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An integrative Tai Chi program for patients with breast cancer undergoing cancer therapy:study protocol for a randomized controlled feasibility study

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Journal of Integrative Medicine 2018年第2期16卷 99-105页

作者： Lizhou Liu Simone Petrich Blair McLaren Lyndell kelly g.David Baxter Centre for Health Activity and Rehabilitation ResearchSchool of PhysiotherapyUniversity of Otago Department of Surgical Sciences Southern District Health Board Oncology Department Southern District Health Board

Background： Breast cancer patients experience various side effects during cancer therapy, often resulting in reduced quality of life and poor adherence to treatment. A limited range of proven interventions has been developed to target such side effects. While Tai Chi offers benefits for the health and well-being of breast cancer survivors, the effectiveness of Tai Chi across the treatment continuum has not been evalu- ated. Improved patient education and support has been suggested as a priority for breast cancer care. This pilot study assesses the feasibility of a randomized controlled trial （RCT） to evaluate the effectiveness of ＂an integrative Tai Chi＂（ANITA） program for breast cancer patients undergoing cancer therapy. Methods/design： This is a single-centre, two-arm feasibility RCT. Twenty-four patients with breast cancer who have undergone surgical treatment will be recruited from the Dunedin Hospital （New Zealand） over a 12-month period （from August 2017 to July 2018）. Subject to informed consent, patients will be ran- domized to receive standard cancer treatment alone or standard cancer treatment plus the ANITA pro- gram, consisting of peer support, health education, and Tai Chi Ruler exercise. The program runs alongside the patient＇s adjuvant cancer therapy, which may include chemotherapy, radiation therapy, antibody treatment, and/or antihormonal therapy. Analysis in this study will focus on process evaluation of participant recruitment, retention, treatment fidelity, acceptability of the program, and occurrence of adverse events. Clinical outcomes （i.e., fatigue, sleep quality, anxiety and depression and quality of life） will be assessed at baseline, and at 12 weeks and 24 weeks post-randomization. Discussion： Outcomes from this study will inform the feasibility and methodology for a future fully- powered RCT.

关键词： Tai Chi Breast cancer Feasibility study Randomized controlled trial Peer support Health education

Molecular biomarkers for oxidative stress and neuronal damage in red-bellied pacu(Piaractus brachypomus)

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Aquaculture and Fisheries 2023年第6期8卷 720-726页

作者： Julian David Ortiz Munoz kelly Johanna Lozano Villegas Iang Schroniltgen Rondon Barragan Research group in Immunobiology and Pathogenesis Laboratory of Immunology and Molecular BiologyFaculty of Veterinary Medicine and ZootechnicsUniversidad Del TolimaSanta Helena HighsIbague-Tolima730006299Colombia Poultry Research group Laboratory of Immunology and Molecular BiologyFaculty of Veterinary Medicine and ZootechnicsUniversidad Del TolimaSanta Helena HighsIbague-Tolima730006299Colombia

Biomarkers are biological molecules that provide information about the physiological condition of an organism such as early signals of health *** aim of this study was to compare the relative gene expression of four molecular biomarkers related to oxidative stress,and neuronal damage in Piaractus brachypomus under three different conditions(exposure to chlorpyrifos(CPF),menthol and eugenol anesthesia,and brain injury).Bioinformatic analyses were conducted to design primers for the molecular biomarkers,then,the relative gene expression of COX1,gPX1,BDNF and CALB1 genes was measured by qPCR using brain tissue cDNA from the treated animals as template and 2-ΔΔCT method was ***1a gene was used as reference *** results showed a response to chemical stress in the CPF treatment samples where gPX1,BDNF and CALB1 genes were ***,in menthol/eugenol and brain injury treatments,no alterations in the relative gene expression were observed.

关键词： Menthol Eugenol Chlorpyrifos Brain injury gene expression

Off the Map with an Urban Explorer

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城市漫步（gBA版） 2022年第8期 30-35页

作者： Ned kelly 不详

There are people who get off the beaten track in China,and then there is greg *** in Poland,before moving to the UK,divorce from his wife followed by a trip to Cher no byl cha nged his life-one he now dedicates to UrbExz the exploration of abandoned spaces.

关键词： Explorer Map moving

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RECYCLINg REALITY

城市漫步（gBA版） 2023年第3期 40-47页

作者： Ned kelly 不详

Hungarian photojournalist I Nicky Almasy was a house photographer at That's Shanghai from 2009-2013,spending six years capturing the diversity of this ever-shifting city,from life in the old lanes to ultramodern skysc... 详细信息

关键词： REAL shifting journal

Six of Shanghai's Best Amateur Photographers

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城市漫步（gBA版） 2022年第1期 30-39页

作者： Ned kelly 不详

Here's how running the That's Shanghai Instagram account works:users hashtag their images#thatsshanghai and we pick out the best of them to‘regram',tagging the original photographer.

关键词： photograph running Best

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SHAN gHAI SIX

城市漫步（上海版、英文） 2022年第1期 30-39页

作者： Ned kelly 不详

Here's how running the That's Shanghai Instagram acount works:users hashtag their images #thatsshanghal and we pick out the best of them to‘regram',tagging the original *** the process,we found ourselves reposting so... 详细信息

关键词： absolutely process beyond

Off the Map with an Urban Explorer

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城市漫步（上海版、英文） 2022年第8期 30-35页

作者： Ned kelly 不详

There are people who get off the beaten track in China,and then there is greg *** in Poland,before moving to the UK,divorce from his wife followed by a trip to Chernobyl changed his life-one he now dedicates to UrbEx,the exploration of abandoned *** 2018,greg moved to China-an'UrbEx gold mine'-and amassed over 100,000 followers on Instagram,@gregabandoned.

关键词： Explorer moved Map

Cystic fibrosis patients on cystic fibrosis transmembrane conductance regulator modulators have a reduced incidence of cirrhosis

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World Journal of Hepatology 2022年第2期14卷 411-419页

作者： Mitchell L Ramsey Michael R Wellner Kyle Porter Stephen E Kirkby Susan S Li Luis F Lara Sean g kelly A James Hanje Lindsay A Sobotka Department of gastroenterology Hepatology and NutritionThe Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of gastroenterology Hepatology and NutritionThe Ohio State Wexner Medical CenterColumbusOH 43210United States Department of Biostatistics The Ohio State UniversityColumbusOH 43210United States Department of Pulmonary and Critical Care Medicine The Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Internal Medicine The Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of gastroenterology Hepatology and NutritionThe Ohio State UniversityColumbusOH 43210United States

BACKgROUND Cystic fibrosis transmembrane conductance regulator(CFTR)modulators significantly improve pulmonary function in patients with cystic fibrosis(CF)but the effect on hepatobiliary outcomes remains *** hypothesized that CF patients on CFTR modulators would have a decreased incidence of cirrhosis compared to patients not on CFTR modulators or on *** To investigate the effect of CFTR modulators on the development of cirrhosis in patients with *** A retrospective analysis was performed using Truven MarketScan from January 2012 through December 2017 including all patients with a diagnosis of *** were excluded if they underwent a liver transplantation or if they had other etiologies of liver disease including viral hepatitis or alcohol *** were grouped by use of CFTR modulators,ursodiol,dual therapy,or no *** primary outcome was development of ***-Meier curves estimated the incidence of cirrhosis and log-rank tests compared incidence curves between treatment *** A total of 7201 patients were included,of which 955(12.6%)used a CFTR modulator,529(7.0%)used ursodiol,105(1.4%)used combination therapy,and 5612(74.3%)used neither *** incidence of cirrhosis was 0.1%at 1 year and 0.7%at 4 years in untreated patients,5.9%and 10.1%in the Ursodiol group,and 1.0%and 1.0%in patients who received both *** patient treated with CFTR modulators alone developed *** on CFTR modulators alone had lower cirrhosis incidence than untreated patients(P=0.05),patients on Ursodiol(Pghest incidence of cirrhosis was found among patients treated with Ursodiol alone,compared to untreated patients(P<0.001)or patients on Ursodiol and CFTR modulators(P=0.01).CONCLUSION CFTR modulators are associated with a reduction in the incidence of cirrhosis compared to other therapies in patients with CF.

关键词： Cirrhosis Ursodiol Transmembrane Cystic fibrosis Market scan Cystic fibrosis related liver disease

Patient-reported dissatisfaction following second side in staged bilateral total knee arthroplasty: A systematic review

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World Journal of Orthopedics 2022年第11期13卷 1029-1037页

作者： Eric gruenberger Andrew S Bae Tyler kelly Brent A Ponce James Mcgrory The Hughston Foundation ColumbusGA 31909United States Department of Orthopedic Surgery Jack Hughston Memorial HospitalPhenix CityAL 36867United States Department ofOrthopedic Surgery Hughston Foundation and Jack Hughston Memorial HospitalColumbusGA 31909United States

BACKgROUND Around one third of patients who undergo total knee arthroplasty(TKA)will eventually have the contralateral knee *** patient satisfaction after staged bilateral total knee arthroplasty procedures performed on different days is reportedly similar to unilateral ***,in our anecdotal experience patients often report less satisfying outcomes following the second side.A cursory review of available literature tended to confirm that *** sought therefore to consolidate all of the available data on this issue to further investigate this *** To consolidate available published data revealing satisfaction scores among patients following staged bilateral TKA,and to evaluate the phenomenon of less satisfying results following *** A systematic review of available literature reporting on satisfaction with TKA1 and TKA2 after staged bilateral knee arthroplasty was undertaken using PubMed,google Scholar,and *** 427 records,five full-length articles met criteria for inclusion in the *** data were then extracted and assessed on the basis of the Reference Citation Analysis(https://***/).RESULTS A total of 1889 patients with an average age of 68(range:38–92)underwent staged bilateral TKA with outcomes reported at 1 year following each TKA with a mean 21.9 mo between surgeries(range:2 d to 14.5 years).Overall satisfaction with both knees was 83.70%(1581)and dissatisfaction with both knees was 2.75%(52).In the remaining 13.56%(256)who were dissatisfied with one side,61.0%were dissatisfied with TKA2,and 39.0%were dissatisfied with ***-reported outcome scores for TKA2 were frequently lower than TKA1 even in patients reporting overall satisfaction with both *** At 1-year follow-up,there was a 50%greater risk of dissatisfaction with TKA2 among the 13.56%of patients reporting dissatisfaction in one knee after staged bilateral *** the interval betwe

关键词： Staged Staggered Sequential Bilateral arthroplasty Total knee arthroplasty Patient-reported outcomes