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Variation in Heat-shock Proteins and Photosynthetic Thermotolerance among Natural Populations of Chenopodium album *** Contrasting Thermal Environments:Implications for Plant Responses to Global Warming

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Journal of Integrative Plant Biology 2008年第11期50卷 1440-1451页

作者： deepak Barua Scott A.Heckathorn James S.Coleman Department of Biology Syracuse University Department of Organismic and Evolutionary Biology Harvard University Department of Environmental Sciences University of Toledo

Production of heat-shock proteins （Hsps） is a key adaptation to acute heat stress and will be important in determining plant responses to climate change. Further, intraspecifc variation in Hsps, which will influence species-level response to global warming, has rarely been examined in naturally occurring plants. To understand intraspecific variation in plant Hsps and its relevance to global warming, we examined Hsp content and thermotolerance in five naturally occurring populations of Chenopodium album L. from contrasting thermal environments grown at low and high temperatures. As expected, Hsp accumulation varied between populations, but this was related more to habitat variability than to mean temperature. Unexpectedly, Hsp accumulation decreased with increasing variability of habitat temperatures. Hsp accumulation also decreased with increased experimental growth temperatures. Physiological thermotolerance was partitioned into basal and induced components. As with Hsps, induced thermotolerance decreased with increasing temperature variability. Thus, populations native to the more stressful habitats, or grown at higher temperatures, had lower Hsp levels and induced thermotolerance, suggesting a greater reliance on basal mechanisms for thermotolerance. These results suggest that future global climate change will differentially impact ecotypes within species, possibly by selecting for increased basal versus inducible thermotolerance.

关键词： acclimation photosynthesis stress proteins temperature.

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Nutrition in acute pancreatitis

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World Journal of Gastrointestinal Surgery 2023年第4期15卷 534-543页

作者： Srikanth Gopi Anoop Saraya deepak Gunjan Gastroenterology and Human Nutrition Unit All India Institute of Medical SciencesNew Delhi 110029India

Acute pancreatitis(AP)has varying severity,and moderately severe and severe AP has prolonged hospitalization and requires multiple *** patients are at risk of *** is no proven pharmacotherapy for AP,however,apart from fluid resuscitation,analgesics,and organ support,nutrition plays an important role in the management of *** or enteral nutrition(EN)is the preferred route of nutrition in AP,however,in a subset of patients,parenteral nutrition is *** has various physiological benefits and decreases the risk of infection,intervention,and *** is no proven role of probiotics,glutamine supplementation,antioxidants,and pancreatic enzyme replacement therapy in patients with AP.

关键词： Acute pancreatitis Enteral Parenteral Nutrition Malnutrition

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Vascular complications of chronic pancreatitis and its management

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World Journal of Gastrointestinal Surgery 2023年第8期15卷 1574-1590页

作者： Dinesh Walia Anoop Saraya deepak Gunjan Gastroenterology and Human Nutrition Unit All India Institute of Medical SciencesNew Delhi 110029India

Chronic pancreatitis is a chronic fibro-inflammatory disorder of the pancreas,resulting in recurrent abdominal pain,diabetes mellitus,and *** may lead to various other complications such as pseudocyst formation,benign biliary stricture,gastric outlet obstruction;and vascular complications like venous thrombosis,variceal and pseudoaneurysmal *** of varices is usually due to chronic venous thrombosis with collateral formation and variceal bleeding can easily be tackled by endoscopic *** bleed can be catastrophic and requires radiological interventions including digital subtraction angiography followed by endovascular obliteration,or sometimes with a percutaneous or an endoscopic ultrasound-guided approach in technically difficult ***-related bleed is usually venous and mostly managed ***-related arterial bleed,however,may require radiological interventions.

关键词： Chronic pancreatitis Pseudoaneurysm Vascular complications Varices Venous thrombosis

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What,why and how to monitor blood glucose in critically ill patients

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World Journal of Diabetes 2023年第5期14卷 528-538页

作者： Deven Juneja Desh deepak Prashant Nasa Institute of Critical Care Medicine Max Super Speciality HospitalSaketNew Delhi 110017India Department of Critical Care King's College HospitalDubai 340901United Arab Emirates Department of Critical Care NMC Speciality HospitalDubai 7832United Arab Emirates Department of Critical Care College of Medicine and Health SciencesAl Ain 15551United Arab Emirates

Critically ill patients are prone to high glycemic variations irrespective of their diabetes *** mandates frequent blood glucose(BG)monitoring and regulation of insulin *** though the most commonly employed capillary BG monitoring is convenient and rapid,it is inaccurate and prone to high bias,overestimating BG levels in critically ill *** targets for BG levels have also varied in the past few years ranging from tight glucose control to a more liberal *** of these has its own fallacies,while tight control increases risk of hypoglycemia,liberal BG targets make the patients prone to ***,the recent evidence suggests that BG indices,such as glycemic variability and time in target range,may also affect patient *** this review,we highlight the nuances associated with BG monitoring,including the various indices required to be monitored,BG targets and recent advances in BG monitoring in critically ill patients.

关键词： Blood glucose Continuous glucose monitoring Critical care Glycaemic indices Hypoglycaemia Intensive care unit

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Synthesis of amorphous manganese borohydride in the(NaBH_4–MnCl_2) system, its hydrogen generation properties and crystalline transformation during solvent extraction

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Journal of Energy Chemistry 2017年第1期26卷 24-34页

作者： Robert A.Varin deepak K.Mattar Amirreza Shirani Bidabadi Marek Polanski Department of Mechanical and Mechatronics Engineering and Waterloo Institute for Nanotechnology University of Waterloo Faculty of New Technologies and Chemistry Military University of Technology

The mixture of(2NaBH4+ MnCl2) was ball milled in a magneto-mill. No gas release was detected. The XRD patterns of the ball milled mixture exhibit only the Bragg diffraction peaks of the Na Cl-type salt which on the basis of the present X-ray diffraction results and the literature is likely to be a solid solution Na(Cl)x(BH4)(1-x), possessing a cubic Na Cl-type crystalline structure. No presence of any crystalline hydride was detected by powder X-ray diffraction which clearly shows that NaBH4in the initial mixture must have reacted with MnCl2forming a Na Cl-type by-product and another hydride that does not exhibit X-ray Bragg diffraction peaks. Mass spectrometry(MS) of gas released from the ball milled mixture during combined MS/thermogravimetric analysis(TGA)/differential scanning calorimetry(DSC) experiments, confirms mainly hydrogen(H2) with a small quantity of diborane gas, B2H6. The Fourier transform infra-red(FT-IR) spectrum of the ball milled(2NaBH4+ MnCl2) is quite similar to the FT-IR spectrum of crystalline manganese borohydride, c-Mn(BH4)2, synthesized by ball milling, which strongly suggests that the amorphous hydride mechano-chemically synthesized during ball milling could be an amorphous manganese borohydride. Remarkably, the process of solvent filtration and extraction at 42 °C, resulted in the transformation of mechano-chemically synthesized amorphous manganese borohydride to a nanostructured,crystalline, c-Mn(BH4)2hydride.

关键词： Ball milling Mechano-chemical activation synthesis Amorphous manganese borohydride Mn(BH4)2 Dehydrogenation behavior Solvent extraction Crystallization of manganese borohydride Mn(BH4)2

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Intelligent optimization of renewable resource mixes incorporating the effect of fuel risk, fuel cost and CO2 emission

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Frontiers in Energy 2015年第1期9卷 91-105页

作者： deepak KUMAR D. K. MOHANTA M. Jaya Bharata REDDY School of Electrical Sciences Indian Institute of Technology Bhuba-neswar Odisha 751013 India Electrical Engineering Department Birla Institute of Technology MesraRanchi 835215 India Electrical Engineering Department National Institute of TechnologyTrichy 620015 India

Power system planning is a capital intensive investment-decision problem. The majority of the conven- tional planning conducted since the last half a century has been based on the least cost approach, keeping in view the optimization of cost and reliability of power supply. Recently, renewable energy sources have found a niche in power system planning owing to concerns arising from fast depletion of fossil fuels, fuel price volatility as well as global climatic changes. Thus, power system planning is under-going a paradigm shift to incorporate such recent technologies. This paper assesses the impact of renewable sources using the portfolio theory to incorporate the effects of fuel price volatility as well as CO2 emissions. An optimization framework using a robust multi-objective evolutionary algorithm, namely NSGA-II, is developed to obtain Pareto optimal solutions. The performance of the proposed approach is assessed and illustrated using the Indian power system considering real-time design prac- tices. The case study for Indian power system validates the efficacy of the proposed methodology as developing countries are also increasing the investment in green energy to increase awareness about clean energy technologies.

关键词： modem portfolio theory energy policy CO2 emissions multi-objective optimization planning commis-sion

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Effect of Oxygen Admittance Temperature on the Growth of ZnO Microcrystals by Thermal Evaporation Technique

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Journal of Materials Science & Technology 2012年第4期28卷 317-320页

作者： K.M.K. Srivatsa deepak Chhikara M. Senthil Kumar Physics of Energy Harvesting Division National Physical Laboratory Council of Scientific & Industrial Research (CSIR) New Delhi 110012 India

Hexagonally well-faceted microcrystals of ZnO have been grown by thermal evaporation of Zn powder in oxygen ambient at 700℃ under atmospheric pressure. It has been observed that the properties （size and quality） of ZnO microcrystals have a strong dependence on the reactor temperature at which the oxygen gas is admitted into the growth zone. The microcrystals grown with oxygen admittance at 450℃ have a length of 1 μm and a diameter of 0.75 μm while that grown with oxygen admittance at 600 ℃ have a length of 1.5-2 μm and a diameter of 1 μm. Room temperature photoluminescence spectra show a ultraviolet （UV） emission peak at 385 nm with a green band emission at around 500 nm. The UV-to-green band emission ratio for the microcrystals grown with oxygen admittance at 450℃ is observed to be 1.25 and the ratio decreases to 0.45 for the sample grown with oxygen admittance at 600℃.

关键词： ZnO microcrystals Thermal evaporation Scanning electron microscopy Transmission electron microscopy Room temperature photoluminescence

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Linking stemness with colorectal cancer initiation, progression, and therapy

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World Journal of Stem Cells 2019年第8期11卷 519-534页

作者： deepak Narayanan Iyer Wai-Yan Sin Lui Ng Department of Surgery Li Ka Shing Faculty of Medicine The University of Hong Kong

The discovery of cancer stem cells caused a paradigm shift in the concepts of origin and development of colorectal cancer. Several unresolved questions remain in this field though. Are colorectal cancer stem cells the cause or an effect of the disease? How do cancer stem cells assist in colorectal tumor dissemination to distant organs? What are the molecular or environmental factors affecting the roles of these cells in colorectal cancer? Through this review, we investigate the key findings until now and attempt to elucidate the origins, physical properties, microenvironmental niches, as well as the molecular signaling network that support the existence, self-renewal, plasticity, quiescence, and the overall maintenance of cancer stem cells in colorectal cancer. Increasing data show that the cancer stem cells play a crucial role not only in the establishment of the primary colorectal tumor but also in the distant spread of the disease. Hence, we will also look at the mechanisms adopted by cancer stem cells to influence the development of metastasis and evade therapeutic targeting and its role in the overall disease prognosis. Finally, we will illustrate the importance of understanding the biology of these cells to develop improved clinical strategies to tackle colorectal cancer.

关键词： Cancer stem cell Colorectal cancer Tumor microenvironment Metastasis Extracellular matrix Tumor heterogeneity Resistance Stemness Quiescence Recurrence

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Synthesis of Anatase Titania Nanostructures at Room Temperature by PECVD Technique

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Journal of Materials Science & Technology 2011年第8期27卷 696-700页

作者： K.M.K. Srivatsa deepak Chhikara M. Senthil Kumar Materials Physics and Engineering Division National Physical Laboratory Council of Scientific & Industrial Research (CSIR) Physics of Energy Harvesting Division National Physical Laboratory Council of Scientific & Industrial Research (CSIR)

titania nanostructures have been synthesized at room temperature by plasma enhanced chemical vapor deposition （PECVD） process on silicon （100） substrates using titanium tetraisopropoxide [Ti（OC3H7）4, TTIP] vapor, argon and oxygen mixtures under various deposition pressures. The deposited titania has been characterized for its structural, morphological and chemical composition by X-ray diffraction, scanning electron microscopy, energy dispersive X-ray （EDX） spectroscopy and Fourier transform infrared （FTIR） spectroscopy recordings. With the variation of deposition pressure, titania assumes various nanostructures viz. nanocrystals, nanoparticles, noanorods and comb-like structure. EDX and FTIR measurements show that the deposited titania is of high chemical purity. The possible growth mechanisms for the observed titania nanostructures have been discussed.

关键词： Nanostructures Plasma enhanced chemical vapor deposition Anatase titania

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Near-saturated soil hydraulic conductivity and pore characteristics as influenced by conventional and conservation tillage practices in North-West Himalayan region,India

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International Soil and Water Conservation Research 2021年第2期9卷 249-259页

作者： deepak Singh Alok Kumar Mishra Sridhar Patra Sankar Mariappan Nisha Singh ICAR-Indian Institute of Soil and Water Conservation Dehradun248195UttarakhandIndia Sam Higginbottom University of Agriculture Technology and SciencesPrayagraj211007U.PIndia Hemvati Nandan Bahuguna Garhwal University(A Central University) Srinagar(Garhwal)246174UttarakhandIndia

Tillage plays an important role in modifying soil hydraulic *** objective of the present study was to evaluate the effect of conservation tillage practices in a maize-wheat cropping system on nearsaturated soil hydraulic properties and pore characteristics in the North-West Himalayan region,*** treatments *** tillage(CT),minimum tillage(MT),and zero tillage(ZT)were evaluated in terms of field saturated hydraulic conductivity(ks),unsaturated hydraulic conductivity k(h),the inverse of capillary length(a),flow-weighted mean pore radius(r0),numbers of pores per square meter(n0)and water-conducting macroporosity(Ɛ).The above hydraulic conductivity and pore characteristics were derived from steady-state water flux(q)measured using hood infiltrometer at 0,1,and3 cm pressure head for each treatment after seven years of establishment of this tillage *** revealed significantly(p0.50 mm conducted about 63.60,68.01,and 75.97%of total flow(at 0 cm pressure head)in the corresponding water-conducting macroporosity of 0.00030,0.00044,and 0.00069%of soil volume under CT,MT,and ZT,***,zero-tillage based agriculture system was found to improve near-saturated soil hydraulic properties.

关键词： Near-saturated hydraulic conductivity Macropores Tillage Flow weighted mean pore radius Water-conducting macroporosity

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