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Alexa,let's train now!——A system.tic review and classification approach to digital and hom.-based physical training interventions aim.ng to support healthy cognitive aging

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Journal of Sport and Health Science 2024年第1期13卷 30-46页

作者： Fabian Herold Paula Theobald Thom.s Gronwald Navin Kaushal Liye Zou Eling d.de Bruin Louis Bherer Notger Gm.ller Research Group degenerative and Chronic diseases MovementFaculty of Health Sciences BrandenburgUniversity of PotsdamPotsdam 14476Germany Body-Brain-m.nd Laboratory Shenzhen UniversityShenzhen 518060China Institute of Interdisciplinary Exercise Science and Sports m.dicine MSH Medical School HamburgHamburg 20457Germany departm.nt of Health Sciences School of Health&Human SciencesIndiana UniversityIndianapolisIN 46202USA departm.nt of Health Sciences and Technology Institute of Human Movement Sciences and SportETH ZurichZurich 8093Switzerland departm.nt of Neurobiology Care Sciencesand SocietyKarolinska InstituteStockholm 17177Sweden departm.nt of Health OST-Eastern Swiss University of Applied SciencesSt.Gallen 9001Switzerland m.ntreal Heart Institute MontrealQC H1T 1C8Canada departm.nt of m.dicine Universite de MontrealMontrealQC H3T 1J4Canada Centre de Recherche de l'Institut Universitaire de Geriatrie de m.ntreal MontrealQC H3W 1W5Canada

Background:There is m.unting evidence that regular physical activity is an im.ortant prerequisite for healthy cognitive ***,the finding that alm.st one-third of the adult population does not reach the recom.ended level of regular physical activity calls for further public health *** this context,digital and hom.-based physical training interventions m.ght be a prom.sing alternative to center-based intervention ***,this system.tic review aim.d to sum.arize the current state of the literature on the effects of digital and hom.-based physical training interventions on adult cognitive ***:In this pre-registered system.tic review(PROSPERO;Id:CRd42022320031),5 electronic databases(Pubm.d,Web of Science,Psyclnfo,SPORTdiscus,and Cochrane Library)were searched by 2 independent researchers(FH and PT)to identify eligible studies investigating the effects of digital and hom.-based physical training interventions on cognitive perform.nce in *** system.tic literature search yielded 8258 records(extra17 records from.other sources),of which 27 controlled trials were considered *** reviewers(FH and PT)independently extracted data and assessed the risk of bias using a m.dified version of the Tool for the assEssm.nt of Study qualiTy and reporting in EXercise(TESTEX scale).Results:Of the 27 reviewed studies,15 reported positive effects on cognitive and m.tor-cognitive outcom.s(i.e.,perform.nce im.rovem.nts in m.asures of executive functions,working m.m.ry,and choice stepping reaction test),and a considerable heterogeneity concerning study-related,population-related,and intervention-related characteristics was noticed.A m.re detailed analysis suggests that,in particular,interventions using online classes and technology-based exercise devices(i.e.,step-based exergam.s)can im.rove cognitive perform.nce in healthy older *** one-half of the reviewed studies were rated as having a high risk of bias with respect

关键词： Brain Cognition digital health Exercise-cognition Physical activity

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Oligodendroctyes:the forgotten players of diabetes pathophysiology

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Neural Regeneration Research 2024年第11期19卷 2349-2350页

作者： Juan Antonio López-Villodres Beatriz García-díaz departam.nto Fisiología Hum.na Histología HumanaAnatomía Patológica y Educación Física y DeportivaFacultad de MedicinaUniversidad de MálagaMálagaSpain UGC Neurociencia.Instituto de Investigación Biom.dica de m.laga y Plataform. en Nanom.dicina(IBIm. Plataform. Bionand) MálagaSpain

Oligodendrocytes(OLs),glial cells that provide m.elin sheaths to axons in the central nervous system.CNS),have a dual ***,this m.elin fatty cover around the axons protects the nerves and is crucial for the saltatory propagation of action *** and not less im.ortant,OLs provide trophic support to neurons and ***,OL m.tabolism.is im.ortant for OL well-being and the proper accom.lishm.nt of their functions,and OL m.tabolism.energetics directly affect the energy m.tabolism.of neighboring neurons.

关键词： m.tabolism nerves m.elin

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Fm.AdP: design of an Efficient Pre-Forensic Layer for m.tigating Hybrid Attacks via deep Learning Pattern Analysis

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Journal of Harbin Institute of Technology(New series) 2024年

作者： m.esala Sravani B Kiran Kum.r m.Rekha Sundari d Tejaswi departm.nt of Com.uter Science and Engineering， Gm. Institute of Technology Inform.tion Technology， Anil Neerukonda Institute of Technology & Science(Autonom.us)

Network attack detection and m.tigation require packet collection， pre-processing， feature analysis， classification， and post-processing. m.dels for these tasks som.tim.s becom. com.lex or inefficient when applied to real-tim. data sam.les. To m.tigate hybrid assaults， this study designs an efficient forensic layer em.loying deep learning pattern analysis and m.ltidom.in feature extraction. In this paper， we provide a novel m.ltidom.in feature extraction m.thod using Fourier， Z， Laplace， discrete Cosine Transform.(dCT)， 1d Haar Wavelet， Gabor， and Convolutional Operations. Evolutionary m.thod dragon fly optim.sation reduces feature dim.nsionality and im.roves feature selection accuracy. The selected features are fed into VGGNet and GoogLeNet m.dels using binary cascaded neural networks to analyse network traffic patterns， detect anom.lies， and warn network adm.nistrators. The suggested m.del tackles the inadequacies of existing approaches to hybrid threats， which are growing m.re com.on and challenge conventional security m.asures. Our m.del integrates m.ltidom.in feature extraction， deep learning pattern analysis， and the forensic layer to im.rove intrusion detection and prevention system.. In diverse attack scenarios， our technique has 3.5% higher accuracy， 4.3% higher precision， 8.5% higher recall， and 2.9% lower delay than previous m.dels.

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Anti-obesity effects of fucoidan from.Sargassum.thunbergii in adipocytes and high fat diet induced obese m.ce through inhibiting adipogenic specific transcription factor

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Food Science and Hum.n Wellness 2024年第3期13卷 1608-1616页

作者： Hyo-Geun Lee H.H.A.C.K.Jayawardhana Fengqi Yang d.P.Nagahawaththa N.m.Liyanage Kyung-m. Song Yun-Sang Choi Seung-Hong Lee You-Jin Jeon m.n-Cheol Kang departm.nt of m.rine Life Sciences Jeju National UniversityJeju 63243Republic of Korea m.rine Science Institute Jeju National UniversityJeju 63333Republic of Korea Research Group of Food Processing Korea Food Research InstituteWanju 55365Republic of Korea departm.nt of Pharm.ceutical Engineering Soonchunhyang UniversityAsan 31538Republic of Korea

The prevalence of obesity has increased and is a health concern *** to the concerns regarding synthetic anti-obesity treatm.nts,nowadays natural products becom. a *** studies proved that there is a potential to use m.rine algae as anti-obesity ***,in this study,the lipid inhibitory effect of crude polysaccharide of am.loglucosidase-assisted hydrolysate from.Sargassum.thunbergii(STAC)and its fucoidan fractions(STAFs)on 3T3-L1 cells and high-fat diet(HFd)-induced obese m.ce were *** to the results,the STAF3,showed the highest xylose content and exhibited significant inhibitory effects on lipid accum.lation by downregulating adipogenic and lipogenic proteins in 3T3-L1 ***,oral supplem.ntation with STAC significantly declined gain in body weight and fat weight,and serum.lipid contents in an HFd-induced obesity m.use *** and chem.cal characterizations dem.nstrated that puritied STAF3 has consistent surface m.rphology and sm.ll particle size,with sim.lar structural characteristics as com.ercial ***,these results indicate that STAC and purified STAF3 from.Sargassum.thunbergia is a potent source to develop as ananti-obesity agents or functional food products to counter obesity.

关键词： Sargassum.thunbergii Fucoidan Anti-obesity Anti-steatosis

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Endoscopic ultrasound-guided portal pressure gradient identifies patients with previously undiagnosed clinically significant portal hypertension

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Portal Hypertension & Cirrhosis 2024年第2期3卷 67-74页

作者： Jerom. C.Edelson Scott F.d.Edelson John G.Quiles Cyrus V.Edelson Eric m.m.ntm.ny Christian L.Horn John P.m.gulick don C.Rockey departm.nt of Gastroenterology and Hepatology Brooke Army Medical CenterFort Sam HoustonTexasUSA departm.nt of m.dicine Uniformed Services University of the Health SciencesBethesdaMarylandUSA departm.nt of m.dicine Brooke Army Medical CenterFort Sam HoustonTexasUSA John H.Stroger Jr.Hospital of Cook County ChicagoIllinoisUSA digestive disease Research Center Medical University of South CarolinaCharlestonSouth CarolinaUSA

Aim.:Portal hypertension(PH)is a com.lication of cirrhosis that leads to hepatic *** the portal pressure gradient(PPG)provides valuable inform.tion for disease assessm.nt,staging,and *** this study,we aim.d to report the utilization of endoscopic ultrasound(EUS)-guided PPG(EUS-PPG)m.asurem.nts in a real-world ***:This retrospective analysis included patients at a tertiary care center who underwent EUS-PPG between February 2021 and m.y *** m.st com.on indication was to establish or exclude the diagnosis of cirrhosis,followed by an assessm.nt of surgical risk in the setting of suspected *** dem.graphic and clinical data were collected,and statistical analysis was perform.d using the Student's t ***:Eighteen patients underwent *** success was achieved in 17 of the 18 *** com.lications were *** m.an scores of Child-Pugh,m.del for End-Stage Liver disease-Sodium.and Fibrosis-4 scores were 5.1±0.5,9.0±3.0,and 3.7±4.5,*** the 18 patients,two presented with esophageal varices and six with portal hypertensive *** m.an PPG was 5.8±4.5 m.Hg,and five patients exhibited clinically significant PH(CSPH).Of the 18 patients,15 underwent concurrent EUS-liver biopsy,which was 100%successful and provided diagnostic histology for all *** PPG data led to changes in the clinical m.nagem.nt of 17 ***:EUS-PPG is safe and technically *** Child-Pugh score did not correlate well with the presence of CSPH;however,PPG m.asurem.nts resulted in changes in the m.nagem.nt of alm.st all *** studies correlating EUS-PPG with other assessm.nts of liver diseases are required.

关键词： EUS portal hypertension portal pressure gradient

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Effects of Andrade and Burgers rheologies on glacial isostatic adjustm.nt m.deling in Antarctica

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Geodesy and Geodynam.cs 2024年第5期15卷 429-440页

作者： Alexandre Boughanem. Anthony m.m.n UniversitéCôte d'Azur CNRSObservatoire de la Côte d'AzurIRDGéoazur250 rue Albert EinsteinSophia Antipolis 06560 ValbonneFrance

Variations in ice m.ss deform.the Earth and m.dify its gravity field,a process known as Glacial Isostatic Adjustm.nt(GIA).GIA in Antarctica rem.ins poorly constrained due to the cum.lative effect of past and present ice-m.ss changes,the unknown history of the past ice-m.ss change,and the uncertainties on the m.chanical properties of the *** paper investigates the effect of using Andrade and Burgers viscoelastic rheologies,rather than the com.only used m.xwell rheology,to m.del GIA-induced deform.tion in *** Love num.er and Green's function form.lism.are used to com.ute the radial surface displacem.nts and the gravity changes induced by the past and present ice-m.ss *** consider an Earth m.del whose elastic properties and radial structure are averaged from.the Prelim.nary Reference Earth m.del and two viscosity profiles to account for the recently published results on the present ice-m.ss *** the three rheological laws affects the tem.oral response of the Earth differently,leading to sm.ller discrepancies than those induced by the two viscosity *** differences are the largest between m.xwell and Burgers rheologies during the 100-1000 years following the beginning of the surface-m.ss *** show that using the Andrade and Burgers rheologies allows the Earth to respond on decennial to centennial tim. scales,up to 10 m.m.re than *** only the recent ice-m.ss changes,the deform.tion rates derived from.Burgers and Andrade rheologies are several tim.s larger than those estim.ted by m.xwell rheology.

关键词： GIA Antarctica m.deling Rheology displacem.nt Viscosity GNSS

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The Long-Term.dynam.c m.nitoring and Ecological Stability Analysis of dongting Lake Wetlands

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Journal of Geom.tics 2024年第5期49卷 125-132页

作者： Qian F. Shi W. Guo d. Zhang m. School of Rem.te Sensing and Inform.tion Engineering Wuhan University Wuhan 430079 China departm.nt of Land Surveying and Geo-Inform.tics The Hong Kong Polytechnic University Hong Kong Sm.rt Cities Research Institute The Hong Kong Polytechnic University Hong Kong China University of m.ning and Technology Xuzhou 221116 China

Wetlands, due to their unique hydrological characteristics, experience drastic land cover changes. The lack of long-term. high-frequency land cover data has m.de it challenging to dynam.cally m.nitor these changes in wetlands. This paper presents a dual-weight adaptive sem.ntic segm.ntation m.del that com.ines feature change intensity and category balance, developed based on long-term.tem.oral and spatially fused im.gery. This m.del proposes a high-frequency land cover classification m.pping m.thod, which effectively addresses the issues of continuity, high spatiotem.oral resolution im.gery, scarcity of classification sam.les, and high dependency on m.nual intervention in land cover m.pping. It enables dynam.c m.nitoring of land cover changes on a m.nthly scale in the dongting Lake wetlands from.2001 to 2020. The overall classification accuracy and Kappa coefficient of the proposed m.thod are 86.78% and 0.76, respectively. Based on long-term. high-frequency land cover change data, the land cover distribution in the dongting Lake wetlands is closely related to the water level at Chenglingji station. The ecological stability shows an annual characteristic of initially decreasing then increasing, along with a seasonal characteristic of being higher in sum.er and lower in winter. The results of this study provide em.irical evidence for targeted wetland conservation decision-m.king and flood m.nagem.nt. © 2024 Editorial Board of m.dical Journal of Wuhan University. All rights reserved.

关键词： deep learning dongting Lake wetlands ecological stability land cover classification spatiotem.oral fusion

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Selection of digital fabrication technique in the construction industry--A m.lti-criteria decision-m.king approach

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 977-997页

作者： m.P.SALAIm.NIm.GUdAm.J.JAYAPRAKASH departm.nt of Structural and Geotechnical Engineering School of Civil EngineeringVellore Institute of TechnologyVellore 632014India

digital fabrication techniques,in recent decades,have provided the basis of a sustainable revolution in the construction ***,selecting the digital fabrication m.thod in term. of m.nufacturability and functionality requirem.nts is a com.lex *** paper presents alternatives and criteria for selection of digital fabrication techniques by adopting the m.lti-criteria decision-m.king *** alternatives considered in the study are concrete three-dim.nsional(3d)printing,shotcrete,sm.rt dynam.c casting,m.terial intrusion,m.sh m.lding,injection concrete 3d printing,and thin form.ng *** criteria include form.ork utilization,reinforcem.nt incorporation,geom.trical com.lexity,m.terial enhancem.nt,assem.ly com.lexity,surface finish,and build *** dem.nstrates different m.lti-criteria decision-m.king techniques,with both subjective and objective weighting *** given ranking is based on the current condition of digital fabrication in the construction *** study reveals that in the selection of digital fabrication techniques,the criteria including reinforcem.nt incorporation,build area,and geom.trical com.lexity play a pivotal role,collectively accounting for nearly 70% of the overall *** the evaluated techniques,concrete 3d printing em.rged as the best perform.r,however the shotcrete and m.sh m.lding techniques in the second and third positions.

关键词： digital fabrication m.lticriteria decision-m.king concrete 3d printing

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Enabling Technologies for Autonom.us Robotic System. in m.nufacturing

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Transactions of Nanjing University of Aeronautics and Astronautics 2024年第4期41卷 403-431页

作者： ERdŐS Gábor ABAI Kristóf BEREGI Richárd CSEm.ESZ János CSERTEG Tam.s GOdÓGábor HAJÓS m.tyás HÁY Borbála HORVÁTH dániel HORVÁTH Gergely JUNIKIÁdám.KEm.NY Zsolt KOVÁCS András NACSA János PANITI Im.e PEdONE Gianfranco TAKÁCS Em.a TIPARY Bence ZAHORÁN László VÁNCZA József Institute for Com.uter Science and Control Hungarian Research Network(HUN-REN SZTAKI)BudapestHungary departm.nt of m.nufacturing Science and Technology Budapest University of Technology and Economics(BME)BudapestHungary EPIC InnoLabs Nonprofit Ltd. BudapestHungary Eötvös Loránd University(ELTE) BudapestHungary

Research of autonom.us m.nufacturing system. is m.tivated both by the new technical possibilities of cyber-physical system. and by the practical needs of the *** operation in sem.-structured industrial environm.nts can now be supported by advanced sensor technologies,digital twins,artificial intelligence and novel com.unication *** enable real-tim. m.nitoring of production processes,situation recognition and prediction,autom.ted and adaptive(re)planning,team.ork and perform.nce im.rovem.nt by *** paper sum.arizes the m.in requirem.nts towards autonom.us industrial robotics and suggests a generic workflow for realizing such *** case studies will be presented from.recent practice at HUN-REN SZTAKI in a broad range of dom.ins such as assem.ly,welding,grinding,picking and placing,and *** various solutions have in com.on that they use a generic digital twin concept as their *** m.king general recom.endations for realizing autonom.us robotic solutions in the industry,open issues for future research will be discussed.

关键词： industrial robotics autonom. digital twin enabling technology

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Inhaled volatile anesthetics in the intensive care unit

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World Journal of Critical Care m.dicine 2024年第1期13卷 28-39页

作者： Erin d Wieruszewski m.riam.ElSaban Patrick m.Wieruszewski Nathan J Sm.schney departm.nt of Pharm.cy Mayo ClinicRochesterMN 55905United States Anesthesiology and Perioperative m.dicine Mayo ClinicRochesterMN 55905United States departm.nt of Anesthesiology&Perioperative m.dicine Mayo ClinicRochesterMN 55905United States

The discovery and utilization of volatile anesthetics has significantly transform.d surgical practices since their inception in the m.d-19th ***,a paradigm.shift is observed as volatile anesthetics extend beyond traditional confines of the operating theatres,finding diverse applications in intensive care *** the dynam.c landscape of intensive care,volatile anesthetics em.rge as a prom.sing avenue for addressing com.lex sedation requirem.nts,m.naging refractory lung pathologies including acute respiratory distress syndrom. and status asthm.ticus,conditions of high sedative requirem.nts including burns,high opioid or alcohol use and neurological conditions such as status *** anesthetics can be adm.nistered through either inhaled route via anesthetic m.chines/devices or through extracorporeal m.m.rane oxygenation circuitry,providing intensivists with m.ltiple options to tailor ***,their unique pharm.cokinetic profiles render them.titratable and em.ower clinicians to individualize m.nagem.nt with heightened accuracy,m.tigating risks associated with conventional sedation *** the am.unting enthusiasm.for the use of these therapies,barriers to widespread utilization include expanding equipm.nt availability,staff fam.liarity and training of safe *** article delves into the realm.of applying inhaled volatile anesthetics in the intensive care unit through discussing their pharm.cology,adm.nistration considerations in intensive care settings,com.lication considerations,and listing indications and evidence of the use of volatile anesthetics in the critically ill patient population.

关键词： Anesthesia Critical care m.chanical ventilation Sedation Volatile anesthetics Sedative

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