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Application of positron emission tomography/computed tomography in radiation treatment planning for head and neck cancers

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World journal of Radiology 2015年第11期7卷 382-393页

作者： Musaddiq j Awan Farzan Siddiqui David schwartz jiankui Yuan Mitchell Machtay Min Yao Department of Radiation Oncology Case Comprehensive Cancer Center University Hospitals and Case Western Reserve University School of Medicine Department of Radiation Oncology Henry Ford Health System Department of Radiation Oncology University of Texas Southwestern Medical Center

18-fluorodeoxygluocose positron emission tomography/computed tomography(18FDG-PET/CT) provides significant information in multiple settings in the management of head and neck cancers(HNC). This article seeks to define the additional benefit of PET/CT as related to radiation treatment planning for squamous cell carcinomas(SCCs) of the head and neck through a review of relevant literature. By helping further define both primary and nodal volumes, radiation treatment planning can be improved using PET/CT. Special attention is paid to the independent benefit of PET/CT in targeting mucosal primaries as well as in detecting nodal metastases. The utility of PET/CT is also explored for treatment planning in the setting of SCC of unknown primary as PET/CT may help define a mucosal target volume by guiding biopsies for examination under anesthesia thus changing the treatment paradigm and limiting the extent of therapy. Implications of the use of PET/CT for proper target delineation in patients with artifact from dental procedures are discussed and the impact of dental artifact on CT-based PET attenuation correction is assessed. Finally, comment is made upon the role of PET/CT in the high-risk post-operative setting, particularly in the context of radiation dose escalation. Real case examples are used in these settings to elucidate the practical benefits of PET/CT as related to radiation treatment planning in HNCs.

关键词： Head and neck cancer Radiation treatment planning

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Rapid assembly of multilayer microfluidic structures via 3D-printed transfer molding and bonding

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Microsystems & Nanoengineering 2016年第1期2卷 29-37页

作者： Casey C.Glick Mitchell T.Srimongkol Aaron j.schwartz William S.Zhuang joseph C.Lin Roseanne H.Warren Dennis R.Tekell Panitan A.Satamalee Liwei Lin Department of Physics University of CaliforniaBerkeleyCA 94720USA Department of Mechanical Engineering University of CaliforniaBerkeleyCA 94720USA Department of Mechanical Engineering University of UtahSalt Lake CityUT 84112USA

A critical feature of state-of-the-art microfluidic technologies is the ability to fabricate multilayer structures without relying on the expensive equipment and facilities required by soft lithography-defined ***,three-dimensional(3D)printed polymer molds are used to construct multilayer poly(dimethylsiloxane)(PDMS)devices by employing unique molding,bonding,alignment,and rapid assembly ***,a novel single-layer,two-sided molding method is developed to realize two channel levels,non-planar membranes/valves,vertical interconnects(vias)between channel levels,and integrated inlet/outlet ports for fast linkages to external fluidic *** a demonstration,a single-layer membrane microvalve is constructed and tested by applying various gate pressures under parametric variation of source pressure,illustrating a high degree of flow rate *** addition,multilayer structures are fabricated through an intralayer bonding procedure that uses custom 3D-printed stamps to selectively apply uncured liquid PDMS adhesive only to bonding interfaces without clogging fluidic *** integrated alignment marks to accurately position both stamps and individual layers,this technique is demonstrated by rapidly assembling a six-layer microfluidic *** combining the versatility of 3D printing while retaining the favorable mechanical and biological properties of PDMS,this work can potentially open up a new class of manufacturing techniques for multilayer microfluidic systems.

关键词： 3D printing microfluidics PDMS

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A high-performance BCI

A high-performance BCI

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中国神经科学学会第十届全国学术会议

作者： Andrew schwartz U Pittsburgh

Population decoding allows us to extract high-fidelity information about movements that will occur in the near *** multiple movement parameters are encoded simultaneously in the same population of neurons,we have been gradually increasing the degrees of freedom（DOF） that a subject can control through the *** early work showed that 3-dimensions could be controlled in a virtual reality *** then demonstrated control of an anthropomorphic physical device with 4 DOF in a self-feeding ***,monkeys in our laboratory are using this interface to control a 7-DOF arm,wrist and hand to grasp objects in different locations and *** paradigm has been extended to a tetraplegic woman,who has been able to operate a high-performance prosthetic arm and hand to carry out reach and grasp tasks,characteristic of those performed in daily life with up 10-DOF.

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Excessive participation in on-line internet action games by two American teenagers: Case report, description of extent of overuse, and adverse consequences

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Open journal of Pediatrics 2013年第3期3卷 201-203页

作者： Richard H. schwartz Inova Children’s Hospital Falls Church USA

In the past 15 years, there have been more than 40 articles in the medical literature about excessive participation in on-line internet action games by adolescents and young adults. The following case reports provide detailed information on two boys, ages 16 and 20 years respectively, who are compulsive and enthusiastic internet gamers, to the exclusion of family communication, school activities, academic performance, participation in sports and dating. They have not mastered any of the usual goals of adolescent development.

关键词： Internet Game Addiction Excessive Internet Gaming

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精梳生产中的自动化

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纺织导报 2013年第11期 65-66页

作者： Yvan schwartz 立达

在全球超过50%的市场中都证明了这一点：采用Rieter （立达）精梳系统可获得最佳的成纱质量。立达提供的精梳自动化在提高产量和灵活性方面的情况如何呢？

关键词：精梳系统自动化生产 Rieter 成纱质量立达

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Cardiac tamponade due to group a streptococcal pericarditis in a 10-month-old boy and a review of the literature

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Open journal of Pediatrics 2011年第4期1卷 87-89页

作者： Matthew C. schwartz Matthew j. Gillespie Paul Stephens Brian Fisher 不详

Group A streptococcus (GAS) is a rare cause of purulent pericarditis in pediatric patients as only 7 cases have been reported. We present a 10-month-old boy who developed cardiac tamponade from GAS and was successfull... 详细信息

关键词： Streptococcus Pericarditis Pericardiocentesis Tamponade

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Remaking Shanghai If Shanghai becomes a global financial center by 2020, what does that mean for today？

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China International Business 2009年第7期 55-57页

作者： BRIAN schwartz ISABEL DING

After the State Council＇s announcement last March that Shanghai would be turned into a global financial center by 2020, you could hear a collective sigh of disappointment in Shenzhen and Tianjin, two other cities which were competing for the title of China＇s financial center, and had now lost the opportunity to the Yangtze port city. Hong Kong, the traditional financial center of China, now also has to reposition itself to deal with another nearby city offering many of the same services.

关键词：国际金融中心上海城市竞争港口城市国务院中国

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Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

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四川生理科学杂志 2023年第10期45卷 1848-1848页

作者： Gregory G schwartz From the Division of Cardiology University of Colorado School of Medicine Aurora (G.G.S.) Assistance Publique–Hôpitaux de Paris Hôpital Bichat Paris Diderot University Sorbonne Paris Cité FACT (French Alliance for Cardiovascular Trials) and INSERM Unité 1148 (P.G.S.) and Sanofi (C.H. G.L.) — all in Paris the National Heart and Lung Institute Imperial College Royal Brompton Hospital London (P.G.S.) the State University of New York Downstate School of Public Health Brooklyn (M.S.) and Regeneron Pharmaceuticals Tarrytown (R.P. W.J.S.) — both in New York Brigham and Women’s Hospital Heart and Vascular Center and Harvard Medical School Boston (D.L.B.) the Division of Cardiovascular Disease University of Alabama at Birmingham Birmingham (V.A.B.) Estudios Cardiológicos Latinoamérica Instituto Cardiovascular de Rosario Rosario Argentina (R.D.) Sanofi Bridgewater NJ (J.M.E. A.M. J.-F.T.) the Canadian VIGOUR Centre University of Alberta Edmonton and St. Michael’s Hospital University of Toronto Toronto — both in Canada (S.G.G.) Stanford Center for Clinical Research Department of Medicine Stanford University Stanford CA (R.A.H. K.W.M.) the Department of Cardiology Leiden University Medical Center Leiden the Netherlands (J.W.J.) Duke Clinical Research Institute Duke University Medical Center (K.Q. M.T.R. P.T.) and the Division of Cardiology Department of Medicine Duke University School of Medicine (M.T.R.) Durham NC Green Lane Cardiovascular Services Auckland City Hospital Auckland New Zealand (H.D.W.) and the Department of Medicine III Goethe University Frankfurt am Main Germany (A.M.Z.).

Background:Patients who have had an acute coronary syndrome are at high risk for recurrent ischemic cardiovascular *** sought to determine whether alirocumab,a human monoclonal antibody to proprotein convertase subtilisin-kexin type 9(PCSK9),would improve cardiovascular outcomes after an acute coronary syndrome in patients receiving high-intensity statin therapy.

关键词： cardiovascular acute coronary

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基于元分析揭示全球尺度下反硝化反应器中基质材料对硝态氮去除的显著影响

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Engineering 2023年第2期21卷 214-226,M0008页

作者：范豫川庄杰 Michael Essington Sindhu jagadamma john schwartz jaehoon Lee Biosystems Engineering and Soil Science University of TennesseeKnoxvilleTN 37996USA University of Florida Everglades Research and Education CenterBelle GladeFL 33430USA Center for Environmental Biotechnology University of TennesseeKnoxvilleTN 37996USA Civil and Environmental Engineering University of TennesseeKnoxvilleTN 37996USA

反硝化生物反应器(DNBR)被广泛用于减少农业废水中过量的硝酸盐。其性能取决于基质的物理和化学性质。在以前的研究中,已经对一部分常见基质做了总结。然而,很少有研究尝试确定基质类型在硝酸盐去除中起作用的一般模式。本研究利用从63... 详细信息

反硝化生物反应器(DNBR)被广泛用于减少农业废水中过量的硝酸盐。其性能取决于基质的物理和化学性质。在以前的研究中,已经对一部分常见基质做了总结。然而,很少有研究尝试确定基质类型在硝酸盐去除中起作用的一般模式。本研究利用从63篇同行评审文章中收集的数据总结了41种基质类型,包括219个独立DNBR单元。基质分为四类:(1)天然碳(NC),如木屑;(2)非天然碳(NNC),如可生物降解聚合物[如聚己内酯(PCL)和废品(如纸板)];(3)无机材料(IM),如非碳材料(如氧化铁);(4)复合材料(MM),如上述材料的混合物。通过对硝酸盐去除速率[NRR,氮去除(g·m^(-3)·d^(-1))]和硝酸盐去除效率(NRE,%)的元分析,对这些材料进行比较和评估。本文综合阐述了基质效果(NRR和NRE)、潜在机理、污染交换和成本分析。我们的分析表明,木屑和玉米芯是NC中最具成本效益的基质。对比所有参与研究的基质,我们建议将MM作为最优基质,尤其是具有很大的改进空间的基于木屑和玉米芯的基质。该分析有助于优化DNBR的设计,以满足使用者对环境、经济和实用的需求。

关键词：硝酸盐去除农业废水生物反应器可生物降解聚合物同行评审氮去除成本效益无机材料

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Observational study of a new modular femoral revision system

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World journal of Orthopedics 2020年第3期11卷 167-176页

作者： Karen Dyreborg Michael Mørk Petersen Sidse schwartz Balle Anne Grete Kjersgaard Søren Solgaard Department of Orthopaedic Surgery Herlev-Gentofte Hospital2900 HellerupDenmark Department of Orthopaedic Surgery Rigshospitalet2100 KøbenhavnDenmark Department of Diagnostic Radiology Herlev-Gentofte Hospital2900 HellerupDenmark

BACKGROUND The uncemented ArcosTM Modular Femoral Revision System(ARCOS)is a new comprehensive,press-fit revision *** modular design offers a wide range of possible combinations to accommodate different variations of anatomy and bone *** ARCOS is made by a proximal body and a distal *** probably the only ones worldwide we predominantly use a combination of body and stem which supports proximal fixation and load,since this mimics the concept of the primary total hip arthroplasty with proximal weight-bearing,leading to bone stock preservation and no stress shielding or thigh *** To evaluate the early results after femoral revision in a consecutive series of patients undergoing surgery over 3 *** We included 116 patients in the *** were operated in the period August 2011 to December 2014 and we got a clinical mean observation time of 4(0.5-6)*** and radiographical follow-up included present function of the hip assessed by Harris Hip Score,Oxford Hip Score,and EQ5D(measure of health outcome).Of the 116 patients,17 died in the interim and were consequently included only in the implant survivorship analysis;46 patients attended the follow-up *** In total 6(5%)hips were re-revised due to infection(n=3),fracture(n=2)or subsidence(n=1).No patient was re-revised due to aseptic *** 1-,2-and 5-year probability of implant survival(95%CI)were 97%(93%-100%),97%(93%-100%)and 96%(92%-99%),*** this cohort 95 patients received a combination of a proximal broach and a distal curved and slotted stem(BS),aiming for proximal fixation and load bearing;21 patients received a different *** comparing these two groups the BS-group had a 5-year implant survival probability(95%CI)of 97%(93%-100%)compared with the group of other combinations with a 5-year implant survival probability(95%CI)of 90%(78%-100%)(P=0.3).Our regression analysis showed that periprosthetic fracture as an indication for the ARCO

关键词： Hip prosthesis Arthroplasty Implantation Replacement arthroplasty Total hip replacements Modular femoral stem

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