Hepatocellular carcinoma review:Current treatment,and evidence-based medicine

作     者：Ali Raza Gagan K Sood 

作者机构：Department of Internal MedicineSt. Luke’s Episcopal HospitalBaylor College of MedicineHoustonTX 77030United States Division of Gastroenterology and HepatologyBaylor College of MedicineSt. Luke’s Liver CenterHoustonTX 77030United States 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第15期

页      面：4115-4127页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Hepatocellular carcinoma Trans-arterial chemoembolization Drug-eluting beads Radiofrequency ablation Liver transplantation Chemotherapy Sorafenib Radioembolization 

摘      要：Hepatocellular carcinoma(HCC)is the fifth most common tumor *** treatment options are available for HCC including curative resection,liver transplantation,radiofrequency ablation,trans-arterial chemoembolization,radioembolization and systemic targeted agent like *** treatment of HCC depends on the tumor stage,patient performance status and liver function reserve and requires a multidisciplinary *** the past few years with significant advances in surgical treatments and locoregional therapies,the short-term survival of HCC has improved but the recurrent disease remains a big *** pathogenesis of HCC is a multistep and complex process,wherein angiogenesis plays an important *** patients with advanced disease,sorafenib is the only approved therapy,but novel systemic molecular targeted agents and their combinations are *** article provides an overview of treatment of early and advanced stage HCC based on our extensive review of relevant literature.