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Mapping the global research landscape on nutrition and the gut microbiota:Visualization and bibliometric analysis

World Journal of Gastroenterology 2022年第25期28卷 2981-2993页

作者： Sa'ed H Zyoud Muna Shakhshir Amani S abushanab Samah W Al-Jabi Amer Koni Moyad Shahwan Ammar Abdulrahman Jairoun adham abu taha Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Information Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Division of Clinical Pharmacy Hematology and Oncology Pharmacy DepartmentAn-Najah National University HospitalNablus 44839Palestine Department of Pharmacy Ajman UniversityAjman 346United Arab Emirates Centre of Medical and Bio-allied Health Sciences Research Ajman UniversityAjman 346United Arab Emirates Department of Health and Safety Dubai MunicipalityDubai 67United Arab Emirates Department of Biomedical Sciences College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine

BACKGROUND Nutrition is a significant modifiable element that influences the composition of the gastrointestinal microbiota,implying the possibility of therapeutic diet methods that manipulate the composition and diversity of the *** To overview research papers on nutrition and gut microbiota and determines the hotspots in this field at the global *** Scopus and Reference Citation Analysis were used to construct a bibliometric *** was decided to create bibliometric indicators and mapping as in most previous studies.2012 through 2021 served as the study's *** A total of 5378 documents from the Scopus database were selected for *** all retrieved studies,78.52%were research papers(n=4223),followed by reviews(n=820;15.25%).China ranked first with a total number of articles of 1634(30.38%),followed by the United States in second place with a total number of articles of 1307(24.3%).In the last decade,emerging hotspots for gut microbiota and nutrition research included"gut microbiota metabolism and interaction with dietary components","connection between the gut microbiota and weight gain",and"the influence of high-fat diet and gut microbiota on metabolic disorders".CONCLUSION This is the first thorough bibliometric analysis of nutrition and gut microbiota publications conducted on a global *** of the association between nutrition/diet and the gut microbiota is still in its infancy and will be expanded in the ***,according to recent trends,the"effect of gut microbiota and high-fat diet on metabolic disorders"will be an increasing concern in the future.

关键词： Gut microbiota Microbiome Nutrition Diet Bibliometric Scopus VOSviewer

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Unveiling the hidden world of gut health:Exploring cutting-edge research through visualizing randomized controlled trials on the gut microbiota

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World Journal of Clinical Cases 2023年第26期11卷 6132-6146页

作者： Sa’ed H Zyoud Muna Shakhshir Amani S abushanab Amer Koni Moyad Shahwan Ammar Abdulrahman Jairoun adham abu taha Samah W Al-Jabi Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Division of Clinical Pharmacy Hematology and Oncology Pharmacy DepartmentAn-Najah National University HospitalNablus 44839Palestine College of Pharmacy and Health Sciences Ajman UniversityAjman 346United Arab Emirates Department of Health and Safety Dubai MunicipalityDubai 67United Arab Emirates Discipline of Clinical Pharmacy School of Pharmaceutical SciencesUniversiti Sains Malaysia(USM)Pulau Pinang 11500Malaysia Department of Pathology An-Najah National University HospitalNablus 44839Palestine

BACKGROUND The gut microbiota plays a crucial role in gastrointestinal and overall *** clinical trials(RCTs)play a crucial role in advancing our knowledge and evaluating the efficacy of therapeutic interventions targeting the gut *** To conduct a comprehensive bibliometric analysis of the literature on RCTs involving the gut *** Using bibliometric tools,a descriptive cross-sectional investigation was conducted on scholarly publications concentrated on RCTs related to gut microbiota,spanning the years 2003 to *** study used VOSviewer version 1.6.9 to examine collaboration networks between different countries and evaluate the frequently employed terms in the titles and abstracts of the retrieved *** primary objective of this analysis was to identify key research areas and focal points associated with RCTs involving the gut *** A total of 1061 relevant articles were identified from the 24758 research articles published between 2003 and *** number of publications showed a notable increase over time,with a positive correlation(R2=0.978,P<0.001).China(n=276,26.01%),the United States(n=254,23.94%),and the United Kingdom(n=97,9.14%)were the leading contributing countries.Københavns Universitet(n=38,3.58%)and Dankook University(n=35,3.30%)were the top active *** co-occurrence analysis shows current gut microbiota research trends and important topics,such as obesity interventions targeting the gut microbiota,the efficacy and safety of fecal microbiota transplantation,and the effects of dietary interventions on *** The study highlights the rapid growth and importance of research on RCTs that involve the gut *** study provides valuable insight into research trends,identifies key players,and outlines potential future directions in this ***,the co-occurrence analysis identified important topics that play a critical role in the advancement of science

关键词： Gut microbiota Microbiome Randomized clinical trials Bibliometric analysis

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Mapping the global research landscape on insulin resistance: Visualization and bibliometric analysis

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World Journal of Diabetes 2022年第9期13卷 786-798页

作者： Sa’ed H Zyoud Muna Shakhshir Amer Koni Amani S abushanab Moyad Shahwan Ammar Abdulrahman Jairoun Rand Al Subu adham abu taha Samah W Al-Jabi Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Information Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Division of Clinical Pharmacy Department of Hematology and Oncology PharmacyAn-Najah National University HospitalNablus 44839Palestine Department of Pharmacy Ajman UniversityAjman 346United Arab Emirates Centre of Medical and Bio Allied Health Sciences Research Ajman UniversityAjman 346United Arab Emirates Department of Health and Safety Dubai MunicipalityDubai 67United Arab Emirates Department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Biomedical Sciences College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Pathology An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Insulin resistance is a risk factor for metabolic syndromes and is associated with a wide variety of metabolic illnesses,including obesity,type 2 diabetes,and cardiovascular *** To investigate and map global insulin resistance *** A bibliometric methodology was applied to the literature retrieved from the Scopus database and Reference Citation Analysis(https://***)by using a validated search *** study period was limited from 2002 to *** indicators and mapping were *** A total of 26808 articles on the topic of insulin resistance were included in the Scopus *** articles included research articles(n=21918;81.76%),review articles(n=2641;9.85%),and letters(n=653;2.44%).During the study period,136 countries contributed to the research on insulin *** highest number of articles was from the United States(n=7360;27.45%),followed by China(n=3713;13.85%),Japan(n=1730,6.45%),Italy(n=1545;5.54%),and the United Kingdom(n=1484;5.54%).The retrieved articles identified two main research themes:“inflammatory mechanisms in the regulation of insulin resistance”and“mechanisms linking obesity to insulin resistance”.CONCLUSION Our data show that insulin resistance has steadily gained interest from researchers,as evidenced by the number of citations and yearly *** have grown significantly in the last decade,while low-income countries with greater burdens continue to produce fewer publications in this *** approach might assist researchers in choosing new research areas and recognizing research hotspots and *** the future,perhaps high-quality clinical evidence will be acquired.

关键词： Insulin resistance Research hotspots Scopus VOSviewer Bibliometric

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Current global research landscape on COVID-19 and cancer: Bibliometric and visualization analysis

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World Journal of Clinical Oncology 2022年第10期13卷 835-847页

作者： Sa'ed H Zyoud Amer Koni Samah W Al-Jabi Riad Amer Muna Shakhshir Rand Al Subu Husam Salameh Razan Odeh Sultan Musleh Faris abushamma adham abu taha Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine Hematology and Oncology Department An-Najah National University HospitalNablus 44839Palestine Department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of Urology An-Najah National University HospitalNablus 44839Palestine Department of Pathology An-Najah National University HospitalNablus 44839Palestine Department of Biomedical Sciences College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine

BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global *** individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and increased *** To identify research hotspots and prospects,we used bibliometrics to examine the global production of COVID-19 literature published in the field of *** Data on publication output were identified based on the Scopus database between January 1,2020,and June 21,*** study used VOSviewer to analyze collaboration networks among countries and assess the terms most often used in the titles and abstracts of retrieved publications to determine research hotspots linked to cancer and *** Impact Index Per Article for the top 10 high-cited papers collected from Reference Citation Analysis(RCA)are *** A total of 7015 publications were retrieved from the *** United States published the greatest number of articles(2025;28.87%),followed by Italy(964;13.74%),the United Kingdom(839;11.96%),and China(538;7.67%).The University of Texas MD Anderson Cancer Center(n=205,2.92%)ranked first,followed by the Memorial Sloan-Kettering Cancer Center(n=176,2.51%).The European Journal of Cancer(n=106,1.51%)ranked first,followed by the Frontiers in Oncology(n=104,1.48%),Cancers(n=102,1.45%),and Pediatric Blood and Cancer(n=95;1.35%).The hot topics were stratified into“cancer care management during the COVID-19 pandemic”;and“COVID-19 vaccines in cancer patients”.CONCLUSION This is the first bibliometric analysis to determine the present state and upcoming hot themes related to cancer and COVID-19 and vice versa using VOSviewer during the early stages of the *** emergence of hot themes related to cancer and COVID-19 may aid researchers in identifying new research areas in this field.

关键词： Bibliometric Scopus COVID-19 Cancer Coronavirus disease VOSviewer Reference Citation Analysis

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Synthesis, characterization, biological activities and luminescent properties of lanthanide complexes with [2-thiophenecarboxylic acid, 2-(2-pyridinylmethylene)hydrazide] Schiff bases ligand

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Journal of Rare Earths 2016年第10期34卷 986-993页

作者： Abdulaziz M.Ajlouni Qutaiba abu-Salem Ziyad A.taha Ahmed K.Hijazi Waleed Al Momani Department of Applied Chemical Sciences Jordan University of Science and Technology Department of Chemistry Faculty of Science Al al-Bayt University Department of Basic Medical Sciences Faculty of Medicine Yarmouk University

A Schiff base L [2-thiophenecarboxylic acid, 2-（2-pyridinylmethylene）hydrazide] with its lanthanide metal complexes was synthesized. These complexes were characterized by elemental analysis, molar conductivity measurements, spectral analysis（NMR, FT-IR, and UV-Vis）, luminescence and thermal gravimetric analysis. The Schiff base ligand was a tridentate chelate and coordinates to the central lanthanide ion with 1：2 metal：ligand ratio. The conductivity data showed a 1：1 electrolytic nature with a general formula [LnL_2（NO_3）_2]NO_3. The luminescence emission properties for Sm, Tb, and Eu complexes were observed and showed that the ligand L could absorb and transfer energy to Sm（III）, Tb（III） and Eu（III） ions. The complexes possessed a good antibacterial activity against different bacterial strains. In addition, the scavenging activity of the Ln（III） complexes on DPPH was concentration dependant and the complexes were significantly more efficient in quenching DPPH than the free Schiff base ligand.

关键词： hydrazone lanthanides complexes luminescence properties antibacterial activity rare earths

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