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Training birdsong recognition using virtual reality

Virtual Reality & Intelligent Hardware 2021年第5期3卷 397-406页

作者： Carlos ARCE-LOPERA María JoséARIAS Gustavo corrales Department of Technology and Information Universidad IcesiCali 760046Colombia

Background In mega-biodiverse environments,where different species are more likely to be heard than seen,species monitoring is generally performed using bioacoustics ***,since bird vocalizations are reasonable estimators of biodiversity,their monitoring is of great importance in the formulation of conservation ***,birdsong recognition is an arduous task that requires dedicated training in order to achieve mastery,which is costly in terms of time and money due to the lack of accessibility of relevant information in field trips or even specialized *** technology based on virtual reality(VR)and spatial audio may improve species monitoring by enhancing information accessibility,interaction,and user *** This study used spatial audio,a Bluetooth controller,and a head-mounted display(HMD)to conduct an immersive training experience in *** moved inside a virtual world using a Bluetooth controller,while their task was to recognize targeted *** measured the accuracy of recognition and user engagement according to the User Engagement *** The experimental results revealed significantly higher engagement and accuracy for participants in the VR-based training system than in a traditional computer-based training *** four dimensions of the user engagement scale received high ratings from the participants,suggesting that VR-based training provides a motivating and attractive environment for learning demanding tasks through appropriate design,exploiting the sensory system,and virtual reality *** The accuracy and engagement of the VR-based training system were significantly high when tested against traditional *** research will focus on developing a variety of realistic ecosystems and their associated birds to increase the information on newer bird species within the training ***,the proposed VR-based training system must be tested with ad

关键词： Human computer interaction Virtual environment Birdsong Audio training User engagement

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A Non-Destructive Time Series Model for the Estimation of Cherry Coffee Production

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Computers, Materials & Continua 2022年第3期70卷 4725-4743页

作者： Jhonn Pablo Rodríguez David Griol Zoraida Callejas Juan Carlos corrales Telematics Engineering Group University of CaucaPopayán190002Colombia INRAE University of ToulouseUMR 1248 AGIRF-31326Castanet TolosanFrance Department of Software Engineering University of GranadaGranada18071Spain

Coffee plays a key role in the generation of rural employment in *** than 785,000 workers are directly employed in this activity,which represents the 26%of all jobs in the agricultural *** coffee growers estimate the production of cherry coffee with the main aim of planning the required activities,and resources(number of workers,required infrastructures),anticipating negotiations,estimating,price,and foreseeing losses of coffee production in a specific *** important processes can be affected by several factors that are not easy to predict(e.g.,weather variability,diseases,or plagues.).In this paper,we propose a non-destructive time series model,based on weather and crop management information,that estimate coffee production allowing coffee growers to improve their management of agricultural activities such as flowering calendars,harvesting seasons,definition of irrigation methods,nutrition calendars,and programming the times of concentration of production to define the amount of personnel needed for *** combination of time series and machine learning algorithms based on regression trees(XGBOOST,TR and RF)provides very positive results for the test dataset collected in real conditions for more than a *** best results were obtained by the XGBOOST model(MAE=0.03;RMSE=0.01),and a difference of approximately 0.57%absolute to the main harvest of 2018.

关键词： Cherry coffee production estimation learner approaches time series weather data crop management data

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Smart Contract to Traceability of Food Social Selling

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Computers, Materials & Continua 2023年第3期74卷 4703-4728页

作者： Cristian Valencia-Payan JoséFernando Grass-Ramírez Gustavo Ramirez-Gonzalez Juan Carlos corrales University of Cauca Calle 5#4-70190003Popayan-CaucaColombia

Traditionally,food sustainability has been considered solely in the stage of agricultural ***,globalization,the expansion of the food production industry,and the emergence of supermarket chains that control the retail food market require specific significant changes in supply chains in the food sector and,therefore,we need to address the economic,social,and environmental impacts of these *** the other hand,social selling has increased rapidly in recent years,with a further boom,following current events related to the coronavirus disease(COVID-19).This explosion of social sales,where there are usually no control and regulation entities,can bring problems associated with mishandling *** this paper,we expose how Blockchain technology supports the traceability of social sales by validating the data provided by the chain participants such as digital health passports,production and transport data in the sale process;the proposed solution generates recommendations on productmanagement considering the agreements previously made by the network *** evaluate the proposed smart contracts,we useHyperledger Caliper,obtaining an average throughput of 12.6 transactions per second and an average latency of 0.3 s for the asset update *** also use a study case to evaluate the proposed project platform’s selling-transport stage using Internet of Things(IoT)sensors.

关键词： Blockchain reliability smart contracts social selling traceability artisan sweets

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The Colider and Roosevelt olcanic rocks (sw amazonian craton): geochemistry and sm-nd isotope characteristics of a silicic large igneous province

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Acta Geochimica 2021年第6期40卷 1023-1049页

作者： Bruna Saar de Almeida Mauro César Geraldes Carlos Augusto Sommer Felipe corrales Antonio Joāo Paes de Barros Universidade do Estado do Rio de Janeiro Rio de JaneiroBrazil University of Geneva GenevaSwitzerland Universidade Federal do Rio Grande do Sul Rio Grande do SulBrazil METAMAT(Mato Grosso State Geological Survey) CuiabaBrazil

The volcanic rocks of the Colíder and Roosevelt formations are extensively exposed in the south-central portion of the Amazonian Craton where effusive and pyroclastic rocks have been *** units,topped by chemical sediments and oceanic facies as rhyolite and andesite lavas,rhyodacite,and porphyritic dacite,with frequent intercalations of pyroclastic and epiclastic ***-rock geochemistry for 55 samples of rhyolitic to andesitic composition suggests the involvement of fertile mantle-derived components with E-MORB to OIB *** analyzed rocks display calc-alkaline to shoshonitic affinity consistent with generation related to an active continental *** whole-rock Sm-Nd isotope data from selected felsic volcanic rocks of the Colíder and Roosevelt formations yield negative initial eNd values between–3 and–9,indicating the predominantly crustal nature of the parental magmas with early Archean to late Paleoproterozoic(ca.2.5–2.0 Ga)depleted mantle model ages.

关键词： Amazonian craton Geochemistry Sm-Nd isotopes Paleoproterozoic Volcanism

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Vaccines in Non-Small Cell Lung Cancer

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World Journal of Vaccines 2013年第1期3卷 19-24页

作者： Luis corrales-Rodriguez Normand Blais Denis Soulières Centre Hospitalier de l’Université de Montréal Hopital Notre-Dame Montréal Canada Hospital San Juan de Dios San José Costa Rica

Immunotherapy as an option of treatment in cancer has experienced an important development with the inclusion of vaccines. In lung cancer this type of treatment has emerged and vaccines can be classified in three groups: antigen-specific vaccines, tumor cell vaccines, and dendritic cell vaccines. Emepepimut (L-BLP25) and MAGE-A3 have been the vaccines most widely studied. Their promising results with benefit in survival and limited toxicity in preclinical and clinical trials have led to phase III trials with results eagerly awaited. Other vaccines have been investigated, but results were not favorable or are still pending. Hopefully, vaccines could be an additional instrument for the treatment of lung cancer in the adjuvant or metastatic setting as time will unveil the results of current and future trials.

关键词： Emepepimut-S Immunotherapy Lung Cancer MAGE-A3 NSCLC Review Vaccine

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Overview of Multidrug-Resistant Pseudomonas aeruginosa and Novel Therapeutic Approaches

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Journal of Biomaterials and Nanobiotechnology 2012年第4期3卷 519-527页

作者： Marilyn Porras-Gomez Jose Vega-Baudrit Santiago Nunez-corrales National Nanotechnology Laboratory LANOTEC National Center for Advanced Technology CeNATSan JoseCosta Rica E-Science Research Program Costa Rican Institute of TechnologyCartagoCosta Rica

Gram-negative bacilli Pseudomonas aeruginosa is an important pathogen in hospitalized patients, contributing to their morbidity and mortality due to its multiple resistance mechanisms. Therefore, as therapeutic options become restricted, the search for new agents is a priority. Latterly an accelerated increase in frequency of multidrug-resistant clinical strains has severely limited the availability of therapeutic options. Several in vitro and in vitro studies evaluating the efficacy of different antimicrobials agents and development of vaccines against P. aeruginosa have been reported as novel approaches, such as inhibition of virulence factor expression or inhibition of their metabolic pathways.

关键词： Bacilli Gram-Negative Pseudomonas aeruginosa Multidrug Resistance Pathogen Resistance Mechanisms

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Immobilization of Gold and Silver on a Biocompatible Porous Silicone Matrix to Obtain Hybrid Nanostructures

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Journal of Biomaterials and Nanobiotechnology 2018年第1期9卷 41-50页

作者： Solano-Umana Victor corrales Urena Yendry Regina Vega-Baudrit Jose Roberto Hologic Surgical Products Costa Rica AlajuelaCosta Rica National Laboratory of Nanotehcnology(LANOTEC-CeNAT-CONARE) San JoseCosta Rica

During the last decade an enormous research effort has been deployed with respect to porous materials. Design, pore size, shape, morphology and density are crucial features for increasing the surface area of silicone materials, aiming for a better biological response so cells can adhere and grow. Many medical applications utilize polydimethylsiloxane (PDMS) in medical implants, despite its hydrophobic surface that does not stimulate cellular adhesion. Porosity and morphology are important factors in the wettability of PDMS, but modifying the hydrophobic surface functionalization is required. To achieve this goal, the use of coatings with gold and silver nanoparticles or nanofilms can be used as a strategy to improve biocompatibility. This is due to the effect on mammalian cell adhesion and proliferation related to gold nanoparticles, as well as the prevention of infections related to silver nanoparticles. In this study, the pores in the silicone matrix were formed using sugar crystals as a template agent, and later passed through a lixiviation process to form a porous silicon matrix. Next, the matrix was placed inside a colloidal suspension;a process that allowed the immobilization of these particles on the surface matrix. A hybrid stable material was synthetized through this process. The water absorption level of the porous silicone matrix with and without the nanoparticles was determined. The water uptake of the matrix was higher when the nanoparticles were immobilized on the surface. Van der Waals and hydrogen bonding interactions account for this, promoting the retention of a higher concentration of water molecules. Higher water uptake has been identified as being a key factor for improving biological response, cellular adhesion and growth, which accelerates implant integration in the body.

关键词： Silicone Porous Gold Silver Water Absorption

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Synthesis and Determination of Antitumor Activity of Jacaranone and Synthetic Analogs

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International Journal of Organic Chemistry 2018年第1期8卷 115-124页

作者： María L. Arias Eugenia corrales Rebeca Poveda Jorge A. Cabezas ResearchCenter for Tropical Disease (CIET) and Faculty of Microbiology University of Costa Rica San José Costa Rica School of Chemistry University of Costa Rica San José Costa Rica

Natural product jacaranone, 1, and three analog derivatives were synthesized and their apoptotic and necrotic activity against four cancer cell lines was tested. One of these derivatives 7, was more active than the natural product, and exhibited an important necrotic effect against three of the cell lines tested (ovarian carcinoma, liver cancer and breast cancer cells). Derivative 6 was more active than the natural product, and showed a significant apoptotic activity against breast cancer and ovarian carcinoma cells. Some derivatives analyzed in this study showed promising anti-tumor results, nevertheless, further studies have to be done in order to determine their in vivo activity, their mechanism as well as their safety and stability.

关键词： Jacaranone Jacaranone Synthetic Analogs Antitumor Activity

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Evaluation of the Synergistic Effect of EDTA-Functionalized Chitosan Nanoparticles on Imipenem Delivery in Pseudomonas aeruginosa Carbapenem-Resistant Strain AG1

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Journal of Biomaterials and Nanobiotechnology 2018年第1期9卷 64-78页

作者： Marilyn Porras-Gomez Jose Vega-Baudrit Fernando Garcia Santiago Nunez-corrales Sergio Madrigal-Carballo National Nanotechnology Laboratory(LANOTEC) National Center for Advanced Technology Studies(CeNAT)San JoseCosta Rica Centro de Investigaciones en Enfermedades Tropicales(CIET) Facultad de MicrobiologiaUniversidad de Costa RicaSan PedroCosta Rica National Center for Biotechnological Innovations(CENIBiot) National Center for Advanced Technology Studies(CeNAT)San JoseCosta Rica

Metallo-β-lactamases are bacterial zinc-dependent enzymes involved in the hydrolysis of β-lactamic antibiotics representing the main cause of bacterial resistance to carbapenems, drugs of last resort for treating infections caused by multiresistant bacteria. We elaborated the hypothesis that it is possible to inhibit the enzymatic activity of metallo-β-lactamases by lowering the availability of zinc in the extracellular medium using metal chelating agents such as EDTA carried on nanoparticles. Chitosan, as linear cationic polysaccharide is frequently used in biomedical and pharmaceutical applications, has been studied as a biocompatible encapsulating agent in drug delivery systems and is an ideal transport agent for bioactive molecular complexes in antibiotic applications due to its ability to associate with negatively charged substances. We developed novel nanoparticles using chitosan as a transport matrix for β-lactamic antibiotics. Nanoparticles were synthesized according to the ion gelation method using tripolyphosphate as crosslinking agent. Nanoparticles were functionalized by the adsorption of EDTA, which acts as complexifying agent for Zn2+ ions causing inhibition of metallo-β-lactamases activity. We evaluate the antimicrobial effects of EDTA-functionalized nanoparticles with an imipenem cargo on the clinical isolate P. aeruginosa AG1, a carbapenem-resistant high-risk clone ST-111 carrying both blaIMP-18 and blaVIM-2 metallo-β-lactamases genes.

关键词： Chitosan EDTA Nanoparticles Drug-Resistant Imipenem

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Effect of a Protein-Energy Supplement of Low Consumption with Coconut Pulp Expeller (<i>Acrocomia aculeata</i>) of Beef Cattle at Pasture

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Open Journal of Animal Sciences 2020年第3期10卷 528-534页

作者： Julio Gonzalez Javier Kanazawa Patricia Coronel Gregorio Presentado María Paz corrales Patricia Criscioni Oscar Luis Valiente Department of Bromatology Nutrition and Animal Feeding Faculty of Veterinary Sciences National University of Asunción Asunción Paraguay Department of Animal Production Faculty of Veterinary Sciences National University of Asunción Asunción Paraguay

The purpose of this study is to evaluate the effect of a low consumption protein-energy supplement that incorporates 15% of coconut pulp expeller in bovine animals. These pasture fattening cattle were checked on daily weight gain, supplement consumption and efficiency of pasture use. This study was carried out in a livestock establishment in the Department of Concepción, Paraguay. A total of 108 animals were selected;castrated male bovines, 342 ± 30.2 of body weight (BW), age average 28 months, Nelore breed distributed in 2 treatments (T1 and T2): T1 = 42 animals;control group (pasture + conventional mineral salt) and T2 = 66 animals;treatment group with a protein-energy supplement (pasture + protein-energy supplement with minerals). In both treatments, the animals grazed on pasture of Brachiaria brizantha cv. Marandú and Panincum maximaun cv. Tanzania used a system of pasture rotation of 1 - 3 days of occupation and 35 - 40 days of rest. The average daily weight gain (DG) was 0.82 and 0.83 kg/day (p > 0.05), the supplement consumption was 0.1 and 0.28 kg/day per animal and the % disappearance of the biomass of 18 and 23% for T1 and T2, respectively. In conclusion, there was no evident effect on DG of protein-energy

关键词： Supplementation Protein-Energy Mineral Bovine Fattening

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