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Injector Quantum Dot Molecule Infrared Photodetector:A Concept for Efficient Carrier Injection

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Nano-Micro Letters 2011年第2期3卷 121-128页

作者： Thomas gebhard Thomas gebhard Photonics InstituteVienna University of Technology

Quantum dot infrared photodetectors are expected to be a competitive technology at high oper ation temperatures in the long and very long wavelength infrared spectral *** the fact that they already achieved notable success,the performance suffers from the thermionic emission of electrons from the quantum dots at elevated temperatures resulting in a decreasing *** order to provide an efficient carrier injection at high temperatures,quantum dot infrared photodetectors can be separated into two parts:an injection part and a detection part,so that each part can be separately *** order to integrate such functionality into a device,a new class of quantum dot infrared photodetectors using quantum dot molecules will be *** addition to a general discussion simulation results suggest a possibility to realize such a device.

关键词： Quantum dot infrared photodetector Injection Quantum dot molecule High temperature operation Responsivity

Impact of antithrombin Ⅲ on hepatic and intestinal microcirculation in experimental liver cirrhosis and bowel inflammation: An in vivo analysis

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World Journal of Gastroenterology 2005年第32期11卷 4997-5001页

作者： Sasa-Marcel Maksan Zilfi lger Martha Maria.gebhard Jan Schmidt Department of SurgeryUniversity of Mainz Germany Department of SurgeryUniversity of Heidelberg Germany

AIM： To analyze the hepatic and intestinal microcirculation in an animal model of liver cirrhosis and inflammatory bowel disease （IBD） and to characterize bhe anti-inflammatory action of antithrombin Ⅲ （ATⅢ） on leukocyte kinetics and liver damage. METHODS： Hepatic and intestinal microcirculation was investigated by intravital videomicroscopy. Standardized models of experimental chronic liver cirrhosis and bowel inflammation were employed. Animals were divided into four groups （n = 6/group）： controls, animals with cirrhosis, animals with cirrhosis and IBD, animals with cirrhosis and IBD treated with ATIII. RESULTS： Cirrhosis facilitated leukocyte rolling and sticking in hepatic sinusoids （1.91±0.28 sticker/μm vs 0.5±0.5 sticker/μm in controls, P〈0.05）. The effect enhanced in animals with cirrhosis and IBD （5.4±1.65 sticker/μm）, but reversed after ATIII application （3.97±1.04 sticker/μm, P〈0.05）. Mucosal blood flow showed no differences in cirrhotic animals and controls （5.3±0.31 nL/min vs5.4±0.25 nL/min） and was attenuated in animals wibh cirrhosis and IBD significantly （3.49±0.6 nL/min）. This effect was normalized in the treatment group （5.13±0.4 nL/min, P〈0.05）. Enzyme values rose during development of cirrhosis and bowel inflammation, and reduced after ATIII application （P〈0.05）. CONCLUSION： Liver cirrhosis in the presence of IBD leads to a significant reduction in mucosal blood flow and an increase in hepatic leukocyte adherence with consecutive liver injury, which can be prevented by administration of ATⅢ.

关键词： Liver cirrhosis Microcirculation Bowel inflammation Liver Antithrombin Ⅲ

Disturbance of hepatic and intestinal microcirculation in experimental liver cirrhosis

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World Journal of Gastroenterology 2005年第6期11卷 846-849页

作者： Sasa-Marcel Maksan Eduard Ryschich Zilfi (U|¨)lger Martha Maria.gebhard Jan Schmidt Department of Surgery

AIM: To analyze hepatic, mesenteric and mucosal microcirculation and leukocyte-endothelium interaction (LEI) in a rat model with liver ***: Hepatic cirrhosis was induced in Wistar rats by gavage with carbon tetrachloride, and intravital videomicroscopy was performed in liver, mesentery and small intestine mucosa. Special emphasis is given on microcirculatory and morphometric changes during cirrhotic portal ***: LEI was influenced significantly in the cirrhotic liver but not in the gut. Blood flow measurement showed significant differences among liver, main mesenteric vessels and the mucosa. The results of our study indicate that liver cirrhosis leads to alterations in hepatic and mesenteric blood flow but not in mucosal blood ***: The enhanced inflammatory response in hepatic microvessels may be caused by a decrease of antithrombin Ⅲ levels and could be responsible for disturbances of organ pathology.

关键词： Liver cirrhosis Microcirculation Small intestine Liver

SEX,CRIME,AND *** INTERPRETATION SUMERISCHER LITERATURWERKE.BERLEGUNGEN ZU INANA-K UND UKALETUDA

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Journal of Ancient Civilizations 2001年第1期16卷 37-58页

作者： gebhard J.Selz Wien

Mice lacking perforin have improved regeneration of the injured femoral nerve

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Neural Regeneration Research 2022年第8期17卷 1802-1808页

作者： Igor Jakovčevski Monika von Düring David Lutz Maja Vulović Mohammad Hamad gebhard Reiss Eckart Förster Melitta Schachner Institut für Anatomie und Klinische Morphologie Universität Witten/HerdeckeWittenGermany Department of Neuroanatomy and Molecular Brain Research Ruhr University BochumBochumGermany Department of Anatomy Faculty of Medical SciencesUniversity of KragujevacKragujevacSerbia Keck Center for Collaborative Neuroscience and Department of Cell Biology and Neuroscience Rutgers UniversityPiscatawayNJUSA

The role that the immune system plays after injury of the peripheral nervous system is still not completely ***,a natural killer cell-and T-lymphocyte-derived enzyme that mediates cytotoxicity,plays important roles in autoimmune diseases,infections and central nervous system trauma,such as spinal cord *** dissect the roles of this single component of the immune response to injury,we tested regeneration after femoral nerve injury in perforin-deficient(Pfp^(-/-))and wild-type control *** frame motion analysis showed better motor recovery in Pfp^(-/-)mice compared with control mice at 4 and 8 weeks after *** tracing of the motoneuron axons regrown into the motor nerve branch demonstrated more correctly projecting motoneurons in the spinal cord of Pfp^(-/-)mice compared with *** of regrown axons measured by g-ratio was more extensive in Pfp^(-/-)than in wild-type mice in the motor branch of the femoral ***^(-/-)mice displayed more cholinergic synaptic terminals around cell bodies of spinal motoneurons after injury than the injured *** histologically analyzed lymphocyte infiltration 10 days after surgery and found that in Pfp^(-/-)mice the number of lymphocytes in the regenerating nerves was lower than in wild-types,suggesting a closed blood-nerve barrier in Pfp^(-/-)*** conclude that perforin restricts motor recovery after femoral nerve injury owing to decreased survival of motoneurons and reduced myelination.

关键词： blood-nerve barrier femoral nerve injury locomotor recovery lymphocytes myelination NK-cells perforin reinnervation

Hepatosplanchnic circulation in cirrhosis and sepsis

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World Journal of Gastroenterology 2015年第9期21卷 2582-2592页

作者： Meghan Prin Jan Bakker gebhard Wagener Department of Anesthesiology College of Physicians and Surgeons of Columbia UniversityNew YorkNY 10032United States Department of Intensive Care Unit Erasmus University Medical Center3015 GD RotterdamThe Netherlands

Hepatosplanchnic circulation receives almost half of cardiac output and is essential to physiologic *** cirrhosis is estimated to affect up to 1% of populations worldwide,including 1.5% to 3.3% of intensive care unit *** leads to hepatosplanchnic circulatory abnormalities and end-organ *** and cirrhosis result in similar circulatory changes and resultant multi-organ *** review provides an overview of thehepatosplanchnic circulation in the healthy state and in cirrhosis,examines the signaling pathways that may play a role in the physiology of cirrhosis,discusses the physiology common to cirrhosis and sepsis,and reviews important issues in management.

关键词： Liver cirrhosis Sepsis Splanchnic circulation Hepa

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中国企业向纳米比亚的国际技术转让

中国企业向纳米比亚的国际技术转让

作者： gebhard Haipinge Tobias 江西财经大学

学位级别：硕士

跨国公司对东道国的发展有着重要的影响。本文研究了跨国公司是否给发展中国家提供了技术支持和创新溢出。为了实现这一目的,本文研究了跨国公司对于发展中国家的积极影响和消极影响。本文的研究结果,有助于理解跨国公司在纳米比亚的知... 详细信息

跨国公司对东道国的发展有着重要的影响。本文研究了跨国公司是否给发展中国家提供了技术支持和创新溢出。为了实现这一目的,本文研究了跨国公司对于发展中国家的积极影响和消极影响。本文的研究结果,有助于理解跨国公司在纳米比亚的知识溢出效应,而且有可能鼓励纳米比亚政府接纳更多的跨国公司。此外,这也给其他发展中国家带来启示,尤其是非洲的,它们与纳米比亚有着类似的情况。目前的研究还将为进一步研究跨国公司的技术转让和发展对发展中国家的影响提供基础。该项研究主要收集并利用二手数据来进行分析跨国公司的技术转移。本文使用的二手数据主要来自书籍、期刊、公司网站报告、报纸和网站。基于现有数据,本文对问题进行了合理的分析和解释。本文利用一个案例分析来进行有效的研究。尽管各种驱动因素在某种程度上遵守了《气候公约》组织的框架,但纳米比亚的技术转让很小。因此必须作出更多努力,使纳米比亚成为一个技术独立国家,增加其知识和创新的份额,并缩小技术差距和创新赤字。数据结果表明,通过国际分包（外包）进行货物和贸易服务是纳米比亚传播和技术转让的纽带。

关键词：跨国公司技术转让机制

Streptococcal Antibody Probe Crosses the Blood Brain Barrier and Interacts within the Basal Ganglia

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Open Journal of Pathology 2015年第2期5卷 42-49页

作者： Robyn gebhard Courtney Huff Mathew Osborne Lisa Riegle Marie Kelly-Worden Department of Physiology and Health Science Ball State University Muncie USA

Within the brain, the basal ganglia (basal nuclei) regulates wanted movement and inhibits unwanted movement. This area of the brain is intertwined with capillary beds that bring nutrients to the brain and form the blood brain barrier. During disease state, antibodies are increased in circulation and movement of these antibodies into the basal ganglia can occur. Streptococcal infection can lead to the generation of antibodies that have autoimmune activity within the brain. These antibodies have been implicated in neurological disorders. In our laboratory, an in vitro study of a monoclonal mouse antibody generated against the class 1 epitope of the M6 protein has demonstrated binding within the basal ganglia of Lewis rat brains. Here we present an in vivo study using Lewis rats injected with either the streptococcal antibody or an anti-myosin positive control. The interaction and movement of the antibody from blood vessels into the tissues of the basal ganglia was determined through the use of immunofluorescence and fluorescent microscopy and is contrasted with IgG injected and uninjected controls. Our data demonstrates that the streptococcal antibody penetrates the blood brain barrier within 24 hours (as determined by the presence of immunofluorescence outside of blood vessels) and remains significantly elevated above control values even 72 hours after injection (p < 0.05). In contrast, the anti-myosin positive control was not visualized in the interstitial fluid until 48 hours post injection and was no longer significantly above control levels by 72 hours. IgG injected controls did not display movement of antibody into the brain. Therefore, the streptococcal antibody is capable of crossing the blood brain barrier and interacting with tissues of the basal ganglia.

关键词： Blood Brain Barrier Antibodies Basal Ganglia Streptococcus Rat

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加速器二极磁体的应力和磁场分析(英文)

电工电能新技术 2004年第3期23卷 13-17页

作者：王秋良 gebhard Moritz 中国科学院电工研究所北京100080 德国重离子研究中心

在本论文中,我们发展了磁机械耦合的ANSYS分析方法,使用有限元方法研究了加速器二极磁体的应力特性,通过数值模拟,我们研究了超导加速器磁体在磁体装配,冷却和运行磁场为2T时的应力。研究的结果将用于评估超导加速器磁体在建造和运行时... 详细信息

在本论文中,我们发展了磁机械耦合的ANSYS分析方法,使用有限元方法研究了加速器二极磁体的应力特性,通过数值模拟,我们研究了超导加速器磁体在磁体装配,冷却和运行磁场为2T时的应力。研究的结果将用于评估超导加速器磁体在建造和运行时的应力控制。

关键词：二极磁体有限元分析超导加速器