit local and systemic inflammation and activate Toll-like receptor 4(TLR4)/nuclear factor-kB(NF-kB)signaling of endothelial ***-242,a specific inhibitor of TLR4,can ameliorate the development of *** atherosclerosis by blocking the LPS-induced activation of TLR4/NF-kB signaling.

关键词： Atherosclerosis Desulf ovibrio desulfuricans Gut microbiota Linear discriminant analysis TAK-242

Enhanced biological nutrient removal by the alliance of a heterotrophic nitrifying strain with a nitrogen removing ecosystem

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Journal of Environmental Sciences 2008年第2期20卷 216-223页

作者： Naeem ud din ahmad XU Haiying CHEN Liping LIU Zhipei LIU Shuangjiang State Key Laboratory of Microbial Resources Institute of Microbiology Chinese Academy of Sciences Beijing 100080 China Graduate School of Chinese Academy of Sciences Beijing 100049 China

Nitrogen removal from synthetic wastewater was investigated in an airlift bioreactor （ALB）, augmented with a novel heterotrophic nitrifier Pseudonocardia ammonioxydans H9^T under organic carbon to nitrogen ratios （Corg/N） ranging from 0 to 12. Effect of the inoculated strain was also determined on the settling properties and the removal of chemical oxygen demand （COD）. Two laboratory scale reactors were set up to achieve a stable nitrifying state under the same physicochemical conditions of hydraulic retention time （HRT）, temperature, pH and dissolved oxygen （DO）, and operated under the sequencing batch mode. The level of DO was kept at 0.5- 1.5 mg/L by periodic stirring and aeration. Each specific Corg/N ratio was continued for duration of 3 weeks. One of the reactors （BR2） was inoculated with P ammonioxydans H9^T periodically at the start of each Corg/N ratio. Sludge volumetric index （SVI） improved with the increasing Corg/N ratio, but no significant difference was detected between the two reactors. BR2 showed higher levels of nitrogen removal with the increasing heterotrophic conditions, and the ammonia removal reached to the level of 82%-88%, up to10% higher than that in the control reactor （BR1） at Corg/N ratios higher than 6; however, the ammonia removal level in experimental reactor was up to 8% lower than that in control reactor at Corg/N ratios lower than 2. The COD removal efficiency progressively increased with the increasing Corg/N ratios in both of the reactors. The COD removal percentage up to peak values of 88%-94% in BR2, up to 11% higher than that in BR1 at Corg/N ratio higher than 4. The peak values of ammonia and COD removal almost coincided with the highest number （18%-27% to total bacterial number） of the exogenous bacterium in the BR2, detected as colony forming units （CFU）. Furthermore, the removal of ammonia and COD in BR2 was closely related to the number of the inoculated strain with a coefficient index （R2） up to 0.82 and 0.85 for ammonia

关键词： air-lift bioreactor (ALB) bioaugrnentation Corg/N ratio COD and ammonia removal sequencing batch mode heterotrophic nitrifier Pseudonocardia ammonioxydans H9^T

Stability analysis of a fractional-order cancer model with chaotic dynamics

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International Journal of Biomathematics 2021年第6期14卷 239-261页

作者： Parvaiz ahmad Naik Jian Zu Mehraj-ud-din Naikt School of Mathematics and Statistics Xi’an Jiaotong University Xi’anShaanxi 710049P.R.China Department of Chemical Engineering College of Engineering Jazan UniversityJazan 45142Saudi Arabia

In this paper,we develop a three-dimensional fractional-order cancer *** proposed model involves the interaction among tumor cells,healthy tissue cells and activated effector *** detailed analysis of the equilibrium points is ***,the existence and uniqueness of the solution are *** fractional derivative is considered in the Caputo *** simulations are performed to illustrate the effectiveness of the obtained theoretical *** outcome of the study reveals that the order of the fractional derivative has a significant effect on the dynamic ***,the calculated Lyapunov exponents give the existence of chaotic behavior of the proposed ***,it is observed from the obtained results that decrease in fractional-order p increases the chaotic behavior of the model.

关键词： Cancer model Caputo fractional derivative chaos stability analysis.

IoT Devices Authentication Using Artificial Neural Network

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Computers, Materials & Continua 2022年第2期70卷 3701-3716页

作者： Syed Shabih Ul Hasan Anwar Ghani Ikram ud din ahmad Almogren Ayman Altameem Department of Computer Science and Software Engineering International Islamic University Islamabad45000Pakistan Department of Information Technology The University of Haripur22620HaripurPakistan Chair of Cyber Security Department of Computer ScienceCollege of Computer and Information SciencesKing Saud UniversityRiyadh11633Saudi Arabia Chair of Cyber Security Department of Natural and Engineering SciencesCollege of Applied Studies and Community ServicesKing Saud UniversityRiyadh11543Saudi Arabia

User authentication is one of the critical concerns of information *** tend to use strong textual passwords,but remembering complex passwords is hard as they often write it on a piece of paper or save it in their mobile *** passwords are slightly unprotected and are easily *** attacks include dictionary,shoulder surfing,and brute *** passwords overcome the shortcomings of textual passwords and are designed to aid memorability and ease of *** paper proposes a Process-based Pattern Authentication(PPA)system for Internet of Things(IoT)devices that does not require a server to maintain a static password of the login *** server stores user’s information,which they provide at the time of registration,i.e.,the R-code and the symbol,but the P-code,i.e.,the actual password,will change with every login attempt of *** this scheme,users may draw a pattern on the basis of calculation from the P-code and Rcode in the PPA pattern,and can authenticate themselves using their touch dynamic behaviors through Artificial Neural Network(ANN).The ANN is trained on touch behaviors of legitimate users reporting superior performance over the existing *** experimental purposes,PPA is implemented as a prototype on a computer system to carry out experiments for the evaluation in terms of memorability and *** experiments show that the system has an effect of 5.03%of the False Rejection Rate(FRR)and 4.36%of the False Acceptance Rate(FAR),respectively.

关键词： Implicit authentication behavioral authentication artificial neural network processed pattern authentication

Response of Wheat to Tillage Plus Rice Residue and Nitrogen Management in Rice-Wheat System

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Journal of Integrative Agriculture 2014年第11期13卷 2389-2398页

作者： Khalid Usman Ejaz ahmad Khan Niamatullah Khan Abdur Rashid Fazal Yazdan Saleem ud din Department of Agronomy Faculty of Agriculture Gomal UniversityD. I. Khan 29050 Pakistan Cotton Research Station Ratta KulachiD. I. Khan 29050 Pakistan Arid Zone Research Institute Ratta KulachiD. I. Khan 29050 Pakistan Oil Seed Research Program National Agricultural Research CentreIslamabad 44000Pakistan

Zero tillage with residues retention and optimizing nitrogen fertilization are important strategies to improve soil quality and wheat （Triticum aestivum L.） yield in rice （Oryza sativa L.）-wheat system. Field experiments were conducted on silty clay soil （Hyperthermic, and Typic Torrilfuvents） in D. I. Khan, Pakistan, to explore the impact of six tillage methods （zero tillage straw retained （ZTsr）, ZT straw burnt （ZTsb）, reduced tillage straw incorporated （RTsi, including tiller and rotavator）, RT straw burnt （RTsb）, conventional tillage straw incorporated （CTsi, including disc plow, tiller, rotavator, and leveling operations）, CT straw burnt （CTsb）） and ifve nitrogen rates, i.e., 0, 100, 150, 200, and 250 kg ha-1 on wheat yield. Mean values for N revealed that spikes m-2, grains/spike, 1 000-grain weight （g）, and grain yield （kg ha-1） were signiifcantly higher at 200 kg N ha-1 in both the years as well as mean over years than all other treatments. Mean values for tillage revealed that ZTsr produced highest number of spikes m-2 among tillage methods. However, grains/spike, 1 000-grain weight, and grain yield were higher in tillage methods with either straw retained/incorporated than tillage methods with straw burnt. Interaction effects were signiifcant in year 1 and in mean over years regarding spikes m-2, 1 000-grain weight, total soil organic matter （SOM）, and total soil N （TSN）. ZTsr produced the most spikes m-2 and 1 000-grain weight at 200 kg N ha-1. ZTsr also produced higher SOM and TSN at 200-250 kg N ha-1 at the end of 2 yr cropping. Thus ZTsr with 200 kg N ha-1 may be an optimum and sustainable approach to enhance wheat yield and soil quality in rice-wheat system.

关键词： wheat yield tillage nitrogen TSN SOM

Short Response of Spring Wheat to Tillage, Residue Management and Split Nitrogen Application in a Rice-Wheat System

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Journal of Integrative Agriculture 2014年第12期13卷 2625-2633页

作者： Khalid Usman Ejaz ahmad Khan Fazal Yazdan Niamatullah Khan Abdur Rashid Saleem ud din Department of Agronomy Faculty of Agriculture Gomal UniversityD. I. Khan 29050 Pakistan Oil Seed Research Programme National Agricultural Research Center (NARC) Cotton Research Station Ratta Kulachi D. I. Khan 29050 Pakistan Arid Zone Research Institute Ratta Kulachi D. I. Khan 29050 Pakistan

A ifeld experiment was conducted to study the impact of tillage, crop residue management and nitrogen （N） splitting on spring wheat （Triticum aestivum L.） yield over 2 yr （2010-2012） in a rice （Oryza sativa L.）-wheat system in northwestern Pakistan. The experiment was conducted as split plot arranged in randomized complete blocks design with three replications. Treatments comprised six tillage and residue managements：zero tillage straw retained （ZTsr）, zero tillage straw burnt （ZTsb）, reduced tillage straw incorporated （RTsi）, reduced tillage straw burnt （RTsb）, conventional tillage straw incorporated （CTsi）, and conventional tillage straw burnt （CTsb） as main plots and N （200 kg ha-1） was applied as split form viz., control （no nitrogen＆no splitting, N0S0）;2 splits of total N, half at sowing and half at the 1st irrigation （i.e., 20 d after sowing （DAS））（NS1）;3 splits of total N, 1/3 at sowing, 1/3 at the 1st irrigation, and 1/3 at the 2nd irrigation （NS2）;4 splits of total N, 1/4 at sowing, 1/4 at the 1st irrigation, 1/4 at the 2nd irrigation （45 DAS）, and 1/4 at the 3rd irrigation （70 DAS）（NS3）;and 4 splits of total N, 1/4 at the 1st irrigation, 1/4 at the 2nd irrigation, 1/4 at the 3rd irrigation, and 1/4 at the 4th irrigation （95DAS）（NS4） as sub plots. The results showed that the most pikes m-2, grains/spike, 1 000-grain weight, grain yield, and N use efifciency （NUE） were obtained at zero tillage, straw retained and 4 splits application of total N （i.e., at sowing 20, 45 and 70 d after sowing）. The results indicated that ZTsr with application of 200 kg N ha-1 in 4 equal splits viz. at sowing 20, 45 and 70 d after sowing is an appropriate strategy that enhanced wheat yield （7 436-7 634 kg ha-1） and N efifciency （28.6-29.5 kg kg-1） in rice-wheat system.

关键词： tillage residue management N split application wheat yield

AI-Driven Pattern Recognition in Medicinal Plants: A Comprehensive Review and Comparative Analysis

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Computers, Materials & Continua 2024年第11期81卷 2077-2131页

作者： Mohd Asif Hajam Tasleem Arif Akib Mohi ud din Khanday Mudasir ahmad Wani Muhammad Asim Department of Information Technology Baba Ghulam Shah Badshah UniversityRajouriJammu and Kashmir185234India Department of Computer Science Samarkand International University of TechnologySamarkand141500Uzbekistan EIAS Data Science Lab College of Computer and Information SciencesPrince Sultan UniversityRiyadh11586Saudi Arabia

The pharmaceutical industry increasingly values medicinal plants due to their perceived safety and costeffectiveness compared to modern *** the extensive history of medicinal plant usage,various plant parts,including flowers,leaves,and roots,have been acknowledged for their healing properties and employed in plant *** images,however,stand out as the preferred and easily accessible source of *** plant identification by plant taxonomists is intricate,time-consuming,and prone to errors,relying heavily on human *** intelligence(AI)techniques offer a solution by automating plant recognition *** study thoroughly examines cutting-edge AI approaches for leaf image-based plant identification,drawing insights from literature across renowned *** paper critically summarizes relevant literature based on AI algorithms,extracted features,and results ***,it analyzes extensively used datasets in automated plant classification *** also offers deep insights into implemented techniques and methods employed for medicinal plant ***,this rigorous review study discusses opportunities and challenges in employing these AI-based ***,in-depth statistical findings and lessons learned from this survey are highlighted with novel research areas with the aim of offering insights to the readers and motivating new research *** review is expected to serve as a foundational resource for future researchers in the field of AI-based identification of medicinal plants.

关键词： Pattern recognition artificial intelligence machine learning deep learning image processing plant leaf identification

Advances and challenges of methanol-tolerant oxygen reduction reaction electrocatalysts for the direct methanol fuel cell

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Journal of Energy Chemistry 2023年第2期77卷 499-513,I0013页

作者： Muhammad Aizaz ud din Muhammad Idrees Sidra Jamil Syed Irfan Ghazanfar Nazir Muhammad ahmad Mudassir Muhammad Shahrukh Saleem Saima Batool Nanpu Cheng Rahman Saidur School of Materials and Energy Southwest UniversityChongqing 400715China Additive Manufacturing Institute College of Mechatronics and Control EngineeringShenzhen UniversityShenzhen 518060GuangdongChina Chongqing Key Lab for Advanced Materials and Clean Energies of Technologies School of Materials and EnergySouthwest UniversityChongqing 400715China School of Materials Science and Engineering Dongguan University of TechnologyDongguan 523808GuangdongChina Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea Department of Chemistry Khawaja Fareed University of Engineering and Information TechnologyRahim Yar Khan 64200Pakistan Laboratory for High Performance Ceramics EmpaSwiss Federal Laboratories for Materials Science and Technology8600 DübendorfSwitzerland Institute for Advanced Study Shenzhen UniversityShenzhen 518060GuangdongChina Research Centre for Nano-Materials and Energy Technology School of Engineering and TechnologySunway UniversityBandar SunwayMalaysia Department of Engineering Lancaster UniversityLancasterUnited Kingdom

Methanol cross-over effects from the anode to the cathode are important parameters for reducing catalytic performance in direct methanol fuel cells.A promising candidate catalyst for the cathode in direct methanol fuel cells must have excellent activity toward oxygen reduction reaction and resistance to methanol oxidation *** review focuses on the methanol tolerant noble metal-based electrocatalysts,including platinum and palladium-based alloys,noble metal–carbon based composites,transition metal-based catalysts,carbon-based metal catalysts,and metal-free *** understanding of the correlation between the activity and the synthesis method,electrolyte environment and stability issues are *** the transition metal-based catalyst,their activity,stability and methanol tolerance in direct methanol fuel cells and comparisons with those of platinum are particularly ***,strategies to enhance the methanol tolerance and hinder the generation of mixed potential in direct methanol fuel cells are also *** review provides a perspective for future developments for the scientist in selecting suitable methanol tolerate catalyst for oxygen reduction reaction and designing high-performance practical direct methanol fuel cells.

关键词： Oxygen reducing reaction Methanol tolerant electrocatalyst Portable power sources Direct methanol Fuel cell

Pattern of hepatitis C virus genotypes and subtypes circulating in war-stricken Khyber Pakhtunkhwa,Pakistan:Review of published literature

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Asian Pacific Journal of Tropical Medicine 2017年第11期10卷 1037-1042页

作者： Abdul Waheed Khan Sadia Nawab Zeeshan Nasim Abdul Haleem Khan Syed Ishfaq ahmad Fazli Zahir Israr ud din Institute of Information Sciences Academia SinicaTaiwan Center for Biotechnology and Microbiology University of SwatPakistan Institute of Biotechnology and Genetic Engineering The University of AgriculturePeshawarPakistan 4Department of ZoologyIslamia College PeshawarPakistan

Infection due to hepatitis C virus(HCV) is a major cause of fibrosis and hepatocellular carcinoma in Pakistan. In the current review, pattern of HCV genotypes and subtypes in Khyber Pakhtunkhwa province was ascertained in light of the available literature. After thorough analysis, genotype 3(58.27%) was determined to be the leading HCV genotype,followed by genotypes 2(12.39%), 1(9.54%) and 4(0.86%). The proportions of genotypes 5 and 6 were recorded as 0.09% and 0.22% respectively. Subtype wise, 3 a accounted for 48.67%, followed by subtype 2 a(10.91%), 3 b(9.43%), 1 a(5.84%), 1 b(3.66%), 2 b(1.45%) and genotype 4 with its undefined subtypes contributed a portion of0.86%. The cumulative share of subtypes 1 c, 2 c, 3 c, 5 a and 6 a was less than 1%. In11.51% cases, the subtype was untypeable while in 7.17% cases mixed subtypes were recorded. Gender wise, proportions of most HCV subtypes were marginally higher among males as compared to females. On the basis of studied groups, 3 a was pervasive among all groups except in intravenous drug users where 2 a was the major HCV ***, based on various geographical locations(provincial divisions), subtype 3 a revealed a ubiquitous distribution. Conclusively, HCV 3 a persists to be the principal subtype across the province of Khyber Pakhtunkhwa. The considerable number of untypeable subtypes in most studies urges for an improved genotyping system on the basis of local sequence data and practice of sequencing for determination of underlying subtype in untypeable cases. Further, studies on identification of subtypes transmission pattern are imperative for assessment of transmission origin and reinforcement of efficient control strategies. In addition, the current review emphasizes the need of attention toward HCV risk groups and ignored southern side of Khyber Pakhtunkhwa province for better holistic understanding of HCV genotype distribution pattern in the province.

关键词： Hepatitis C Hepatitis C virus Genotype Subtype

Synthesis of zinc oxide nanoparticles reinforced clay and their applications for removal of Pb(II)ions from aqueous media

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Chinese Journal of Chemical Engineering 2021年第4期34卷 454-461页

作者： Abdul Samad Muhammad Imran din Mahmood Ahmed Saghir ahmad Institute of Chemistry University of the PunjabLahore 54590Pakistan Renacon Pharma Limited Lahore 54600Pakistan

The aim of the study was to synthesize zinc oxide nanoparticles(ZnONPs)composite with clay by a novel route and then to explore the capability of composite of ZnONPs and silty clay(SC)as adsorbents for Pb(II)eradication from aqueous media by batch adsorption *** effect of different operating factors like temperature,pH,dose and time of contact on the adsorption process were studied to optimize the ***,Freundlich,Dubinin-Radushkevich(DR)and Temkin isotherms were applied for the interpretation of the *** R^(2)and q values obtained from Langmuir model suggested that the process is best interpreted by this *** values of adsorption capacity(qm)noted were 12.43 mg·g^(-1) and 14.54 mg·g^(-1)on SC and ZnONPsSC *** kinetic studies exposed that pseudo second order(PSO)kinetics is followed by the processes suggesting that more than one steps are involved to control the rate of *** thermodynamic variables such as change in free energy(AGe),change in enthalpy(AH9)and change in entropy(ASe)were *** data suggested that Pb(II)adsorption on SC and ZnONPsSC are spontaneous,endothermic and feasible processes.

关键词： Adsorption Isotherm Kinetics Silty clay Thermodynamic