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Contrast Normalization Strategies in Brain Tumor Imaging:From Preprocessing to Classification

Computer Modeling in Engineering & Sciences 2024年第8期140卷 1539-1562页

作者： Samar M.Alqhtani Toufique A.Soomro Faisal Bin Ubaid Ahmed Ali Muhammad irfan Abdullah A.Asiri Department of Information Systems College of Computer Science and Information SystemsNajran UniversityNajran61441Saudi Arabia Department of Electronic Engineering The University of LarkanoLarkanaSindh75660Pakistan Computer Science Department Sukkur IBA UniversitySukkurSindh65200Pakistan Eletrical Engineering Department Sukkur IBA UniversitySukkurSindh65200Pakistan Electrical Engineering Department College of EngineeringNajran UniversityNajran61441Saudi Arabia radiological Sciences Department College of Applied Medical SciencesNajran UniversityNajran61441Saudi Arabia

Cancer-related to the nervous system and brain tumors is a leading cause of mortality in various *** resonance imaging(MrI)and computed tomography(CT)are utilized to capture brain *** plays a crucial role in the diagnosis of brain tumors and the examination of other brain ***,manual assessment of MrI images by radiologists or experts is performed to identify brain tumors and abnormalities in the early stages for timely ***,early diagnosis of brain tumors is intricate,necessitating the use of computerized *** research introduces an innovative approach for the automated segmentation of brain tumors and a framework for classifying different regions of brain *** proposed methods consist of a pipeline with several stages:preprocessing of brain images with noise removal based on Wiener Filtering,enhancing the brain using Principal Component Analysis(PCA)to obtain well-enhanced images,and then segmenting the region of interest using the Fuzzy C-Means(FCM)clustering technique in the third *** final step involves classification using the Support Vector Machine(SVM)*** classifier is applied to various types of brain tumors,such as meningioma and pituitary tumors,utilizing the Contrast-Enhanced Magnetic resonance Imaging(CE-MrI)*** proposed method demonstrates significantly improved contrast and validates the effectiveness of the classification framework,achieving an average sensitivity of 0.974,specificity of 0.976,accuracy of 0.979,and a Dice Score(DSC)of ***,this method exhibits a shorter processing time of 0.44 s compared to existing *** performance of this method emphasizes its significance when compared to state-of-the-art methods in terms of sensitivity,specificity,accuracy,and *** enhance the method further in the future,it is feasible to standardize the approach by incorporating a set of classifiers to increase the robustness of the brain classi

关键词： Brain tumor magnetic resonance imaging principal component analysis fuzzy c-clustering support vector machine

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Divergent consequences of bio-resources on morphological plasticity and biochemical responses in early-stage leguminous species:Sustainable productivity approaches

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Geoscience Frontiers 2024年第3期15卷 312-321页

作者： Taimoor Hassan Farooq Muhammad Farrakh Nawaz Muhammad Qasid Awais Shakoor irfan Ahmad Sadaf Gul Khuram Shahzad Xiaoyong Chen Bangor College China A Joint Unit of Bangor University and Central South University of Forestry and TechnologyChangsha 410004China Institute of Environmental Studies University of KarachiKarachi 75270Pakistan Department of Forestry and range Management University of Agriculture FaisalabadPakistan Hawkesbury Institute for the Environment Western Sydney UniversityPenrithNSW 2751Australia Department of Botany University of KarachiKarachi 75270Pakistan Institute of Geographic Sciences and Natural resources research Chinese Academy of SciencesChaoyang DistrictBeijing 100101China College of Arts and Sciences Governors State UniversityUniversity ParkIL 60484USA

Inorganic resources can be detrimental to the environment when *** comparison,organic resources help balance the soil’s carbon and nitrogen(C/N)ratio,enhance soil fertility and benefit ecological *** climate crises,rapid urbanization,and fast population growth are causing many natural forests to be converted to agricultural and industrial lands to fulfill ever-increasing food and developmental *** of different bio-resources becomes necessary for sustainable productivity of available *** study explores the effects of various organic amendments on the growth,morpho-physiological and biochemical attributes of three leguminous tree species:Dalbergia sissoo,Vachellia nilotica,and Acacia ampliceps,concerning sustainable ***-year-old healthy,disease-free,and homogenous seedlings were used as study material in a greenhouse pot *** organic amendments,i.e.,compost(CMP),cow dung(CD),poultry manure(PM),and biochar(BC),along with a control(CK)treatment,were *** showed that all the organic amendments performed significantly better(Produced the most significant results,followed by BC application,while PM influence was the *** all treatments and species,the maximum values of root length,root biomass,chlorophyll content,carotenoids,catalase,and total phenolic content were recorded under the CD *** for plant height and collar diameter,no big differences were observed between CD and BC(P=0.054).While comparing species,*** growth was significantly enhanced under organic amendments,followed by *** and comparative results of studied parameters conclude that CD and BC were the most effective organic amendments,which greatly improved the growth of experimental leguminous tree species;this makes these two biofertilizers a powerful tool for sustainable agricultural *** study contributes toward an enhanced understanding of plant’

关键词： Bio-fertilizers Crop productivity Ecological sustainability Nitrogen fixation Organic cultivation Physiological responses

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Phytoconstituents Profiling of Indigenous Herbal Drugs and Its in vitro Microbial,in Silico Biological Examination against Severe Acute respiratory Syndrome Coronavirus 2

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World Journal of Traditional Chinese Medicine 2024年第1期10卷 121-136页

作者： T.H.Mohamed Ahadu Shareef MMohamed Divan Masood irfan Navabshan MSaiyad Musthafa Department of Chemistry The New College(Autonomous)Affiliated to the University of MadrasChennaiTamil NaduIndia School of Computer Applications B.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil NaduIndia Crescent School of Pharmacy B.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil NaduIndia Department of Zoology The New College(Autonomous)Affiliated to the University of MadrasChennaiTamil NaduIndia

Background:Habb-E-Shifa,Hamdard Sualin,and Hamdard Joshanda traditional herbal medicines may promote host resistance against infection by bacteria,viruses,and fungi which are easily accessible at inexpensive with no *** herbal medicines are used to cure sore throat,cough,fever,lung cancer,and asthma patients in developing South Asian *** traditional herbal medicines acted a crucial role in the prevention and control of coronavirus disease 2019(COVID-19).Aims and Objectives:This research article aimed at conducting phytochemistry,antimicrobial activity,COVID-19 docking and some spectroscopic(Infrared,Ultraviolet,13C-Nuclear Magnetic resonance(13C-NMr),1H-NMr,and Mass Spectra)characterizations of the polyherbal drugs were carried ***,In-vitro and In-silico analyses were performed to measure activity against *** Performance-Liquid Chromatography(HPLC),Gas Chromatography-Mass Spectrometry(GC-MS),antimicrobial,and docking studies were carried *** preliminary phytochemical assay and bioactive compounds were screened using HPLC and *** study is an attempt to assess the promising effects of selected polyherbal indigenous drugs such as Habb-E-Shifa,Hamdard Sualin,and Hamdard Joshanda phytoconstituents against the severe acute respiratory syndrome coronavirus-2(SArS-Co V-2).Materials and Methods:The extract of the selected polyherbal formulations showed high-to-moderate preventive effects on the growth inhibition in the pathogenic bacterium,namely Streptococcus oralis,Staphylococcus aureus,Propionibacterium acnes,Pseudomonas aeruginosa,Escherichia coli,and Proteus vulgaris,and three fungal Candida albicans,Aspergillus fumigatus,and Aspergillus *** docking study evaluates the pharmacological activity of bioactive chemical compounds with SArS-Co V-2 NSP5(PDB ID:7nxh)and SArS-Co V-2 Omicron spike protein with human angiotensin-converting enzyme 2(ACE-2)(PDB ID:7wk6).results:In this study,for the first time,we at

关键词： Antimicrobial herbal drug Omicron and coronavirus disease 2019 phytochemicals spectroscopic

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Securing Cloud-Encrypted Data:Detecting ransomware-as-a-Service(raaS)Attacks through Deep Learning Ensemble

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Computers, Materials & Continua 2024年第4期79卷 857-873页

作者： Amardeep Singh Hamad Ali Abosaq Saad Arif Zohaib Mushtaq Muhammad irfan Ghulam Abbas Arshad Ali Alanoud Al Mazroa School of Computer Information Sciences University of CumberlandsWilliamsburgKentucky40769USA Computer Science Department College of Computer Science and Information SystemsNajran UniversityNajran61441Saudi Arabia Department of Mechanical Engineering College of EngineeringKing Faisal UniversityAl-Ahsa31982Saudi Arabia Department of Electrical Electronics and Computer SystemsCollege of Engineering and TechnologyUniversity of SargodhaSargodha40100Pakistan Electrical Engineering Department College of EngineeringNajran UniversityNajran61441Saudi Arabia Department of Electrical Engineering The University of LahoreLahore54000Pakistan Faculty of Computer and Information Systems Islamic University of MadinahMadinah42351Saudi Arabia Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia

Data security assurance is crucial due to the increasing prevalence of cloud computing and its widespread use across different industries,especially in light of the growing number of cybersecurity threats.A major and everpresent threat is ransomware-as-a-Service(raaS)assaults,which enable even individuals with minimal technical knowledge to conduct ransomware *** study provides a new approach for raaS attack detection which uses an ensemble of deep learning *** this purpose,the network intrusion detection dataset“UNSWNB15”from the Intelligent Security Group of the University of New South Wales,Australia is *** the initial phase,the rectified linear unit-,scaled exponential linear unit-,and exponential linear unit-based three separate Multi-Layer Perceptron(MLP)models are ***,using the combined predictive power of these three MLPs,the ransoDetect Fusion ensemble model is introduced in the suggested *** proposed ensemble technique outperforms previous studieswith impressive performance metrics results,including 98.79%accuracy and recall,98.85%precision,and 98.80%*** empirical results of this study validate the ensemble model’s ability to improve cybersecurity defenses by showing that it outperforms individual *** expanding the field of cybersecurity strategy,this research highlights the significance of combined deep learning models in strengthening intrusion detection systems against sophisticated cyber threats.

关键词： Cloud encryption raaS ensemble threat detection deep learning cybersecurity

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An Artificial Intelligence-Based Framework for Fruits Disease recognition Using Deep Learning

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Computer Systems Science & Engineering 2024年第2期48卷 529-554页

作者： irfan Haider Muhammad Attique Khan Muhammad Nazir Taerang Kim Jae-Hyuk Cha Department of Computer Science HITEC UniversityTaxila47080Pakistan Department of Computer Science Hanyang UniversitySeoulKorea

Fruit infections have an impact on both the yield and the quality of the *** a result,an automated recognition system for fruit leaf diseases is *** artificial intelligence(AI)applications,especially in agriculture,deep learning shows promising disease detection and classification *** recent AI-based techniques have a few challenges for fruit disease recognition,such as low-resolution images,small datasets for learning models,and irrelevant feature *** work proposed a new fruit leaf leaf leaf disease recognition framework using deep learning features and improved pathfinder *** fruit types have been employed in this work for the validation process,such as apple,grape,and *** the first step,a noisy dataset is prepared by employing the original images to learn the designed framework *** EfficientNet-B0 deep model is fine-tuned on the next step and trained separately on the original and noisy *** that,features are fused using a serial concatenation approach that is later optimized in the next step using an improved Path Finder Algorithm(PFA).This algorithm aims to select the best features based on the fitness score and ignore redundant *** selected features are finally classified using machine learning classifiers such as Medium Neural Network,Wide Neural Network,and Support Vector *** experimental process was conducted on each fruit dataset separately and obtained an accuracy of 100%,99.7%,99.7%,and 93.4%for apple,grape,Citrus fruit,and citrus plant leaves,respectively.A detailed analysis is conducted and also compared with the recent techniques,and the proposed framework shows improved accuracy.

关键词： Fruit disease contrast enhancement augmentation deep learning fusion feature selection classification

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Juvenile hormone induces reproduction via mir-1175-3p in the red imported fire ant, Solenopsis invicta

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Insect Science 2024年第2期31卷 371-386页

作者： Jie Chen Ziying Guan Yunjie Ma Qingxing Shi Ting Chen Muhammad irfan WarisLihua Lyu Lihua Lyu Yongyue Lu Guojun Qi Institute of Plant Protection Guangdong Academy of Agricultural SciencesKey Laboratory of Green Prevention and Control on Fruits and Vegetables in South China Ministry of Agriculture and Rural AffairsGuangdong Provincial Key Laboratory of High Technology for Plant ProtectionGuangzhouChina Department of Entomology College of Plant ProtectionSouth China Agricultural UniversityGuangzhouChina

Juvenile hormone(JH)acts in the regulation of caste differentiation between queens and workers(i.e.,with or without reproductive capacity)during vitellin synthesis and oogenesis in social ***,the regulatory mechanisms have not yet been ***,we identified a highly expressed microrNA(mirNA),mir-1175-3p,in the red imported fire ant,Solenopsis *** found that mir-1175-3p is prominently present in the fat bodies and ovaries of ***,mir-1175-3p interacts with its target gene,broad-complex core(Br-C),in the fat *** utilizing mir-1175-3p agomir,we successfully suppressed the expression of the Br-C protein in queens,resulting in reduced vitellogenin expression,fewer eggs,and poorly developed ***,decreasing mir-1175-3p levels led to the increased expression of Br-C and vitellogenin in workers,triggering the“re-development”of the ***,when queens were fed with JH,the expression of mir-1175-3p decreased,whereas the expression of vitellogenin-2 and vitellogenin-3 ***,the suppression of fertility in queens caused by treatment with agomir mir-1175-3p was completely rescued by the increased vitellogenin expression induced by being fed with *** results suggest the critical role of mir-1175-3p in JH-regulated reproduction,shedding light on the molecular mechanism underlying mirNA-mediated fecundity in social insects and providing a novel strategy for managing ***.

关键词： juvenile hormone mir-1175-3p red imported fire ant reproduction social insects vitellogenin

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Isolation and Characterization of Cellulose Nanofiber(CNF)from Kenaf(Hibiscus cannabinus)Bast through the Chemo-Mechanical Process

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Journal of renewable Materials 2024年第6期12卷 1057-1069页

作者： rudi Dungani Mohammad irfan Bakshi Tsabita Zahra Hanifa Mustika Dewi Firda A.Syamani Melbi Mahardika Widya Fatriasari School of Life Sciences and Technology Institut Teknologi BandungBandung40132Indonesia research Center for Biomass and Bioproducts National Research and Innovation Agency(BRIN)Cibinong16911Indonesia

The present work emphasizes the isolation of cellulose nanofiber(CNF)from the kenaf(Hibiscus cannabinus)bast through a chemo-mechanical *** order to develop high CNF yield with superior properties of CNF for improving compatibility in varied applications this method is *** fiber purification involved pulping and bleaching treatments,whereas mechanical treatment was performed by grinding and high-pressure *** kraft pulping as a delignification method followed by bleaching has successfully removed almost 99%lignin in the fiber with high pulp yield and delignification *** morphology of the fibers was characterized by scanning electron microscopy,which showed a smooth surface,fiber bundles,gel-shaped nanofiber,and an average size of 94.05 nm with 69%of CNF in 34–100 nm *** chemo-mechanical process exhibited a more crystalline nature in CNF than pulp *** low zeta potential values exhibit the distribution of fibrils and colloidal suspension stability without any further agglomeration.A lower concentration of CNF is less stable exhibiting the product ***,the chemo-mechanical process for the isolation of CNF(Hibiscus cannabinus)from kenaf involves sustainable,low-cost,non-toxic,and cheap alternatives than other traditional methods.

关键词： Kenaf bast fiber kraft delignification and bleaching ultrafine grinder chemo-mechanical properties CNF

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Volatile organic compounds for the detection of hepatocellular carcinoma—A scoping review

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iLIVEr 2024年第1期3卷 45-51页

作者： Sayed Metwaly Alicja Psica Opeyemi Sogaolu irfan Ahmed Ashis Mukhopadhya Mirela Delibegovic Mohamed Bekheit Division of Internal Medicine Aberdeen Royal InfirmaryNHS GrampianScotlandAberdeenAB252ZDUnited Kingdom Aberdeen Cardiovascular and Diabetes Centre School of MedicineMedical Sciences and NutritionUniversity of AberdeenForesterhill Health CampusAberdeenAB252ZDUnited Kingdom Department of Critical Care Medicine University of CalgaryAlberta T2N 2T9Canada Department of General Surgery Aberdeen Royal InfirmaryNHS GrampianScotlandAberdeen AB252ZDUnited Kingdom Pakistan Kidney and Liver Institute and research Centre Lahore 54000Pakistan Hépatica Centre of Integrated HPB CareElite HospitalAlexandria 21325Egypt

Hepatocellular carcinoma(HCC)is an increasingly common and the second leading cause of cancer mortality worldwide with a 5-year survival rate about 12%.Less than 20%of HCC patients are eligible to curative treatment owing to the late ***,there is a need for a readily accessible,early screening *** scoping review critically appraises and synthesizes the current published knowledge about the use of exhaled volatile organic compounds(VOCs)as a potential noninvasive means for HCC detection aiming to advance this nascent field.A systematic electronic search was *** search strategy included all studies published until the 24th of March 2023 using a combination of relevant *** search yielded 9 publications using the Preferred reporting Items for Systematic reviews and Meta-analyses *** of the studies described in vitro experiments,and seven clinical studies were conducted on small groups of ***,42 headspace gases were analyzed in the in vitro ***,the clinical studies included 420 HCC patients and 630 *** studies reported potential role for a combination of VOCs in the diagnosis of ***,there is lack of *** there appears to be promise in VOCs research associated with HCC,there is no single volatile biomarker in exhaled breath attributed to HCC and data from extracted studies indicates a lack of *** multicentre population studies are required to verify the existence of VOCs linked to HCC.

关键词： Hepatocellular carcinoma Volatile organic compounds Metabolomics

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Multi-site Passivation of ZnO Metal Oxides via Biomolecules for Efficient and Highly Stable Organic Solar Cells

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Chinese Journal of Chemistry 2024年第14期42卷 1582-1592页

作者： irfan Ismail Maria Khalil Xiaomei Gao Xingze Chen Muhammad Jawad rong Huang Zhiyun Li Emmanuel Acheampong Tsiwah Wei-shi Li Qun Luo Chang-Qi Ma i-Lab&Printable Electronics research Center Suzhou Institute of Nano-Tech and Nano-Bionics(SINANO)Chinese Academy of Sciences(CAS)SuzhouJiangsu215123 China University of Chinese Academy of Sciences(UCAS) Beijing100040 China School of Nano-Tech and Nano-Bionics University of Science and Technology of China(USTC)HefeiAnhui230027 China Shanghai Institute of Organic Chemistry(SIOC) Chinese Academy of Sciences(CAS)Shanghai200032 China Vacuum Interconnected Nanotech Workstation(Nano-X) SuzhouJiangsu215123 China

ZnO nanoparticles(nps)among metal oxide(MOs)are proven to be essential electron transporting layers(ETLs)applied in organic solar cells(OSCs).However,intrinsic defects,interfacial charge recombination,and catalytic behavior towards the active layer restrict the applications of ZnO nps for efficient and long-term stable *** commonly available biomolecule cytidine 5'-monophosphate(CMP-OH)with phosphonic acid,its salt cytidine 5'-monophosphate disodium salt(CMP-ONa)with a phosphate group as an anchoring group and conjugated terminal functional in both analogous molecules provide carrier transfer bridge at bottom interface of the active *** theoretical investigations and characterizations have discovered the multi-site coordination of CMP-OH towards acceptor molecules and ZnO *** dual-side alignment of CMP analogous molecules hinders interfacial charge recombination and enhances charge transfer potential at ***,PM6:L8-BO-based OSCs with modified ETL obtain 18.13%efficiency,12%higher than that of unmodified *** higher efficiency,CMP-OH-based OSC devices illustrate remarkably improved thermal stability for 500 h at 85℃with 72%of initial PCE and operation stability for 2000 h with 90.1%of initial *** work reveals the passivation mechanism of multi-anchoring groups towards MOs and single-functional groups towards the active layer to optimize the interface for efficient and highly stable OSCs.

关键词： Organic solar cells Nanoparticles Nucleotides Interfacial interactions Surface chemistry Multi-site passivation

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Knowledge, attitudes, and practices regarding Covid-19 and their relationship with Covid-19 booster vaccination status among women with infertility

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Asian pacific Journal of reproduction 2024年第2期13卷 68-75页

作者： Gita Pratama Mila Maidarti Kanadi Sumapradja Achmad Kemal Harzif Natasha Talya Kevin Ezekia irfan Arieqal Hatta Ampri reproductive Immunoendocrinology Division Department of Obstetrics and GynecologyFaculty of Medicine Universitas Indonesia-dr.Cipto Mangunkusumo General HospitalJakartaIndonesia Yasmin IVF Clinic dr.Cipto Mangunkusumo General Hospital JakartaIndonesia Human reproduction Infertilityand Family Planning ClusterIndonesia Reproductive Medicine Research and Training CenterFaculty of MedicineUniversitas IndonesiaJakarta 10430Indonesia Department of Obstetrics and Gynecology Faculty of Medicine Universitas Indonesia-dr.Cipto Mangunkusumo General HospitalJakartaIndonesia

Objective:To elucidate the relationship among knowledge,attitudes,and practices regarding Covid-19 and their relationship with booster vaccination status among women with ***:This questionnaire-based cross-sectional study was performed online and offline among women with infertility who visited an infertility clinic in Jakarta,*** assessed the patient’s knowledge,attitudes,and practices regarding Covid-19 and their relationship with booster vaccination status and sociodemographic ***:A total of 178 subjects participated in this study,and most participants(92.6%)had received booster Covid-19 *** the questionnaire,74.2%had good knowledge,and 99.4%had good attitudes regarding Covid-19;however,only 57.9%of patients had good practices.A weak positive correlation existed between knowledge and attitudes(r=0.11,P=0.13)and a moderate negative correlation between attitudes and practices(r=-0.44,P=0.56).Participants’knowledge about vaccines and infertility was correlated with booster vaccination status(P=0.04).Academic background(P=0.01)and attitudes(P=0.01)were also correlated with booster vaccination *** significant determinants of hesitance of receiving Covid-19 booster vaccines were high school education or below(Or=0.08,95%CI 0.02-0.36)and poor practices(Or=0.21,95%CI 0.05-0.95).Conclusions:The majority of the participants had received the Covid-19 booster vaccine and had good knowledge and attitudes but poor practices regarding *** participants had poor knowledge about the relationship between infertility and the Covid-19 *** general population should be more informed and reminded about practices to prevent Covid-19 and the relationship between vaccination and fertility to increase the number of people who receive Covid-19 booster vaccines.

关键词： Covid-19 Booster vaccine Infertility Knowledge Attitude Practice Human reproduction Pandemic

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