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Soft Na.oscience Letters 2012年第3期2卷 41-45页

作者： Smita.a.a.na.h Moha.ma. a. Hussa.n Vidya.a.d Na.jundia. a. k. sood Depa.tment of Biotechnology PA College of Engineering Mangalore India Depa.tment of Molecula. Reproduction Development and Genetics Indian Institute of Science Bangalore India Depa.tment of Physics Indian Institute of Science Bangalore India

We show tha. the cytotoxic effect of ca.bon na.otubes (CNTs) on ba.teria.is media.ed by mecha.ica. da.a.e to the cell wa.l a.d membra.e. Two β-ga.a.tosida.e-producing stra.ns of Escherichia.coli ha.boringgenomica.ly integra.ed reporter gene constructs, na.ely pchbB:la.Za.d prpoS:la.Z, were used for the purpose. We first verified tha. CNTs result in a. inhibition of cell growth. Enzyme a.tivity wa. determined using a.reporter gene a.sa. in which CNTs were used without the lysis buffer (conta.ning detergent). β-ga.a.tosida.e a.tivity in the presence of CNTs a.one mea.ured severa. fold more tha. the controls used (without na.otubes). This suggests tha. CNTs da.a.e the cell membra.e in a.ma.ner simila. to the detergent in the lysis buffer a.d render E. coli cell wa.ls porous, ca.sing cell contents including enzymes to lea. out into the medium. Our results support the hypothesis tha. mecha.ica. da.a.e to ba.teria. cell membra.es is the preva.ling ca.se of CNT-cytotoxicity.

关键词： Ca.bon Na.otubes Cytotoxicity Membra.e Da.a.e Microbia. Stra.ns Reporter Genea.sa.

Photon orbits a.d pha.e tra.sition for Letelier a.S bla.k.holes immersed in perfect fluid da.k.ma.ter

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Chinese Physics C 2024年第6期48卷 247-259页

作者： a.hima.sood Md Sa.ir a.i J.k.Singh Susha.t G.Ghosh Depa.tment of Ma.hema.ics Netaji Subhas University of TechnologyNew Delhi-110078India Centre for Theoretica. Physics Jamia Millia IslamiaNew Delhi 110025India Depa.tment of Physics Mahishadal Raj CollegePurba MedinipurWest Bengal721628India Institute of Theoretica. Physics&Resea.ch Center of Gra.ita.ion Lanzhou UniversityLanzhou 730000China k.y La.ora.ory of Qua.tum Theory a.d a.plica.ions of MoE Lanzhou UniversityLanzhou 730000China La.zhou Center for Theoretica. Physics&k.y La.ora.ory of Theoretica. Physics of Ga.su Province Lanzhou UniversityLanzhou 730000China a.trophysics a.d Cosmology Resea.ch Unit School of MathematicsStatistics and Computer ScienceUniversity of KwaZulu-NatalPrivate Bag X54001Durban 4000South Africa

We obta.n a. exa.t solution for spherica.ly symmetric Letelier a.S bla.k.holes immersed in perfect fluid da.k.ma.ter(PFDM).Considering the cosmologica. consta.t a. the positive pressure of the system a.d volume a. its conjuga.e va.ia.le,we a.a.yze the thermodyna.ics of our bla.k.holes in the extended pha.e *** to the ba.k.round clouds of strings pa.a.eter(a.a.d the pa.a.eter endowed with PFDM(β),we a.a.yze the Ha.k.ng tempera.ure,entropy,a.d specific ***,we investiga.e the rela.ionship between the photon sphere ra.ius a.d pha.e tra.sition for the Letelier a.S bla.k.holes immersed in *** the a.a.ysis,with a.pa.ticula. condition,non-monotonic beha.iors a.e found between the photon sphere ra.ius,impa.t pa.a.eter,PFDM pa.a.eter,tempera.ure,a.d *** ca. rega.d the cha.ges in both the photon sphere ra.ius a.d impa.t pa.a.eter before a.d a.ter pha.e tra.sition a. the order pa.a.eter;their critica. exponents nea. the critica. point a.e equa. to the sa.e va.ue,1/2,simila. to tha. in ordina.y therma. *** indica.es tha. a.universa. rela.ion of gra.ity ma. exist nea. the critica. point for a.bla.k.hole thermodyna.ic system.

关键词： a.S bla.k.holes perfect fluid da.k.ma.ter Letelier spa.etime photon orbit extended pha.e spa.e thermodyna.ics correla.ion of photon orbit a.d thermodyna.ics

GUa.DIa.: a.Multi-Tiered Defense a.chitecture for Thwa.ting Prompt Injection a.ta.k. on LLMs

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Journa. of Softwa.e Engineering a.d a.plica.ions 2024年第1期17卷 43-68页

作者： Pa.ija. Ra. Sa.mil sood Vija. k. Ma.isetti a.shdeep Ba.ga School of Computer Science Engineering & Technology Bennett University Greater Noida India School of Cybersecurity a.d Priva.y Georgia Institute of Technology Atlanta USA Cloudemy Technology La.s Chandigarh India

This pa.er introduces a.novel multi-tiered defense a.chitecture to protect la.gua.e models from a.versa.ia. prompt a.ta.k.. We construct a.versa.ia. prompts using stra.egies lik. role emula.ion a.d ma.ipula.ive a.sista.ce to simula.e rea. threa.s. We introduce a.comprehensive, multi-tiered defense fra.ework.na.ed GUa.DIa. (Gua.dra.ls for Upholding Ethics in La.gua.e Models) comprising a.system prompt filter, pre-processing filter levera.ing a.toxic cla.sifier a.d ethica. prompt genera.or, a.d pre-displa. filter using the model itself for output screening. Extensive testing on Meta.s Lla.a.2 model demonstra.es the ca.a.ility to block.100% of a.ta.k.prompts. The a.proa.h a.so a.to-suggests sa.er prompt a.terna.ives, thereby bolstering la.gua.e model security. Qua.tita.ively eva.ua.ed defense la.ers a.d a. ethica. substitution mecha.ism represent k.y innova.ions to counter sophistica.ed a.ta.k.. The integra.ed methodology not only fortifies sma.ler LLMs a.a.nst emerging cyber threa.s but a.so guides the broa.er a.plica.ion of LLMs in a.secure a.d ethica. ma.ner.

关键词： La.ge La.gua.e Models (LLMs) a.versa.ia. a.ta.k Prompt Injection Filter Defense a.tificia. Intelligence Ma.hine Lea.ning Cybersecurity

a.esthetic considera.ion in Meigs syndrome with la.ge pleura. effusion a.d lung colla.se

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Journa. of a.ute Disea.e 2024年第1期13卷 43-44,I0006,I0007页

作者： Sha.endra.Singh Deepa. Mishra.Deepu k.Peter Munish sood Depa.tment of a.a.sthesiology a.d Critica. Ca.e Command Hospital(NC)UdhampurIndia Depa.tment of a.a.sthesiology a.d Critica. Ca.e Command Hospital(SC)PuneIndia Depa.tment of Pulmona.y Medicine Command Hospital(NC)UdhampurIndia Depa.tment of Orthopa.dics INHSMumbaiIndia

Meigs syndrome(MS)is cha.a.terized by a.benign ova.ia. tumor(fibroma.,hydrothora. on the right side,a.d a.cites;which ca. be resolved perma.ently a.ter *** litera.ure revea.s tha. most MS surgeries were performed under genera. a.esthesia.Ga.[1].However,Ga.poses ma.or risk. to the *** the high risk.of ga.tric content regurgita.ion,poor genera. condition or dyselectrolytemia.ma. lea. to dela.ed a.ousa.,a.d a.socia.ed multi-orga. *** mecha.ica. ventila.ion is a.so difficult due to a.cites a.d hydrothora.(reduced ca.dia. output,impa.red ventila.ion-perfusion in lungs ca.sing hypoxia.a.d hyperca.nia.[1,2].In this letter,we report a.ca.e of MS tumor resection under the suba.a.hnoid block.Sa.)to mitiga.e these issues a.d a.so review the complica.ions a.socia.ed with both techniques.

关键词： a.esthesia impa.red a.cites

Eva.ua.ing Priva.y Lea.a.e a.d Memoriza.ion a.ta.k. on La.ge La.gua.e Models (LLMs) in Genera.ive a. a.plica.ions

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Journa. of Softwa.e Engineering a.d a.plica.ions 2024年第5期17卷 421-447页

作者： Ha.shva.dha. a.itya.Sidda.sh Cha.la.Gunik.0}Dhingra.Pa.ija. Ra. Sa.mil sood Ta.ma. Singh Zeba.Mohsin Wa.e a.shdeep Ba.ga.Vija. k. Ma.isetti School of Computer Science Engineering & Technology Bennett University Greater Noida India Cloudemy Technology La.s Chandigarh India School of Cybersecurity a.d Priva.y Georgia Institute of Technology Atlanta USA

The recent interest in the deployment of Genera.ive a. a.plica.ions tha. use la.ge la.gua.e models (LLMs) ha. brought to the forefront significa.t priva.y concerns, nota.ly the lea.a.e of Persona.ly Identifia.le Informa.ion (PII) a.d other confidentia. or protected informa.ion tha. ma. ha.e been memorized during tra.ning, specifica.ly during a.fine-tuning or customiza.ion process. We describe different bla.k.box a.ta.k. from potentia. a.versa.ies a.d study their impa.t on the a.ount a.d type of informa.ion tha. ma. be recovered from commonly used a.d deployed LLMs. Our resea.ch investiga.es the rela.ionship between PII lea.a.e, memoriza.ion, a.d fa.tors such a. model size, a.chitecture, a.d the na.ure of a.ta.k. employed. The study utilizes two broa. ca.egories of a.ta.k.: PII lea.a.e-focused a.ta.k. (a.to-completion a.d extra.tion a.ta.k.) a.d memoriza.ion-focused a.ta.k. (va.ious membership inference a.ta.k.). The findings from these investiga.ions a.e qua.tified using a. a.ra. of eva.ua.ive metrics, providing a.deta.led understa.ding of LLM vulnera.ilities a.d the effectiveness of different a.ta.k..

关键词： La.ge La.gua.e Models PII Lea.a.e Priva.y Memoriza.ion Overfitting Membership Inference a.ta.k.(MIa.

a.ra.domized controlled tria. on tria.cinolone versus sa.ine impregna.ed merocel post endoscopic sinus surgery:Our experience in a.tertia.y ca.e centre

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World Journa. of Otorhinola.yngology-Hea. a.d Neck.Surgery 2024年第3期10卷 193-199页

作者： a.a.ya.sood k.ushboo Goel SSa.jeev Bha.a. Dimple Sa.ni Dinesh k.ma. Sha.ma.Visha. Ya.a. Depa.tment of Otorhinola.yngology a.d Hea.&Neck.Surgery Government Medical CollegePatialaPunjabIndia

Purpose:To a.sess the potentia. benefit of impregna.ing Merocel(a.non-a.sorba.le na.a. dressing)with a.topica. steroid solution,for use a. a.direct a.d slow loca. delivery system of steroids a.ter sinus surgery to improve postopera.ive wound ***:In this ra.domized controlled tria.,40 pa.ients with bila.era. chronic rhinosinusitis with na.a. polyposis were subjected to functiona. endoscopic sinus *** the completion of the surgery,Merocel pa.k. were inserted in the bila.era. na.a. ca.ities a.d infiltra.ed with 4 mL tria.cinolone(40 mg/mL)in one na.a. ca.ity(trea.ment group)a.d 4 mL norma. sa.ine in the other(control group).Na.a. pa.k. were removed on the third postopera.ive da. a.d postopera.ive hea.ing a.sessment wa. done on postopera.ive Week. 1,2,4,a.d *** findings were noted a. per Lund k.nnedy(Lk.S)a.d periopera.ive sinus endoscopy(POSE)scores a.d compa.ed on both ***:Significa.t(Pa. noted in Lund k.nnedy score for crusting a.d polyp a. Week.12,for edema.a. Week.1,a.d na.a. discha.ge a. Week. 1 a.d 12,but there wa. no significa.t improvement in sca.ring a. a.y ***,the difference between the trea.ment a.d control a.ms wa. sta.istica.ly significa.t a. a.l postopera.ive visits except a. Week.***,there wa. a.significa.t improvement in POSE scores a. Week. 1,2,a.d 12 but not a. Week.***:This study positively concludes tha. the na.a. ca.ity pa.k.d with drug-soa.ed pa.k. ha. less sca.ring a.d edema.in the postopera.ive period a.d the overa.l wound hea.ing wa. much better a. compa.ed to sa.ine-soa.ed pa.k..

关键词： chronic rhinosinusitis functiona. endoscopic sinus surgery Lund k.nnedy merocele periopera.ive sinus endoscopy tria.cinolone

Comprehensive a.a.ysis of uncerta.nty qua.tifica.ion for the^(58)Ni(n,p)^(58)Co rea.tion cross section

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Chinese Physics C 2024年第9期48卷 170-175页

作者： Ma.esh Choudha.y a.a. Sha.ma.Na.ra.a.Singh Ma.ima.Upa.hya. Punit Dubey a.Ga.dhi a.a.h Hingu G Mishra.Suk.0}ya.De L.S.Da.u a.a. k.ma. R.G.Thoma. Sa.ra. sood Sa.in Pra.a. S.Muk.erjee I.N.Rusk.v Yu.N.k.pa.ch a.k.ma. Depa.tment of Physics Banaras Hindu UniversityVaranasi 221005India Horia.Hulubei Na.iona. Institute of Physics a.d Nuclea. Engineering-IFIN-HH Bucharest 077125Romania Depa.tment of Physics The Maharaja Sayajirao University of BarodaVadodara 390002India Nuclea. Physics Division Bhabha Atomic Research CentreMumbai 400085India Hea.th Physics Division Bhabha Atomic Research CentreMumbai 400085India Depa.tment of Electrica. Power Engineering Brno University of TechnologyBrno 61600Czech Republic Institute for Nuclea. Resea.ch a.d Nuclea. Energy Bulgarian Academy of SciencesSofia 1784Bulgaria Joint Institute for Nuclea. Resea.ch(JINR) Dubna 141980Russia

In this study,we mea.ured the^(58)Ni(n,p)^(58)Co rea.tion cross section with neutron energies of 1.06,1.86,a.d 2.85 *** cross section wa. mea.ured using neutron a.tiva.ion techniques a.dγ-ra. spectroscopy,a.d it wa. compa.ed with cross section da.a.a.a.la.le in the ***,we ca.cula.ed the cova.ia.ce ma.rix of the mea.ured cross section for the a.orementioned nuclea. *** uncerta.nties of the theoretica. ca.cula.ion for^(58)Ni(n,p)^(58)Co rea.tion cross section were ca.cula.ed via.Monte Ca.lo *** this study,we used uncerta.nties in the optica. model a.d level density pa.a.eters to ca.cula.e uncerta.nties in the theoretica. cross *** theoretica. ca.cula.ions were performed by using *** this study,we a.m to a.a.yze the effect of uncerta.nties of the nuclea. model input a. well a. different experimenta. va.ia.les used to obta.n the va.ues of rea.tion cross section.

关键词： ^(58)Ni(n p)^(58)Co rea.tion γ-ra. spectroscopy uncerta.nty qua.tifica.ion of cross section cova.ia.ce a.a.ysis

Investiga.ion of 58Ni(n, p)58Co rea.tion cross-section with cova.ia.ce a.a.ysis

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Chinese Physics C 2024年第2期48卷 78-90页

作者： a.a.h Hingu S.Muk.erjee Siddha.th Pa.a.ha.i a.ora.Sa.geeta.a.Ga.dhi Ma.ima.Upa.hya. Ma.esh Choudha.y Sumit Ba.a. Na.ra.a.Singh G.Mishra.Suk.0}ya.De Sa.ra. sood Sa.in Pra.a. G.Sa.ena.a.a. k.ma. R.G.Thoma. B.k.a.ra.a. k.k.0}ovsk. a.k.ma. Depa.tment of Physics Faculty of ScienceThe M.S.University of BarodaVadodara 390002India Fa.ulty of Electrica. Engineering a.d Communica.ion Brno University of TechnologyBrnoCzech Republic Depa.tment of Physics Faculty of ScienceUniversity of ZagrebBijenička c.32Zagreb 10000Croatia Depa.tment of Physics University Institute of SciencesChandigarh UniversityGharuanMohali 140413PunjabIndia Depa.tment of Physics Banaras Hindu UniversityVaranasi 221005India Horia.Hulubei Na.iona. Institute for Physics a.d Nuclea. Engineering Măgurele 077125Romania Nuclea. Physics Division Bhabha Atomic Research CentreMumbai 400085India Hea.th Physics Division Bhabha Atomic Research CentreMumbai 400085India Depa.tment of Physics(H&S) Government Women Engineering CollegeAjmer 305002India Sa.a.Institute of Nuclea. Physics Kolkata 700064India Homi Bha.ha.Na.iona. Institute Anushakti NagarMumbai 400094India

The excita.ion function of the 58Ni(n,p)58Co rea.tion wa. mea.ured using the well-esta.lished neutron a.tiva.ion technique a.dγ-ra. *** in the energy ra.ge of 1.7 to 2.7 MeV were genera.ed using the 7Li(p,n)*** neutron flux wa. mea.ured using the sta.da.d 115In(n,n’)115mIn monitor *** results of the neutron spectrum a.era.ed cross-section of 58Ni(n,p)58Co rea.tions were compa.ed with existing cross-section da.a.a.a.la.le in the EXFOR da.a.libra.y a. well a. with va.ious eva.ua.ed da.a.libra.ies such a. ENDF/B-VIII.0,JEFF-3.3,JENDL-4.0,a.d *** ca.cula.ions were performed using the nuclea. rea.tion code *** nuclea. level density(NLD)models were tested,a.d their results were compa.ed with the present *** NLDs were a.so obta.ned through the spectra. distribution method(SDM).The cross-section results,a.ong with the a.solute errors,were obta.ned by investiga.ing the uncerta.nty propa.a.ion a.d using the cova.ia.ce *** forγ-ra. true coincidence summing,low-energy ba.k.round neutrons,a.dγ-ra. self a.tenua.ion were *** experimenta. cross-section obta.ned in the present study is consistent with previously published experimenta. da.a.eva.ua.ed libra.ies,a.d theoretica. ca.cula.ions ca.ried out using the Ta.YS code.

关键词： nuclea. rea.tions (n,p)rea.tion cross-section mea.urement cova.ia.ce a.a.ysis nuclea. level density

Surfa.e roughness mea.urements in NFMQL a.sisted turning of tita.ium a.loys: a. optimiza.ion a.proa.h

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Friction 2017年第2期5卷 155-170页

作者： Munish k.GUPTa.P.k.sood MED NIT Hamirpur(H.P.)177005 India

The prediction a.d optimiza.ion of surfa.e roughness va.ues rema.n a.critica. concern in na.o-fluids ba.ed minimum qua.tity lubrica.ion (NFMQL) turning of tita.ium (gra.e-2) ***,we discuss a. a.plica.ion of response surfa.e methodology with Box-Cox tra.sforma.ion to determine the optima. cutting pa.a.eters for three surfa.e roughness va.ues,i.e.,Ra.Rq,a.d Rz,in turning of tita.ium a.loy under the NFMQL *** surfa.e roughness prediction model ha. been esta.lished ba.ed on the selected input pa.a.eters such a. cutting speed,feed ra.e,a.proa.h a.gle,a.d different na.o-fluids *** the multiple regression technique is used to find the rela.ionship between the given responses a.d input ***,the experimenta. da.a.were optimized through the desira.ility function *** findings from the current investiga.ion showed tha. feed ra.e is the most effective pa.a.eter followed by cutting speed,different na.o-fluids,a.d a.proa.h a.gle on Ra.a.d Rq va.ues,wherea. cutting speed is more effective in the ca.e of Rz under NFMQL ***,the predicted results a.e compa.a.ively nea. to the experimenta. va.ues a.d hence,the esta.lished models of RSM using Box-Cox tra.sforma.ion ca. be used for prediction sa.isfa.torily.

关键词： na.o-fluids optimiza.ion surfa.e roughness turning tita.ium a.loy

Hepa.ocellula. ca.cinoma.review:Current trea.ment,a.d evidence-ba.ed medicine

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World Journa. of Ga.troenterology 2014年第15期20卷 4115-4127页

作者： a.i Ra.a.Ga.a. k.sood Depa.tment of Interna. Medicine St. Luke’s Episcopal HospitalBaylor College of MedicineHoustonTX 77030United States Division of Ga.troenterology a.d Hepa.ology Baylor College of MedicineSt. Luke’s Liver CenterHoustonTX 77030United States

Hepa.ocellula. ca.cinoma.HCC)is the fifth most common tumor *** trea.ment options a.e a.a.la.le for HCC including cura.ive resection,liver tra.spla.ta.ion,ra.iofrequency a.la.ion,tra.s-a.teria. chemoemboliza.ion,ra.ioemboliza.ion a.d systemic ta.geted a.ent lik. *** trea.ment of HCC depends on the tumor sta.e,pa.ient performa.ce sta.us a.d liver function reserve a.d requires a.multidisciplina.y *** the pa.t few yea.s with significa.t a.va.ces in surgica. trea.ments a.d locoregiona. thera.ies,the short-term surviva. of HCC ha. improved but the recurrent disea.e rema.ns a.big *** pa.hogenesis of HCC is a.multistep a.d complex process,wherein a.giogenesis pla.s a. importa.t *** pa.ients with a.va.ced disea.e,sora.enib is the only a.proved thera.y,but novel systemic molecula. ta.geted a.ents a.d their combina.ions a.e *** a.ticle provides a. overview of trea.ment of ea.ly a.d a.va.ced sta.e HCC ba.ed on our extensive review of releva.t litera.ure.

关键词： Hepa.ocellula. ca.cinoma Tra.s-a.teria. chemoemboliza.ion Drug-eluting bea.s Ra.iofrequency a.la.ion Liver tra.spla.ta.ion Chemothera.y Sora.enib Ra.ioemboliza.ion