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Unraveling the morphological patterns of a subantarctic eelpout:a geometric morphometric approach

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Integrative Zoology 2023年第2期18卷 372-384页

作者： Fernanda S.ORREGO Mathias HÜNE Hugo a.benÍTEZ Mauricio F.LANDAETA Laboratorio de Ictiología e Interacciones Biofísicas(LABITI) Instituto de BiologíaFacultad de CienciasUniversidad de ValparaísoValparaísoChile Centro de Investigación para la Conservación de los Ecosistemas Australes(ICEA) Punta ArenasChile Laboratorio de Ecología y Morfometría Evolutiva Centro de Investigación de Estudios Avanzados del MauleUniversidad Católica del MauleTalcaChile Centro de Observación Marino para Estudios de Riesgos del Ambiente Costero(COSTA-R) Universidad de ValparaísoViña del MarChile Millennium Nucleus for Ecology and Conservation of Temperate Mesophotic Reef Ecosystems(NUTME) Millennium Institute Biodiversity of Antarctic and Subantarctic Ecosystems(BASE) SantiagoChile

Phenotypic variation in organisms depends on the genotype and the environmental constraints of the habitat that they ***,for marine species inhabiting contrasting aquatic conditions,it is expected toﬁnd covari-ation between the shape and its spatial *** studied the morphology of the head and cephalic sensory canals of the eelpout Austrolycus depressiceps(4.5–22.5 cm TL)across its latitudinal distribution in South Paciﬁc(45°S–55°S).Geometric morphometric analyses show that the shape varied from individuals with larger snout and an extended suborbital canal to individuals with shorter snouts and frontally compressed suborbital *** was size variation across the sampled populations,but that size does not have a clear latitudinal *** 8%of the shape variation relates to this size variation(allometry),represented by a decrease in the relative size of the eye,and a depression of the posterior margin of the *** were spatial differences in the shape of the head,but these differences were probably caused by allometric ***,2 of the canals of the cephalic lateralis pores and the head shape showed modularity in its *** study shows that the morphology of marineﬁsh with a shallow distribution varies across distances of hundreds of kilometers(i.e.,phenotypic modulation).

关键词： Austrolycus depressiceps geometric morphometrics morphology phenotype spatial distribution

Reducing dietary sodium of dairy cows fed a low-roughages diet affect intake and feed efficiency,but not yield

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Animal Nutrition 2023年第1期12卷 1-6页

作者： Yehoshav a.ben Meir Yoav Shaani Daniel Bikel Yuri Portnik Shamai Jacoby Uzi Moallem Joshua Miron Eyal Frank Department of Ruminant Science Institute of Animal ScienceAgricultural Research Organization(ARO)Rishon Lezion 7528809Israel Department of Animal Production Extension ServiceMinistry of AgricultureRishon Lezion 7528809Israel

Wastewater from dairy farms has become a major environmental and economical *** residue in treated and untreated wastewater from dairy farms used for irrigation can lead to soil and groundwater salinization,with the risk of soil *** examined the effect of reducing sodium fed to mid to late lactating cows from 0.61%(high sodium[HS])to 0.45%(low sodium[LS])of dry matter on dry matter intake(DMI),milk and milk-component yields,eating behavior,apparent total track digestibility,feed efficiency,and sodium excretion into the *** randomly assigned 28 multiparous high-yielding(>35 kg milk/d)cows to 1 of 2 treatment groups(LS or HS)in a crossover design,with 7 d of adaptation and 28 d of data *** sodium in the diet reduced sodium intake from 171 to 123 g/d while lowering sodium excreted in the manure by 22%.Energy corrected milk(ECM)yield(37.4 kg/d)and sodium excretion in the milk(33.7 g/d)were similar for both *** DMI of LS cows was lower than that of HS cows(27.3 vs.28 kg/d)and consequently,feed efficiency of the LS cows was higher(1.40 vs.1.35 ECM/DMI).Eating rate,meal and visit frequency,and eating time were similar for both treatments;meal and visit duration were longer for the HS cows,and meal and visit sizes tended to be *** of DM and amylase-treated neutral detergent fiber remained *** on the results of this study,and discussed considerations,we recommend lowering the dietary sodium content for mid to late lactating cows in commercial herds to 0.52%of DM,in order to reduce sodium excretion to the environment via urine.

关键词： Mineral absorption Sodium Eating behavior Environmentally friendly dairy farm

An Improved Experiment to Determine the‘Past of a Particle’in the Nested Mach-Zehnder Interferometer

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Chinese Physics Letters 2017年第2期34卷 4-6页

作者： a.ben-Israel L.Knips J.Dziewior J.Meinecke A.Danan H.Weinfurter L.Vaidman Raymond and Beverly Sackler School of Physics and Astronomy Tel-A viv UniversityTel-A viv 69978Israel Max-Planck-Institut für Quantenoptik Hans-Kopfermann-Straβe 1Garching 85748Germany Department für Physik Ludwig-Maxirnilians-UniversitatMunchen 80797Germany

We argue that the modification proposed by Li et al. [Chin. Phys. Lett. 32 （2015）050303] to the experiment of Danan et al. [Phys. Rev. Lett. 111 （2013） 240402] does not test the past of the photon as characterized by local weak traces. Instead of answering the questions：（i） were the photons in A？（ii） were the photons in B？ and （iii） were the photons in C？ the proposed experiment measures a degenerate operator answering the questions：（i） were the photons in A？ and （ii） were the photons in B and C together？ A negative answer to the last question does not tell us if photons were present in B or C. On the other hand, a simple variation of the proposal by Li et al. does provide conceptually better evidence for the past of the pre- and post-selected photon, but this evidence will be in agreement with the results of Danan et al.

关键词： Li In in the Nested Mach-Zehnder Interferometer An Improved Experiment to Determine the

Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia

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World Journal of Gastroenterology 2010年第4期16卷 479-483页

作者： Imen Sfar Walid ben Aleya Leila Mouelhi Houda Aouadi Thouraya.ben Rhomdhane Mouna makhlouf Salwa Ayed-Jendoubi Houda Gargaoui Taoufik Najjar Taieb ben Abdallah Khaled Ayed Yousr Gorgi Laboratory of Immunology Charles Nicolle HospitalTunis 1006Tunisia Department of Gastroenterology Charles Nicolle HospitalTunis 1006Tunisia

AIM:To assess the possible association between PTPN22(R620W) gene polymorphism and inflammatory bowel disease(IBD).METHODS:One hundred and sixty-four patients with IBD 105 Crohn's disease(CD) and 59 ulcerative colitis(UC) and 100 healthy controls were *** of the PTPN22 gene 1858C→T polymorphism was performed by restriction fragment length polymorphism-polymerase chain reaction with Rsa Ⅰ ***:The genotypic and allelic frequencies of(R620W) PTPN22 gene polymorphism reveal a significant association of the PTPN22 620-W allele with IBD,compared to the healthy control group(OR:17.81,95% CI:4.18-21.86,P = 0.00001).Nevertheless,nodifference in this polymorphism was found between CD and UC *** significant association was found between the frequencies of genotypes of the PTPN22 gene with either the clinical features such as sex,age,age at disease onset,and extent of colitis,or the production of serological markers(anti-Saccharomyces cerevisiae antibody in CD and perinuclear anti-neutrophil cytoplasmic antibody in UC).CONCLUSION:These observations confirm the association of IBD susceptibility with the PTPN22 1858T(620-W) allele in Tunisian patients.

关键词： Inflammatory bowel disease PTPN22 Genetic polymorphism Genetic susceptibility

Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD

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World Journal of Gastroenterology 2009年第29期15卷 3643-3648页

作者： Walid ben Aleya Imen Sfar Leila Mouelhi Houda Aouadi Mouna makhlouf Salwa Ayed-Jendoubi Samira Matri Azza Filali Taoufik Najjar Taeib ben Abdallah Khaled Ayed Yousr Gorgi Laboratory of Immunology EPS Charles Nicolle 1006 Bab Saadoun Tunis 1006 Tunisia Department of Gastroenterology EPS Charles Nicolle Tunis 1006 Tunisia Department of Gastroenterology La Rabta Tunis 1006 Tunisia

AIM： To detect a possible association between the polymorphism of the （-670 A/G） Fas/Apol gene promoter and susceptibility to Crohn＇s disease （CD） and ulcerative colitis （UC） in the Tunisian population. METHODS： The （-670 A/G） Fas polymorphism was analyzed in 105 patients with CD, 59 patients with UC, and 100 controls using the polymerase chain reaction restriction fragment length polymorphism method. RESULTS： Significantly lower frequencies of the Fas -670 A allele and A/A homozygous individuals were observed in CD and UC patients when compared with controls. Analysis of （-670 A/G） Fas polymorphism with respect to sex in CD and UC showed a significant difference in A/A genotypes between female patients and controls （P corrected = 0.004 ＂in CD patients＂ and P corrected = 0.02 ＂in UC patients＂, respectively）. Analysis also showed a statistically significant association between genotype AA of the （-670 A/G） polymorphism and the ileum localization of the lesions （P corrected = 0.048） and between genotype GG and the colon localization （P corrected = 0.009）. The analysis of IBD patients according to clinical behavior revealed no difference. CONCLUSION： Fas-670 polymorphism was associated with the development of CD and UC in the Tunisian population.

关键词： Fas/Apol Gene polymorphisms Inflammatory bowel disease Crohn's disease Ulcerative colitis

Natural evolution of hepatitis C virus infection in hemodialysis Tunisian patients and CTLA-4 SNP's

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World Journal of Gastroenterology 2015年第35期21卷 10150-10158页

作者： Leila Ksiaa Cheikhrouhou Yousr Lakhoua-Gorgi Imen Sfar Salwa Jendoubi-Ayed Houda Aouadi Mouna makhlouf Khaled Ayed Taieb ben Abdallah Immunology Research Laboratory of Kidney Transplantation and Immunopathology Laboratoire de Recherche Laboratory of Immunology Charles Nicolle Hospital

AIM: To analyze the polymorphisms of CTLA-4 gene involved in the response against hepatitis C virus(HCV) ***: We recruited 500 hemodialysed patients from several hemodialysis centers, all HCV-antibody positive, spread over different regions of Tunisia, as part of a national survey in 2008 conducted in the laboratory of immunology at the Charles Nicolle hospital Tunisia, classified into two groups G1(PCR+) and G2(PCR-) according to the presence or absence of viral RNA. Of these patients, 307 were followed prospectively on a viral molecular level over a period from 2002 to 2008, divided into two groups based on the persistence and viral clearance. PCR-RFLP was performed for the analysis of SNPs(+49) A/G and(+6230) G/A CTLA-4 for these 500 patients and 358 healthy ***: Analysis of clinical and virological charac-teristics of our cohort suggests a nosocomial infection in our hemodialysed patients with transfusion history as a primary risk factor and a predominance of genotype 1b. The haplotype analysis revealed an increase of frequencies of GG(+49)/(CT60) CTLA-4 in the entire patients group compared to controls(P = 0.0036 and OR = 1.42; 95%CI: 1.12-1.79, respectively). This haplotype is therefore associated with susceptibility to HCV infection. CONCLUSION: Our study suggests a possible role of CTLA-4 polymorphisms in the outcome of HCV infection in the Tunisian hemodialysed population.

关键词： Hepatitis C virus Hemodialysis Natural evolution C

骨吸收因子DKK1在慢性牙周炎龈沟液的表达

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骨吸收因子DKK1在慢性牙周炎龈沟液的表达

作者： Mohamed Ramadan a.ben lamin（罗马）中南大学

学位级别：硕士

背景：牙周炎是发病率较高的口腔炎症性疾病之一,牙槽骨的吸收是慢性牙周炎主要的及最严重的病变,是造成牙齿缺失的主要原因.DKK1是wnt信号通路主要抑制剂之一,是一种重要的检测骨丧失的标记物。因而慢性牙周炎患者龈沟液中DKK1的水平... 详细信息

背景：牙周炎是发病率较高的口腔炎症性疾病之一,牙槽骨的吸收是慢性牙周炎主要的及最严重的病变,是造成牙齿缺失的主要原因.DKK1是wnt信号通路主要抑制剂之一,是一种重要的检测骨丧失的标记物。因而慢性牙周炎患者龈沟液中DKK1的水平的检测可能作为评价牙槽骨丧失的新的生物标志物。方法：本研究共28位研究对象分为三组：中重度牙周炎13例,轻度牙周炎10例,5例健康对照组,所有观察对象取右下第一磨牙为受试牙,检查和记录牙周临床指标：牙龈指数(GI),牙周探诊深度(PD)及临床附着丧失(CAL)。在牙周基础治疗前后采集龈沟液,采集方法为滤纸条沟内取样法。DKK1水平的检测分别在洁治后1周,刮治后1周以及刮治后1月。使用酶联免疫吸附分析法检测龈沟液中DKK1的浓度,并进行统计学处理,分析DKK1与GI、PD及CAL的关系。结果：1.龈沟液中DKK1的浓度和GI、PD、CAL呈正相关,相关系数分别为0.447,0.611,0.678。2.洁治后1周DKK1在中重度组中浓度为8.6692±1.97497ug/L,轻度组7.1560±54557ug/L,正常组为6.83±1.06ug/L.,各组间相比P<0.05差异有统计学意义。刮治后1周中重度组DKK1浓度为9,47±1.99ug/L,刮治后1月为8.21±1.68ug/L,两者比较差异有统计学意义。结论：1.研究显示龈沟液中DKK1浓度和慢性牙周炎的严重程度呈正相关。***1可能成为一种重要的新指标而应用于牙周炎的临床检测。

关键词：慢性牙周炎 DKK1 骨吸收龈沟液酶联免疫吸附分析

Revisiting the Dirichlet-to-Neumann Solver for Data Completion and Application to Some Inverse Problems

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Revisiting the Dirichlet-to-Neumann Solver for Data Completi...

Zwitterionic hyaluronic acid derivatives for co-delivery of both chemotherapeutic and nucleic acid drugs in breast cancer treatment

The Sixth World Congress on Computational Mechanics in Conjunction with the Second Asian-Pacific Congress on Computational Mechanics

作者： M.Azaiez a.ben Abda J.ben Abdallah F.ben Belgacem MASTER Ecole Nationale Sup erieure de Chimie et de Physique de Bordeaux.16 avenue Pey Berland 33607 Pessac Cedex France LAMSIN Ecole Nationale d'Ing'enieurs de Tunis Campus Universitaire BP 37 1002 Tunis Belv'ed'ere Tunisia LAMSIN Ecole Nationale d'Ing'enieurs de Tunis Campus Universitaire BP 37 1002 Tunis Belv'ed'ere Tunisia Institut Sup 'erieur des Sciences Appliqu 'ees et de Technologie de Sousse Cit 'e affala-Ibn Khaldoun 4003 Sousse Tunisia MIP (UMR CNRS 5640) Universit'e Paul Sabatier 118 route de Narbonne 31062 Toulouse Cedex 04 France

We are concerned in this work with a data completion numerical pr ocedure proposed by Koslov et al. in [1]. Computationnal examples are presented and discussed to test the capability of this algorithm and to show how ...

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Nano Research 2025年第1期18卷 607-617页

作者： Ruo-Lin Jiang Hui-Na Liu Yu-Fan Yang Zhi-Cheng Zhang Qi Dai Xiao-Yan Bao Lin-Jie Wu Ya-Xin Qin Xin Tan Xiao-Yan Sun Xu-Fang Ying Zhi-Qing ben Min Han Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of Radiation Oncology Key Laboratory of Cancer Prevention and InterventionThe Second Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310058China Hangzhou Institute of Innovative Medicine Zhejiang UniversityHangzhou 310058China Jinhua Institute of Zhejiang University Jinhua 321299China National Key Laboratory of Advanced Drug Delivery and Release Systems Zhejiang UniversityHangzhou 310058China Polytechnic institute Zhejiang UniversityHangzhou 310015China

Traditionally,hyaluronic acid has been widely used for drug delivery,but the current application bottleneck is that hyaluronic acid is hydrophilic and electronegative,which makes it difficult to carry hydrophobic drugs and small interfering RNA(siRNA)with the same *** on previous studies,we designed and synthesized hyaluronic acid nanocarriers HA-spermine/N,N,N-trimethylcystamine/DOX-TPP(HSTD)for loading siRNA to overcome the problem of siRNA release caused by strong electrostatic ***,N,N,Ntrimethylcystamine in the carrier can be degraded by intracellular glutathione to completely and rapidly release siRNA,thus promoting ***,when codelivered with the chemotherapy drug doxorubicin(DOX),this novel nanocarrier showed promising synergy in inhibiting tumor growth.

关键词： zwitterionic hyaluronic acid N N N-trimethylcystamine small interfering RNA(siRNA) doxorubicin