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Neural Regeneration Research 2024年第7期19卷 1433-1434页

作者： Camila m.Freria Paul Lu Department of Neurosciences University of CaliforniaSan DiegoLa JollaCAUSA Veterans Administration San Diego Healthcare System San DiegoCAUSA

Efforts to promote recovery of function after human spinal cord injury(SCI) will likely require interventions to rgeting the corticospinal tract(CST) motor system:the most important pathway for voluntary motor control in *** system has historically been the most refractory to regenerative efforts after *** "nonregeneration" of the CST changed when robust regeneration of the CST into spared tissue was demonstrated by the inactivation of phosphatase and tensin homolog and delivery of inosine.

关键词： cervical progenitor injury

modern View on Potentials of Forensic Pharmaceutical and Pharmacological Expertise

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Journal of Forensic Science and medicine 2024年第1期10卷 62-67页

作者： Elena m.Vazhnichaya Nataliia m.Deviatkina Department of Pharmacology Clinical Pharmacology and PharmacyPoltava State Medical UniversityPoltavaUkraine

The great number of drugs and their variety have increased the potential of therapy but increased the risks of crimes related to the production,sale,and use of *** prosecution of such crimes requires pharmaceutical or pharmacological *** development of forensic pharmacy and forensic pharmacology is relevant and needs consideration of their modern *** purpose of the work is to analyze literature data on the scientific basis of forensic pharmaceutical and pharmacological expertise and their modern *** texts of articles,book chapters,and websites were studied using keywords relevant to the purpose of the *** is shown,that modern forensic pharmaceutical expertise is a separate type of expertise that focuses on the study of drugs and documents that regulate the production,distribution,and quality of *** uses the latest analytical methods of pharmacy.A pharmacologist analyzes body fluids and tissues and interprets the resulting data to help courts and investigators assess the role of a drug in the person’s behavior,illness,injury,or *** range of issues included in the pharmacological examination is fully within the competence of the forensic medical examination,which can be appointed in civil cases or criminal proceedings connected with harm to health or *** pharmacology is not the same as forensic toxicology or pharmacovigilance and requires a separate approach based on purely pharmacological knowledge.

关键词： Drug expertise forensic pharmacology forensic pharmacy

Fuel cell stack design and modelling with a double-stage boost converter coupled to a single-phase inverter

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Clean Energy 2024年第1期8卷 188-196页

作者： Basem E.Elnagi Ahmed m.Ismaiel Hany S.E.mansour m.N.Abd-Alwahab Electrical Engineering Department Faculty of EngineeringSuez Canal UniversityIsmailia 41522Egypt

A comprehensive proton-exchange membrane fuel cell stack model was developed and integrated with a two-stage DC/DC boost *** was directly coupled to a single-phase(two levels-four pulses)inverter without a *** pulse-width modu-lation signal was used to independently regulate every converter *** converter was modelled using a mATLAB®/Simulink®environment and an appropriate voltage control *** analysis features of the suggested circuit were created and,through established experiments,the simulation results were verified.A single-phase(two levels-four pulses)inverter control circuit was tested and it produced a pure sinusoidal waveform with voltage *** matches the voltage of the network in terms of amplitude and frequency.A sinusoidal pulse-width modulation approach was performed using a single-phase(two levels-four pulses)pulse-width modulation *** results demonstrated an enhancement in the standard of the output wave and tuned the dead time with a reduction of 63μs compared with 180μs in conventional techniques.

关键词： PEm fuel cell pulse-width modulation single-phase inverter and double-stage DC/DC boost converter

Thriving green havens in baking deserts:Plant diversity and species composition of urban plantations in the Sahara Desert

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Journal of Arid Land 2024年第9期16卷 1270-1287页

作者： mohammed SOUDDI Haroun CHENCHOUNI m'hammed BOUALLALA Laboratory of Saharan Natural Resources Faculty of Nature and Life SciencesUniversity of Ahmed Draia-AdrarAdrar 01000Algeria Laboratory of Algerian Forests and Climate Change Higher National School of ForestsKhenchela 40000Algeria Laboratory of Natural Resources and management of Sensitive Environments University of Oum El BouaghiOum El Bouaghi 04000Algeria Higher School of Saharan Agriculture Adrar 01000Algeria

Hot arid zones represent vital reservoirs of unique species and ecosystems,holding significant importance for *** study aimed to explore the plant diversity associated with tree plantations in urban ecosystems under hyper-arid climatic conditions in the Sahara Desert of *** may 2022,30 quadrats measuring 1 m^(2) each were established at the base of Phoenix dactylifera,Leucaena leucocephala,and Tamarix aphylla,corresponding to the dominant tree species in each of three *** each quadrat,the plant quantitative inventory was conducted to measure plant diversity and similarity among the studied *** on this,we assessed the plant functional traits and rarity/abundance status of the *** findings revealed a diverse flora associated with the studied plantations,comprising 29 plant species grouped into 27 genera and 12 ***,Poaceae(accounting for 30.8% of the flora),Asteraceae(25.0%),and Zygophyllaceae(21.6%)were *** an overall density of approximately 555 individuals/m^(2),Zygophyllum album(120 individuals/m^(2))and Polypogon monspeliensis(87 individuals/m^(2))emerged as the most abundant *** trait analysis underscored the pivotal role of therophytes(constituting over 50.0% of the flora)and anemochorous species(33.0%-62.5%).Phytogeographic analysis emphasized the prevalence of the Saharo-Arabic element(constituting over 31.0% of the flora)and the mediterranean Saharo-Arabic element(9.5%-21.5%).The Cosmopolitan element thrived under disturbance factors,recording percentages from 13.0% to 20.0% of the plant *** rarity/abundance status of the flora emphasized the significance of rare,common,and very common species in the studied *** findings could provide fundamental data for the effective control and management of biodiversity in hot hyper-arid urban ecosystems.

关键词： urban plantations plant diversity plant functional traits rarity/abundance status Sahara Desert Algeria

Nonuniform Dependence on the Initial Data for Solutions of Conservation Laws

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Communications on Applied mathematics and Computation 2024年第1期6卷 489-500页

作者： John m.Holmes Barbara Lee Keyfitz Department of mathematics The Ohio State UniversityColumbusOH43210USA

In this paper,we study systems of conservation laws in one space *** prove that for classical solutions in Sobolev spaces H^(s),with s>3/2,the data-to-solution map is not uniformly *** results apply to all nonlinear s... 详细信息

关键词： Conservation laws Data-to-solution map Nonuniform dependence

Sparse-Grid Implementation of Fixed-Point Fast Sweeping WENO Schemes for Eikonal Equations

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Communications on Applied mathematics and Computation 2024年第1期6卷 3-29页

作者： Zachary m.miksis Yong-Tao Zhang Department of Applied and Computational mathematics and Statistics University of Notre DameNotre DameIN46556USA

Fixed-point fast sweeping methods are a class of explicit iterative methods developed in the literature to efficiently solve steady-state solutions of hyperbolic partial differential equations(PDEs).As other types of fast sweeping schemes,fixed-point fast sweeping methods use the Gauss-Seidel iterations and alternating sweeping strategy to cover characteristics of hyperbolic PDEs in a certain direction simultaneously in each sweeping *** resulting iterative schemes have a fast convergence rate to steady-state ***,an advantage of fixed-point fast sweeping methods over other types of fast sweeping methods is that they are explicit and do not involve the inverse operation of any nonlinear local ***,they are robust and flexible,and have been combined with high-order accurate weighted essentially non-oscillatory(WENO)schemes to solve various hyperbolic PDEs in the *** multidimensional nonlinear problems,high-order fixed-point fast sweeping WENO methods still require quite a large amount of computational *** this technical note,we apply sparse-grid techniques,an effective approximation tool for multidimensional problems,to fixed-point fast sweeping WENO methods for reducing their computational ***,we focus on fixed-point fast sweeping WENO schemes with third-order accuracy(Zhang et al.2006[41]),for solving Eikonal equations,an important class of static Hamilton-Jacobi(H-J)*** experiments on solving multidimensional Eikonal equations and a more general static H-J equation are performed to show that the sparse-grid computations of the fixed-point fast sweeping WENO schemes achieve large savings of CPU times on refined meshes,and at the same time maintain comparable accuracy and resolution with those on corresponding regular single grids.

关键词： Fixed-point fast sweeping methods Weighted essentially non-oscillatory(WENO)schemes Sparse grids Static Hamilton-Jacobi(H-J)equations Eikonal equations

A Reputation-Based AODV Protocol for Blackhole and malfunction Nodes Detection and Avoidance

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Computers, materials & Continua 2024年第8期80卷 1867-1888页

作者： Qussai m.Yaseen monther Aldwairi Ahmad manasrah Artificial Intelligence Research Center(AIRC) College of Engineering and Information TechnologyAjman UniversityAjman346United Arab Emirates Department of Computer Information Systems Faculty of Computer and Information TechnologyJordan University of Science and TechnologyIrbid22110Jordan College of Technological Innovation Zayed UniversityAbu Dhabi144534United Arab Emirates Faculty of Information Technology and Computer Science Yarmouk UniversityIrbid21163Jordan Computer Information Systems Higher Colleges of TechnologySharjah341214United Arab Emirates

Enhancing the security of Wireless Sensor Networks(WSNs)improves the usability of their ***,finding solutions to various attacks,such as the blackhole attack,is crucial for the success of WSN *** paper proposes an enhanced version of the AODV(Ad Hoc On-Demand Distance Vector)protocol capable of detecting blackholes and malfunctioning benign nodes in WSNs,thereby avoiding them when delivering *** proposed version employs a network-based reputation system to select the best and most secure path to a *** achieve this goal,the proposed version utilizes the Watchdogs/Pathrater mechanisms in AODV to gather and broadcast reputations to all network nodes to build the network-based reputation *** minimize the network overhead of the proposed approach,the paper uses reputation aggregator nodes only for forwarding reputation ***,to reduce the overhead of updating reputation tables,the paper proposes three mechanisms,which are the prompt broadcast,the regular broadcast,and the light broadcast *** proposed enhanced version has been designed to perform effectively in dynamic environments such as mobile WSNs where nodes,including blackholes,move continuously,which is considered a challenge for other *** the proposed enhanced protocol,a node evaluates the security of different routes to a destination and can select the most secure routing *** paper provides an algorithm that explains the proposed protocol in detail and demonstrates a case study that shows the operations of calculating and updating reputation values when nodes move across different ***,the paper discusses the proposed approach’s overhead analysis to prove the proposed enhancement’s correctness and applicability.

关键词： AODV blackhole malfunction nodes pathrater reputation system wireless sensor networks(WSNs) watchdogs

Clinical implications of reconsideration of enthesitis/enthesopathy/enthesial erosion,as tendon attachmentlocalized avulsions and stress fracture equivalents

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World Journal of Orthopedics 2024年第10期15卷 902-907页

作者： Bruce m Rothschild Department of medicine Indiana University Ball Memorial HospitalMuncieIN 47303United States

Recognizing the mechanical origin of enthesitis/enthesopathy and the avulsion-nature of what had previously been considered erosions,it seems inappropriate to attribute it to stresses related to a person’s normal ***,sudden or unconditioned repetitive stresses appears the more likely *** of enthesial reaction have lacked standardization as to findings present among individuals who appear to be *** evaluation by palpation and mani-pulation may be as effective as application of radiologic *** of the mechanical nature of the disease,including individuals with inflammatory arthritis suggests prescription of mechanical solutions that reduce stresses across the involved enthesis.

关键词： Enthesitis Epicondylitis Erosion Avulsion Clinical examination

Poly(A)-specific RNase(PARN)generates and regulates miR-125a-5p 3’-isoforms,displaying an altered expression in breast cancer

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Signal Transduction and Targeted Therapy 2024年第5期9卷 1805-1807页

作者： Luisa Tomasello Shoshanah m.Holub Giovanni Nigita Rosario Distefano Carlo m.Croce Department of Cancer Biology and Genetics The Ohio State UniversityColumbusOHUSA Department of Internal medicine Division of HematologyThe Ohio State UniversityColumbusOHUSA

Dear Editor,microRNAs(miRNAs)are small non-coding RNAs crucial for post-transcriptional gene regulation,processed from primary miRNA transcripts by Drosha and Dicer.1 Latest advancements in Next Generation Sequencing highlighted the existence of miRNA isoforms(isomiRs)resulting from alternative processing,RNA editing,or post-transcriptional modifications.

关键词： breast cancer advancement

Dust particle surface potential in an argonhelium plasma using the(r,q)-distribution function

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Communications in Theoretical Physics 2024年第9期76卷 141-148页

作者： Bahaaudin m Raffah A A Abid Abdullah Khan Amin Esmaeili Yas Al-Hadeethi m N S Qureshi Department of Physics Faculty of SciencesKing Abdulaziz UniversityJeddah 21589Saudi Arabia Lithography in Devices Fabrication and Development Research Group Deanship of Scientific ResearchKing Abdulaziz UniversityJeddah 21589Saudi Arabia Joint Laboratory of Plasma Application Technology Institute of Advanced TechnologyUniversity of Science and Technology of ChinaHefei230026China CAS Key Laboratory of Geospace Environment University of Science and Technology of ChinaHefei230026China Department of Physics Zhejiang Normal UniversityJinhua321005China Department of Physics Graduate School of ScienceTokyo Metropolitan UniversityMinami-Osawa 1-1Hachioji City192-0397Japan Department of Physics GC UniversityLahore 54000Pakistan

In this paper,the dust particle surface potential for argon-helium plasma is evaluated analytically and numerically in the context of negatively charged dust particles by employing a power-law(r,q)-distribution *** studies have reported the argon-helium plasma and conducted a brief theoretical and experimental *** deepen our understanding further,this study aims to analyze the argon-helium plasma comprehensively using the same pattern but with the(r,q)-distribution *** this purpose,the current balance equations are derived for electron,helium and argon ions,when these charge species attain the quasineutrality *** numerically examined the currents of plasma species for a broad range of effective distribution function parameters r and *** is revealed that the surface potential of dust particles is significantly affected by the parameters r and q,helium ion-to-electron temperature ratio,argon ion-to-electron temperature ratio,and helium ion to argon ion number density *** incorporating the multi-ion(argon-helium)species,the significance of low-temperature nonmaxwellian dusty(complex)plasma is briefly examined.

关键词： dusty plasma dust charge potential plasma physics helium argon plasma r q distribution function non-maxwellian distribution