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Journal of Advanced Ceramics 2016年第3期5卷 262-268页

作者： hiromichi aono Yuhi YAMANO Takashi NAOHARA Yoshiteru ITAGAKI Tsunehiro MAEHARA Hideyuki HIRAZAWA Graduate School of Science and Engineering Ehime University Matsuyama 790-8577 Japan National Institute of Technology Niihama College Niihama 792-8580 Japan

Composite powder material of the Y3Fe5O12–nSiC system was synthesized by a reverse coprecipitation method to study its heat generation property in an AC magnetic field. For Y3Fe5O12 (n = 0), the maximum heat generation ability of 0.45 W·g−1 in an AC magnetic field (370 kHz, 1.77 kA·m−1) was obtained for the sample calcined at 1100 °C. The SiC addition helped to suppress the particle growth for Y3Fe5O12 at the calcination temperature. The heat generation ability was improved by the addition of the SiC powder, and the maximum value of 0.93 W·g−1 was obtained for the n = 0.3 sample calcined at 1250 °C. The heat generation ability and the hysteresis loss value were proportional to the cube of the magnetic field (H 3). The heat generation ability (W·g−1) of the Y3Fe5O12–0.3SiC sample calcined at 1250 °C could be expressed by the equation 4.5×10−4 · f · H 3 using the frequency f (kHz) and the magnetic field H (kA·m−1).

关键词： magnetic materials composite material Y 3 Fe 5 O 12 SiC heat generation ability AC magnetic field

Improvement of Heat Generation Ability in AC Magnetic Field and Magnetic Properties for Spinel Type MgFe_2O_4 Ferrite by Cu Substitution and Beads Milling

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Journal of Iron and Steel Research(International) 2012年第S1期19卷 596-599页

作者： Hideyuki HIRAZAWA hiromichi aono Takashi Naohara Tsunehiro MAEHARA Yuji WATANABE Department of Environmental Materials Engineering Niihama National College of TechnologyNiihama 792858 0 EhimeJapan Graduate School of Science and Engineering Ehime UniversityMatsuyama 790857 7Ehime Japan Department of Organ Regenerative Surgery Ehime UniversityToon 791029 5EhimeJapan

Mg_(1-X)Cu_XFe_2O_4 type spinel ferrite was prepared by solid reaction method in order to discuss the heat generation ability in AC magnetic *** cubic type ferrite structure was obtained for X=0-0.6 samples calcined at 1200℃,and the mixture phase of cubic and tetragonal structures were obtained for X=0.7,0.8 samples from XRD result. The highest lattice parameter and highest hysteresis loss value were also shown at X=0.6 sample,the crystal distortion was increased with increase the Cu^(2+)substitution in cubic type ferrite *** sized nano Mg_(0.4)Cu_(0.6)Fe_2O_4 powder was prepared by physical milling method using beads *** highest heat generation in the AC magnetic field was obtained for the 6 h milled samples using 0.1mm *** Cu^(2+)substitution for MgFe_2O_4 ferrite and the beads milling were very effective for the improvement of their heat generation ability in AC magnetic field.

关键词： heat generation ability AC magnetic field spinel ferrite beads milling

Heat Generation Properties in AC Magnetic Field for Ferrimagnetic R_3Fe_5O_(12) (R=Y,Sm,Gd,Dy,Ho,Er) Powder Materials Synthesized by Reverse Coprecipitation Method

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Journal of Iron and Steel Research(International) 2012年第S1期19卷 600-603页

作者： Tadahiko NISHIMORI Takashi NAOHARA Tsunehiro MAEHARA Hideyuki HIRAZAWA hiromichi aono Graduate School of Science and Engineering Ehime UniversityMatsuyama 790-8577Japan Department of Environmental Materials Engineering Niihama National College of Technology

R_3Fe_5O_(12)(R=Y,Sm,Gd,Dy,Ho,Er)powders synthesized by a reverse coprecipitation method were investigated for their heat generation ability in an AC magnetic *** heat generation ability in an AC magnetic field was strongly influenced by the particle size,i.e.,calcination temperature of the *** highest heat generation ability was obtained for the Y_3Fe_5O_(12)sample calcined at 1100 ℃.The heat generation ability(W.g^(-1))can be estimated using a 3.6× 10^(-4)fH^3(frequency(flkHz)and the magnetic field(H/kA·m^(-1)))for the Y_3Fe_5O_(12)sample calcined at 1100 ℃.

关键词： heat generation AC magnetic field ferrite powder

High-Frequency Induction Heating of Needle-Shaped Mg-Ferrite for Ablation Therapy of Human Cancer

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Journal of Iron and Steel Research(International) 2012年第S2期19卷 735-738页

作者： NAOHARA Takashi aono hiromichi MAEHARA Tsunehiro HIRAZAWA Hideyuki MATSUTOMO Shinya WATANABE Yuji Graduate School of Science and Engineering Ehime University Department of Environmental Materials Engineering Niihama National College of Technology Department of Electronic Control Engineering Niihama National College of Technology Department of Surgery Graduate School of MedicineEhime University

For application as a novel ablation therapy of human cancer,the heating property of a needle-shaped Mg-ferrite prepared by a sintering technique was studied in a high-frequency induction field at 370 *** inserted into cylindrical clay,the increase in temperature(Δ7)was 31.2℃ for the specimen with a 1.5 mm diameter,while the 1.0mm diameter specimen exhibited a ΔT value of 15.7℃ after the induction time of *** ΔT exhibited a high value of 57.9℃ during the simultaneous insertion of 3 1.5mm diameter *** the computer simulation images, the relatively lower magnetic flux density and concurrent neghgibly low current density were observed from the surface to the internal regions,being different from the behavior of a ferromagnetic Ni-rod with the same size.

关键词： high-frequency induction heating cancer therapy ablation treatment eddy current loss residual loss

Positive Effect of Transcranial Direct Current Stimulation on Visual Verbal Working Memory in Patients with Attention-Deficit/Hyperactivity Disorder

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Open Journal of Psychiatry 2024年第4期14卷 334-346页

作者： Tomoko Uchida Daisuke Matsuzawa Tadashi Shiohama Katsunori Fujii Akihiro Shiina Masamitsu Naka Katsuo Sugita Eiji Shimizu Naoki Shimojo hiromichi Hamada Department of Pediatrics Graduate School of Medicine Chiba University Chiba Japan Research Center for Child Mental Development Chiba University Chiba Japan Division of Medical Care and Treatment Center for Forensic Mental Health Chiba University Chiba Japan Department of Cognitive Behavioral Physiology Graduate School of Medicine Chiba University Chiba Japan

Background: Working memory is an executive function that plays an important role in many aspects of daily life, and its impairment in patients with attention-deficit/hyperactivity disorder (ADHD) affects quality of life. The dorsolateral prefrontal cortex (DLPFC) has been a good target site for transcranial direct current stimulation (tDCS) due to its intense involvement in working memory. In our 2018 study, tDCS improved visual-verbal working memory in healthy subjects. Objective: This study examines the effects of tDCS on ADHD patients, particularly on verbal working memory. Methods: We conducted an experiment involving verbal working memory of two modalities, visual and auditory, and a sustained attention task that could affect working memory in 9 ADHD patients. Active or sham tDCS was applied to the left DLPFC in a single-blind crossover design. Results: tDCS significantly improved the accuracy of visual-verbal working memory. In contrast, tDCS did not affect auditory-verbal working memory and sustained attention. Conclusion: tDCS to the left DLPFC improved visual-verbal working memory in ADHD patients, with important implications for potential ADHD treatments.

关键词： Working Memory Attention-Deficit/Hyperactivity Disorder Dorsolateral Prefrontal Cortex Transcranial Direct Current Stimulation

Neoadjuvant therapy for resectable pancreatic cancers

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 583-585页

作者： Yosuke Inoue hiromichi Ito Yu Takahashi Division of Hepato-Biliary-Pancreatic Surgery Cancer Institute HospitalJapanese Foundation for Cancer ResearchTokyoJapan

Pancreatic cancer(PC)is a potentially systemic disease with more diverse biology than generally *** present,surgical resection is the only curative therapy available for patients with PC,and its indications have long been discussed based on anatomical resectability.A recent consensus recommends neoadjuvant therapy(NAT)for anatomically borderline resectable(BR)cancers(1)as well as induction therapy for unresectable locally advanced(UR-LA)or metastatic(UR-M)cancers.

关键词： cancers therapy curative

Morphology and gene expression of sex‐determining region Y‐box 9 and runt‐related transcription factor 2 in centrifugally compressed cell collagen‐combined constructs (C^(6))

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Biosurface and Biotribology 2023年第3期9卷 78-83页

作者： Xu Ye Masashi Yamazaki Wataru Ando Norimasa Nakamura hiromichi Fujie Faculty of System Design Tokyo Metropolitan UniversityTokyoJapan Research Center for Medicine‐Engineering Collaboration TokyoJapan Department of Orthopaedic Surgery Kansai Rosai HospitalAmagasakiJapan Department of Orthopaedic Surgery Osaka University Graduate School of MedicineSuitaJapan Institute for Medical Science in Sports Osaka Health Science UniversityOsakaJapan Center for Advanced Medical Engineering and Informatics Osaka UniversitySuitaJapan

The authors previously developed a scaffold‐free tissue‐engineered construct(TEC)from mesenchymal stem cells(MSCs).Although the TEC exhibited even cell distribution and was successfully applied for cartilage repair in animal models,it is unsuitable for relatively large‐scale cartilage defects due to its small *** solve the problem,the authors recently developed a novel biomaterial,a centrifugally compressed cell‐collagen combined construct(C^(6))from a mixture of MSCs and atelocollagen,both of which are subjected to *** results of the previous study indicated that C^(6) exhibited high cell viability(70%)and sufficient cell distribution similar to that of the *** the present study,the morphology and gene expression of C^(6) were *** ex-amination indicated that C6 is six times thicker(approximately 1 mm)than the TEC after a 7‐day *** C^(6) remained unchanged in scale with increased cell density after a 21‐day *** electron microscopic observation indicated that C^(6) exhibited interconnected and porous microstructures,while the TEC had close‐knit *** transcriptase‐polymerase chain reaction analysis indicated that the expression of sex‐determining region Y‐box 9 and runt‐related transcription factor 2 was significantly higher in C^(6) than that in TEC.

关键词： biomaterials cartilage microstructures

Rikkunshito increases peripheral incretin-hormone levels in humans and rats

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World Journal of Methodology 2024年第1期14卷 102-113页

作者： Hiroshi Kono Shinji Furuya Hidenori Akaike Katsutoshi Shoda Yoshihiko Kawaguchi Hidetake Amemiya hiromichi Kawaida Daisuke Ichikawa The First Department of Surgery University of YamanashiChuoYamanashi 409-3898Japan

BACKGROUND It was reported that rikkunshito(TJ-43)improved the cisplatin-induced decreases in the active form of ghrelin in plasma;however,other effects on gastrointestinal hormones have not been *** To investigate the effects of TJ-43 on peripheral levels of incretin hormones,including gastric inhibitory polypeptide(GIP)and glucagon-like polypeptide-1(GLP-1),in humans and *** Patients were divided into two groups,namely patients who received TJ-43 immediately following surgery[TJ-43(+)group]and those who received TJ-43 on postoperative day 21[TJ-43(-)group],and the plasma levels of active GIP and active GLP-1 were *** animal experiments,rats were treated with TJ-43[rat(r)TJ-43(+)group]or without[rTJ-43(−)group]by gavage for 4 wk,and the plasma active GIP and active GLP-1 levels were *** expression of incretin hormones in the gastrointestinal tract and insulin in the pancreas were investigated by ***,the cyclic adenosine monophosphate activities were assessed in pancreatic tissues from rats treated with or without TJ-43 in vivo,and the blood glucose levels and plasma insulin levels were measured in rats treated with or without TJ-43 in oral glucose tolerance *** In humans,the active incretin hormone levels increased,and values were significantly greater in the TJ-43(+)group compared those in the TJ-43(-)*** rats,the plasma active incretin levels significantly increased in the rTJ-43(+)group compared with those in the rTJ-43(-)*** and GLP-1 expressions were enhanced by TJ-43 ***,plasma insulin levels increased and blood glucose levels were blunted in the rTJ-43(+)*** The results show that TJ-43 may be beneficial for patients who undergo pancreatic surgery.

关键词： Incretin hormone Japanese traditional herbal medicine Gastric inhibitory polypeptide Glucagon-like polypeptide-1 Islet cells Insulin

Carbon nanotube-dependent synthesis of armchair graphene nanoribbons

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Nano Research 2022年第3期15卷 1709-1714页

作者： Yifan Zhang Kecheng Cao Takeshi Saito hiromichi Kataura Hans Kuzmany Thomas Pichler Ute Kaiser Guowei Yang Lei Shi State Key Laboratory of Optoelectronic Materials and Technologies Nanotechnology Research CenterGuangzhou Key Laboratory of Flexible Electronic Materials and Wearable DevicesSchool of Materials Science and EngineeringSun Yat-sen UniversityGuangzhou 510275China Central Facility for Electron Microscopy Electron Microscopy Group of Materials ScienceUlm UniversityUlm 89081Germany School of Physical Science and Technology Shanghai Tech UniversityShanghai 201210China Nanomaterials Research Institute National Institute of Advanced Industrial Science and TechnologyTsukuba 305-8565Japan Faculty of Physics University of ViennaVienna 1090-AAustria

Sub-nanometer armchair graphene nanoribbons(GNRs)with moderate band gap have great potential towards novel *** can be synthesized in the confined tubular space of single-walled carbon nanotubes(SWCNTs),in which precursor molecules have been specifically designed to form the GNRs with certain width and ***,it is still unexplored how the diameter and metallicity of SWCNTs influence the synthesis of the ***,we applied a series of SWCNTs with different average diameters to study the diameter-dependent synthesis of *** using Raman spectroscopy and transmission electron microscopy,we found that the width of the GNRs can be tailored by the diameter of the ***,the SWCNTs with average diameter of 1.3 nm produced 6 and 7 armchair GNRs with the highest yield,which can be well explained by considering the width of the GNRs and van der Waals radius of hydrogen and carbon *** addition,semiconducting and metallic SWCNTs produced GNRs with different yields,which could attribute to different diameter distributions and density of *** results enable the possibility of a high-yield production of certain armchair graphene nanoribbons in large scale,which would benefit future applications as semiconductor with sub-nanometer in width.

关键词： armchair graphene nanoribbons single-walled carbon nanotubes Raman spectroscopy diameter dependence metallicity dependence

Evaluation of microstructure and creep damage in high-Cr ferritic steel welds

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Acta Metallurgica Sinica(English Letters) 2011年第3期24卷 225-234页

作者： Masaaki TABUCHI hiromichi HONGO National Institute for Materials Science

11Cr-0.4Mo-2W-CuVNb steel （ASME Gr.122） is used for boiler components in ultra- supercritical （USC） thermal power plants. The creep strength of high-Cr steel welds decreases due to the formation of Type IV creep damage in the heat-affected zone （HAZ） during long-term use at high temperatures. In the present study, the processes and mechanisms of Type Ⅳ creep damage were elucidated by investigating the long-term creep strength, microstructure and damage behavior of Gr.122 steel welds. Creep tests using thick welded joints were interrupted at several time steps, and the initiation, evolution and distribution of creep damage were measured. It was found that the formation and growth of creep damage was suppressed during the steady- state stage; creep voids formed at 0.5 of life, and coalesced to form a crack after 0.9 of life. Type IV creep damage was mostly observed in the area about 30% below the surface of the plate. Differences in creep damage behavior between Gr.122 and Gr.91 steel welds were examined. Experimental creep damage distribution was compared with computed versions using the finite element method and damage mechanics.

关键词： Gr.122 steel Welded joint Creep void Type Ⅳ damage Finite element method Damage mechanics