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Biofabrication of natural hydrogels for cardiac,neural,and bone Tissue engineering Applications

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Bioactive Materials 2021年第11期6卷 3904-3923页

作者： kamil Elkhoury Margaretha Morsink Laura Sanchez-Gonzalez Cyril Kahn Ali Tamayol Elmira Arab-Tehrany LIBio Universite de LorraineNancyF-54000France Department of Applied Stem Cell Technologies TechMed CentreUniversity of TwenteEnschede7500AEthe Netherlands Department of Biomedical Engineering University of ConnecticutFarmingtonCT06030USA

Natural hydrogels are one of the most promising biomaterials for tissue engineering applications,due to their biocompatibility,biodegradability,and extracellular matrix mimicking *** surpass the limitations of conventional fabrication techniques and to recapitulate the complex architecture of native tissue structure,natural hydrogels are being constructed using novel biofabrication strategies,such as textile techniques and three-dimensional *** innovative techniques play an enormous role in the development of advanced scaffolds for various tissue engineering *** progress,advantages,and shortcomings of the emerging biofabrication techniques are highlighted in this ***,the novel applications of biofabricated natural hydrogels in cardiac,neural,and bone tissue engineering are discussed as well.

关键词： Hydrogel Microfabrication Bioprinting Textiles Tissue engineering Regenerative medicine

Development of anti-corrosive coating on AZ31 Mg alloy subjected to plasma electrolytic oxidation at sub-zero temperature

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Journal of Magnesium and Alloys 2022年第7期10卷 1915-1929页

作者： S.Fatimah M.P.kamil D.I.Han W.Al-Zoubi Y.G.Ko Materials Electrochemistry Group School of Materials Science and EngineeringYeungnam UniversityGyeongsan 38541Republic of Korea

Plasma electrolytic oxidation(PEO)is a promising surface treatment to generate adherent and thick anti-corrosive coating on light-weight metals(Al,Mg,Ti,etc.)using an eco-friendly alkaline *** energy plasma,however,inevitably generates porous structures that limit their practical *** present study proposes a straight-forward simple method by utilizing sub-zero electrolyte(268 K)to alter the plasma characteristics during formation of the protective coating on AZ31 Mg alloy via PEO with a comparison to the electrolyte at room temperature(298 K).In refrigerated electrolyte,the formation of micro-defects is suppressed relatively at the expense of low coating growth,which is measured to be twice lower than that at 298 K due to the temperature-dependent soft plasma discharges contributing to the development of the present *** a consequence,corrosion resistance of the sample processed at 268 K is superior to that of 298K,implying that the effect of coating thickness is less dominant than that of *** phenomenon is interpreted in relation to the ionic movement and oxide solidification controlled by soft plasma discharges arising from the temperature gradient between electrolyte and surface of the substrate during PEO.

关键词： AZ31 Mg alloy Plasma electrolytic oxidation Sub-zero electrolyte Anti-corrosive coating Corrosion

Toxic Currency Options in Poland as a Consequence of the 2008 Financial Crisis

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Chinese Business Review 2015年第12期14卷 561-572页

作者： kamil Liberadzki Warsaw School of Economics Warszawa Poland

The paper is on toxic foreign exchange options problem which occurred in Poland just prior to and after the outbreak of the recent crisis. Especially Polish enterprises were severely stricken by transactions on fx and interest rate derivatives contracted with their banks. Poland was the only EU country which did not precipitate into recession during the financial crisis beginning in 2008. However, the toxic fx and interest rate derivatives transmitted the shockwaves from global financial markets into Poland. Huge dimensions of losses resulted in conflicts between banks and their customers, who claimed just being cheated by the financial institutions. The article deeply researches into reasons for such developments on Polish fx over-the-counter derivatives market. As a case study, an authentic strategy has been presented. The contract was concluded between the construction company and one of the biggest commercial banks in Poland. Because the case study may be representative for many other cases, the analysis includes exact pricing of option strategy and therefore reveals inequality of the contract. The consequences of non-implementing the MiFID directive in the context of derivatives offering to non-financial customers were also touched in the paper.

关键词： toxic foreign exchange options MiFID risk reversal foreign exchange portfolio hedging exotic options barrier options option strategies

3D surface profile diagnosis using digital image processing for laboratory use

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Journal of Central South University 2020年第3期27卷 811-823页

作者： Robert FRISCHER Ondrej KREJCAR Ali SELAMAT kamil KUCA Center for Basic and Applied Research Faculty of Informatics and ManagementUniversity of Hradec KraloveRokitanskeho 62Hradec Kralove 50003Czech Republic Malaysia Japan International Institute of Technology(MJIIT) Universiti Teknologi Malaysia Kuala LumpurJalan Sultan Yahya PetraKuala Lumpur 54100Malaysia Media and Games Center of Excellence(MagicX) Universiti Teknologi MalaysiaSkudai 81310Malaysia School of Computing Faculty of EngineeringUniversiti Teknologi Malaysia(UTM)Skudai 81310Malaysia

The measurement of the surface quality and the profile preciseness is major issues in many industrial branches such that the surface quality of semi products directly affects the subsequent production ***,there are many ways to obtain required data,the hardware necessary for the measurements such as 2D or 3D scanners,depending on the problem’s complexity,is too ***,in this paper,what we put forward as a novelty is an algorithm which is verified on the model of simple 3D scanner on the image processing basis with the resolution of 0.1 *** are many ways to scan surface profile;however,the image processing currently is the most trending topic in industry *** importantly,in order to obtain surface images,standard high resolution reflex camera is used and thus the post processing could be realized with MatLab as the software ***,this solution is an alternative to the expensive scanners,and single-purpose devices could be extended by many additional functions.

关键词： profile diagnostics image processing 3D surface MatLab measurement

Low symptomatic COVID-19 in an elderly patient with follicular lymphoma treated with rituximab-based immunotherapy:A case report

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World Journal of Clinical Cases 2021年第18期9卷 4859-4865页

作者： StanisławŁącki Kinga Wyżgolik MichałNicze Sylwia Georgiew-Nadziakiewicz Jerzy Chudek kamil Wdowiak Department of Internal Diseases and Oncological Chemotherapy Medical University of SilesiaKatowice 40-027Silesian VoivodeshipPoland Imaging and Isotope Diagnostics Department Chorzów General HospitalChorzów 41-500Silesian VoivodeshipPoland

BACKGROUND Follicular lymphoma is an indolent lymphoma that may progress to a highly aggressive form requiring *** regimens utilize rituximab,an anti-CD20 monoclonal antibody,which may affect the clinical course of novel coronavirus,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infections[coronavirus disease 2019(COVID-19)].Here we describe the first case of mild COVID-19 during ongoing oncological treatment without significant deterioration after rituximab *** SUMMARY A 74-year-old female with an enlargement of her right palatine tonsil was diagnosed with follicular lymphoma following tonsillectomy and started immunochemotherapy according to the rituximab,cyclophosphamide,vincristine,prednisone *** home before the fourth cycle,she developed nonspecific symptoms(excessive fatigue,loss of appetite and nausea),misdiagnosed as adverse effects of ***,interim positron emission tomography-computed tomography scan,performed shortly before rituximab administration,revealed previously nonexistent pulmonary changes,potentially of infectious ***-CoV-2 infection was confirmed by a nasopharyngeal swab(with reverse transcriptase polymerase chain reaction test)performed the following *** rituximab infusion,the patient remained oligosymptomatic and was discharged home for *** reached a negative SARS-CoV-2 status before the subsequently scheduled regimen,the patient successfully received six cycles of rituximab,cyclophosphamide,vincristine,prednisone and obtained complete remission by positron emission tomographycomputed *** Our case shows that rituximab-based immunotherapy due to follicular lymphoma may have no evident negative effect on the COVID-19 clinical course.

关键词： COVID-19 SARS-CoV-2 Follicular lymphoma Rituximab Case report

Automated decision support for Hallux Valgus treatment options using anteroposterior foot radiographs

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World Journal of Orthopedics 2023年第11期14卷 800-812页

作者： Konrad Kwolek Artur Gądek kamil Kwolek Radek Kolecki Henryk Liszka Department of Orthopedics and Traumatology University HospitalKraków 30-688MałopolskaPoland Department of Orthopedics and Physiotherapy Jagiellonian University Collegium MedicumKraków 30-688MałopolskaPoland Department of Spine Disorders and Orthopedics Gruca Orthopedic and Trauma Teaching HospitalOtwock 05-400Poland

BACKGROUND Assessment of the potential utility of deep learning with subsequent image analysis to automate the measurement of hallux valgus and intermetatarsal angles from radiographs to serve as a preoperative aid in establishing hallux valgus severity for clinical *** To investigate the accuracy of automated measurements of angles of hallux valgus from radiographs for further integration with the preoperative planning *** The data comprises 265 consecutive digital anteroposterior weightbearing foot radiographs.181 radiographs were utilized for training(161)and validating(20)a U-Net neural network to achieve a mean Sørensen–Dice index>97%on bone segmentation.84 test radiographs were used for manual(computer assisted)and automated measurements of hallux valgus severity determined by hallux valgus(HVA)and intermetatarsal angles(IMA).The reliability of manual and computerbased measurements was calculated using the interclass correlation coefficient(ICC)and standard error of measurement(SEM).Inter-and intraobserver reliability coefficients were also *** operative treatment recommendation was then applied to compare results between automated and manual angle *** Very high reliability was achieved for HVA and IMA between the manual measurements of three independent *** HVA,the ICC between manual measurements was *** IMA,ICC was *** manual against automated computer measurement,the reliability was high as *** HVA,absolute agreement ICC and consistency ICC were 0.97,and SEM was *** IMA,absolute agreement ICC was 0.75,consistency ICC was 0.89,and SEM was ***,a strong correlation(0.80)was observed between our approach and traditional clinical adjudication for preoperative planning of hallux valgus,according to an operative treatment algorithm proposed by *** The proposed automated,artificial intelligence assisted determination of hallux valgus angles

关键词： Computer-aided diagnosis Artificial intelligence in orthopedics Automated preoperative decision support Deep learning Medical imaging

Exploring a natural MDR reversal agent: potential of medicinal food supplement Nerium oleander leaf distillate

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Asian Pacific Journal of Tropical Biomedicine 2013年第8期3卷 644-649页

作者： Meltem Demirel Kars Ufuk Gündüz kamilüney AhmetLevent Ba Seluk University Saraynü Vocational High School42430 KonyaTurkey Seluk University Advanced Technology Research and Application Center42075 KonyaTurkey Middle East Technical University Department of Biological Sciences06531 AnkaraTurkey Selcuk University Faculty of Veterinary MedicineDepartment of Toxicology and Pharmacology42075KonyaTurkey Selcuk University Faculty of Veterinary MedicineDepartment of Toxicology and Pharmacology42075KonyaTurkeyy

Objective:To investigate the molecular effects ofNerium oleanderleaf distillate on paclitaxel and vincristine resistant(MCF-7/Pac and MCF-7/Vinc)cells and sensitive(MCF-7/S)cell ***:Nerium oleander(***)leaf extract was obtained by hydrodistillation *** toxicological effects ***,previously suggested as medicinal food supplement,on drug resistant cells were evaluated by XTT *** modulation potential of the plant material was evaluated by flow cytometry and fluorescent *** and vincristine were applied to the sublines in combination with ***:Fractional inhibitory indices show *** did not increase the antiproliferative effects of anticancer *** in to MCF-7/Pac and MCF-7/Vinc did not inhibit P-gp activity and MDR1 gene expression ***:As a result it may be suggested that *** has some medicinal effects as food supplement it may not be suitable as an MDR modulator for drug resistant breast cancer cells.

关键词： Nerium oleander MCF-7 FRSA activity MDR reversal Medicinal food supplement

Effects of the nitrification inhibitor nitrapyrin and the plant growth regulator gibberellic acid on yield-scale nitrous oxide emission in maize fields under hot climatic conditions

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Pedosphere 2021年第2期31卷 323-331页

作者： Khadim DAWAR kamil SARDAR Mohammad ZAMAN Christoph MÜLLER Alberto SANZ-COBENA Aamir KHAN Azam BORZOUEI Ana Gabriela PÉREZ-CASTILLO Department of Soil and Environmental Science University of Agriculture PeshawarPeshawa 25000(Pakistan) Soil and Water Management&Crop Nutrition Joint FAO/IAEA Division of Nuclear Techniques in Food&AgricultureP.O.Box 100Vienna A-1400(Austria) Institute of Plant Ecology Justus Liebig UniversityHeinrich-Buff-Ring 26Giessen D-35392(Germany) School of Biology and Environmental Science University College DublinBelfieldD04 V1W8(Ireland) Management of Environment and Agricultural Risks(CEIGRAM) ETSIAABUniversidad Poliécnica de MadridMadrid 28040(Spain) Agricultural Research School Nuclear Science and Technology Research InstituteP.O.Box 31465/1498Karaj(Iran) Environmental Pollution Research Center(CICA) University of Costa RicaMontes de Oca 11501(Costa Rica)

Nitrification inhibitors are widely used in agriculture to mitigate nitrous oxide(N_(2)O)emission and increase crop ***,no concrete information on their mitigation of N_(2)O emission is available under soil and environmental conditions as in Pakistan.A field experiment was established using a silt clay loam soil from Peshawar,Pakistan,to study the effect of urea applied in combination with a nitrification inhibitor,nitrapyrin(2-chloro-6-tri-chloromethyl pyridine),and/or a plant growth regulator,gibberellic acid(GA_3),on N_(2)O emission and the nitrogen(N)uptake efficiency of *** experimental design was a randomized complete block with five treatments in four replicates:control with no N(CK),urea(200 kg N ha^(-1))alone,urea in combination with nitrapyrin(700 g ha^(-1)),urea in combination with GA_3(60 g ha^(-1)),and urea in combination with nitrapyrin and GA_*** N_(2)O emission,yield,N response efficiency,and total N uptake were measured during the experimental *** treatment with urea and nitrapyrin reduced total N_(2)O emission by 39%–43%and decreased yield-scaled N_(2)O emission by 47%–52%,relative to the treatment with urea *** maize plant biomass,grain yield,and total N uptake increased significantly by 23%,17%,and 15%,respectively,in the treatment with urea and nitrapyrin,relative to the treatment with urea alone,which was possibly due to N saving,lower N loss,and increased N uptake in the form of ammonium;they were further enhanced in the treatment with urea,nitrapyrin,and GA_3 by 27%,36%,and 25%,respectively,probably because of the stimulating effect of GA_3 on plant growth and development and the reduction in biotic and abiotic *** results suggest that applying urea in combination with nitrapyrin and GA_3 has the potential to mitigate N_(2)O emission,improve N response efficiency,and increase maize yield.

关键词： fertilizer use efficiency greenhouse gas emission mitigation N response efficiency N uptake efficiency N_(2)O flux plant growth hormone urea

Modeling of Heat Transfer and Steam Condensation Inside a Horizontal Flattened Tube

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Fluid Dynamics & Materials Processing 2022年第4期18卷 985-998页

作者： M.Gh.Mohammed kamil M.S.Kassim R.A.Mahmood L.AZ Mahdi Mechanical Engineering Department Faculty of EngineeringMustansiriyah UniversityBaghdad10052Iraq School of Mechanical and Electrical Engineering University of Southern QueenslandQueensland4350Australia Engineering Collage University of ZakhoZakho42002Iraq Energy and Renewable Energies Technology Center University of TechnologyBaghdad10066Iraq

This work investigates the steam condensation phenomena in an air-cooled *** considered horizontal flattened tube has a 30 mm hydraulic diameter,and its length is a function of the steam quality with a limit value between 0.95 and *** mass flow rate ranges from 4 to 40 kg/m^(2).s with a saturated temperature spanning an interval from 40°C to 80°C.A special approach has been implemented using the Engineering Equation Solver(EES)to solve a series of equations for the two-phase flow pattern and the related heat transfer coefficients.A wavy-stratified structure of the two-phase flow has been found when the mass rate was between 4 and 24 kg/m^(2).*** contrast,an initially annular flow is gradually converted into a wavy stratified flow(due to the condensation process taking place inside the flattened tube)when the considered range ranges from 32 to 40 kg/m^(2).s.

关键词： Condensation flow pattern structure heat transfer rate flow in horizontal pipe flow behaviour EES modelling