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Geochemistry of island arc assemblage in the Eastern Desert of Egypt and the role of Pan-African magmatism in crustal growth of the Arabian–Nubian Shield:A review

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Acta Geochimica 2024年第3期43卷 588-622页

作者： Abdel-Aal MAbdel-Karim Mohamed MHamdy adel A.Surour Geology Department Faculty of ScienceZagazig UniversityZagazig 44519Egypt Geology Department Faculty of ScienceTanta UniversityTanta 31527Egypt Department of Geological Sciences Faculty of ScienceNew Galala City 43511Egypt Geology Department Faculty of ScienceCairo UniversityGiza 12613Egypt

Neoproterozoic island arc assemblage of the Arabian–Nubian Shield(ANS)in the Eastern Desert(ED)of Egypt comprises juvenile suites of metavolcanics(MV),large amounts of meta-sedimentary rocks(MS),and voluminous metagabbros-diorites(MGD)and syn-tectonic intrusions of older granitoids(OG).We report here the updates of these four rock units in terms of classification,distribution,chemical characteristics,geodynamic evolution,metamorphism,and *** addition,we discuss these integrated data to elucidate a reasonable and reliable model for crustal evolution in the *** main features of these rock units indicate their relation to each other and the geodynamic environment dominated by early immature oceanic island arcs to primitive continental *** information of the island arc metavolcanic and plutonic rocks(gabbros,diorites,tonalites,and granodiorites)furnish evidence of the genetic *** include proximity and a coeval nature in the field;all protolith magmas are subalkaline in nature following calc-alkaline series with minor tholeiitic affinities;common geochemical signature of the arc rocks and subduction-related magmatism;their similar enrichment in LREEs;and similar major element compositions with mafic melts derived from metasomatized mantle *** volcano-sedimentary and the OG rocks underwent multiphase deformation events whereas the MGD complexes deformed *** on the magmatic,sedimentological,and metamorphic evolutions constrained by geochronological data as well as the progressive evolutionary trend from extensional to compressional regimes,a possible gradual decrease in the subducted slab dip angle is the most infl uential in any geodynamic model for arc assemblage in the ED of Egypt.

关键词： Island arc assemblage Magmatism Crustal growth Neoproterozoic Arabian–Nubian Shield Eastern Desert Egypt

n-octyl acrylate is a candidate sex pheromone component involved in courtship in parasitoid wasp Microplitis mediator

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Insect Science 2024年第4期31卷 1200-1210页

作者： Yu-Xiao Tao Shuang Shan Youssef Dewer Shan-Ning Wang adel Khashaveh Rui-Jun Li Yong-Jun Zhang State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijingChina College of Plant Protection Agricultural University of HebeiBaodingHebei ProvinceChina Bioassay Research Department Central Agricultural Pesticide LaboratorySabahia Plant Protection Research StationAgricultural Research CenterAlexandriaEgypt Beijing Key Laboratory of Environment Friendly Management on Fruit Diseases and Pests in North China Institute of Plant ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijingChina

Sex pheromones are considered to play critical roles in partner communication of most parasitic ***,the identification of sex pheromone components remains limited to a few families of parasitoid *** this study,we functionally characterized a candidate sex pheromone component in Microplitis mediator(Hymenoptera:Braconidae),a solitary parasitoid of Noctuidae *** found that the body surface extract from female wasps could significantly stimulate courtship behavior of *** chromatography-electroantennographic detection(GC-EAD)analysis revealed that a candidate semiochemical from extract triggered significant electrophysiological response of antennae of *** performing gas chromatography-mass spectrometer(GC-MS)measurement,GC-EAD active compound was identified as n-octyl acrylate,a candidate sex pheromone component in female *** electroantennogram(EAG)tests,antennae of male wasps showed significantly higher electrophysiological responses to n-octyl acrylate than those of females.Y-tube olfactometer assays indicated that male wasps significantly chose n-octyl acrylate compared with the ***,male wasps showed a remarkable preference for n-octyl acrylate in a simulated field condition behavioral trial;simultaneously,n-octyl acrylate standard could also trigger significant courtship behavior in *** propose that n-octyl acrylate,as a candidate vital sex pheromone component,could be utilized to design behavioral regulators of *** to implement the protection and utilization of natural enemies.

关键词： behavioral assay courtship behavior GC-EAD analysis Microplitis mediator sex pheromone

Fine-Tuning Cyber Security Defenses: Evaluating Supervised Machine Learning Classifiers for Windows Malware Detection

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Computers, Materials & Continua 2024年第8期80卷 2917-2939页

作者： Islam Zada Mohammed Naif Alatawi Syed Muhammad Saqlain Abdullah Alshahrani adel Alshamran Kanwal Imran Hessa Alfraihi Department of Software Engineering International Islamic UniversityIslamabad25000Pakistan Information Technology Department Faculty of Computers and Information TechnologyUniversity of TabukTabuk71491Saudi Arabia Department of Computer Science and Artificial Intelligence College of Computer Science and EngineeringUniversity of JeddahJeddah21493Saudi Arabia Department of Cybersecurity College of Computer Science and EngineeringUniversity of JeddahJeddah21493Saudi Arabia Department of Computer Science University of PeshawarPeshawar25121Pakistan Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia

Malware attacks on Windows machines pose significant cybersecurity threats,necessitating effective detection and prevention *** machine learning classifiers have emerged as promising tools for malware ***,there remains a need for comprehensive studies that compare the performance of different classifiers specifically for Windows malware *** this gap can provide valuable insights for enhancing cybersecurity *** numerous studies have explored malware detection using machine learning techniques,there is a lack of systematic comparison of supervised classifiers for Windows malware *** the relative effectiveness of these classifiers can inform the selection of optimal detection methods and improve overall security *** study aims to bridge the research gap by conducting a comparative analysis of supervised machine learning classifiers for detecting malware on Windows *** objectives include Investigating the performance of various classifiers,such as Gaussian Naïve Bayes,K Nearest Neighbors(KNN),Stochastic Gradient Descent Classifier(SGDC),and Decision Tree,in detecting Windows *** the accuracy,efficiency,and suitability of each classifier for real-world malware detection *** the strengths and limitations of different classifiers to provide insights for cybersecurity practitioners and *** recommendations for selecting the most effective classifier for Windows malware detection based on empirical *** study employs a structured methodology consisting of several phases:exploratory data analysis,data preprocessing,model training,and *** data analysis involves understanding the dataset’s characteristics and identifying preprocessing *** preprocessing includes cleaning,feature encoding,dimensionality reduction,and optimization to prepare the data for *** training utilizes various

关键词： Security and privacy challenges in the context of requirements engineering supervisedmachine learning malware detection windows systems comparative analysis Gaussian Naive Bayes K Nearest Neighbors Stochastic Gradient Descent Classifier Decision Tree

Genetic Variability and Phenotypic Correlations Study among Grain Quality Traits and Mineral Elements Concentrations in Colored and Non-Colored Rice (Oryza sativa L.)

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1733-1748页

作者： adel A.Rezk Mohamed M.El-Malky Heba I.Mohamed Hossam S.El-Beltagi Agricultural Biotechnology Department College of Agricultural and Food ScienceKing Faisal UniversityAl-Ahsa31982Saudi Arabia Plant Pathology Research Institute Agriculture Research CenterGiza12619Egypt Rice Research and Training Center Field Crop Research InstituteAgriculture Research Center33717Egypt Biological and Geological Sciences Department Faculty of EducationAin Shams UniversityCairo11511Egypt Biochemistry Department Faculty of AgricultureCairo UniversityGiza12613Egypt

Twenty-four rice genotypes were examined to assess genetic variability,heritability,and correlations for seven-grain quality traits,eight nutritional elements,and *** revealed signiﬁcant differences for the quality traits *** every trait under study,the phenotypic coefﬁcient of variation was higher than the correspon-dence genotypic coefﬁcient of *** in a broad sense varied from 29.75%for grain length to 98.31%for the elongation *** percentage recovery had a highly signiﬁcant positive correlation with milling and head rice ***,milling percentage had a highly positive correlation with head rice *** amylose percentage,all the genotypes belonged to low amylose except the Hassawi-1 variety,which had intermediate amylose *** nutrition contents of magnesium(Mg),sodium(Na),potas-sium(K),calcium(Ca),copper(Cu),manganese(Mn),zinc(Zn),iron(Fe),or protein percentage gave different variations for 24 rice genotypes under all the nutritional *** the 24 genotypes,ten rice genotypes–HighNutrient-1,HighNutrient-2,HighNutrient-9,HighNutrient-8,HighNutrient-3,Hassawi-2,HighNutrient-7,HighNutrient-6,Hassawi-1,and HighNutrient-4–had the highest heist value for all nutritional and protein con-tents,and could be used as a donor to improving new *** was a positive and signiﬁcant correlation between magnesium Mg,K,Zn and ***,K had a positive correlation with zinc Zn,Fe,and protein *** analysis was divided into two groups:theﬁrst group included all genotypes rich in nutri-ents,while the remaining genotypes with low nutritional content were included in the second group.

关键词： Amylose cluster analysis genotypes grain quality mineral nutrition rice

A review:the mechanism of plant-derived polysaccharides on osteoblasts and osteoclasts

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未来食品学报(英文) 2024年第3期4卷 183-192页

作者： Mengjie Ren adel F.Ahmed Meng Li Menghan Li Zhiruo Yan Jinmei Wang National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China Joint International Research Laboratory of Food&Medicine Resource Function Henan ProvinceKaifeng 475004China Medicinal and Aromatic Plants Researches Department Horticulture Research InstituteAgricultural Research CenterGiza 12511Egypt

Bone loss and deterioration of bone microarchitecture would increase the bone fragility and fracture risk,leading to the *** and more evidences proved that plant-derived polysaccharides could have a remarkable influence on osteoblasts and osteoclasts,exerting anti-osteoporosis *** to the previous research,the extract of Cibotium barumoz,Achyranthes bidentata,Curculigo orchioides,Epimedium brevicornum,Angelica sinensis,Polygonatum sibiricum,Dendrobium officinale,Morinda officinalis,Nelumbo mucifera,Diospyros kaki,Hordeum vulgare,Cistanche deserticola,Commiphora Myrrha and other plant-derived polysaccharides could benefit to the osteoblasts and *** essential mechanisms are mainly related to the activation or inhibition of many factors,including runt-related transcription factor 2(Runx2),B-catenin,osterix(Osx),activator protein-1(AP-1),osteocalcin(OCN/BGP),alkaline phosphatase(ALP),osteopontin(OPN),bone morphogenetic protein(BMP),phosphatidylinositol 3-kinase(PI3K)/C-Jun N-terminal kinase(JNK)/extracellular regulated protein kinase(ERK),osteoprotegerin(OPG),receptor activator of nuclear factor-kB(RANK),monocyte/macrophage colony-stimulating factor(M-CSF),tumor necrosis factor receptor-associated factor 6(TRAF-6),receptor activator of nuclear factor(NF)-KB ligand(RANKL),nuclear factor of activated T cells 1(NFATc1),c-Fos,matrix metallopeptidase-9(MMP-9),glycogen synthase kinase 3β(GSK3B)/B-catenin,nuclear factor E2-related factor 2(Nf2),as well as these related pathways,such as Wnt/p-catenin,BMP-2/SMAD1/5/8,PI3K/AKT,OPG/RANKL/RANK,NF-κB,MAPKs,*** plant-derived polysaccharides could improve the dynamic balance of bone formation and resorption through promoting the differentiation and maturation of osteoblast or inhibiting its *** reviewed plant-derived polysaccharides and their regulating mechanisms on the osteoclasts and osteoblasts provide the evidences for the development of osteoporosis therapeutics.

关键词： Osteoporosis Plant-derived polysaccharides Osteogenesis promotion Osteoclasts inhibition

Serum ferritin and the risk of early-onset colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3496-3506页

作者： Adam L Urback Kylee Martens Hannah Stowe McMurry Emerson Y Chen Caitlin Citti Anil Sharma adel Kardosh Joseph J Shatzel Division of Internal Medicine Oregon Health&Science UniversityPortlandOR 97239United States Division of Hematology and Medical Oncology Knight Cancer InstituteOregon Health&Science UniversityPortlandOR 97239United States Division of Gastroenterology&Hepatology Oregon Health&Science UniversityPortlandOR 97239United States

BACKGROUND The incidence of early-onset colorectal cancer(EO-CRC)is rising in the United States,and is often diagnosed at advanced *** serum ferritin is often incidentally discovered in young adults,however,the indication for endoscopy in EO-CRC is *** To compare serum ferritin between patients with EO-CRC and healthy controls(HCs),and examine the association of serum ferritin in EO-CRC with patient-and disease-specific *** A retrospective study of patients<50 years with newly-diagnosed EO-CRC was conducted from 1/2013-12/*** were included if serum ferritin was measured within 2 years prior to 1 year following CRC histologic *** supplement the analysis,a cohort of HCs meeting similar inclusion and exclusion criteria were identified for comparison.A sensitivity analysis including only patients with serum ferritin obtained at or before diagnosis was separately performed to minimize risk of *** Among 85 patients identified with EO-CRC(48 females),the median serum ferritin level was 26 ng/mL(range<1-2759 ng/mL).Compared to HCs(n=80211),there were a higher proportion of individuals with EO-CRC with serum ferritin<20 ng/mL(female 65%,male 40%)versus HCs(female 32.1%,male 7.2%)age 29-39 years(P=0.002 and P<0.00001,respectively).Stage IV disease was associated with significantly higher serum ferritin compared to less advanced stages(P<0.001).Serum ferritin obtained before or at the time of diagnosis was lower than levels obtained after *** findings were confirmed in the sensitivity *** Severe iron deficiency may indicate an increased risk of EO-CRC,particularly at earlier *** studies defining the optimal serum ferritin threshold and routine incorporation of serum ferritin in screening algorithms is essential to develop more effective screening strategies for EO-CRC.

关键词： Early-onset Young-onset Colorectal cancer Age Ferritin Iron deficiency

赛德西港用于船舶减排的陆上可再生能源供电评估

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哈尔滨工程大学学报（英文版） 2024年第2期23卷 506-524页

作者： Merna Makram Ameen M.Bassam adel A.Tawfik Waleed Yehia Naval Architecture and Marine Eng.Dept. Faculty of EngineeringPort Said UniversityPort Fuad 42526Egypt

Air pollution from shipping is becoming a critical issue,particularly in dense hub port *** proposed solution to minimize ship-based emissions at ports is the implementation of an Onshore Power Supply(OPS)*** allows ships to shut off their auxiliary engines and instead connect to the port *** there have been numerous studies conducted on ports in Europe and the United States,little research has been done on Egyptian ***,this paper aims to investigate the feasibility of implementing OPS at Port Said West Port in Egypt,aligning with Egypt Vision 2030’s goals for addressing climate *** research primarily focuses on analyzing data collected from calling ships to generate socio-economic and cost-effectiveness analyses of *** further enhance the environmental benefits of OPS,the paper proposes the use of solar energy as the OPS electricity *** findings of the study revealed that by relying on the national grid,emissions can be reduced by 28%.Moreover,it is predicted that this reduction could reach 100%if electricity generation is solely based on solar ***,the economic analysis demonstrates promising profitability,with a payback period of approximately two years.

关键词： Onshore power supply Port sustainability Shipping emissions inventory Solar energy Photovoltaic systems

Tangled web: Animal-human interaction and the rise of antibiotic resistance

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Infectious Diseases Research 2024年第1期5卷 1-2页

作者： adel Khalil Ibrahim Abeer Abdelnaser Awad Doaa Mohammad Ghaith Faculty of Veterinary Medicine Cairo UniversityGiza square 12211Egypt Faculty of Medicine Cairo UniversityAl-Manial 11559CairoEgypt.

Introduction Egypt is a Low-Middle Income Country(LMIC)with a population of 106,472,382 people in August 2022(Worldometers&Department of Economic and Social Affairs,2022).Available evidence suggests that there are misuse/overuse of antibiotic in Egypt[1].On recognizing the global threat of antibiotic resistance(AMR),Egypt launched the National Action Plan(NAP)in *** comprehensive plan,inspired by the Global Action Plan(GAP),united diverse stakeholders like ministries,universities,and international *** NAP tackled AMR through four key strategies:boosting public understanding of antibiotics,optimizing their use across humans and animals,embracing a“One Health”approach,and implementing effective infection prevention practices[2].

关键词： Action boosting resistance

Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis

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Cellular & Molecular Immunology 2024年第1期21卷 33-46页

作者： Anja Meyer Stephanie R.Zack Wes Nijim adel Burgos Vishwa Patel Brian Zanotti Michael V.Volin M.Asif Amin Myles J.Lewis Costantino Pitzalis Shiva Arami Joseph A.Karam Nadera J.Sweiss Shiva Shahrara Jesse Brown VA Medical Center ChicagoILUSA Department of Medicine Division of RheumatologyThe University of Illinois at ChicagoChicagoILUSA Department of Microbiology and Immunology Midwestern UniversityDowners GroveILUSA Division of Rheumatology and Clinical Autoimmunity Center of Excellence University of MichiganAnn ArborMIUSA Centre for Experimental Medicine and Rheumatology William Harvey Research InstituteBarts and The London School of Medicine and DentistryQueen Mary University of LondonLondonUnited Kingdom Centre for Experimental Medicine&Rheumatology William Harvey Research InstituteQueen Mary University of London and Barts NIHR BRC&NHS TrustLondonUK Department of Biomedical Sciences Humanitas Universityand Humanitas Research HospitalMilanItaly Department of Orthopedic Surgery the University of Illinois at ChicagoChicagoILUSA

A novel rheumatoid arthritis(RA)synovial fluid protein,Syntenin-1,and its receptor,Syndecan-1(SDC-1),are colocalized on RA synovial tissue endothelial cells and fibroblast-like synoviocytes(FLS).Syntenin-1 exacerbates the inflammatory landscape of endothelial cells and RA FLS by upregulating transcription of IRF1/5/7/9,IL-1β,IL-6,and CCL2 through SDC-1 ligation and HIF1α,or mTOR ***,Syntenin-1 orchestrates RA FLS and endothelial cell invasion via SDC-1 and/or mTOR *** Syntenin-1 reprogrammed endothelial cells,the dynamic expression of metabolic intermediates coincides with escalated glycolysis along with unchanged oxidative factors,AMPK,PGC-1α,citrate,and inactive oxidative ***,RA FLS rewired by Syntenin-1 displayed a modest glycolytic-ATP accompanied by a robust mitochondrial-ATP *** enriched mitochondrial-ATP detected in Syntenin-1 reprogrammed RA FLS was coupled with mitochondrial fusion and fission recapitulated by escalated Mitofusin-2 and DRP1 *** found that VEGFR1/2 and Notch1 networks are responsible for the crosstalk between Syntenin-1 rewired endothelial cells and RA FLS,which are also represented in RA *** to RA explants,morphological and transcriptome studies authenticated the importance of VEGFR1/2,Notch1,RAPTOR,and HIF1αpathways in Syntenin-1 arthritic mice and their obstruction in SDC-1 deficient ***,dysregulation of SDC-1,mTOR,and HIF1αnegated Syntenin-1 inflammatory phenotype in RA explants,while inhibition of HIF1αimpaired synovial angiogenic imprint amplified by *** conclusion,since the current therapies are ineffective on Syntenin-1 and SDC-1 expression in RA synovial tissue and blood,targeting this pathway and its interconnected metabolic intermediates may provide a novel therapeutic strategy.

关键词： Syntenin-1 Syndecan-1 RA FLS RA explants immunometabolism