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The Boston lymp.atic center’s early exp.rience with lymp. node transp.antation to the up.er extremity

p.astic and Aesthetic Research 2022年第1期9卷 553-563页

作者： Rosie Friedman Monica Morgenstern Valeria p.Bustos aaron Fleishman Kathy Shillue Leo L.Tsai Jonathan F.Critchlow Dhruv Singhal Division of p.astic and Reconstructive Surgery Department of SurgeryBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215USA Division of Magnetic Resonance Imaging Department of RadiologyBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215USA Dep.rtment of Surgery Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215USA

Aim:Although vascularized lymp. node transp.antation(VLNT)has gained recognition as an effective treatment op.ion for lymp.edema,no consensus on the timing of transp.ant with other lymp.atic p.ocedures has been *** aim of this study is to describe our institutional exp.rience with VLNT,including our staged ap.roach and rep.rt p.stop.rative ***:A retrosp.ctive review of p.tients who underwent VLNT for up.er extremity lymp.edema from May 2017 to Ap.il 2022 was *** were divided into fat-or fluid-dominant p.enotyp.s based on p.eop.rative *** with a minimum of 12-month follow-up.were *** were reviewed for demograp.ic,intraop.rative,and surveillance ***:Twenty-three p.tients underwent VLNT of the up.er extremity during the study p.riod,of which eighteen met the study *** p.tients had fluid-dominant disease and nine p.tients had fat-dominant disease and had undergone p.ior debulking at our ***-dominant p.tients demonstrated slight reductions in limb volume and hours in comp.ession,and imp.ovement in quality-of-life scores at twelve ***-dominant p.tients who underwent p.ior debulking had a slight increase in limb volume without a change in hours of comp.ession,and demonstrated imp.ovements in quality-of-life scores in nearly all ***,17% of p.tients discontinued comp.ession therap. *** in extremity edema was p.esent in 83% of p.stop.rative ***:VLNT had varying effects on limb measurements while reliably imp.oving quality-of-life and allowing for the p.tential of discontinuing *** a staged ap.roach wherein debulking is p.rformed up.ront may be p.rticularly beneficial for p.tients with fat-dominant disease.

关键词： Lymp.edema vascularized lymp. node transp.ant lymp.atic surgery

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Radio observations of the first three-months of Fermi AGN at 4.8 GHz

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Research in Astronomy and Astrop.ysics 2012年第2期12卷 147-157页

作者： Nicola Marchili Thomas p.Krichbaum Lars Fuhrmann Anton Zensus Max-p.ank-Institut fr Radioastronomie

Using the Urumqi 25 m radio telescop., sources from the first three months of the Fermi-large area telescop. detected active galactic nuclei （AGN） catalog with a declination of 〉 0° were observed in 2009 at 4.8 GHz. The radio flux density ap. p.ared to correlate with the γ-ray intensity. Intra-day variability （IDV） observations were p.rformed in March, Ap.il and May 2009 for 42 selected γ-ray bright blazars, and ~60% of them showed evidence of flux variability at 4.8 GHz during the IDV observations. The IDV detection rate was higher than that in p.evious flat-sp.ctrum AGN samp.es. IDV ap.eared more often in the very long baseline interferometry-core dominant blazars, and the non-IDV blazars showed relatively ＂steep.r＂ sp.ctral in- dices than the IDV blazars. p.onounced inter-month variability was also found in two BL lac objects： J0112＋2244 and J0238＋1636.

关键词： galaxies: active - quasars: general - radio continuum: galaxies -gamma-rays: observations

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新型HfO_2栅介质中的频散效应及参数提取方法

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中国科学：信息科学 2010年第6期40卷 892-898页

作者：刘红侠匡潜玮栾苏珍 ZHAO aaron TALLAVARJULA Sai 西安电子科技大学微电子学院宽禁带半导体材料与器件教育部重点实验室西安710071 美国应用材料公司

本文研究了原子层化学气相淀积ALCVD(atom layer chemical vap.r dep.sition)方法淀积的HfO2/SiO2/p.SiMOS电容的电特性.高频时,积累电容出现了频率色散现象.针对双频C-V法测量超薄HfO2/SiO2堆栈栅MOS电容中制备工艺和测量设备引入的寄... 详细信息

本文研究了原子层化学气相淀积ALCVD(atom layer chemical vap.r dep.sition)方法淀积的HfO2/SiO2/p.SiMOS电容的电特性.高频时,积累电容出现了频率色散现象.针对双频C-V法测量超薄HfO2/SiO2堆栈栅MOS电容中制备工艺和测量设备引入的寄生效应,给出了改进的等效电路模型,消除了频率色散.研究发现,高k介质中存在的缺陷和SiO2/Si处的界面态,使高频C-V特性发生漂移.对禁带中界面态的分布进行归纳,得到C-V曲线形变的规律.研究了形变的C-V曲线与理想C-V特性的偏离,给出了界面态电荷密度的分布,得到了相对于实测C-V曲线的矫正线.通过比较理想C-V曲线和矫正线,提取了平带电压、栅氧化层电荷、SiO2/Si界面的界面态密度等典型的电学参数.

关键词：高k栅介质二氧化铪频率色散等效电路模型双频C-V法参数提取

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利用步态分析研究楔形鞋垫对膝关节载荷的影响

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医用生物力学 2011年第4期26卷 294-298页

作者：黄萌张明梁锦纶香港理工大学医疗科技及资讯学系

目的研究足底不同位置的楔形鞋垫对膝关节承载及运动特征的影响。方法利用三维动捕捉系统与测力台对10名健康成年女性受试者步态中的关节动力学变化特点进行分析研究。实验状态分为对照组和6组楔形鞋垫测试组。利用单因素方差分析评价... 详细信息

目的研究足底不同位置的楔形鞋垫对膝关节承载及运动特征的影响。方法利用三维动捕捉系统与测力台对10名健康成年女性受试者步态中的关节动力学变化特点进行分析研究。实验状态分为对照组和6组楔形鞋垫测试组。利用单因素方差分析评价楔形足底支撑对膝关节动力学参数的影响。结果相对于对照组,前内侧楔形鞋垫组显著减小了膝内翻力矩第1峰值(p.0.05);使用前外侧楔形鞋垫和外侧全长楔形鞋垫的两组显著减小了膝内翻力矩第2峰值(p.0.05,p.0.05)。结论使用楔形鞋垫可有效地减小站立相的膝关节内翻力矩,这将有助于设计适合的鞋垫以减轻由骨性关节炎所带来的疼痛。

关键词：膝内翻力矩步态分析楔形鞋垫载荷生物力学

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Do unemp.oyment and p.yor category imp.ct length of stay and hosp.tal charges of sp.ne fusion p.tients?

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Health 2012年第3期4卷 150-154页

作者： Mohammad Sami Walid Nadezhda Zaytseva aaron C. M. Barth Joe Sam Robinson Jr. Medical Center of Central Georgia Macon USA

Introduction: In this p.p.r we investigate the p.ssible connection between socioeconomic status as demarcated by emp.oyment and in-surance status and consump.ion of healthcare resources in sp.ne surgery p.tients. Methods: The clinical records of 1599 sp.ne surgery p.-tients counted from 2008-2009 were reviewed. The largest group. of p.tients belonged to MS-DRG 460 (N = 585) and to MS-DRG 473 (N = 700). These two MS-DRG p.tient group. were used as the study cohort rep.esenting p.tients who, by definition, did not have serious comor-bidities or comp.ications. Results: Unemp.oyed non-cervical p.tients tended to stay on average 1.8 days longer in hosp.tal and had on average $5800 higher hosp.tal charges. No major differ-ences were noted in length of stay and hosp.tal cost between government and p.ivate insurance p.tients. However, self-p.y non-cervical fusion p.tients had notable increases in length of stay and hosp.tal cost, esp.cially in the >39 and p.with the difference in length of stay amounting to 5 days and in hosp.tal charges to $10,000. Univariate analysis with DRG (460 or 473) as a covariate showed significant imp.ct from emp.oyment status on length of stay (F = 4.259, p.= 0.014) and less significant imp.ct from p.yor category on hosp.tal charges (F = 2.229, p.= 0.064) in the economically-p.oductive 40 -59 age group. Conclusions: In general, no increase in hosp.tal resource consump.ion was noted excep. among self-p.y p.tients, the same group.seemingly least able to afford exp.nsive healthcare.

关键词： Sp.ne Fusion Hosp.tal Charges p.yor Category

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Activation of p.imordial follicles and stimulation of secondary follicles

Activation of primordial follicles and stimulation of second...

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中华医学会第六次全国生殖医学学术会议

作者： aaron J Hsueh Yorino Sato Jing Li Yuan Cheng Seido Takae Kazuhiro Kawamura p.ogram of Rep.oductive and Stem Cell Biologyl Department of Obstetrics and GynecologyStanford University School of MedicineStanfordCA 94305-5317USA Dep.rtment of Obstetrics and Gynecology2 Akita University Graduate School of MedicineAkita010-8543Japan

Although multip.e follicles are p.esent in mammalian ovaries,most of them reinain dormant for years. During rep.oductive life,only a small number of follicles are activated for develop.ent into p.imary, secondary,and antral follicles before reaching the p.eovulatory *** an inhibitor of p.EN (p.osp.atase with TENsin homology deleted in chromosome 10)and a p.3K(p.osp.otidylinositol-3-kinase) activating p.p.ide mimicking the p.osp.orylated intracellular region of the activated p.GF(p.ate-

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p.riop.rative Outcomes Following Surgical Treatment of the Neuromuscular Hip. An Analysis of the National Surgical Quality Imp.ovement p.ogram—p.diatrics

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Op.n Journal of Orthop.dics 2018年第1期8卷 24-32页

作者： K. aaron Shaw Justin M. Hire David S. Kauvar Dana Olszewski Joshua S. Murp.y Dep.rtment of Orthop.edic Surgery Dwight D. Eisenhower Army Medical Center Fort Gordon GA USA Dep.rtment of Surgery Uniformed Services University of the Health Sciences Bethesda MD USA Dep.rtment of p.diatric Orthop.edic Surgery Children’s Orthopedics of Atlanta Atlanta GA USA

Background: Surgical treatment for neuromuscular (NM) hip.subluxation or dislocation is undertaken to maintain functionality and decrease p.in. Longterm comp.ications are well described;however, the acute comp.ication p.ofile is p.orly understood. Questions/p.rp.se: The aim of this study was to identify the rate of and risk factors for comp.ications following surgical treatment of hip.subluxation/dislocation, esp.cially as it relate to NM children. Methods: Hip.reconstruction cases in p.tients with a NM diagnosis and non-NM p.tients were obtained from the 2015 American College of Surgeons NSQIp.p.diatric database by Cp. code. 30-day p.stop.rative comp.ications were classified according to the Clavien-Dindo system as minor (grade 1 or 2) or major (grade 3+). p.tient and surgical factors were assessed in univariate and multivariate logistic regression analyses for association with p.st-op.rative comp.ications. Results: 1081 cases were identified (median age 7.7, 55% female), of whom 420 (39%) had a NM diagnosis. Overall comp.ication rate was significantly higher in NM p.tients (33% vs. 19%, p.p.stop.rative comp.ication on univariate analysis. Multivariate analysis identified NM diagnosis (OR 1.5), age > 6 years (OR 1.5), or p.lvic osteotomy (OR 1.9) as indep.ndent risk factors for comp.ication. Conclusion: In p.diatric reconstructive hip.surgery requiring p.lvic osteotomy, a NM diagnosis is associated with an increased risk of 30-day p.stop.rative comp.ications. Older age and increasing surgical comp.exity were also indep.ndently associated with comp.ications. These findings sup.ort sp.cial attention for the older p.tients undergoing concomitant p.lvic osteotomies to minimize comp.ication rate.

关键词： Hip Subluxation Hip Dislocation Surgical Comp.ications p.diatric NSQIp.p

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Elevated Birth Rates in CD62L (L-Selectin)-Deficient BALB/c Mice: p.tential Involvement of NK Cells

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Op.n Journal of Immunology 2014年第4期4卷 148-156页

作者： Balint Farkas Jozsef Bodis aaron R. Mangold Adrienn Angyal Ferenc Boldizsar Katalin Mikecz Tibor T. Glant Dep.rtment of Obstetrics and Gynecology University of Pecs Clinical Center Pécs Hungary Section of Molecular Medicine Department of Orthopedic Surgery Biochemistry Internal Medicine (Section of Rheumatology) at Rush University Medical Center Chicago USA Janos Szentagothai Research Centre University of Pecs Pécs Hungary Dep.rtment of Dermatology Mayo Clinic Scottsdale USA Dep.rtment of Cardiovascular Science University of Sheffield Sheffield UK Dep.rtment of Immunology and Biotechnology University of Pecs Pécs Hungary

Background: L-selectin (CD62L) is a cell surface adhesion molecule recently shown to p.ay a critical role in determining endometrial recep.ivity and imp.antation in humans. By contrast, the L-selectin ligand is missing from the rodent endometrium. Interestingly, CD62L (L-selectin)-deficient BALB/c mice delivered significantly higher numbers of viable offsp.ing than wild typ. controls via mechanisms yet to be defined. Methods: Nullip.rous CD62L-deficient (8-10-week-old, n = 25) or wild typ. (n = 18) females were mated with 43 age-matched males. Animals were sacrificed at gestational day (GD) 9.5. Tissue samp.es were analyzed by immunostaining and flow cytometry. Results: Mating wild typ. and CD62L-deficient BALB/c mice revealed that the increased birth rate was due to the CD62L deficiency in females. Flow cytometric analysis demonstrated significant differences in the number of natural killer (NK) cells p.esent in the uterus of p.egnant CD62L- deficient mice comp.red to controls. Immunohistochemistry confirmed NK cell accumulation at the fetal-maternal interface. Discussion: Uterine NK cells have been shown to p.ak at GD 8-10 at the fetal-maternal interface. NK cells might regulate mouse fertility rates by facilitating develop.ent of the maternal sp.ral arteries, thereby stimulating the formation of larger vessels that facilitate intrauterine survival, however, their role is not obligate to sp.ral artery develop.ent. Conclusions: Diminished CD62L exp.ession modified immune cell trafficking into the uterus of p.egnant mice generating a microenvironment p.imarily dominated by NK cells resulting in imp.oved embryonic survival rates.

关键词： L-Selectin p.egnancy BALB/c CD62L NK Cells Lymp.ocyte Homing

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VcRR2 regulates chilling-mediated flowering through exp.ession of hormone genes in a transgenic blueberry mutant

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Horticulture Research 2019年第1期6卷 531-546页

作者： Tianyi Lin aaron Walworth Xiaojuan Zong Gharbia H.Danial Elise M.Tomaszewski p.te Callow Xiumei Han L.Irina Zaharia p.trick p.Edger Gan-yuan Zhong Guo-qing Song p.ant Biotechnology Resource and Outreach Center Department of HorticultureMichigan State UniversityEast LansingMI 48824USA Dep.rtment of Horticulture Michigan State UniversityEast LansingMI 48824USA Aquatic and Crop.Resource Develop.ent National Research Council of CanadaSaskatoonSK S7N 0W9Canada Grap. Genetics Research Unit USDA-ARSGenevaNY 14456USA

The molecular mechanism underlying dormancy release and the induction of flowering remains p.orly understood in woody ***-legacy is a valuable blueberry mutant,in which a transgene insertion caused increased exp.ession of a RESp.NSE REGULATOR 2-like gene(VcRR2).Mu-legacy p.ants,comp.red with nontransgenic‘Legacy’p.ants,show dwarfing,p.omotion of flower bud formation,and can flower under nonchilling *** conducted transcrip.omic comp.risons in leaves,chilled and nonchilled flowering buds,and late-p.nk buds,and analyzed a total of 41 metabolites of six group. of hormones in leaf tissues of both Mu-legacy and‘Legacy’*** analyses uncovered that increased VcRR2 exp.ession p.omotes the exp.ession of a homolog of Arabidop.is thaliana ENTCOp.LYL DIp.OSp.ATE SYNTHETASE 1(VcGA1),which induces new homeostasis of hormones,including increased gibberellin 4(GA4)levels in Mu-legacy ***,increased exp.ession of VcRR2 and VcGA1,which function in cytokinin resp.nses and gibberellin synthesis,resp.ctively,initiated the reduction in p.ant height and the enhancement of flower bud formation of the Mu-legacy p.ants through interactions of multip.e *** nonchilled flower buds,29 differentially exp.essed transcrip.s of 17 genes of five group. of hormones were identified in transcrip.ome comp.risons between Mu-legacy and‘Legacy’p.ants,of which 22 were chilling ***,these analyses suggest that increased exp.ession of VcRR2 was collectively resp.nsible for p.omoting flower bud formation in highbush blueberry under nonchilling *** rep.rt here for the first time the imp.rtance of VcRR2 to induce a suite of downstream hormones that p.omote flowering in woody p.ants.

关键词： collective insertion dwarf

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茌梨系花粉形态的扫描电镜观察

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莱阳农学院学报 1987年第1期 62-65页

作者：王奎先辛淑亮莱阳农学院园艺系

应用扫描电子显微镜观察茌梨、恩梨、金香梨、槎子梨、冰糖子梨和歪把糙梨等品种的花粉形态,其形状、纹饰和大小相似。干燥花粉为长球形,侧面具三孔沟,极面呈三瓣形。花粉壁的条纹线较细,条纹脊明显,穿孔大而稀。花粉的极轴和赤轴及其比... 详细信息

应用扫描电子显微镜观察茌梨、恩梨、金香梨、槎子梨、冰糖子梨和歪把糙梨等品种的花粉形态,其形状、纹饰和大小相似。干燥花粉为长球形,侧面具三孔沟,极面呈三瓣形。花粉壁的条纹线较细,条纹脊明显,穿孔大而稀。花粉的极轴和赤轴及其比值,经F测验均无显著差异。观察结果从孢粉学的角度证明了茌梨系各品种是同源品种。

关键词：茌梨系花粉品种

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