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VOCs废气危害及处理技术进展

化工管理 2018年第10期 125-127页

作者：胡桐搏张长平刘浩李若侬曹自青 Yabo abel Chat 河北工业大学能源与环境工程学院天津300401

VOCs废气是一类对环境和人类产生严重危害的废气,本文综述了VOCs的危害及国内外VOCs治理的传统技术和近年来发展的光催化氧化法、脉冲电晕法、生物法等处理技术的原理及优缺点,并展望处理工艺的前景。

关键词：挥发性有机物危害处理技术生物法

British Journal of General Practice论文摘要汇编——英格兰全科门诊紧急转诊或急诊室处理后的癌症诊断：2006—2015年“诊断途径”的决定因素和时间趋势

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中国全科医学 2019年第33期22卷 4040-4040页

作者： HERBERT a.abel G A WINTERS S 本刊编辑部

背景癌症作为一种急症,其诊断与患者不良结局相关,且原因复杂。探索癌症诊断途径中的决定因素和时间趋势,有助于了解全科诊疗在癌症患者诊断途径中的关键作用。目的探索发生紧急情况的癌症患者的表现类型与社会人口统计学、癌症部位以... 详细信息

背景癌症作为一种急症,其诊断与患者不良结局相关,且原因复杂。探索癌症诊断途径中的决定因素和时间趋势,有助于了解全科诊疗在癌症患者诊断途径中的关键作用。目的探索发生紧急情况的癌症患者的表现类型与社会人口统计学、癌症部位以及时间因素的关联。设计与场所针对2006—2015年英国癌症患者的“诊断途径”数据进行分析。方法根据患者性别、年龄、死亡组和诊断年份,使用多变量回归估计全科门诊紧急转诊(GP-EP)或急诊室处理(AE-EP)后癌症患者紧急表现的调整后比例。结果在发生紧急情况的554621名患者中,24%(n=130372)患者为GP-EP,62%(n=346192)患者为AE-EP,14%(n=78057)患者为其他转诊途径。患有胰腺癌、胆囊癌、卵巢癌或急性白血病的贫困地区患者,更可能被转诊到全科门诊。在研究期间,GP-EP的比例和数量几乎减半(2006年,n=17364,31%;2015年,n=9155,17%),而AE-EP的比例和数量增加(55%,n=31049,2006年;68%,n=36868,2015年)。结论患有癌症突发事件的患者,其特征为可耐受的症状/体征,医生应该对这类患者提高警惕(例如,表现为无痛性黄疸的胰腺癌)。通过紧急情况的癌症诊断的减少可能反映了研究期间“2周等待期”GP-EP的持续增加以及GP-EP的减少。

关键词：癌症诊断胆囊癌急性白血病等待期全科门诊不良结局多变量回归胰腺癌

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生活在同一屋顶下:北京可持续发展新模式

建筑创作 2015年第1期 50-79页

作者：克里斯·亚伯朱琳国际建筑师学会建筑评论家委员会不详

用一个醒目的外罩将一组低能耗的多功能建筑遮蔽起来,从而形成可调控的微气候环境,使建筑群免受风雨侵扰。不管起源于何种情境,＂北京芳草地＂激进的环境策略和建筑成就都会吸引全球的注意力。更引人注目的是,这是一处纯私人物业,由中... 详细信息

用一个醒目的外罩将一组低能耗的多功能建筑遮蔽起来,从而形成可调控的微气候环境,使建筑群免受风雨侵扰。不管起源于何种情境,＂北京芳草地＂激进的环境策略和建筑成就都会吸引全球的注意力。更引人注目的是,这是一处纯私人物业,由中国开发商投资、持有并运营,并由来自香港的华人建筑师进行设计。它的构思与建造,恰好与2008年奥运会场地同期。＂芳草地＂的故事,既有关于奥运给这座首都带来的冲击,

关键词：芳草地建筑协会微气候环境奥运会场屋顶下发展新模式多功能建筑低能耗 Olympics elsewhere

全科医生紧急转诊或急诊室接诊后癌症诊断路径的相关因素和时间趋势：基于英国2006—2015年癌症诊断路径数据的分析

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中国全科医学 2019年第36期22卷 4503-4503页

作者：本刊编辑部 HERBERT a.abel G A WINTERS S

背景紧急癌症诊断与患者病因复杂并具有不良预后相关。研究诊断路径相关因素与时间趋势有助于认识到长久以来全科医疗在癌症患者诊断路径中发挥的关键作用。目的调查被紧急诊断为癌症的患者的社会人口学因素、癌症部位和表现类型的时间... 详细信息

背景紧急癌症诊断与患者病因复杂并具有不良预后相关。研究诊断路径相关因素与时间趋势有助于认识到长久以来全科医疗在癌症患者诊断路径中发挥的关键作用。目的调查被紧急诊断为癌症的患者的社会人口学因素、癌症部位和表现类型的时间相关性。设计与场所对英国癌症患者2006—2015年的《诊断路径》资料进行研究。方法对调整后的经全科医生紧急转诊或急诊室接诊后诊断为癌症的患者比例进行分析,并采用多元回归按照患者性别、年龄、社会经济剥夺情况以及癌症诊断年对此进行亚组分析。结果共纳入554621例癌症患者,其中24%(n=130372)在经全科医生紧急转诊后诊断,62%(n=346192)在急诊室接诊后诊断,14%(n=78057)经其他亚途径诊断。经全科医生紧急转诊后的癌症患者中,来自社会经济状况良好的地区或后来诊断为胰腺癌、胆囊癌、卵巢癌或急性白血病的患者的比例较高。在研究期间,经全科医生紧急转诊后诊断为癌症的患者比例和数量几乎均下降了50%〔在2006年为31%(n=17364),而在2015年为17%(n=9155)〕,而在急诊室接诊后诊断为癌症的患者的比例和数量均有所增加〔在2006年为55%(n=31049),而在2015年为68%(n=36868)〕。结论经全科医生紧急转诊后诊断为癌症的患者临床表现多为患者可耐受但是全科医生却高度警惕的症状/体征(比如胰腺癌可表现为无痛性黄疸)。在研究期间,持续采用需等待2周才能经全科医生转诊的制度并增加此制度的应用范围和降低全科医生紧急转诊率可降低急诊转诊后癌症诊断率。

关键词：癌症诊断全科医生全科医疗社会人口学因素胆囊癌亚组分析急性白血病时间相关性

Reduction of the closure time of postoperative enterocutaneous fistulas with fibrin sealant

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World Journal of Gastroenterology 2010年第22期16卷 2793-2800页

作者： Jorge Avalos-González Eliseo Portilla-deBuen Caridad Aurea Leal-Cortés abel Orozco-Mosqueda María del Carmen Estrada-Aguilar Gabriela Abigail Velázquez-Ramírez Gabriela Ambriz-González Clotilde Fuentes-Orozco Aldo Emmerson Guzmán-Gurrola Alejandro González-Ojeda Research Unit in Clinical Epidemiology High Specialized Medical Unit Surgical Research Division National Western Medical Center Department of Surgery Regional General Hospital #1 of the Mexican Institute for Social Security Avenida Héroes de Nocupetaro y Nicolás de Regules Colonia Centro Department of Pediatric Surgery Children's Hospital National Western Medical Center

AIM: To assess whether the use of fibrin sealantshortens the closure time of postoperative enterocutaneous fistulas (ECFs). METHODS: The prospective case-control study included 70 patients with postoperative ECFs with an output of 2 cm and without any local complication. They were divided into study (n = 23) and control groups (n = 47). Esophageal, gastric and colocutaneous fistulas were monitored under endoscopic visualization, which also allowed fibrin glue application directly through the external hole. Outcome variables included closure time, time to resume oral feeding and morbidity related to nutritional support. RESULTS: There were no differences in mean age, fistula output, and follow-up. Closure-time for all patients of the study group was 12.5 ± 14.2 d and 32.5 ± 17.9 d for the control group (P < 0.001), and morbidity related to nutritional support was 8.6% and 42.5%, respectively (P < 0.01). In patients with colonic fistulas, complete closure occurred 23.5 ± 19.5 d after the first application of fibrin glue, and spontaneous closure was observed after 36.2 ± 22.8 d in the control group (P = 0.36). Recurrences were observed in 2 patients because of residual disease. One patient of each group died during follow-up as a consequence of septic complications related to parenteral nutrition. CONCLUSION: Closure time was significantly reduced with the use of fibrin sealant, and oral feeding was resumed faster. We suggest the use of fibrin sealant for the management of stable enterocutaneous fistulas.

关键词： Enterocutaneous fistulas Fibrin sealant Spontaneous closure

Molecular and Serological Epidemiology of Foot-and-Mouth Disease Virus in North Region of Cameroon

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Advances in Microbiology 2022年第10期12卷 579-595页

作者： Simon Jumbo Dickmu Julius Awah-Ndukum Niba Tatanja Aziwo Silas Lendzele Sevidzem Mohamed Moctar Mouliom Mouiche Carla Bravo de Rueda Labib Bakkali Kassimi abel Wade Rebecca Garabed Abdul-Dahiru El-Yuguda Luis Rodriguez Saka Saheed Baba Laboratoire National Vétérinaire LANAVET Garoua Cameroon Department of Animal Production Technology College of Technology The University of Bamenda Bamenda Cameroon Institute of Research in Tropical Ecology (IRET) Libreville Gabon Ecole des Sciences et de Médecine Vétérinaire Université de Ngaoundéré Ngaoundere Cameroon Foreign Animal Disease Research Unit United States Department of Agriculture Agricultural Research Service Plum Island Animal Disease Centre Greenport USA Agence Nationale de Sécurité Sanitaire de l’Alimentation de l’Environnement et du Travail Pierre et Marie Curie Maisons-Alfort France Department of Veterinary Preventive Medicine The Ohio State University Columbus USA Department of Veterinary Microbiology and Parasitology Faculty of Veterinary Medicine University of Maiduguri Maiduguri Nigeria

The serological prevalence of foot and mouth disease virus (FMDV) among the cattle population in the North region of Cameroon was determined using ELISA (Enzyme Linked Immunosorbent Assays) serological tests for structural as well as non-structural proteins. In these cattle, FMDV RNA was identified, amplified, sequenced and the sequences were used to construct a phylogenetic tree. A sedentary cattle population randomly selected from six veterinary centres in the North region was sampled twice, six months apart. High prevalence of FMDV antibody was recorded in the first (402/466 (85.84%)) and second (358/411 (86.90%)) sampling periods. There was no significant difference (P > 0.05) in prevalence of FMDV antibody between the two sampling periods. Goudali and Peulh breeds of cattle and animals of three to five years old were the most infected with FMDV and mostly in the months of May and August. A seroprevalence of 100% (n = 14) of FMDV against serotypes A and O was observed in sera from convalescent animals in the study area. FMDV antigen detection ELISA showed a prevalence of 18/37 (48.65%) for serotypes SAT1 (8.1%), SAT2 (35.1%), A (10.8%) and O (2.7%) among the clinically infected animals. There was no significant difference (P > 0.05) in prevalence of FMDV RNA between the sampling periods. A prevalence of FMDV RNA (17.5% (n = 120) and 16.7% (n = 240)) was observed among the sedentary animals that were sampled four to five months apart. FMDV RNA prevalence of 28/37 (75.6%) among clinically infected animals was also observed, thus confirming all the 12 outbreaks investigated. Sequence analysis of VP1 coding gene of the SAT2 serotype showed that it was homologous to the Libyan isolates (that caused epidemics in northern Africa in 2012) and also clustered with the serotypes isolated from both Nigeria and Sudan in 2007.

关键词： Foot-and-Mouth Disease Seroprevalence Non-Structural Protein Structural Protein ELISA Sedentary Cattle North Cameroon

疱疹病毒性脑炎人类遗传免疫缺陷机制研究:Toll样受体3诱导性免疫反应的重要作用

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疱疹病毒性脑炎人类遗传免疫缺陷机制研究:Toll样受体3诱导性免疫...

Clinical and Therapeutic Evaluation of Hypertensives According to the Practice of Ambulatory Blood Pressure Measurement (ABPM) at the Bel Air International Clinic in Conakry from January 1, 2019 to November 30, 2022

中华医学会全国第九次感染病学学术会议

作者： Emmanuelle JOUANGUY Laurent abel Jean-Laurent CASANOVA 张申英张欣欣 Laboratoire de Génétique Humaine des Maladies Infectieuses Université de Paris René Descartes-INSERM U550Faculté de Médecine NeckerParis 75015 France 上海瑞金医院中法基因组与生命科学合作研究中心

I型单纯疱疹病毒(Herpes simplex virus 1,HSV-1)是一个人群广泛易感的病毒,全球约80％的青年人群受HSV-1感染但绝大部分临床表现轻微甚至缺如。疱疹病毒性脑炎(Herpes simplex encephalitis, HSE)是由HSV-1在少数人(发病率约1／250,000...

I型单纯疱疹病毒(Herpes simplex virus 1,HSV-1)是一个人群广泛易感的病毒,全球约80％的青年人群受HSV-1感染但绝大部分临床表现轻微甚至缺如。疱疹病毒性脑炎(Herpes simplex encephalitis, HSE)是由HSV-1在少数人(发病率约1／250,000)所引起的罕见的严重HSV-1感染,在阿昔洛维用于治疗前,HSE病人的死亡率约为70％,且治愈病人大多伴有严重后遗症。

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World Journal of Cardiovascular Diseases 2023年第6期13卷 327-332页

作者： Alpha Kone Fousseny Diakite abel Mansaré Mahamoud Sama Cherif Mamadou Bassirou Bah Sana Samoura Souleymane Diakité Ibrahima Sory Barry Ibrahima Sory Sylla Elhadji Yaya Baldé Abdoulaye Bangoura Mariame Beavogui Mamadou Dadhi Baldé Mohamed Lamine Kaba Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Bel Air International Clinic CIBA Conakry Guinea Cardiology Department of Sino-Guinean Hospital Conakry Guinea Donka National Hemodialysis Center Conakry Guinea Cardiology Department of National Hospital Ignace Deen Conakry Guinea

Introduction: Ambulatory Blood Pressure Measurement (ABPM) is a non- invasive examination recommended for subjects at high cardiovascular risk, and those requiring a nocturnal drop in BP such as elderly and obese subjects, those with secondary hypertension or resistant, diabetics, subjects with metabolic syndrome or sleep apnea syndrome. The objective of this study was to evaluate the contribution of ABPM in the diagnosis and evaluation of the level of control of hypertension under treatment at the Bel Air international clinic. Materials and Methods: This is a retrospective, cross-sectional and descriptive study, carried out at the Bel Air International Clinic in Conakry (Guinea) between January 2019 and November 30, 2022. It included a consecutive series of 180 consenting patients recruited through an ambulatory measurement of 24-hour blood pressure from a FUGADA brand device. Results: We collected 180 patients, with a male predominance (sex-ratio M/F = 2.46). The mean age of the patients was 48.48 ± 14.23 years. The most represented age group was that of 32 to 42 years with 50 cases (27.8%) followed by that of 43 to 52 years with 42 cases or 23.3%. The indication was for diagnostic purposes in 106 cases 58.9%, the therapeutic evaluation in 58 patients (32.2%). The examination was prescribed by a cardiologist in 98 cases (54.4%), a general practitioner in 71 cases (39.4%), a neurologist in 11 cases (6.1%). In the therapeutic evaluation, high blood pressure was controlled in 24 patients (13.3%) and uncontrolled in 34 cases (18.9%). In the diagnostic indication, high blood pressure was confirmed in 79 cases (43.9%) with a statistically significant link (Chi2 = 4.57 and p-value = 0.032). The nycthemeral mean was 187.27 ± 26.22 mmHg for systolic blood pressure (SBP) and 110.37 ± 19.06 mmHg for diastolic blood pressure (DBP), during the day, 151.64 ± 21.45 mmHg for SBP and 71.59 ± 8.67 mmHg for diastolic blood pressure. During the study 65 patients (36.1%) were id

关键词： Ambulatory Blood Pressure Measurement Guinea

Chemical Characterization and Cytotoxic Activity of Antarctic Macroalgae Extracts against Colorectal Cancer

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Advances in Biological Chemistry 2019年第5期9卷 167-177页

作者： Rafaele Frassini Yeslei Paulino da Silva Sidnei Moura Leonardo Zambotti Villela Aline Paternostro Martins Pio Colepicolo Mutue Toyota Fujii Nair S.Yokoya Claudio Martin Pereira de Pereira Vagner Reinaldo Zingalli Bueno Pereira Joao Antonio Pegas henriques Mariana Roesch-Ely Laboratory of Genomics Proteomics and DNA RepairUniversity of Caxias do SulCaxias do SulRSBrazil Laboratory of Biosynthetic and Natural Products of Caxias do Sul Caxias do SulRSBrazil Laboratory of Biochemistry and Molecular Biology of Algae University of Sao PauloSao PauloSPBrazil Phycologycal Research Institute of BotanySao PauloSPBrazil Laboratory of Lipidomics and Biorganic—LLipidomicaBio Federal University of PelotasPelotasRSBrazil General Hospital University of Caxias do SulCaxias do SulRSBrazil

Background/Aim: Antarctic seaweeds are considered a promising source of compounds with anticancer activity. Colorectal cancer (CRC) is one of the most incident cancers with high mortality rates worldwide. This work aimed to characterize chemically extracts of the Antarctic macroalgae Iridaea cordata, Cystosphaera jacquinotii and Desmarestia anceps and to evaluate the cytotoxic effects against human colon cancer HCT 116 cell line. Materials and Methods: The extracts were obtained by depletion using an ultrasound probe and were identified by High-Performance Liquid Chromatography (HPLC) and Gas Chromatography coupled with Mass Spectrometry (GC-MS). Cell viability was determined by MTT assay. Results: Hexanic and chloroform extracts of the I. cordata and the hexanic, chloroform and methanolic extracts of D. anceps were able to inhibit growth of colorectal cancer cells in the three different incubation times (24, 48 and 72 h). Through GC analysis, 01 compounds were identified in the hexane extract and 02 compounds in the chloroform extract of the algae I. cordata. The hexane extract of D. anceps macroalgae presented 5 compounds, chloroform extract 10 and methanolic extract 3 respectively, with special highlight to fucosterol. Carotenoid analysis by HPLC identified β-carotene in all species, while zeaxanthin was present in the spectrum of I. cordata and C. jacquinotii. Fucoxanthin and violaxanthin were confirmed in the brown seaweeds C. jacquinotii and D. anceps. Conclusion: Extracts of macroalgae I. Cordata and D. anceps may be a source of therapeutic agents against CRC.

关键词： Antarctic Seaweeds Antitumor Activity Colorectal Cancer