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Multi-head neural networks for simulating particle breakage dynamics

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Theoretical & Applied Mechanics Letters 2024年第2期14卷 130-141页

作者： abhishek gupta Barada Kanta Mishra School of Mechanical Sciences Indian Institute of Technology(IIT)GoaPonda 403401India School of Chemical and Materials Science Indian Institute of Technology(IIT)GoaPonda 403401India

The breakage of brittle particulate materials into smaller particles under compressive or impact loads can be modelled as an instantiation of the population balance integro-differential *** this paper,the emerging computational science paradigm of physics-informed neural networks is studied for the first time for solving both linear and nonlinear variants of the governing *** conventional methods,the proposed neural network provides rapid simulations of arbitrarily high resolution in particle size,predicting values on arbitrarily fine grids without the need for model *** network is assigned a simple multi-head architecture tailored to uphold monotonicity of the modelled cumulative distribution function over particle *** method is theoretically analyzed and validated against analytical results before being applied to real-world data of a batch grinding *** agreement between laboratory data and numerical simulation encourages the use of physics-informed neural nets for optimal planning and control of industrial comminution processes.

关键词： Particle breakage dynamics Population balance equation Physics-informed neural networks

Effects of defects on the electronic properties of WTe_2 armchair nanoribbons

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Journal of Semiconductors 2014年第11期35卷 10-15页

作者： Bahniman Ghosh abhishek gupta Bhupesh Bishnoi Microelectronics Research Center 10100Burnet RoadBldg.160University of Texas at AustinAustinTX78758USA Department of Electrical Engineering Indian Institute of Technology Kanpur

We have investigated the electronic properties of WTe2 armchair nanoribbons with defects. WTe2 nanoribbons can be categorized depending on the edge structure in two types： armchair and zigzag. WTe2 in its bulk form has an indirect band gap but nanoribbons and nanosheets of WTe2 have direct band gaps. Interestingly, the zigzag nanoribbon is metallic while the armchair nanoribbons are semiconducting. Thus they can find applications in device fabrication. Therefore, it is very important to study the effect of defects on the electronic properties of the armchair nanoribbons as these defects can impair the device properties and characteristics. We have considered defects such as： vacancy, rough edge, wrap, ripple and twist in this work. We report the band gap variation with these defects. We have also studied the change in band gap and total energy with varying degrees of wrap, ripple and twist.

关键词： electronic property WTe2 armchair nanoribbons defects

Improving Heat Transfer in Parabolic Trough Solar Collectors by Magnetic Nanofluids

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Energy Engineering 2024年第4期121卷 835-848页

作者： Ritesh Singh abhishek gupta Akshoy Ranjan Paul Bireswar Paul Suvash C.Saha Department of Applied Mechanics Motilal Nehru National Institute of Technology AllahabadPrayagrajIndia Department of Mechanical and Mechatronic Engineering University of Technology SydneySydneyAustralia

A parabolic trough solar collector(PTSC)converts solar radiation into thermal ***,low thermal efficiency of PTSC poses a hindrance to the deployment of solar thermal power *** performance of PTSC is enhanced in this study by incorporating magnetic nanoparticles into the working *** circular receiver pipe,with dimensions of 66 mm diameter,2 mm thickness,and 24 m length,is exposed to uniform temperature and velocity *** working fluid,Therminol-66,is supplemented with Fe3O4 magnetic nanoparticles at concentrations ranging from 1%to 4%.The findings demonstrate that the inclusion of nanoparticles increases the convective heat transfer coefficient(HTC)of the PTSC,with higher nanoparticle volume fractions leading to greater heat transfer but increased pressure *** thermal enhancement factor(TEF)of the PTSC is positively affected by the volume fraction of nanoparticles,both with and without a magnetic ***,the scenario with a 4%nanoparticle volume fraction and a magnetic field strength of 250 G exhibits the highest TEF,indicating superior thermal *** findings offer potential avenues for improving the efficiency of PTSCs in solar thermal plants by introducing magnetic nanoparticles into the working fluid.

关键词： Parabolic trough solar collector(PTSC) magnetic nanofluid(MNF) heat transfer convective heat transfer coefficient(HTC) thermal enhancement factor(TEF)

Multi-objective vehicle rebalancing for ridehailing system using a reinforcement learning approach

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Journal of Management Science and Engineering 2022年第2期7卷 346-364页

作者： Yuntian Deng Hao Chen Shiping Shao Jiacheng Tang Jianzong Pi abhishek gupta Department of Electrical and Computer Engineering The Ohio State UniversityColumbusOH43210USA

The problem of designing a rebalancing algorithm for a large-scale ridehailing system with asymmetric(unbalanced)demand is considered *** pose the rebalancing problem within a semi Markov decision problem(SMDP)framework with closed queues of vehicles serving stationary,but asymmetric demand,over a large city with multiple stations(representing neighborhoods).We assume that the passengers queue up at every station until they are matched with a *** goal of the SMDP is to minimize a convex combination of the waiting time of the passengers and the total empty vehicle miles *** resulting SMDP appears to be difficult to solve yielding closed-form expression for the optimal rebalancing ***,we use a deep reinforcement learning algorithm to determine the approximately optimal solution to the *** show through extensive Monte Carlo simulations that the trained policy outperforms other well-known state-dependent rebalancing strategies.

关键词： Reinforcement learning Ridehailing system Multi-objective optimization

Pharmacognostic Evaluation and Antioxidant Activity of <i>Urtica dioica</i>L.

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Chinese Medicine 2012年第3期3卷 128-135页

作者： Vertika Khare Pradeep Kushwaha Shikhar Verma abhishek gupta Sharad Srivastava AKS Rawat Pharmacognosy & Ethnopharmacology Division CSIR-National Botanical Research Institute Lucknow India

Background: Urtica dioica L. is a common Himalayan species which produces allergenic substances causing oedema and inflammation in humans. It has become a source of folk medicine for the treatment of many diseases. The leaves and roots both are used internally as a blood purifier and diuretic and an infusion of the plant is used for nasal and menstrual haemorrhage, diabetes, rheumatism, eczema, anaemia, hair loss, as an expectorant and antidiarrhoeal. Present study includes pharmacognostic evaluation, antioxidant activity and HPTLC analysis of Urtica dioica L. Methods: Pharmacognostic evaluation of aerial part of U. dioica has been performed as per Indian pharmacopoeia. In-vitro antioxidant evaluation of U. dioica has been performed using DPPH free radical scavenging activity. Ferulic acid, a potential phenolic antioxidant present in this species, has been studied through HPTLC. Results: U. dioica hydro-alcoholic extract shows positive results for antioxidant activity with IC50 value of 88.33 ± 2.88 μg/ml. Standard ascorbic acid showed IC50 value of 2.8 ± 0.62 μg/ml. Ferulic acid was identified at Rf 0.61 ± 0.01 and quantified to 0.73% in this species through CAMAG HPTLC analysis. Conclusion: The pharmacognostical parameters reported can be considered as quality standards of U. dioica in herbal industry. Hydro-alcoholic extract of U. dioica showed positive in vitro antioxidant activity. Presence of phenolic compound suggests that antioxidant activity may be due to ferulic acid content.

关键词： Antioxidant Activity DPPH Ferulic Acid HPTLC U. Dioica

Natural Products Potential and Scope for Modern Cancer Research

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American Journal of Plant Sciences 2013年第6期4卷 1270-1277页

作者： Rajeev Nema Sarita Khare Parul Jain Alka Pradhan abhishek gupta Dharmendra Singh Center for Microbiology & Bio-Technology Research and Training Institute Bhopal Bhopal India Government of Motilal Vigyan Mahavidyalaya Bhopal India. S.V. Polytechnic College Bhopal India Sarojini Naidu Government Girls Post Graduate (Autonomous) College Bhopal India Sarojini Naidu Government Girls Post Graduate (Autonomous) College Bhopal India

In the present time Natural products are considered to be symbols of protection in comparison to the synthetic product that are regarded as unsafe to human life and environment. Although a large number of synthetic drugs are being added to the world of present pharmacopoeia, but still no system of medicine in the world has been able to solve all the health problems, which include diseases like Cancer. Therefore the search for innovative therapeutic constituents from plants is genuine and urgent. In India, there is an ocean of knowledge about medicinal plants and rich medicinal flora, but still only a few pearls have been searched as therapeutic agents. There are large numbers of original plants left which have not been investigated thoroughly from modern scientific view or their healing values have not been known. Thus there is an insistent need for systematic phytochemical examination of those plants which have not been investigated scientifically. More research can be done to investigate the unknown and unexplored potential of plants. Further analysis of plants (active compounds) can be carried out by way of making use of different analytical methods such as HPTLC, HPLC, NMR and UV spectrophotometer analysis or computer based drug designing.

关键词： Medicinal Plant Natural Product Cancer Biology

快速负荷波动下支持最优潮流的进化型多任务处理架构（英文）

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南方电网技术 2017年第10期11卷 103-114页

作者： L. P. M. I. Sampath abhishek gupta Yew-Soon Ong H. B. Gooi 南洋理工大学跨学科研究生学院新加坡639798 南洋理工大学计算机科学与工程学院新加坡639798 南洋理工大学电机与电子工程学院新加坡639798

电力系统运行规划主要使用以小时为单位运行的机组组合。目前,可再生能源在用户侧的渗透率越来越高,导致电力系统负荷产生巨大波动。因此,为了维持电力系统运行的经济性和安全需求、确保电力供应的可靠性,我们有必要进行以小时为间隔的... 详细信息

电力系统运行规划主要使用以小时为单位运行的机组组合。目前,可再生能源在用户侧的渗透率越来越高,导致电力系统负荷产生巨大波动。因此,为了维持电力系统运行的经济性和安全需求、确保电力供应的可靠性,我们有必要进行以小时为间隔的最优潮流计算,并且考虑各种可能情况。传统的元启发法比较适合解决最优潮流问题,但是由于耗时太长,实际上并不实用。为此,本文提出了一种进化型多任务处理架构,根据不同负荷需求并行处理多个最优潮流问题。仿真结果表明该架构极大地提升了进化算法在最优潮流问题的利用率,与正统进化算法相比具有更快的计算速度。

关键词：进化算法进化型多任务处理元启发最优潮流

Androgen receptor in bladder cancer:A promising therapeutic target

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Asian Journal of Urology 2020年第3期7卷 284-290页

作者： abhishek Tripathi Shilpa gupta Section of Hematology Oncology University of Oklahoma Stephenson Cancer CenterOklahoma CityOKUSA Department of Hematology and Medical Oncology Cleveland Clinic Taussig Cancer InstituteClevelandOHUSA

There has been a significant progress in the treatment of metastatic urothelial carcinoma in the last few years with the advent of immunotherapy after a long gap of no drug approvals for over 4 *** immunotherapy with checkpoint inhibitors has revolutionized the treatment of urothelial carcinoma,unfortunately,only a minority of patients respond to *** options for patients who do not respond and/or progress on immunotherapy are very limited and overall prognosis remains dismal in metastatic urothelial *** first targeted therapy targeting the fibroblast growth factor receptor(FGFR)was recently approved for bladder cancer,but it is effective only in select patients harboring the FGFR2 and FGFR 3 *** drug conjugates like enfortumab vedotin have shown promising activity in clinical *** of novel targeted therapies remains an area of investigation and an unmet need in bladder *** of androgen receptor(AR)is a potential strategy for targeted drug development in bladder cancer.A significant proportion of urothelial carcinoma patients express AR irrespective of *** signaling in urothelial carcinoma has been linked to progression through multiple mechanisms,including activation of human epidermal growth factor receptor-2(EGFR or HER-2)signaling and epithelial to mesenchymal transition(EMT).Furthermore,AR is enriched in the luminal papillary mRNA subtype of urothelial carcinoma and also mediates resistance to cisplatin-based *** evidence suggests that AR inhibition can successfully inhibit urothelial carcinoma growth as monotherapy and is synergistic with cisplatin-based *** review the preclinical and clinical evidence supporting the putative role of AR signaling in urothelial carcinoma pathogenesis,progression and its role as a novel therapeutic target and future directions.

关键词： Androgen receptor Urothelial carcinoma Bladder cancer Targeted therapy Enzalutamide Cisplatin Testosterone

Use of a Bioaugmented Organic Soil Amendment in Combination with Gypsum for Withania somnifera Growth on Sodic Soil

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Pedosphere 2016年第3期26卷 299-309页

作者： Manjul gupta Pankaj Kumar SRIVASTAVA SHIKHA abhishek NIRANJAN Shri Krishna TEWARI CSIR National Botanical Research Institute Rana Pratap Marg Lucknow 226001 (India) School of Environmental Sciences Babasaheb Bhimrao Ambedkar University Vidya Vihar Rae Bareilly Road Lucknow 226025 (India)

Limited availability of organic matter is a problem to sustain crop growth on sodic soil. Organic soil amendments are a costeffective source of nutrients to enhance crop growth. A field study was conducted to evaluate the effect of an organic soil amendment bioaugmented with plant growth-promoting fungi(SF_(OA) ) in combination with gypsum on soil properties and growth and yield attributes of Withania somnifera, one of the most valuable crops of the traditional medicinal system in the world, on a sodic soil at the Aurawan Research Farm of CSIR-National Botanical Research Institute, Lucknow, India. The SF_(OA) used was prepared by pre-enriching farm waste vermicompost with plant growth-promoting fungi before mixing with pressmud and Azadirachta indica seed cake. The application of SF_(OA) at 10 Mg ha^(-1)after gypsum(25.0 Mg ha^(-1)) treatment significantly(P < 0.05) increased root length(by 96%) and biomass(by 125%) of Withania plants compared to the control without SF_(OA) and gypsum. Similarly, the highest withanolide contents were observed in leaves and roots of Withania plants under 10 Mg ha^(-1)SF_(OA) and gypsum. Combined application of SF_(OA) and gypsum also improved physical, chemical and enzymatic properties of the soil, with the soil bulk density decreasing by 25%, water-holding capacity increasing by 121%, total organic C increasing by 90%, p H decreasing by 17% and alkaline phosphatase, β-glucosidase, dehydrogenase and cellulase activities increasing by 54%, 128%, 81% and 96%, respectively, compared to those of the control. These showed that application of the SF_(OA) tested in this study might reclaim sodic soil and further support Withania cultivation and results were better when the SF_(OA) was applied after gypsum treatment.

关键词： medicinal crop plant growth-promoting fungi soil property soil reclamation vermicompost