检索结果-南通市图书馆

Sex hormones in the modulation of irritable bowel syndrome

World Journal of Gastroenterology 2014年第10期20卷 2433-2448页

作者： agata Mulak Yvette Taché Muriel Larauche Department of Gastroenterology and Hepatology Wroclaw Medical University 50-556 Wroclaw Poland CURE:Digestive Diseases Research Center and Oppenheimer Family Center for Neurobiology of Stress Digestive Diseases Division Department of MedicineUniversity of California Los Angeles VA Greater Los Angeles Healthcare System Los Angeles CA 90073 United States

Compelling evidence indicates sex and gender differences in epidemiology, symptomatology, pathophysiology, and treatment outcome in irritable bowel syndrome (IBS). Based on the female predominance as well as the correlation between IBS symptoms and hormonal status, several models have been proposed to examine the role of sex hormones in gastrointestinal (GI) function including differences in GI symptoms expression in distinct phases of the menstrual cycle, in pre- and post-menopausal women, during pregnancy, hormonal treatment or after oophorectomy. Sex hormones may influence peripheral and central regulatory mechanisms of the brain-gut axis involved in the pathophysiology of IBS contributing to the alterations in visceral sensitivity, motility, intestinal barrier function, and immune activation of intestinal mucosa. Sex differences in stress response of the hypothalamic-pituitary-adrenal axis and autonomic nervous system, neuroimmune interactions triggered by stress, as well as estrogen interactions with serotonin and corticotropin-releasing factor signaling systems are being increasingly recognized. A concept of “microgenderome” related to the potential role of sex hormone modulation of the gut microbiota is also emerging. Significant differences between IBS female and male patients regarding symptomatology and comorbidity with other chronic pain syndromes and psychiatric disorders, together with differences in efficacy of serotonergic medications in IBS patients confirm the necessity for more sex-tailored therapeutic approach in this disorder.

关键词： Brain-gut axis Irritable bowel syndrome Microbiota Pain modulation Sex hormones

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The influence of in ovo injection with the prebiotic DiNovoon the development of histomorphological parameters of the duodenum, body mass and productivity in large-scale poultry production conditions

引用

Journal of Animal Science and Biotechnology 2017年第4期8卷 984-991页

作者： Adrianna Sobolewska Gabriela Elminowska-Wenda Joanna Bogucka agata Dankowiakowska Anna Kulakowska agata Szczerba Katarzyna Stadnicka Michal Szpinda Marek Bednarczyk Department of Animal Biochemistry and Biotechnology University of Science and Technology in Bydgoszcz Mazowiecka 28 Street 85-084 Bydgoszcz Poland Department of Normal Anatomy the Ludwik Rydygier Collegium Medicum in Bydgoszcz the Nicolaus Copernicus University in Torun 24 Karlowicza Street Bydgoszcz 85-092 Poland

Background: Among various feed additives currently used in poultry nutrition, an important role is played by bioactive substances, including prebiotics. The beneficial effect of these bioactive substances on the gastrointestinal tract and immune system give rise to improvements in broiler health and performance nutrition, thus increasing the productivity of these birds. An innovative method for introducing bioactive substances into chickens is the in ovo injection into eggs intended for hatching. The aim of the study was to evaluate the development of histomorphological parameters of the duodenum and productivity in chickens injected in ovo with the prebiotic DiNovo~?(extract of Laminaria species of seaweed, BioA tlantis Ltd., Ireland) on d 12 of incubation, under large-scale, high density poultry production ***: There was no significant impact of the injection of DiNovo~? prebiotic on the production parameters of broiler chickens(body weight, FCR, EBI and mortality) obtained on d 42 of rearing. No significant impact of the DiNovo~? injection on the duodenum weight and length was observed, as wel as on the CSA, diameter and muscular layer thickness of the duodenum. The in ovo injection of DiNovo~? significantly increased the width of the duodenal vil i(P < 0.05) and crypt depth(P < 0.01) of chickens on d 21 of rearing. Other histomorphological parameters of duodenal vil i at d 42 of chickens rearing such as: the height, width, and cross section area of vil i were significantly greater in chickens from the control group compared to those from the DiNovo~? group(P < 0.05 and P < 0.01).Conclusions: In conclusion, this study demonstrates that injection of DiNovo~? prebiotic into the air chamber of egg significantly influences the histomorphological parameters on d 21 of rearing without negatively affecting productivity in chickens at the end of rearing.

关键词： Chicken Duodenum Histomorphological parameters In ovo Prebiotic Productivity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Coarse woody debris and wood-colonizing fungi differences between a reserve stand and a managed forest in the Taborz region of Poland

引用

Journal of Forestry Research 2019年第3期30卷 1081-1091页

作者： Slwomir Pieeka agata Sotnik Marta Damszel Zbigniew Sierota Department of Forestry and Forest Ecology Warmia and Mazury University in OlsztynPl.Lodzki 210-727 Olsztyn Poland Milomlyn Forest District Nadlesna 914-140 Milomlyn Poland Department of Entomology Phytopathology and Molecular DiagnosticsWarmia and Mazury University in Olsztyn Prawochen′skiego 1710-721 OlsztynPoland

The aim of this research was to evaluate the amount of woody debris (m3/ha) on the forest floor and the associated wood-colonizing fungi. The study was performed in the Taborz region, known for its Scots pine provenance experiments, against the background of a recently launched Polish legislation to protect the biodiversity on the forest floor in managed (harvested) stands. We investigated a managed stand (136-years-old) and the reserve stand ‘Sosna Taborska’(261-years-old). In the reserve stand, the mean volume of woody debris was six times higher than in the managed forests, i.e. 65 versus 11 m3/ha. In addition, in the reserve stand, the number of fungi taxa colonizing the dead wood was larger than in the managed stands, with a higher number of fruitbodies. Total fungal richness was higher in the reserve than in the managed stand, i.e. 28 versus 12 species. The dominant taxa at both sites were Fomitopsis pinicola and Fomes The aim of this research was to evaluate the amount of woody debris (m^3/ha) on the forest floor and the associated wood-colonizing fungi. The study was performed in the Taborz region, known for its Scots pine provenance experiments, against the background of a recently launched Polish legislation to protect the biodiversity on the forest floor in managed (harvested) stands. We investigated a managed stand (136-years-old) and the reserve stand ‘Sosna Taborska’(261-years-old). In the reserve stand, the mean volume of woody debris was six times higher than in the managed forests, i.e. 65 versus 11 m^3/ha. In addition, in the reserve stand, the number of fungi taxa colonizing the dead wood was larger than in the managed stands, with a higher number of fruitbodies. Total fungal richness was higher in the reserve than in the managed stand, i.e. 28 versus 12 species. The dominant taxa at both sites were Fomitopsis pinicola and Fomes fomentarius, although some taxa were only found in the reserve (e.g., Stereum hirsutum). The volume of woody debris as w

关键词： Coarse woody debris Fungi Managed (harvested) stands Reserve Sosna Taborska Reserve Forest Indices

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Kitchen waste valorization through a mildtemperature pretreatment to enhance biogas production and fermentability:Kinetics study in mesophilic and thermophilic regimen

引用

Journal of Environmental Sciences 2020年第3期32卷 167-179页

作者： agata Gallipoli Camilla MBraguglia Andrea Gianico Daniele Montecchio Pamela Pagliaccia Water Research Institute IRSA-CNR Area Della Ricerca RM100015 MonterotondoRomaItaly

Biowaste valorization through anaerobic digestion is an attractive option to achieve both climate protection goals and renewable energy *** this paper,a complete set of batch trials was carried out on kitchen waste to investigate the effects of mild thermal pretreatment,temperature regimen and substrate/inoculum *** pretreatment was effective in the solubilisation of macromolecular fractions,particularly *** ability of the theoretical methodologies in estimating hydrogen and methane yields of complex substrates was evaluated by comparing the experimental results with the theoretical *** the single batch configuration,a significant initial hydrogen production was observed,prior to methane *** pretreatment effect was the gain in hydrogen production;the extent was highly variable according to the other parameters *** hydrogen yields,up to 113 mL H2/g VSfed,were related to the prompt transformation of soluble *** regimen resulted,as expected,in faster digestions(up to 78 mL CH4/gVS/day) and sorted out pH *** relatively low methane yields(342-398 mL CH4/g VSfed) were the result of the consistent lignocellulosic content and low lipid *** pretreatment proved to be a promising option for the enhancement of hydrogen production in food waste dark fermentation.

关键词： Kitchen waste Hydrogen Methane Thermal pretreatment Kinetics Thermophilic regimen

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Novel synthesis method combining a foaming agent with freeze-drying to obtain hybrid highly macroporous bone scaffolds

引用

Journal of Materials Science & Technology 2020年第8期36卷 52-63页

作者： Paulina Kazimierczak Aleksandra Benko Krzysztof Palka Cristina Canal Dorota Kolodynska agata Przekora Department of Biochemistry and Biotechnology Medical University of LublinChodzki 120-093LublinPoland AGH University of Science and Technology Faculty of Materials Science and CeramicsA.Mickiewicza 30 Ave.30-059KrakowPoland Department of Materials Engineering Lublin University of TechnologyNadbystrzycka 3620-618LublinPoland Biomaterials Biomechanics and Tissue Engineering GroupDepartment of Materials Science and MetallurgyUniversitat Politècnica de CatalunyaBarcelona08019Spain Research Centre in Multiscale Science and Engineering Universitat Politècnica de CatalunyaBarcelona08019Spain Department of Inorganic Chemistry Maria Curie-Sklodowska UniversityMaria Curie Sklodowska Sq.220-031LublinPoland

Three-dimensional macroporous scaffolds are commonly used in bone tissue engineering applications since they provide sufficient space for cell migration and proliferation, facilitating bone ingrowth and implant vascularisation. The aim of this work was to combine two simple methods, freeze-drying and gas-foaming, in order to fabricate highly macroporous bone scaffolds made of chitosan/agarose matrix reinforced with nanohydroxyapatite. The secondary goal of this research was to comprehensively assess biomedical potential of developed biomaterials. In this work, it was demonstrated that simultaneous application of freeze-drying and gas-foaming technique allows to obtain hybrid(as proven by ATR-FTIR)macroporous bone scaffolds(pore diameter > 50 um) characterized by high open(70%) and interconnected porosity. Novel scaffolds were non-toxic, favoured osteoblasts adhesion and growth and induced apatite formation on their surfaces, indicating their high bioactivity that is essential for good implant osseointegration. Biomaterials were also prone to enzymatic degradation, degradation in acidified microenvironment(e.g. osteoclast-mediated), and slow degradation under physiological p H of ***, the scaffolds revealed microstructure(70% open porosity, SSA approx. 30 m2/g, high share of macropores with diameter in the range 100-410 um) and compressive strength(1–1.4 MPa) comparable to cancellous bone, indicating that they are promising implants for cancellous bone regeneration.

关键词： Agarose Chitosan Nanohydroxyapatite Biomaterial porosity Biodegradation Cryogel

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The plant N-degron pathways of ubiquitinmediated proteolysis

引用

Journal of Integrative Plant Biology 2020年第1期62卷 70-89页

作者： Michael John Holdsworth Jorge Vicente Gunjan Sharma Mohamad Abbas agata Zubrycka School of Biosciences University of Nottingham

The amino-terminal residue of a protein(or amino-terminus of a peptide following protease cleavage)can be an important determinant of its stability,through the Ubiquitin Proteasome System associated N-degron *** contain a unique combination of N-degron pathways(previously called the N-end rule pathways)E3 ligases,PROTEOLYSIS(PRT)6 and PRT1,recognizing non-overlapping sets of amino-terminal residues,and others remain to be *** only very few substrates of PRT1 or PRT6 have been identified,substrates of the oxygen and nitric oxide sensing branch of the PRT6 N-degron pathway include key nuclear-located transcription factors(ETHYLENE RESPONSE FACTOR VIIs and LITTLE ZIPPER 2)and the histone-modifying Polycomb Repressive Complex 2 component VERNALIZATION *** response to reduced oxygen or nitric oxide levels(and other mechanisms that reduce pathway activity)these stabilized substrates regulate diverse aspects of growth and development,including response to flooding,salinity,vernalization(cold-induced flowering)and shoot apical meristem *** N-degron pathways show great promise for use in the improvement of crop performance and for biotechnological *** proteases,components of the different pathways and associated substrates still remain to be identified and characterized to fully appreciate how regulation of protein stability through the amino-terminal residue impacts plant biology.

关键词： stability residue cleavage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hepatitis C virus reinfection after liver transplantation: Is there a role for direct antiviral agents?

引用

World Journal of Gastroenterology 2014年第28期20卷 9253-9260页

作者： Marco Dall’agata Annagiulia Gramenzi Maurizio Biselli Mauro Bernardi Semeiotica Medica - Policlinico S.Orsola-Malpighi Dipartimento di Scienze Mediche e ChirurgicheUniversity of Bologna

Recurrence of hepatitis C virus(HCV)infection following liver transplantation(LT)is almost universal and can accelerate graft cirrhosis in up to 30%of *** development of effective strategies to treat or prevent HCV recurrence after LT remains a major challenge,considering the shortage of donor organs and the accelerated progression of HCV in LT *** antiviral therapy with pegylated-interferon plus ribavirin is the current treatment of choice for HCV LT recipients,even though the combination is not as effective as it is in immunocompetent patients.A sustained virological response in the setting of LT improves patient and graft survival,but this is only achieved in 30%-45%of patients and the treatment is poorly *** improve the efficacy of pre-and post-transplant antiviral therapy,a new class of potent direct-acting antiviral agents (DAAs)has been *** aim of this review is to summarize the use of DAAs in LT HCV ***,Cochrane Library,MEDLINE,EMBASE,Web of Science and clinical trial databases were searched for this *** date,only three clinical studies on the topic have been published and most of the available data are in abstract *** a moderately successful early virological response has been reported,DAA treatment regimens were associated with severe toxicity mitigating their potential ***,the ongoing nature of data,the lack of randomized studies,the small number of enrolled patients and the heterogeneity of these studies make the results largely anecdotal and *** conclusion,large welldesigned clinical studies on DAAs in HCV LT patients are required before these drugs can be recommended after transplantation.

关键词： Hepatitis C virus Liver transplantation Direct antiviral agents Peginterferon/ribavirin Immunosuppressive agents

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The role of arabinogalactan proteins(AGPs)in fruit ripening—a review

引用

Horticulture Research 2020年第1期7卷 422-433页

作者： agata Leszczuk Panagiotis Kalaitzis Konstantinos N.Blazakis Artur Zdunek Institute of Agrophysics Polish Academy of SciencesDoświadczalna 420-290 LublinPoland Department of Horticultural Genetics and Biotechnology Mediterranean Agronomic Institute of ChaniaChaniaP.O.Box 85Chania 73100Greece

Arabinogalactan proteins(AGPs)are proteoglycans challenging researchers for ***,despite the extremely interesting polydispersity of their structure and essential application potential,studies of AGPs in fruit are limited,and only a few groups deal with this scientific ***,we summarise the results of pioneering studies on AGPs in fruit tissue with their structure,specific localization pattern,stress factors influencing their presence,and a focus on recent *** discuss the properties of AGPs,i.e.,binding calcium ions,ability to aggregate,adhesive nature,and crosslinking with other cell wall components that may also be implicated in fruit *** aim of this review is an attempt to associate well-known features and properties of AGPs with their putative roles in fruit *** putative physiological significance of AGPs might provide additional targets of regulation for fruit developmental programme.A comprehensive understanding of the AGP expression,structure,and untypical features may give new information for agronomic,horticulture,and renewable biomaterial applications.

关键词： AGPs structure culture

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Piezoresponse force microscopy and dielectric spectroscopy study of Ba_(0.6)Sr_(0.4)TiO_(3)thin films

引用

Journal of Advanced Dielectrics 2019年第3期9卷 29-35页

作者： Dionizy Czekaj agata Lisińska-Czekaj Department of Materials Engineering and Welding Faculty of Mechanical Engineering Gdansk University of Technology 11/12 Narutowicza St.Gdansk 80-233Poland

Research on synthesis,characterization and determination of processing-structure-property relationships of commercially important ferroelectric thin films has been *** sol-gel type solution deposition technique was applied to produce good quality thin films of Ba_(0.6)Sr_(0.4)TiO_(3)(BST60/40)chemical composition on the stainless steel *** thin films were characterized in terms of their microstructure,crystal structure,phase composition,piezoelectric and dielectric *** was found that the BST60/40 thin film adopted the cubic structure at room temperature with an elementary cell parameter a-3:971e8TÅ.Morphology of the thin film surface was studied with Atomic Force Microscopy(AFM).Average roughness of the thin films surface was found(Sa=0:055μm).Piezoresponse Force Microscopy(PFM)was applied for the thin film *** piezoelectric regions were found in BST60/40 thin ***,dielectric response measured at room temperature was studied in assumption of piezoelectric electric equivalent circuit.

关键词： Thin film Ba_(0.6)Sr_(0.4)TiO_(3) crystal structure dielectric spectroscopy piezoresponse force microscopy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Vases

Vases

引用

作者： agata Toromanoff.

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：