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Nationwide questionnaire survey on pediatric pancreatic tumors in Japan

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World Journal of Gastrointestinal Oncology 2024年第10期16卷 4166-4176页

作者： Satoshi Makita Hiroo Uchida Motohiro kano Naonori Kawakubo Hiromu Miyake Akihiro Yoneda Tatsuro Tajiri Koji Fukumoto Department of Pediatric Surgery Nagoya University Graduate School of MedicineNagoya 466-8550Japan Department of Pediatric Surgery National Center for Child Health and DevelopmentTokyo 157-8535Japan Department of Pediatric Surgery Reproductive and Developmental MedicineFaculty of Medical SciencesKyushu UniversityFukuoka 819-0395Japan Department of Pediatric Surgery Shizuoka Children’s HospitalShizuoka 420-8660Japan

BACKGROUND Pediatric pancreatic tumors are rare and account for<0.1%of all childhood *** primary treatment for pancreatic tumors is surgical ***,because of the lack of knowledge regarding pediatric pancreatic tumors,no comprehensive treatment plans for pediatric pancreatic tumors have been *** To compared the clinical features,treatment methods,and prognosis of pediatric pancreatic tumors in Japan with those in other *** Questionnaires were sent to 213 pediatric surgical units in *** tumors that were not surgically treated were excluded from the *** primary survey investigated the number of patients aged 0-18 years who underwent pancreatic tumor surgery and the type of tumors managed during the 22-year study period(from January 1,2000 to December 31,2021)by post *** secondary survey assessed the clinical images,treatment methods,and tumor outcomes via *** The primary survey enrolled 228 *** the secondary survey,213 patients were eventually *** most common type of pancreatic tumor was solid pseudopapillary neoplasm(SPN)[n=164(77.0%)],followed by pancreatoblastoma[n=16(7.5%)],pancreatic endocrine tumor[n=14(6.6%)],non-epithelial tumor[n=9(4.2%)],pancreatic tumor[n=7(3.3%)],and metastatic pancreatic tumor[n=3(1.4%)].Overall,123(57.7%)patients underwent distal pancreatectomy,of whom 49 underwent laparoscopic ***-four(20.7%)patients underwent enucleation,of whom eight underwent laparoscopic ***-two(15.0%)patients underwent pancreaticoduodenectomy,of whom one underwent laparoscopic *** patients with SPN,including those with distant metastases and recurrent disease,*** SPN was more common in Japan than in other *** of the histological type,resection is the most effective treatment for pediatric pancreatic tumors.

关键词： Pancreatic tumors Pediatric Nationwide survey Solid pseudopapillary tumors Pancreatoblastoma

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嘉兴种子艺术中心

现代装饰 2024年第2期 118-125页

作者：无 Eichi kano(摄影) 朱清言(摄影) B.L.U.E.建筑设计事务所不详

“种子艺术中心”位于嘉兴市南湖区,距离市中心东侧10公里,处在城市与自然的过渡边界。周围一半是农场与公园,一半是住宅与商业街,不同方位面向不同的景观与氛围,形成了多元、生动的场所感。四周道路交汇,人流聚集于此,是整个片区最具... 详细信息

“种子艺术中心”位于嘉兴市南湖区,距离市中心东侧10公里,处在城市与自然的过渡边界。周围一半是农场与公园,一半是住宅与商业街,不同方位面向不同的景观与氛围,形成了多元、生动的场所感。四周道路交汇,人流聚集于此,是整个片区最具活力的核心点位。项目定位为地产配套设施,近期作为附近社区的展示中心与零售空间,未来则活用为周边共享的邻里中心。

关键词：邻里中心场所感嘉兴市南湖区配套设施商业街展示中心项目定位零售空间

评估数字相位对比乳腺X线摄影系统的乳腺X线片计算机辅助检测病变的能力

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国际医学放射学杂志 2010年第1期 98-98页

作者： T.Tanaka N.Nitta S.Ohta T.Kobayashi a.kano K.Tsuchiya 朱慧玲 Department of Radiology Shiga University of Medical ScienceTsukinowa-choSetaOtsuShiga 520-2192Japan

评价计算机辅助检测(CAD)系统对数字相位对比乳腺X线摄影(PCM)系统摄片图像中检测微小钙化和肿块的能力,PCM系统是以相位对比和25μm像素的高分辨率乳腺X线摄影提供的清晰图像为特征。从大约3500例乳腺X线片中收集50例正常的和50例异常... 详细信息

评价计算机辅助检测(CAD)系统对数字相位对比乳腺X线摄影(PCM)系统摄片图像中检测微小钙化和肿块的能力,PCM系统是以相位对比和25μm像素的高分辨率乳腺X线摄影提供的清晰图像为特征。从大约3500例乳腺X线片中收集50例正常的和50例异常的乳腺X线摄影打印成胶片并在观片灯上阅片。7名有

关键词：辅助检测相位对比乳腺乳房计算机

The role of protein phosphorylation in the regulation of class switch recombination

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BIOCELL 2020年第4期44卷 545-558页

作者： kano TANABE RYUTARO KAJIHARA Department of Medical Technology Faculty of Health ScienceKumamoto Health Science UniversityKumamoto861-5598Japan Department of Biomedical Laboratory Sciences Faculty of Life SciencesKumamoto UniversityKumamoto862-0976Japan Center for Immunotherapy Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA

Antibody is an important part of adaptive immune system and is produced only by B *** are five main classes(IgM,IgD,IgG,IgA,IgE)and some subclasses in *** and IgD are produced by mature naïve B *** the other hand,IgG,IgA and IgE are produced by activated antigen-specific B cells via class switch recombination(CSR).CSR is the irreversible DNA rearrangement from upstream to downstream classes in immunoglobulin heavy chain ***-stimulations of CD40 ligand(CD40L)and cytokines are required for induction of CSR by activating several transcription *** signal transduction pathways involve many protein *** or dephosphorylation of cellular protein is an important kind of post-translational protein modification in intracellular signal *** the fact,more than one third of the intracellular proteins are said to be transiently phosphorylated in human.A protein kinase is an enzyme that catalyzes the addition of phosphate to substrate ***,a protein phosphatase catalyzes the removal of phosphate from the *** review focuses on the mechanism of CSR controlled by protein phosphorylation and *** provide the role of protein kinase and phosphatase in the regulation of class switch recombination.

关键词： Antibody Kinase Phosphatase Signal Transduction

Application of DEM modified with enlarged particle model to simulation of bead motion in a bead mill

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Particuology 2014年第3期12卷 103-108页

作者： Yasuhiro Yamamoto Rikio Soda Junya.kano Fumio Saito Mikuni Color Ltd. 101 KokubunjiMikunino-choHimejiHyogo 671-0234Japan Institute of Multidisciplinary Research for Advanced Materials Tohoku University2-1-1 KatahiraAoba-kuSendai 980-8577Japan

We applied the discrete element method （DEM） of simulation modified by an enlarged particle model to simulate bead motion in a large bead mill. The stainless-steel bead mill has inner diameter of 102 mm and mill length of 198 mm. The bead diameter and filling ratio were fixed respectively at 0.5 mm and 85%. The agitator rotational speed was changed from 1863 to 3261 rpm. The bead motion was monitored experimentally using a high-speed video camera through a transparent mill body. For the simulation, enlarged particle sizes were set as 3-6 mm in diameter. With the DEM modified by the enlarged particle model, the motion of enlarged particles in a mill was *** velocity data of the simulated enlarged particles were compared with those obtained in the experiment. The simulated velocity of the enlarged particles depends on the virtual frictional coefficient in the DEM model. The optimized value of the virtual frictional coefficient can be determined by considering the accumulated mean value. Results show that the velocity of the enlarged particles simulated increases with an increase in the optimum virtual frictional coefficient, but the simulated velocity agrees well with that determined experimentally by optimizing the virtual frictional coefficient in the simulation. The computing time in the simulation decreases with increased particle size.

关键词： Discrete element simulation Bead mill Bead motion Enlarged particle model

A combination of tides and nontidal variations in ocean bottom pressure may generate interannual slip fluctuations in the transition zone along a subduction plate interface

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Geodesy and Geodynamics 2023年第1期14卷 43-51页

作者： Yoshiyuki Tanaka Hiromu Sakaue Masayuki kano Suguru Yabe Department of Earth and Planetary Science The University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-0033Japan Graduate School of Science Tohoku University6-3Aramaki-aza-aobaAoba-kuSendai980-8578Japan Geological Survey of Japan National Institute of Advanced Industrial Science and Technology(AIST)Tsukuba Central 71-1-1 HigashiTsukubaIbaraki 305-8567Japan

The tidal triggering of earthquakes has been studied for many *** discovery of slow earthquakes in the early 2000s,including slow slip,has urged scientists to investigate the tidal responses of these earthquakes due to their sensitivity to weak stress *** studies have shown that slow earthquakes correlate with diurnal and semidiurnal tides and seasonal variations in surface loads more clearly than ordinary ***,little is known about long-term responses to external *** this paper,based on a widely accepted frictional law for faults,a mechanism is proposed by which nontidal variations in ocean bottom pressure,when combined with tides,pro mote the occurrence of slow *** slow earthquakes accompany a slip on the plate interface,this mechanism allows one to estimate slip modulations.A one-degree-of-freedom slip model is constructed and applied to Ise Bay in the Tonankai region of southwestern Japan,where large-scale ocean mass redistributions have *** model calculated with parameters determined from the observation of tectonic tremors is quantitatively consistent with the slip during 1997-2013 inferred from GNSS data,suggesting that the decrease in the sea-level change in approximately 2006 could cause the accele ration of a slip observed after *** result implies that the decreases in sea level in approximately 1996 and 2014 could also cause subsequent slip *** three slip acceleration periods temporally coincide with the increases in background seismicity in a shallower portion of the plate *** changes in seismicity are common to shallow earthquakes in the Tokai area,and a similar model can reproduce *** studies are expected to reveal causality between shallow earthquakes and long-term slip fluctuations based on modeling that considers changes in the frictional property along the plate interface.

关键词： Tides Ocean bottom pressure Slow earthquake Seismicity Kuroshio current

A[k,k+1]-factor containing given Hamiltonian cycle

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Science China Mathematics 1998年第9期41卷 933-938页

作者：蔡茂诚李彦君 M.kano 1. Institute of Systems Science Chinese Academy of Sciences 100080 Beijing China 2. Department of Computer and Information Sciences Ibaraki University Hitachi 316 Japan

Letk?2 be an integer and let G be a graph of ordern with minimum degree at leastk, n?8k -16 for evenn and n?6k - 13 for oddn. If the degree sum of each pair of nonadjacent vertices of G is at least n, then for any giv... 详细信息

关键词： graph connected factor Hamiltonian cycle.

Star-Like Factors with Large Components

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Journal of the Operations Research Society of China 2015年第1期3卷 81-88页

作者： Yao Zhang Gui-Ying Yan Mikio kano Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China Department of Computer and Information Sciences Ibaraki UniversityHitachiIbaraki 316-8511Japan

A star-factor of a graph G is a spanning subgraph of G in which every component is a *** and Saito(Discret Math 312:2005-2008,2012)showed that a graph G satisfying iso(G−S)≤|S|/m for every S⊂V(G)contains a{K1,t:m≤t≤2m}-factor,where iso(G−S)denotes the number of isolated vertices in G−*** they conjectured that a graph G satisfying iso(G−S)≤|S|/m for every S⊂V(G)actually contains a({K1,t:m≤t≤2m−1}∪{K2m+1})-*** this paper,we show that this conjecture is true.

关键词： Star-factor Component Isolated vertex

Super-low friction of ta-C coating in presence of oleic acid

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Friction 2014年第2期2卷 156-163页

作者： Makoto kano Jean Michel MARTIN Kentaro YOSHIDA Maria Isabel DE BARROS BOUCHET Division of Mechanical&Material Engineering Kanagawa Industrial Technology Center705-1 Shimo-ImaizumiEbinaKanagawaJapan LTDS Ecole Centrale de Lyon 69380EcullyFrance

Friction tests have been carried out on bearing steel friction pairs coated with a-C:H and ta-C under lubricated conditions with 1-hexadecene and pure oleic acid,*** results show that ta-C leads to the super-low regime with oleic acid(friction coefficient below 0.01)and that a-C:H is quite well lubricated by *** analyses by coupling X-ray photoelectron spectroscopy(XPS)and secondary ion mass spectrometry(SIMS)have been carried out in the case of oleic acid with ta-C and a-C:H *** show that tribochemical reactions have *** groups terminate the ta-C surface whereas a-C:H is covered by a thin tribofilm and is terminated by oleic acid *** superlow regime in the case of ta-C is mainly attributed to the presence of the OH-termination.

关键词： epoxy composite short carbon fiber friction wear