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Brazilian adolescents’lifestyle in the COVID‑19 pandemic:a mixed‑methods study

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World Journal of Pediatrics 2022年第8期18卷 553-557页

作者： Caroline lima fonseca Carolina Ferreira Peterle Bruna Hinnah Borges Martins de Freitas Maria Aparecida Munhoz Gaíva Paula Manuela Jorge Diogo Juliano Bortolini Federal University of Mato Grosso 2367 Fernando Corrêa da Costa AvBoa EsperançaCuiabáMT 78060-900Brazil Lisbon College of Nursing LisbonPortugal

The COVID-19 pandemic has forced the health authorities and governments worldwide to engage in a battle against the disease,adopting several mitigation strategies[1].Since then,the world population has been afected by various changes in its *** imposed by the COVID-19 pandemic are believed to have had an impact on adolescents'lifestyle(LS)[2].The LS is determined by discernible behavior patterns that can trigger efects on adolescents'health and is related to countless aspects that refect attitudes,values and life opportunities[3].Therefore,LS can be observed from the habits,behaviors and activities performed by people in their daily lives[4].

关键词： has routine COV

Soot combustion; Ceria; Ternary mixed oxide; Cordierite coating; Diesel particulate filter

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Journal of Environmental Sciences 2018年第11期30卷 58-68页

作者： Leandro Fontanetti Nascimento Juliana fonseca lima Paulo Cesar de Sousa Filho Osvaldo Antonio Serra department of Chemistry FFCLRP University of Sao Paulo 14040-901 Ribeirao Preto Sao Paulo Brazil Institute of Chemistry Rio de Janeiro State University 20550-900 Rio de Janeiro Rio de Janeiro Brazil Institute of Chemistry Uniuersity of Campinas 13083-970 Campinas Silo Paulo Brazil Center of-Natural and Human Sciences Federal Uniuerty of ABC 09210-580 Santo Andre Sao Paulo Brazil

We report the application of a solid lanthanum-ceria-zinc catalyst in the catalytic regeneration of diesel particulate filters （DPF） in diesel engines. We synthesized a CeO2- ZnO-La2O3 （Ce-Zn-La） mixed oxide by a lactic acid-mediated sol-gel method, which efficiently coated cordierite substrates for soot capture and combustion. We studied the effects of La loading on the physicochemical and catalytic properties of Ce-Zn mixed oxide during lowtemperature soot combustion processes. We characterized the synthesized catalysts by X-ray diffraction （XRD）, Fourier-transform infrared spectroscopy （FTIR）, N2 adsorption, Raman spectroscopy, oxygen storage capacity （OSG）, and scanning and transmission electron microscopy （SEM and TEM）. Thermogravimetric and differential thermal analysis （TGA/DTA） confirmed that the catalysts effectively reduced the soot oxidation temperature. The ternary Ce-Zn-La mixed oxide catalyst with Ce/Zn/La atomic ratio of 2：1：0.5 had the highest catalytic activity and promoted soot oxidation at temperatures below 390℃. This indicated that the large number of oxygen vacancies in the catalyst structure generated oxygen species at low temperatures. Raman spectroscopy measurements revealed the presence of oxygen vacancies and lattice defects in Ce-Zn-La samples, which were key parameters concerning the stability and redox properties of the prepared catalysts.

关键词： Soot combustion Ceria Ternary mixed oxide Cordierite coating Diesel particulate filter

Updates in the Diagnosis of Gestational Trophoblast Disease

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Health 2023年第1期15卷 48-58页

作者： Maira de lima Oliveira Mota Marcela Curvêllo Beltrão Elizabeth Bacha Eduardo fonseca Mascarenhas Filho Maísa Mendonça de Jesus Nelson Henriky Felix Mascarenhas Tallys Leandro barbosa da Silva Maria Fernanda Telles Pires de Souza Victoria de Oliveira Carmo Borges Séfora Maria Fragoso Braga Centro Universitário Tiradentes (UNIT) Maceió Brasil Estácio de Juazeiro do Norte (FMJ) Ceará Brasil Universidade Federal de Alagoas (UFAL) Maceió Brasil Sã o Leopoldo Mandic Campinas Brasil Hospital Regional de Arapiraca Arapiraca Brasil

GTD (Gestational Trophoblastic Disease) is a pathology that encompasses benign and malignant clinical forms, affects women of childbearing age, has a variable incidence and is more frequent in developing or underdeveloped countries, colliding with the economic barrier. The frequent absence of clear protocols and guidelines for the correct diagnosis of the pathology results in inadequate classification, imprecise treatment and failed post-therapeutic observation, increasing the risk of relapses, morbidity and mortality. The present study aims to point out updated national and international practice protocols of diagnosis of GTD, through an integrative review. Seven articles were selected and it was observed that the main international reference centers are agreed with the management suggested by the IFGO (International Federation of Gynecology and Obstetrics), being the conduct in the Hydatidiform Mole (HM): evacuation by suction and curettage under ultrasound guidance, followed by hCG monitoring every 1 - 2 weeks until normalized (usually one month for Partial Hydatidiform Mole six months for Complete Hydatidiform Mole and one year for Gestational Trophoblastic Neoplasia). Unfortunately, regarding the diagnosis of MH, the guidelines of some countries show the absence or difficulty of access to the karyotype test and ploid p57 or pelvic ultrasound accompanying the uterine curettage, contrary to what is proposed by the IFGO guideline. Establishing and complying with consistent guidelines can improve patient care, with early diagnosis of the pathology and its complications, reducing the rate of recurrence, morbidity and mortality, especially in less developed countries.

关键词： Diagnosis Gestational Trophoblastic Disease Updates

Intake,digestibility and nitrogen utilization in cattle fed tropical forage and supplemented with protein in the rumen,abomasum,or both

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Journal of Animal Science and Biotechnology 2016年第4期7卷 544-553页

作者： Luana Marta de Almeida Rufino Edenio detmann Daianyíris Gomes William lima Santiago dos Reis Erick Darlisson Batista Sebastiao de Campos Valadares Filho Mário fonseca Paulino department of Animal Science Universidade Federal de Viaosa department of Animal Science Universidade Federal Rural da Amaznia

Background： There is little information in the tropics with regard the comparative understanding of how an increased nitrogen supply in the rumen or in the intestines affects efficiency of nitrogen utilization in cattle. This study evaluated the effects of supplementation with nitrogenous compounds in the rumen, abomasum, or both on intake, digestibility and the characteristics of nitrogen utilization in cattle fed tropical forage. Four rumen- and abomasum-fistulated Nellore bulls （227 ± 11 kg） were used. Four treatments were evaluated： control, ruminal supplementation （230 g/d of supplemental protein in the rumen）, abomasal supplementation （230 g/d of supplemental protein in the abomasum）, and ruminal and abomasal supplementation （115 g/d protein in both the rumen and the abomasum）. The basal forage diet consisted of Tifton 85 hay with a crude protein （CP） level of 78.4 g/kg dry matter. Casein was used as a supplement. The experiment was conducted using a 4 x 4 Latin square. Results： There were no differences between the treatments （P 〉 0.10） with regard to forage intake. The intake and tota digestibility of CP increased （P 〈 0.01） with supplementation. The nitrogen balance in the body increased （P 〈 0.01） and muscle protein mobilization decreased （P 〈 0.01） with supplementation, regardless of the supplementation site. The efficiency of nitrogen utilization did not differ among the treatments （P 〉 0.10）. Conclusions： The supplementation of cattle fed tropical forage with protein in the rumen, abomasum, or both similarly increased the nitrogen accretion in animal, which reflects improvements on nitrogen status in animal body.

关键词： Casein Nitrogen balance Rumen ammonia nitrogen Supplementation 3-methylhistidine

Role of lysophosphatidic acid and its receptors in health and disease:novel therapeutic strategies

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Signal Transduction and Targeted Therapy 2021年第3期6卷 630-647页

作者： Luiz Henrique Medeiros Geraldo Tania Cristina Leite de Sampaio Spohr Rackele Ferreira do Amaral Anna Carolina Carvalho da fonseca Celina Garcia Fabio de Almeida Mendes Catarina Freitas Marcos Fabio dosSantos Flavia Regina Souza lima Institute de Ciencias BiomedicasUniversidade Federal do Rio de JaneiroRio de JaneiroBrazil Universite de Paris PARCCINSERMF-75015 ParisFrance Institute Estadual do Cerebro Paulo Niemeyer-Secretaria de Estado de Saude Rio de JaneiroBrazil Instituto de Saiide de Nova Friburgo Universidade Federal Fluminense28625-650 Nova FriburgoBrazil

Lysophosphatidic acid(LPA)is an abundant,bioactive phospholipid,with multiple functions both in development and in pathological ***,we review the literature about the differential signaling of LPA through its specific receptors,which makes this lipid a versatile signaling *** differential signaling is important for understanding how this molecule can have such diverse effects during central nervous system development and angiogenesis;and also,how it can act as a powerful mediator of pathological conditions,such as neuropathic pain,neurodegenerative diseases,and cancer ***,we review the preclinical and clinical uses of Autotaxin,LPA,and its receptors as therapeutic targets,approaching the most recent data of promising molecules modulating both LPA production and *** review aims to summarize the most update knowledge about the mechanisms of LPA production and signaling in order to understand its biological functions in the central nervous system both in health and disease.

关键词： therapeutic clinical diseases

Chemical Composition and Nutritional Evaluation of Cake Made with Flour Mixture of Pigeonpea and Rice

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Food and Nutrition Sciences 2021年第11期12卷 1164-1176页

作者： Ferlando lima Santos Wagna Santos Bruna Machado Karina fonseca Merian Oliveira adriana Nascimento Federal University of Reconcavo da Bahia (UFRB) Cruz das Almas Brazil

This study aimed to develop and characterize a cake based on a flour mixture of pigeonpea and rice. Four cake formulations of different percentages of pigeonpea flour (PF) and Rice Flour (RF) (0% PF + 100% RF, 10% PF + 90% RF, 20% PF + 80% RF, 30% PF + 70% RF) were developed based on a traditional formulation. Microbiological, physicochemical and sensory evaluations were performed. The tasters preferred the mix formulation containing 30% pigeonpea and 70% rice (p dequate physicochemical and microbiological characteristics. The study also showed 90% acceptance and 70% purchase intention by the tasters. It is concluded that the use of a flour mixture of pigeonpea and rice allows an innovative, nutritious product, with good acceptance and technological potential. This product meets the needs of the food industry, such as: 1) it is gluten-free;2) contributes for the adoption of healthy eating habits;3) promotes family farming;and 4) stimulates the consumption of regional vegetables that can be incorporated into school meals menus, rescuing the consumption habits of rice and beans and eventually valuing the traditional Brazilian diet. It is worth noting the low lipid, high fiber, iron and zinc content characteristic of the developed product.

关键词： Legumes Sensory Evaluation Food Technology

Energetic-protein supplementation in the last 60 days of gestation improves performance of beef cows grazing tropical pastures

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Journal of Animal Science and Biotechnology 2018年第1期9卷 208-216页

作者： Aline Gomes da Silva Mário fonseca Paulino Edenio detmann Henrique Jorge Fernandes Lincoln da Silva Amorim Román Enrique Maza Ortega Victor Valério de Carvalho Josilaine Aparecida da Costa lima Felipe Henrique de Moura Mariana Benevides Monteiro Jéssika Almeida Bitencourt Universidade Federal de Vicosa VicosaMinas Gerais 36570-000Brazil Universidade Federal de Mato Grosso do Sul Campo GrandeMato Grosso do Sul 79074-460Brazil Universidade Estadual de Mato Grosso do Sul AquidauanaMato Grosso do Sul 79200-000Brazil Biotran Biotecnologia e Treinamento em Reproducao Animal AlfenasMinas Gerais 37130-000Brazil Universidade Federal do Acre Rio BrancoAcre 69920-900Brazil

Background： Nutrition is one of the most important factors that affect animal performance, and it therefore also impacts on financial results in beef systems. In this way, finding the best strategy for feeding supplements is of paramount importance. Aiming to evaluate the effect of supplement feeding strategies for beef cows in the last third of gestation, two experiments were conducted. In Experiment 1, 35 pregnant Nellore cows were assigned to a completely randomized design with four treatments： control, which received no supplement; supplementation for the last 30 d of gestation（30-d; 3.0 kg/d）; supplementation for the last 60 d of gestation（60-d; 1.5 kg/d）; or supplementation for the last 90 d of gestation（90-d; 1.0 kg/d）. All supplemented treatments received the same total amount of supplement throughout the experiment： 90 kg（20% of crude protein）. A second experiment（Experiment 2） was delineated to evaluate the effects of the amounts offered in Experiment 1 on intake and metabolism. Four multiparous pregnant Nellore cows were assigned to a 4 × 4 Latin square design, with periods of15 d ***： There was a linear effect of the number of days of supplementation on calving body weight（BW; P 〈 0.05）and a quadratic effect on BW change from parturition to d 31 post-calving（P 〈 0.05）, with cows on the 60-d strategy losing less BW post-calving. No difference was found in offspring birth BW（P 〉 0.10）. A significant linear effect on interval from parturition to conception（P 〈 0.05） was observed, with the highest calving to conception interval being observed in the 90-d strategy. The level of supplementation did not affect forage intake or neutral detergent fiber digestibility（P 〉 0.10）. Nitrogen excreted through urine tended to increase linearly with the level of supplementation（P 〈 0.10）.Conclusion： Providing 1.5 kg of supplement during the last 60 d of gestation improves cow performance after calving, reducing the magnitude of BW lost, and reduces the number of

关键词： Flushing Nutrition Parturition Reproduction

Concordance of the point-of-care circulating cathodic antigen test for the diagnosis of intestinal schistosomiasis in a low endemicity area

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Infectious Diseases of Poverty 2019年第3期8卷 99-100页

作者： Sergei Rodrigo Magalhaes de Sousa Isabelle Helena lima Dias Alvaro Luan Santana fonseca Bianca Rodrigues Contente Joyce Favacho Cardoso Nogueira Tatyellen Natasha da Costa Oliveira Stefan Michael Geiger Martin Johannes Enk Programa de Pos-Graduacao Strictu Sensu em Biologia Parasitaria na Amazonia da Universidade do Estado do Para Tv.Perebebui2623-MarcoBelemPA 66087Brazil Laboratorio de Parasitoses Intestinais Esquistossomose e Malacologia(LPIEM)Secgao de ParasitologiaInstituto Evandro Chagas/SVS/MSAnanindeuaParaBrazil

Background:The Kato-Katz technique is recommended worldwide for the diagnosis of intestinal schistosomiasis,detecting parasite eggs in feces of infected ***,new tests have been developed in order to facilitate diagnosis,*** detection of specific antigens secreted by schistosomes,such as the circulating cathodic antigen(CCA).The aim of this study was to evaluate the performance of the point-of-care circulating cathodic antigen test(POC-CCA)compared to the Kato-Katz technique in a low prevalence area in the Amazon Region,located in the municipality of Primavera,State of Para,***:Positivity rates of the POC-CCA test and the Kato-Katz technique were *** sensitivity,specificity,accuracy and kappa coefficient were determined by comparing both *** reference standard was established using 16 Kato-Katz slides,12 of the first fecal sample,two of the second and two of the third *** study also included the concordance between POC-CCA results and different numbers and combinations of Kato-Katz ***:The prevalence of schistosomiasis according to the reference standard or POC-CCA test reached a rate of 9.4%or 23.9%,respectively,among a total of 372 *** positivity rates by the Kato-Katz technique increased from 2.4 to 9.4%,according to the increase in the number of slides examined and fecal samples colleaed.A sensitivity of 55.6%,specificity 76.9%,accuracy 76%and k coefficient of 0.06 was observed by comparing one slide of the first sample and *** 6 slides from three different samples,two slides of each,with POC-CCA resulted in a sensitivity of 583%,specificity 78.4%,accuracy 77%and k coefficient of ***,the comparison of 16 slides from three different samples with POC-CCA revealed a sensitivity of 65.7%,specificity 80.4%,accuracy 79%,and k coefficient of ***:The immunochromatographic test has the potential to be an important tool to combat schistosomiasis because of its practi

关键词： Schistosoma mansoni Kato-Katz POC-CCA Accuracy Diagnosis Low prevalence area

Bipolar and Schizophrenia Disorders Diagnosis Using Artificial Neural Network

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Neuroscience & Medicine 2018年第4期9卷 209-220页

作者： Mateus Beck fonseca Renan Soares de Andrades Suelen de lima Bach Carolina David Wiener Jean Pierre Oses Engineer Center Federal University of Pelotas Pelotas Brazil department of Health and Behavior Clinical Neuroscience Lab Catholic University of Pelotas Pelotas Brazil Anhanguera Educacional Rio Grande Brazil department of Electronic Engineering and Computer Catholic University of Pelotas Pelotas Brazil

Motivation: Bipolar disorder (BD) and schizophrenia (SZ) has a difficult diagnosis, so the main objective of this article is to propose the use of Artificial Neural Networks (ANNs) to classify (diagnose) groups of patients with BD or SZ from a control group using sociodemographic and biochemical variables. Methods: Artificial neural networks are used as classifying tool. The data from this study were obtained from the array collection from Stanley Neuropathology Consortium databank. Inflammatory markers and characteristics of the sampled population were the inputs variables. Results: Our findings suggest that an artificial neural network could be trained with more than 90% accuracy, aiming the classification and diagnosis of bipolar, schizophrenia and control healthy group. Conclusion: Trained ANNs could be used to improve diagnosis in Schizophrenia and Bipolar disorders.

关键词： Bipolar Disorder Schizophrenia Disorder Biomarkers Artificial Neural Network