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New Chiral Norbornenesultam as the Chiral Auxiliary in Asymmetric Alkylation

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厦门大学学报（自然科学版） 1999年第S1期38卷 211-211页

作者： w.H.Chan a.w.m.lee Department of Chemistry HongKong Baptist UniversityKowloon Tong HongKongChina

Superplasticity of fine-grained mg-10Li alloy prepared by severe plastic deformation and understanding its deformation mechanisms

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Journal of magnesium and Alloys 2024年第1期12卷 316-331页

作者： H.T.Jeong S.w.lee w.J.Kim Department of materials Science and Engineering Hongik UniversityMapo-guSangsu-dong 72-1Seoul 121-791Republic of Korea

The superplastic behavior and associated deformation mechanisms of a fine-grained mg-10.1 Li-0.8Al-0.6Zn alloy(LAZ1011)with a grain size of 3.2μm,primarily composed of the BCCβphase and a small amount of the HCPαphase,were examined in a temperature range of 473 K to 623 *** microstructural refinement of this alloy was achieved by employing high-ratio differential speed *** best superplasticity was achieved at 523 K and at strain rates of 10^(-4)-5×10^(-4)s^(-1),where tensile elongations of 550±600%were *** the heating and holding stage of the tensile samples prior to tensile loading,a significant increase in grain size was observed at temperatures above 573 ***,it was important to consider this effect when analyzing and understanding the superplastic deformation behavior and *** the investigated strain rate range,the superplastic flow at low strain rates was governed by lattice diffusion-controlled grain boundary sliding,while at high strain rates,lattice diffusion-controlled dislocation climb creep was the rate-controlling deformation *** was concluded that solute drag creep is unlikely to *** the late stages of deformation at 523 K,it was observed that grain boundary sliding led to the agglomeration of theαphase,resulting in significant strain *** mechanism maps were constructed forβ-mg-Li alloys in the form of 2D and 3D formats as a function of strain rate,stress,temperature,and grain size,using the constitutive equations for various deformation mechanisms derived based on the data of the current tests.

关键词： magnesium-lithium alloy Superplasticity Severe plastic deformation Grain size Grain growth

A parsimonious Bayesian predictive model for forecasting new reported cases of west Nile disease

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Infectious Disease modelling 2024年第4期9卷 1175-1197页

作者： Saman Hosseini lee w.Cohnstaedt John m.Humphreys Caterina Scoglio Department of Electrical and Computer Engineering Kansas State UniversityManhattanKSUSA Foreign Arthropod-Borne Animal Diseases Research Unit National Bio-and Agro-defense Facility USDA ARSManhattanKSUSA Foreign Animal Disease Research Unit National Bio-and Agro-defense FacilityUSDA ARSManhattanKSUSA

Upon researching predictive models related towest Nile virus disease,it is discovered that there are numerous parameters and extensive information in most models,thus contributing to unnecessary *** challenge frequently encountered is the lead time,which refers to the period for which predictions are made and often is too *** paper addresses these issues by introducing a parsimonious method based on ICC curves,offering a logistic distribution model derived from the vector-borne SEIR *** existing models relying on diverse environmental data,our approach exclusively utilizes historical and present infected human cases(number of new cases).with a yearlong lead time,the predictions extend throughout the 12 months,gaining precision as new data *** conditions are derived to minimize Bayesian loss,enhancing predictive *** construct a Bayesian forecasting probability density function using carefully selected prior *** these functions,we predict monthspecific infections nationwide,rigorously evaluating accuracy with probabilistic ***,HPD credible intervals at 90%,95%,and 99%levels is *** assessment is conducted for HPD intervals,measuring the proportion of intervals that does not include actual reported cases for 2020e2022.

关键词： west nile virus ICC curve Bayesian model Logistic distribution HPD credible interval

Nonuniform Dependence on the Initial Data for Solutions of Conservation Laws

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Communications on Applied mathematics and Computation 2024年第1期6卷 489-500页

作者： John m.Holmes Barbara lee Keyfitz Department of mathematics The Ohio State UniversityColumbusOH43210USA

In this paper,we study systems of conservation laws in one space *** prove that for classical solutions in Sobolev spaces H^(s),with s>3/2,the data-to-solution map is not uniformly *** results apply to all nonlinear s... 详细信息

关键词： Conservation laws Data-to-solution map Nonuniform dependence

Imprinting at the KBTBD6 locus involves species-specific m ternal methylation and monoallelic expression in livestock animals

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Journal of Animal Science and Biotechnology 2024年第1期15卷 127-145页

作者： Jinsoo Ahn In-Sul Hwang mi-Ryung Park Seongsoo Hwang Kichoon lee Department of Animal Sciences The Ohio State UniversityColumbusOH 43210USA Animal Biotechnology Division Rural Development AdministrationNational Institute of Animal ScienceJeonbuk 55365Republic of Korea Columbia Center for Translational Immunology Columbia University Irving Medical CenterColumbia UniversityNew YorkNY 10032USA Animal welfare Research Team National Institute of Animal ScienceRDA1500Kongjwipatjwi‑roJeollabuk‑do 55365Republic of Korea

Background The primary differentially methylated regions(DmRs) which are maternally hypermethylated serve as imprinting control regions(ICRs) that drive monoallelic gene expression, and these ICRs have been investigated due to their implications in mammalian development. Although a subset of genes has been identified as imprinted, in-depth comparative approach needs to be developed for identification of species-specific imprinted genes. Here, we examined DNA methylation status and allelic expression at the KBTBD6 locus across species and tissues and explored potential mechanisms of *** Using whole-genome bisulfite sequencing and RNA-sequencing on parthenogenetic and normal porcine embryos, we identified a maternally hypermethylated DmR between the embryos at the KBTBD6 promoter Cp G island and paternal monoallelic expression of KBTBD6. Also, in analyzed domesticated mammals but not in humans, non-human primates and mice, the KBTBD6 promoter Cp G islands were methylated in oocytes and/or allelically methyl-ated in tissues, and monoallelic KBTBD6 expression was observed, indicating livestock-specific imprinting. Further analysis revealed that these Cp G islands were embedded within transcripts in porcine and bovine oocytes which coexisted with an active transcription mark and DNA methylation, implying the presence of transcription-dependent *** In this study, our comparative approach revealed an imprinted expression of the KBTBD6 gene in domesticated mammals, but not in humans, non-human primates, and mice which implicates species-specific evolution of genomic imprinting.

关键词： Differentially methylated region Domesticated mammal Imprinting KBTBD6 Parthenogenetic

Developing a two-decadal time-record of rice field maps using Landsat-derived multi-index image collections with a random forest classifier:A Google Earth Engine based approach

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Information Processing in Agriculture 2024年第2期11卷 260-275页

作者： w.Ashane m.Fernando I.P.Senanayake Department of Nano Science Technology Wayamba University of Sri LankaKuliyapitiya 60200Sri Lanka Dchoolf Engineing CllegeoEngineeringSience and EnionmentThe UniversyewcastleCallaghanW2Austraia

Historic maps showing the temporal distribution of rice fields are important for precision agriculture,irrigation optimisation,forecasting crop yields,land use management and formulating ***,mapping rice felds using traditional ground surveys is impractical when high cost,time and labour requirements are considered,and the availability of such detailed records is *** satellite remote sensing appears to be a viable solution,conventional segmentation and classification methods with spectral bands are often unable to contrast the distinct characteristics between rice fields and other vegetation *** this end,we explored a novel,Google Earth Engine(GEE)based multiindex random forest(RF)classification approach to map rice fields over two *** images from 2000 to 2020 of two Sri Lankan rice cultivation districts were extracted from GEE and a multi-index RF classification algorithm was applied to distinguish the rice *** results showed above 80%accuracy for both training and validation,when compared against high spatial resolution Google Earth *** essence,multi-index sampling and RF together synergised the compelling classifcation accuracy by effectively capturing vegetation,water(ponding)and soil characteristics unique to the rice felds using a single-click *** maps developed in this study were further compared against the mODIS land cover type product(mCD12Q1)and the corresponding superior statistics on rice fields demonstrated the robustness of the proposed *** work seeking effective index combinations is recommended,and this approach can potentially be extended to other crop analyses elsewhere.

关键词： Google Earth Engine(GEE) Image classification Random forest mapping rice fields Time series analysis Vegetation index

Strengthening mechanisms analysis and tailoring of bimodal grain structures for enhanced strength in CoCrFemnNi high-entropy alloys

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Rare metals 2024年第8期43卷 3893-3903页

作者： Jaesoung lee Seulgi Kim Taehyun Kwon Young II Kim Suyeon Kim Sung Ho Song Bin lee Dongju lee Department of Urban Energyand Environmental EngineeringChungbuk National UniversityCheongju 28644Republic of Korea Division of Advanced materials Engineering Kongju National UniversityChungnam 330-717Republic of Korea Department of Advanced materials Engineering for Information and Electronics Integrated-Education Institute for Frontier Science and Technology(BK21 Four)Kyung Hee UniversityYongin17104Republic of Korea

The CoCrFemnNi high-entropy alloys(HEAs)with a(face-centered cubic) FCC structure has garnered considerable attention for its exceptional ductility and strain hardening ***,its yield strength is insufficient for structural *** this study,strengthening mechanisms in these HEAs were investigated to gain insight into the mechanical properties according to alloy powder ***,we present a novel approach to achieve both high strength and high ductility through the creation of a bimodal structure consisting of both coarse and fine grains via gas atomization and spark plasma sintering processes.A bimodally structured HEA prepared with a mass ratio of 2:8 between coarse particles(75-106 μm) and fine particles(≤25 μm)yielded optimal results,with a strength of 491.95 mPa and elongation of 19.64%.This strength value represents an~41% increase compared with the sample that displayed a fine single microstructure(347.08 mPa for yield strength).The strength enhancement was attributed to the prevention of plastic deformation initiation from the fine particles during *** innovative approach to the creation of HEAs with bimodal structures shows promise for various applications,such as structural components that require a combination of high strength and high ductility.

关键词： High-entropy alloys CrCoFemoNi Bimodal Gas atomization mechanical properties

Food intolerance and the few-foods(or oligoantigenic)diet in children with attention-deficit hyperactivity disorder

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Food Science and Human wellness 2024年第4期13卷 1729-1738页

作者： Klaus w.Lange Andreas Reissmann Yukiko Nakamura Katharina m.Lange Faculty of Human Sciences University of RegensburgRegensburg 93040Germany Department of Psychology University of BathBath BA27AYUnited Kingdom

The hypothesis that some children with attention-deficit hyperactivity disorder(ADHD)may show sensitivity or allergic reactions to various food items has led to the development of the the few-foods(or oligoantigenic)*** rationale of the diet is to eliminate certain foods from the diet in order to exclude potential allergens contained either naturally in food or in artificial ingredients with allergenic *** oligoantigenic diet attempts to identify individual foods to which a person might be ***,ADHD symptoms are monitored while multiple foods are excluded from the ***,if symptoms remit,foods are re-introduced,while observing the individual for the return of *** advantage of the oligoantigenic diet is that it can be tailored to the individual.A growing body of evidence suggests that behavioral symptoms of subgroups of children with ADHD may benefit from the elimination of certain *** effect sizes of an oligoantigenic diet regarding improvement of ADHD symptoms have been found to be medium to *** evidence suggests that the investigation of the role of food hypersensitivities in ADHD is a promising avenue worthy of further *** large-scale,randomized controlled studies including assessment of long-term outcome are therefore warranted.

关键词： Attention-deficit hyperactivity disorder Food intolerance Few-foods diet Etiology Treatment

Prevalence and intensity of urinary schistosomiasis and soil-transmitted helminths among women of reproductive age in mwaluphamba,Kwale

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Asian Pacific Journal of Tropical medicine 2024年第2期17卷 71-83页

作者： Samuel m.Ngui Joseph m.mwangangi Joachim Richter Josephine w.Ngunjiri Department of Biological Sciences University of EmbuKenya medical Entomology Kenya Medical Research Institute(KEMRI)Center for Geographic Medicine Research Coast KilifiKenya Institute of International Health Global Health CenterCharitéUniversity MedicineBerlinCorporate Member of Free University and Humboldt University and Berlin Institute of HealthBerlinGermany Swiss Tropical and Public Health Institute BaselSwitzerland Tropical and Infectious Diseases Department of Biological sciencesUniversity of EmbuKenya

Objective:To assess the epidemiology of urinary schistosomiasis and soil-transmitted helminthiasis among women of reproductive age in mwaluphamba,Kwale County,***:A community-based cross-sectional study design was employed to randomly sample 422 women of reproductive age(15-m four villages in mwaluphamba *** specimens were collected and examined using the Kato-Katz method,while filtration technique was used to analyze urine ***’sociodemographic details were obtained using a standardized ***:Urinary schistosomiasis prevalence was at 4.7%(20/422,95%CI 2.8%-6.9%)while the prevalence of soil-transmitted helminthiasis infection was 4.5%(19/422,95%CI 2.6%-6.7%).The infection intensities of urinary schistosomiasis among the study participants ranged from 1 to 120 eggs/10 mL of urine with median egg count of 18.45 eggs/10 *** patients were diagnosed with light infection,of 56.16 egg/gram and 48.48 egg/gram for Trichuris trichiura and hookworms,*** without latrines had 15.7 times higher risk of having urinary schistosomiasis compared to those with a ***,use of surface water(aOR=1.0,95%CI 0.2-1.4,P=0.010)and crossing the river to go to a place(aOR=1.1,95%CI 0.3-1.6,P=0.009)were statistically significant risk factors for getting urinary *** bivariable regression analysis,defecating around the water source(OR=4.3,95%CI 1.5-12.9)had a statistically significant association with the prevalence of soil-transmitted helminthiasis(P=0.008).Conclusions:This study has given an insight on the prevalence and intensity of urinary schistosomiasis and soil-transmitted helminthiasis in mwaluphamba location that form a basis for strengthening the control and elimination programmes for these neglected tropical diseases.

关键词： Urinary schistosomiasis Prevalence Soiltransmitted helminths mwaluphamba