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Friction 2017年第2期5卷 155-170页

作者： Munish k.GUPTA P.k.sood MED NIT Hamirpur(H.P.)177005 India

The prediction and optimization of surface roughness values remain a critical concern in nano-fluids based minimum quantity lubrication (NFMQL) turning of titanium (grade-2) ***,we discuss an application of response surface methodology with Box-Cox transformation to determine the optimal cutting parameters for three surface roughness values,i.e.,Ra,Rq,and Rz,in turning of titanium alloy under the NFMQL *** surface roughness prediction model has been established based on the selected input parameters such as cutting speed,feed rate,approach angle,and different nano-fluids *** the multiple regression technique is used to find the relationship between the given responses and input ***,the experimental data were optimized through the desirability function *** findings from the current investigation showed that feed rate is the most effective parameter followed by cutting speed,different nano-fluids,and approach angle on Ra and Rq values,whereas cutting speed is more effective in the case of Rz under NFMQL ***,the predicted results are comparatively near to the experimental values and hence,the established models of RSM using Box-Cox transformation can be used for prediction satisfactorily.

关键词： nano-fluids optimization surface roughness turning titanium alloy

Hepatocellular carcinoma review:Current treatment,and evidence-based medicine

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World Journal of Gastroenterology 2014年第15期20卷 4115-4127页

作者： Ali Raza Gagan k sood Department of Internal Medicine St. Luke’s Episcopal HospitalBaylor College of MedicineHoustonTX 77030United States Division of Gastroenterology and Hepatology Baylor College of MedicineSt. Luke’s Liver CenterHoustonTX 77030United States

Hepatocellular carcinoma(HCC)is the fifth most common tumor *** treatment options are available for HCC including curative resection,liver transplantation,radiofrequency ablation,trans-arterial chemoembolization,radioembolization and systemic targeted agent like *** treatment of HCC depends on the tumor stage,patient performance status and liver function reserve and requires a multidisciplinary *** the past few years with significant advances in surgical treatments and locoregional therapies,the short-term survival of HCC has improved but the recurrent disease remains a big *** pathogenesis of HCC is a multistep and complex process,wherein angiogenesis plays an important *** patients with advanced disease,sorafenib is the only approved therapy,but novel systemic molecular targeted agents and their combinations are *** article provides an overview of treatment of early and advanced stage HCC based on our extensive review of relevant literature.

关键词： Hepatocellular carcinoma Trans-arterial chemoembolization Drug-eluting beads Radiofrequency ablation Liver transplantation Chemotherapy Sorafenib Radioembolization

Hepatitis C Associated B-cell Non-Hodgkin Lymphoma:Clinical Features and the Role of Antiviral Therapy

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Journal of Clinical and Translational Hepatology 2015年第2期3卷 134-139页

作者： Syed Tasleem Gagan k sood Department of Surgery St.Luke's Center for Liver Disease Baylor College of Medicine Houston Texas USA Department of Surgery St.Luke's Center for Liver Disease Baylor College of Medicine Houston Texas USA Department of Gastroenterology and Hepatology Baylor College of Medicine Houston Texas USA

The link between chronic hepatitis C virus (HCV) infection and a subset of B-cell non-Hodgkin lymphomas (B-NHL) is strongly supported by epidemiological *** demonstrating complete regression of lymphoma after antiviral treatments suggests possible chronic antigenic stimulation for the origin of B-NHL and provides evidence for a virus-mediated lymphomagenesis.B-NHL is a heterogeneous group of lymphomas with varied clinical presentation and may be indolent or *** optimal management of HCV related B-NHL is not *** treatment may be sufficient for low-grade lymphomas,but chemotherapy is necessary in patients with high grade *** (IFN)-based antiviral treatment regimens for HCV infection are limited by poor tolerance and suboptimal antiviral *** approved novel direct acting antiviral (DAA) drugs are highly effective and *** has opened a new era for the treatment of HCV related B-NHL alone or in conjunction with *** of HCV associated B-NHL should be performed in an interdisciplinary approach in close consultation with hematologist and *** this review,we summarize data regarding clinical features and epidemiology of B-NHL and discuss novel therapeutic approaches,including DAAs,that may prove to be effective in the treatment of HCV associated lymphomas.

关键词： Hepatitis C Non-Hodgkin lymphoma Mixed cryoglobulinemia Rituximab

Advancing frontiers in anaesthesiology with laparoscopy

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World Journal of Gastroenterology 2014年第39期20卷 14308-14314页

作者： Jayashree sood Department of Anaesthesiology Pain and Perioperative Medicine Sir Ganga Ram Hospital Old Rajinder Nagar New Delhi 110060 India

The introduction of laparoscopy in the surgeon’s armamentarium was in fact a “revolution in the history of surgery”. Since this technique involves insufflation of carbon dioxide it produces several pathophysiological changes which have to be understood by the anaesthesiologist who can modify the anaesthesia technique accordingly. Advantages of laparoscopy include reduced pain, small scars and early return to work. Certain complications specific to laparoscopic surgery are due to carboperitoneum and increased intra-abdominal pressure. Venous air embolism, although very rare, can be lethal if not managed promptly. Other complications include subcutaneous emphysema, haemodynamic compromise and arrhythmias. Although associated with minimal postoperative morbidity, postoperative pain, nausea and vomiting can be quite problematic. The limitations of laparoscopy have been overcome by the introduction of robotic surgery. There are important implications for the anaesthesiologist during robotic surgeries which have to be practiced accordingly. Robotic surgery has a learning curve for both the surgeon and the anaesthesiologist. The robot is bulky, and cannot be disengaged after docking. Therefore it is important that the anaesthetized patient remains immobile throughout surgery and anaesthesia is reversed only after the robot has been disengaged at the end of surgery. Advances in laparoscopy and robotic surgery have modified anaesthetic techniques too.

关键词： Laparoscopy Anaesthesia Robotic Advances Pathophysiological changes Complications

Fragment emission and critical behavior in light and heavy charged systems

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Chinese Physics C 2021年第1期45卷 215-225页

作者： Samiksha sood Rohit kumar Arun Sharma Sakshi Gautam Rajeev k.Puri Department of Physics Panjab UniversityChandigarh 160014India Department of Physics G.D.College.BillawarJammu 185204India

We study the emission of fragments in central collisions of light and heavily charged systems of^4+Ar+^45 Sc and^s4kr+^197 Au,respectively,using the Quantum Molecular Dynamics(QMD)model as the primary *** fragments are identified using an energy based clusterization algorithm,i.e.,the Simulated Annealing Clusterization Algorithm(SACA).The charge distributions of intermediate mass fragments[3≤Zf≤12]are fitted with power-law(∝Zf^-τ)and exp on ential(∝e^-λZf)fits in order to extract the parametersτandλ,whose minimum values are also sometimes linked with the onset of fragmentation or the critical point for a liquid-gas phase *** parameters such as the normalized second moment,,average size of the second largest cluster,phase separation parameter(Sp),bimodal parameter(P),information entropy(H),and Zipfs law are also analyzed to find the exact energy of the onset of *** detailed analysis predicts that an energy point exists between 20-23.1 MeV/nucleon,which is very close to the experimentally observed value of 23.9 MeV/nucleon for the^40Ar+^45Sc *** also find that the critical energy deduced using Zipfs law is higher than those predicted from other critical ***,no minimum is found for t values of the highly charged system of^84kr+^197Au,in agreement with experimental findings and various theoretical *** observe that the QMD+SACA model calculations are in agreement with the experimental *** agreement supports our results regarding the energy point of the liquid-gas phase transition and the onset of fragmentation.

关键词： heavy-ion collisions transport model clusterization algorithm Monte-Carlo technique li・quid-gas phase transition

Tribological response of waste tire rubber as micro-fillers in automotive brake lining materials

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Friction 2020年第6期8卷 1153-1168页

作者： Anand PAI Sayikumar SUBRAMANIAN Tribhuvan sood Department of Aeronautical and Automobile Engineering Manipal Institute of TechnologyManipal Academy of Higher Education ManipalKarnataka 576104lIndia Cranfield University CranfieldMilton KeynesBedfordshire MK430ALUK

Elastomeric materials show promise as potential micro-fillers in brake *** can provide vibration damping and acoustic advantages in intermittent and abrupt impact applications such as *** elastomeric material can be salvaged from non-biodegradable automotive tires,thereby providing an opportunity to reuse materials that will otherwise be discarded in *** tribological and thermomechanical performances of the waste tire rubber were assessed to determine their potential for use as micro-fillers in the brake linings of commercial vehicles with a gross weight less than 16 ***,the brake lining materials were fabricated with fine waste tire rubber particulates(WTRPs)as the micro-fillers,phenolic-R resin as the binder,graphite as the dry lubricant,laterite as the co-filler,and coconut coir for natural fiber *** effects of increasing the WTRP weight fraction on the brake response of the linings were analyzed,and the different compositions were benchmarked against a commercial brake *** characterization comprising compressive strength,hardness,density,and porosity studies were carried *** and wear characteristics of the linings were analyzed using a rotary tribometer with simultaneous thermal *** manufactured lining with 15 wt%WTRPs exhibited a mean friction coefficient of^0.38,a specific volumetric loss rate of 1,662μm3/(N?m),and improved thermal *** optical microscopy and scanning electron microscopy(SEM)with energy dispersive spectroscopy(EDS),wear surface morphology studies compared the relative development of primary and secondary plateaus and revealed the redistribution of wear debris,leading to the stability of the coefficient of friction.

关键词： automotive brakes elastomers graphite energy dispersive spectroscopy(EDS) scanning electron microscopy(SEM) wear mechanisms

TLERAD: Transfer Learning for Enhanced Ransomware Attack Detection

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Computers, Materials & Continua 2024年第11期81卷 2791-2818页

作者： Isha sood Varsha Sharm a School of Information Technology Rajiv Gandhi Proudyogiki VishwavidyalayaBhopal462033India

Ransomware has emerged as a critical cybersecurity threat,characterized by its ability to encrypt user data or lock devices,demanding ransom for their *** ransomware detection methods face limitations due to their assumption of similar data distributions between training and testing phases,rendering them less effective against evolving ransomware *** paper introduces TLERAD(Transfer Learning for Enhanced Ransomware Attack Detection),a novel approach that leverages unsupervised transfer learning and co-clustering techniques to bridge the gap between source and target domains,enabling robust detection of both known and unknown ransomware *** proposed method achieves high detection accuracy,with an AUC of 0.98 for known ransomware and 0.93 for unknown ransomware,significantly outperforming baseline *** experiments demonstrate TLERAD’s effectiveness in real-world scenarios,highlighting its adapt-ability to the rapidly evolving ransomware *** paper also discusses future directions for enhancing TLERAD,including real-time adaptation,integration with lightweight and post-quantum cryptography,and the incorporation of explainable AI techniques.

关键词： Ransomware detection transfer learning unsupervised learning co-clustering cybersecurity machine learning lightweight cryptography post-quantum cryptography explainable AI TLERAD