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Evaluation of diagnostic cytology via endoscopic naso-pancreatic drainage for pancreatic tumor

World Journal of Gastrointestinal Endoscopy 2014年第8期6卷 366-372页

作者： Tomoyuki Iwata Katsuya Kitamura Akira Yamamiya Yu ishii Yoshiki Sato Tomohiro Nomoto Akitoshi Ikegami Hitoshi Yoshida Division of Gastroenterology Department of Medicine Showa University School of Medicine Shinagawa-ku Tokyo 142-8666 Japan

AIM: To evaluate the usefulness of cytology of the pancreatic juice obtained via the endoscopic naso-pancreatic drainage tube(ENPD-C).METHODS: ENPD was performed in cases where a diagnosis could not be made other than by using en-doscopic retrograde cholangiopancreatography and in cases of pancreatic neoplasms or cystic tumors, includ-ing intraductal papillary mucinous neoplasm(IPMN) suspected to have malignant potential. 35 patients(21 males and 14 females) underwent ENPD between January 2007 and June 2013. The pancreatic duct was imaged and the procedure continued in one of ENPD-C or ENPD-C plus brush cytology(ENPD-BC). We checked the cytology result and the final ***: The mean patient age was 69 years(range, 48-86 years). ENPD-C was performed in 24 cases andENPD-C plus brush cytology(ENPD-BC) in 11 cases. The ENPD tube was inserted for an average of 3.5 d. The final diagnosis was confirmed on the basis of the resected specimen in 18 cases and of follow-up findings at least 6 mo after ENPD in the 18 inoperable cases. Malignancy was diagnosed in 21 cases and 14 patients were diagnosed as having a benign condition. The ratios of class Ⅴ/Ⅳ:Ⅲ:Ⅱ/Ⅰ?findings were 7:7:7 in malignant cases and 0:3:11 in benign cases. The sensitivity and specificity for all patients were 33.3% and 100%, re-spectively. The cytology-positive rate was 37.5%(6/16) for pancreatic cancer. For IPMN cases, the sensitivity and specificity were 33% and 100%, ***: Sensitivity may be further increased by adding brush cytology. Although we can diagnosis cancer in cases of a positive result, the accuracy of ENPD-C remains unsatisfactory.

关键词： Endoscopic naso-pancreatic drainage Pancreatic juice Cytology Pancreatic cancer Intraductal papillary mucinous neoplasm

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亚铬溶液在分析化学上的应用——液流连续分析体系监测环境水中的汞

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高等学校化学学报 1985年第10期6卷 887-890页

作者：田笠卿後藤正志石井大道南京大学化学系名古屋大学工学部应用化学科

本文研究了在液流连续体系中还原汞,避免了用SnCl_(2)易生成偏锡酸沉淀的缺点,因此可用来测定和连续监测环境水中的汞,在0.5—6ppb范围内有良好的线性关系,检出限为0.1ppb.

关键词：监测环境连续监测分析化学液流线性关系连续体系汞

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在膳食诱导的肥胖小鼠中,硝苯地平改善缺血引起的血管重建过程

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中华高血压杂志 2012年第6期20卷 598-598页

作者： Tetsutaro Kito Rei Shibata Megumi Kondo Takashi Yamamoto Hirohiko Suzuki Masakazu ishii Toyoaki Murohara 罗冬梅叶鹏

肥胖是心血管疾病的危险因素之一，与血管功能受损相关。硝苯地平作为钙拮抗剂的一种，有许多除了降低血压以外的功能，如改善内皮细胞功能，降低氧化应激。

关键词：肥胖小鼠血管重建硝苯地平膳食诱导缺血内皮细胞功能心血管疾病危险因素

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使用计算机再现校正掩膜的反射全息扫描器

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中国激光 1983年第Z1期 639-639页

作者： Y.ishii K.Murata 日本北海道大学工程学院应用物理系

全息光栅扫描器在光学扫描装置中的应用的重要性在不断增加。本文描述一种全息扫描法,其中反射体积全息图记录在铬盐明胶板上,并以多边形的形式安置在一个圆筒的周围。这种扫描器以反射方式工作,便于做成紧凑的折叠型以及在布喇格条件... 详细信息

全息光栅扫描器在光学扫描装置中的应用的重要性在不断增加。本文描述一种全息扫描法,其中反射体积全息图记录在铬盐明胶板上,并以多边形的形式安置在一个圆筒的周围。这种扫描器以反射方式工作,便于做成紧凑的折叠型以及在布喇格条件下只有一级衍射。F是点源P与全息图平面之间的距离,圆筒的半径为r。旋转这个全息图,就会使无畸变的再现斑点沿一曲线轨迹扫描。在许多应用中都希望有一个平的扫描面。利用计算机再现全息图产生的非球面波前完成了场曲率校正工作。全息图跟平场平面间

关键词：透射全息图掩膜计算机扫描器

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Endoscopic band ligation for bleeding lesions in the small bowel

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World Journal of Gastrointestinal Endoscopy 2014年第10期6卷 488-492页

作者： Takashi Ikeya Naoki ishii Yuto Shimamura Kaoru Nakano Mai Ego Kenji Nakamura Koichi Takagi Katsuyuki Fukuda Yoshiyuki Fujita Department of Gastroenterology St.Luke’s International Hospital

AIM: To investigate the safety and efficacy of endo-scopic band ligation(EBL) for bleeding lesions in the small ***: This is a retrospective study evaluating EBL in six consecutive patients(three males, three fe-males, 46-86 years of age) treated between May 2009 and February 2014: duodenal vascular ectasia; 1, je-junal bleeding diverticulum; 1, ileal Dieulafoy's lesion; 1 and ileal bleeding diverticula; 3. The success of the initial hemostasis was evaluated, and patients were observed for early rebleeding(within 30 d after EBL), and complications such as perforation and abscess for-mation. Follow-up endoscopies were performed in four ***: Initial hemostasis was successfully achieved with EBL in all six patients. Eversion was not sufficient in four diverticular lesions. Early rebleeding occurred three days after EBL in one ileal diverticulum, and arepeat endoscopy revealed dislodgement of the O-band and ulcer formation at the banded site. This rebleeding was managed conservatively. Late rebleeding occurred in this case(13 and 21 mo after initial EBL), and re-EBL was performed. Follow-up endoscopies revealed scar formation and the disappearance of vascular lesions at the banded site in the case with a duodenal bleeding lesion, and unresolved ileal diverticula in three cases. Surgery or transarterial embolization was not required without any complications during the median follow-up period of 45(range, 2-83) ***: EBL is a safe and effective endoscopic treatment for hemostasis of bleeding lesions in the small bowel.

关键词： Endoscopic band ligation Small bowel Di-verticular hemorrhage Jejunal bleeding Ileal bleeding Therapeutic endoscopy Hemostasis

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Combination of type Ⅳ collagen 7S, albumin concentrations, and platelet count predicts prognosis of non-alcoholic fatty liver disease

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World Journal of Hepatology 2021年第5期13卷 571-583页

作者： Miwa Kawanaka Ken Nishino Katsunori ishii Tomohiro Tanikawa Noriyo Urata Mitsuhiko Suehiro Takako Sasai Ken Haruma Hirofumi Kawamoto Department of General Internal Medicine Kawasaki Medical SchoolOkayama 700-8505Japan

BACKGROUND Non-alcoholic fatty liver disease(NAFLD)is the most common cause of chronic liver disease and affects approximately 25%of the general global adult *** prognosis of NAFLD patients with advanced liver fibrosis is known to be *** is difficult to assess disease progression in all patients with NAFLD;thus,it is necessary to identify patients who will show poor *** To investigate the efficacy of non-invasive biomarkers for predicting disease progression in patients with *** We investigated biomarkers associated with mortality in patients with NAFLD who visited the Kawasaki Medical School General Medical Center from 1996 to 2018 and underwent liver biopsy and had been followed-up for>1 *** overall mortality and liver-related events during follow-up were calculated using the Kaplan-Meier analysis and compared using log-rank *** calculated the odds ratio and performed receiver operating characteristic curve analysis with logistic regression analysis to determine the optimal cut-off value with the highest prognostic *** We enrolled 489 patients who were followed-up for a period of 1-22.2 *** total,13 patients died(2.7%of total patients enrolled);7 patients died due to liverrelated *** prognosis was associated with liver fibrosis on histological examination but not with inflammation or *** biomarkers associated with mortality were platelet counts,albumin levels,and type IV collagen 7S *** optimal cutoff index for predicting total mortality was a platelet count of 15×10^(4)/μL,albumin level of 3.5 g/dL,and type IV collagen 7S level of 5 mg/*** particular,only one-factor patients with NAFLD presenting with platelet counts≤15×10^(4)/μL,albumin levels≤3.5 g/dL,or type IV collagen 7S≥5 mg/dL showed 5-year,10-year,and 15-year survival rates of 99.7%,98.3%,and 94%,***,patients with two factors had lower 5-year and 10-year survival rates of 98%and 43%,respect

关键词： Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Platelet count Albumin Type IV collagen 7S All-cause mortality

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真空中交流电压下聚合物沿面闪络前的发光特性

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西安交通大学学报 2000年第4期34卷 10-13页

作者：张冠军杨敏中严璋刘源兴石井彰三西安交通大学西安710049 东京工业大学

以聚四氟乙烯为例研究了交流电压下聚合物绝缘材料在真空中沿面闪络发生前的表面发光特性 .观察到了两个明显不同的发光阶段 :较低电压下的低发光量的稳定发光 (A阶段 )和稍高电压下的剧烈、无规则的发光 (B阶段 ) .认为A阶段的发光是... 详细信息

以聚四氟乙烯为例研究了交流电压下聚合物绝缘材料在真空中沿面闪络发生前的表面发光特性 .观察到了两个明显不同的发光阶段 :较低电压下的低发光量的稳定发光 (A阶段 )和稍高电压下的剧烈、无规则的发光 (B阶段 ) .认为A阶段的发光是由于从电极注入的电子与空穴在绝缘体表层内的复合而引起的电致发光 ;对于B阶段 ,则提出了一种新的模型。

关键词：沿面闪络电致发光聚合物绝缘材料交注电压

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Comprehensive review of post-liver resection surgical complications and a new universal classification and grading system

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World Journal of Hepatology 2014年第10期6卷 745-751页

作者： Masayuki ishii Toru Mizuguchi Kohei Harada Shigenori Ota Makoto Meguro Tomomi Ueki Toshihiko Nishidate Kenji Okita Koichi Hirata Department of Surgery Surgical Oncology and ScienceSapporo Medical University Postgraduate School of Medicine

Liver resection is the gold standard treatment for certain liver tumors such as hepatocellular carcinoma and metastatic liver tumors. Some patients with such tumors already have reduced liver function due to chronic hepatitis, liver cirrhosis, or chemotherapy-associated steatohepatitis before surgery. Therefore, complications due to poor liver function are inevitable after liver resection. Although the mortality rate of liver resection has been reduced to a few percent in recent case series, its overall morbidity rate is reported to range from 4.1% to 47.7%. The large degree of variation in the post-liver resection morbidity rates reported in previous studies might be due to the lack of consen-sus regarding the definitions and classification of postliver resection complications. The Clavien-Dindo(CD) classification of post-operative complications is widely accepted internationally. However, it is hard to apply to some major post-liver resection complications because the consensus definitions and grading systems for posthepatectomy liver failure and bile leakage established by the International Study Group of Liver Surgery are incompatible with the CD classification. Therefore, a unified classification of post-liver resection complications has to be established to allow comparisons between academic reports.

关键词： Complication Liver failure Bile leakage Renal failure Ascites Coagulation disorder Surgical site infection

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Repeat endoscopic submucosal dissection for recurrent gastric cancers after endoscopic submucosal dissection

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World Journal of Gastrointestinal Endoscopy 2013年第12期5卷 600-604页

作者： Yuto Shimamura Naoki ishii Kaoru Nakano Takashi Ikeya Kenji Nakamura Koichi Takagi Katsuyuki Fukuda Koyu Suzuki Yoshiyuki Fujita Department of Gastroenterology St. Luke’s International Hospital Department of Pathology St. Luke’s International Hospital

AIM:To clarify the safety and efficacy of repeat endoscopic submucosal dissection(re-ESD)for locally recurrent gastric cancers after ***:A retrospective evaluation was performed of the therapeutic efficacy,complications and followup results from ESD treatment for early gastric cancers in 521 consecutive patients with 616 lesions at ***`s International Hospital between April 2004 and November *** addition,tumor size,the size of resected specimens and the operation time were compared between re-ESD and initial ESD procedures.A flex knife was used as the primary surgical device and a hook knife was used in cases with severe fibrosis in the submucosal *** variables were analyzed using the non-parametric Mann-Whitney U test and are expressed as medians(range).Categorical variables were analyzed using a Fisher’s exact test and are reported as *** significance was defined as a P-value less than ***:The number of cases in the re-ESD group and the initial ESD group were 5 and 611,*** median time interval from the initial ESD to re-ESD was 14(range,4-44 mo).En bloc resection with free lateral and vertical margins was successfully performed in all re-ESD cases without any *** local or distant recurrence was observed during the median follow-up period of 48(range,11-56 mo).Tumor size was not significantly different between the re-ESD group and the initial ESD group(median 22 mm vs 11mm,P=0.09),although the size of resected specimens was significantly larger in the re-ESD group(median 47 mm vs 34 mm,P<0.05).There was a nonsignificant increase observed in re-ESD operation time compared to initial ESD(median 202 min vs 67 min,respectively,P=0.06).CONCLUSION:Despite the low patient number and short follow-up,the results suggest that re-ESD is a safe and effective endoscopic treatment for recurrent gastric cancer after ESD.

关键词： Endoscopic submucosal dissection Recurrent gastric cancer Gastric cancer Endoscopic mucosal resection Therapeutic endoscopy

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基于元胞自动化模型的三维雪花晶体近似模式的产生(英文)

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山东大学学报（工学版） 2009年第1期39卷 102-105,117页

作者：李芳佳高尚策唐政石井雅博山下和也富山大学工学部

关于雪花生长过程的计算机模拟已经受到了广泛关注.其中,元胞自动化模型是一种基于网格和简单规则的计算方法.尽管这是一种简单的模型,但其在模拟复杂过程(比如:生命现象,晶体生长和湍流)时往往能取得较好的结果.提出了一种由传统的二... 详细信息

关于雪花生长过程的计算机模拟已经受到了广泛关注.其中,元胞自动化模型是一种基于网格和简单规则的计算方法.尽管这是一种简单的模型,但其在模拟复杂过程(比如:生命现象,晶体生长和湍流)时往往能取得较好的结果.提出了一种由传统的二维模型扩展而来的三维雪花晶体生长方法.计算机模拟结果显示提出的方法能够更精确地模拟出三维雪花的晶体化过程.

关键词：雪花晶体近似模式元胞自动化模型

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