检索结果-南通市图书馆

Platelet-rich plasma application in diabetic ulcers:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Dermatology 2022年第1期10卷 1-9页

作者： Victoria Pereira Simão Carolina souza Cury Gabriel Mota Zamariolli Tavares Gabriel Calixto Ortega Arthur Cichetto Ribeiro Gabriel Silva santos JoséFábio santos Duarte Lana Medical School Centro Universitário LusíadaSantos 11045-101São PauloBrazil Biomedical Science Brazilian Institute of Regenerative MedicineIndaiatuba 13334-170São PauloBrazil Department ofOrthopedics Brazilian Institute of Regenerative MedicineIndaiatuba 13334-170São PauloBrazil

There are 422 million diabetic people in the world.25%of these individuals are diagnosed with diabetic foot ulcer(DFU).20%of patients with DFU will suffer amputation of the lower *** amputation procedures,the mortality rate of patients is over 70%in 5 *** has no cure and,therefore,treatment aims to prevent and treat its *** platelet-rich plasma(PRP)has been shown to be a therapeutic tool for many types of disorders,including the treatment of *** manuscript aims to carry out a review to provide more knowledge about the efficacy and safety of autologous PRP for wound closure in patients with *** majority of studies included in this review state that PRP promotes improvement of DFU lesions by accelerating tissue healing ***,many studies have a small sample size and thus require larger sample range in order to improve robustness of data in the literature.

关键词： Diabetic foot ulcer Platelet-rich plasma Wound healing Tissue regeneration Inflammation

Metal Transport Parameters in Residual Soil with an Undisturbed and Remolded Structure Percolated by an Acid Solution

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Protection 2011年第8期2卷 1076-1083页

作者： Eduardo Pavan Korf Antonio Thomé Nilo Cesar Consoli Rafael de souza Tímbola Gláucia Carine dos santos 不详

There is no enough information about metal transport parameters in residual soil. These soils are generally structured and still there is no answer to what happens with the contaminant transport parameters when an acid solution with metal percolates this material with different structure. The objective of this study was to determine the contaminant transport parameters for Cd, Ni, Cu and Zn metals in an acid multispecies solution to a residual soil from south Brazil with an undisturbed and remolded structure. Column tests were carried out to determine the kd, Rd, Dh transport parameters. It was possible conclude that the magnitude of the kd, Rd and Dh parameter did not vary significantly with the soil structure.

关键词： Pollutant Transport Column Equipment Natural Attenuation Dissolved Metals Analytical Simulation

Avocado and Cardiovascular Health

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Endocrine and Metabolic Diseases 2015年第7期5卷 77-83页

作者： Camila Weschenfelder Júlia Lorenzon dos santos Priscilla Azambuja Lopes de souza Viviane Paiva de Campos Aline Marcadenti Postgraduate Studies Program in Cardiology Instituto de Cardiologia/Fundacao Universitária de Cardiologia do Rio Grande do Sul (IC/FUC) Porto Alegre Brazil Department of Nutrition Federal University of Health Sciences of Porto Alegre (UFCSPA) Porto Alegre Brazil

Avocado is a fruit which had a caloric density of 1.7 kcal per gram and a half unit (~70 g) is composed by 114 kcal, 4.6 g of fibers, 345 mg of potassium, 19.5 mg of magnesium, 1.3 mg of vitamin E and 57 mg of phytosterols. Approximately 75% of fiber’s avocado contents are considered insoluble and 25% are soluble. The avocado contains lipids that consist of 71% from monounsaturated fatty acids (MUFA), 13% from polyunsaturated (PUFA) and 16% from saturated fatty acids (SFA). Recent researches have shown that avocado may improve hypercholesterolemia and may be useful in the treatment of hypertension and type 2 diabetes mellitus (T2DM). This way, avocado plays an important role in the cardiovascular health. This review summarizes the potential benefits of avocado consumption in the prevention of cardiovascular risk factors and metabolic diseases.

关键词： Persea Diabetes Mellitus Type 2 Dyslipidemias Nutritional Status Blood Pressure

Graves' Disease Thyroid Color-Flow Doppler Ultrasonography Assessment: Review Article

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Health 2014年第12期6卷 1487-1496页

作者： Thiago Adler Ralho Rodrigues dos santos Rodrigo Otavio Gomes Pina Marina Taliberti Pereira de souza Maria Cristina Chammas Service of Ultrasound Department of Radiology Hospital das Clinicas da Faculdade de Medicina da Universidade de S&atilde o Paulo S&atilde o Paulo Brazil

Graves’ disease, as known today, is an autoimmune, diffuse, chronic disease of thyroid gland, as described by Robert Graves in 1835. It presents genetic predisposition and unknown etiology evidence, which is influenced in its development by several factors, including environment (dietary iodine intake, stress, drugs and infections). The disease is characterized by one or more changes: hyperthyroidism, goiter, ophthalmopathy, skin changes and pretibial myxedema, around 5% less common, and other symptoms 90% to 95%. One of the most relevant clinical practice aspects in Graves’ disease patients management is to distinguish Graves’ disease in initial phase, from other types of destructive thyrotoxicosis, in addition to evaluate therapeutic methods and efficient follow up, as well as predict early recurrence or remission of disease. Scintigraphy with pertechnetate (99 mTc) and TSH levels dosage are considered the choice for this purpose. However, they present some technical difficulties, as they are not widely available and have contraindications. In this scenario, thyroid color-flow doppler ultrasonography (US Doppler) presents a viable alternative, as a widely available, low cost, non-invasive and radiation free method, providing initial diagnosis and patients with Graves’ disease follow up. In adittion, this method is used in differential diagnosis with other causes of thyrotoxicosis in the early stage.

关键词： Thyroid Graves’ Disease Ultrasonography Color-Flow Doppler

Inhibitory Effect of the Essential Oil from Hyptis suaveolens （L.） Poit on the Growth and Aflatoxins Synthesis of Aspergillus flavus

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Life Sciences 2013年第3期7卷 276-281页

作者： Ana Carolina Pessoa Moreira Egberto santos Carmo Paulo Alves Wanderley Evandro Leite de souza Edeltrudes de Oliveira Lima Department of Pharmaceutical Sciences Federal University of Paraiba Joao Pessoa 58051-900 Brazil Academic Unit of Health Federal University of Campina Grande Cuitd 58175-000 Brazil Department of Agriculture Federal University of Paraiba Bananeiras 58220-000 Brazil Laboratory of Food Microbiology Department of Nutrition Federal University of Paraiba Joao Pessoa 58051-900 Brazil

H. suaveolens （L.） Poit has been used in folk medicine revealing a wide pharmacological potential. This study aimed to evaluate the efficacy of the essential oil from 11. suaveolens leaves in inhibiting the growth of A. flavus LM257 and synthesis of aflatoxins Bl and B2. The essential oil at 20, 40 and 80 laL/mL strongly reduced the biomass and spore germination ofA. flavus. A 100% inhibition was found at 40 μL/mL and 80μL/mL, while at 20 μL/mL the growth depressed over 50% for both tested parameters. The essential oil at all assayed concentrations totally inhibited the production of aflatoxin B1 and B2. From these results, the essential oil from 11. suaveolens leaves may be considered as an alternative and effective inhibitor ofA. flavus, in addition to offer some protective effect to the production of aflatoxins.

关键词： Hyptis suaveolens essential oil Aspergillusflavus mycotoxins inhibitory effect.

Using Social Networks to Support Software Ecosystems Comprehension and Evolution

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Social Networking 2014年第2期3卷 108-118页

作者： Rodrigo Pereira dos santos Maria Gilda P. Esteves Gleisson de S. Freitas Jano Moreira de souza System Engineering and Computer Science COPPE University of Rio de Janeiro Rio de Janeiro Brazil

The software industry has evolved to a multiple-product development created on a platform and based on a common architecture integrated to other systems. This integration happens through components and third-party developers networks in Software Ecosystems (SECOs). Since systems and software development processes present challenges beyond the technical side, SECOs have emerged as an approach to improve the Software Engineering (SE) mindset in the industry. This fact changes the software industry as it requires the management of an integrated social-based environment to support a transition from an intra-organizational to an open business model approach towards a SECO approach. In this context, social networks can be important to coordinate a collaborative and distributed environment to develop SECOs platforms. This paper analyses the impact of social networks in SECOs through an integrated framework of the SECO and social network challenges. So, a proposal for a sociotechnical-based architecture to support the SECOs lifecycle is discussed.

关键词： Software Ecosystems Social Networks Software Life Cycle Innovation

From Helicobacter pylori infection to gastric cancer:Current evidence on the immune response

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2022年第3期13卷 186-199页

作者： Vinícius Lima de souza Gonçalves Maria Luísa Cordeiro santos Marcel Silva Luz Hanna santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Cláudio Lima souza Márcio Vasconcelos Oliveira Fabrício Freire de Melo Universidade Estadual do Sudoeste da Bahia Campus Vitória da ConquistaVitória da Conquista 45083-900BahiaBrazil Universidade Federal da Bahia Instituto Multidisciplinar em SaúdeVitória da Conquista 45029-094BahiaBrazil

Gastric cancer(GC)is the result of a multifactorial process whose main components are infection by Helicobacter pylori(***),bacterial virulence factors,host immune response and environmental *** development of the neoplastic microenvironment also depends on genetic and epigenetic changes in oncogenes and tumor suppressor genes,which results in deregulation of cell signaling pathways and apoptosis *** review summarizes the main aspects of the pathogenesis of GC and the immune response involved in chronic inflammation generated by ***.

关键词： Gastric cancer Helicobacter pylori Chronic inflammation Host immune response

Chlamydoconidium-producing Trichophyton tonsurans: Atypical morphological features of strains causing tinea capitis in Ceará, Brazil

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2019年第8期12卷 380-384页

作者： Raimunda Samia Nogueira Brilhante Germana Costa Paixao Jonathas Sales de Oliveira Vandbergue santos Pereira Marcos Fábio Gadelha Rocha Reginaldo Goncalves de Lima-Neto Débora de souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro JoséJúlio Costa Sidrim Specialized Medical Mycology Center Postgraduate Program in Medical MicrobiologyFederal University of CearáRua Nunes de Melo1315FortalezaBrazil Postgraduate Program in Veterinary Sciences State University of CearáAv.Dr.Silas Munguba1700FortalezaBrazil Department of Tropical Medicine Center for Health SciencesFederal University of PernambucoRecife-PEBrazil

Objective: To report atypical morphological features of Trichophyton(T.) tonsurans strains associated with tinea capitis. Methods: Eighty-two T. tonsurans strains isolated in Ceará, Brazil, were analyzed regarding macro and micromorphological features and nutritional patterns. Results: Fifty-two samples presented abundant chlamydoconidia, which were produced in chains. Macroscopically, these strains developed small glabrous colonies that were firmly attached to the surface of the culture medium, with few or no aerial mycelia and intense rusty yellow pigmentation. Seven strains did not grow with stimulus from thiamine. Samples were heterogeneous regarding urease production and none presented in vitro hair perforation. Conclusions: The observation of T. tonsurans strains with distinct phenotypic features indicates the need to revise the taxonomic criteria for routine identification of this dermatophyte.

关键词： Trichophyton tonsurans Chlamydoconidia Dermatophyte Phenotyping

Characterization of goat whey proteins and their bioactivity and toxicity assay

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Bioscience 2022年第2期46卷 833-843页

作者： Maria Isabel Ferreira Campos Paula Perazzo de souza Barbosa Laura Junqueira Camargo Luciano Da Silva Pinto Bianca Mataribu Catarina Serr˜ao Luis Fernando Marques-santos Jos´e Hon´orio Lopes Julia Mariano Caju de Oliveira Carlos Alberto de Almeida Gadelha Tatiane Santi-Gadelha Programa de P´os-Graduaç˜ao em Ciˆencia e Tecnologia de Alimentos Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil Departamento de Biologia Molecular Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil Centro de Desenvolvimento Tecnol´ogico Universidade Federal de PelotasRio Grande do SulBrazil Programa de P´os-Graduaç˜ao em Ciˆencias da Nutriç˜ao Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil

Goat whey is an industry-discarded dairy by-product that has interesting nutritional value and a nutrient composition with important functional potential,where proteins have a high biological value and play an important role in the organism’s ***,the aim of this study was to identify,quantify,concentrate and investigate the capacity of goat whey proteins to perform different biological activities and to evaluate their acute *** proteins were quantified and identified by Bradford,Kjehdal and SDS-PAGE *** activity was performed against Listeria monocytogenes,Salmonella spp.,Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli microorganisms and showed MIC ranging from 15 to 120μg mL-1,with the highest inhibition for *** *** activity was performed against human malignant melanoma cells and their proliferation inhibition was up to 66.8%within 72 h of *** highest antioxidant capacity was obtained at concentration 2 mg that showed 29.69%of inhibition of DPPH radical *** acute toxicity test was performed using Artemia franciscana larvae in which whey proteins were able to preserve larval survival throughout ***,we can conclude that goat’s whey has proteins that can play a positive effect on health,with antimicrobial activity and without *** present study highlights the great potential of goat’s whey to be developed as a safe biopreservative or as a functional ingredient in the food industry.

关键词： Goat whey proteins Malignant cells Antimicrobial Antioxidant capacity Whey protein functionality