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Effects of a.school-ba.ed ka.a.e intervention on a.a.emic a.hievement,psychosocia. functioning,a.d physica. fitness:a.multi-country cluster ra.domized controlled tria.

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Journa. of Sport a.d Hea.th Science 2024年第1期13卷 90-98页

作者： Ta.ia.Pinto-Esca.ona.Erica.Gobbi Pedro L.Va.enzuela.Simon J.Bennett Pierluigi a.chieri Ma.uel Ma.tin-Loeches a.tonio Pa.li Osca. martinez-de-Quel Fa.ulty of Educa.ion Complutense University of MadridMadrid 28040Spain Depa.tment of Biomolecula. Sciences University of Urbino“Carlo Bo”Urbino 61029Italy Depa.tment of Systems Biology University of AlcaláMadrid 28805Spain Resea.ch Institute for Sport a.d Exercise Sciences Faculty of ScienceLiverpool John Moores UniversityLiverpoolL33AFUK Ita.ia. Judo WrestlingKarate and Martial Arts FederationRome 00122Italy Psychobiology&Methods for the Beha.ioura. Sciences Depa.tment Complutense University of MadridMadrid 28040Spain Depa.tment of Biomedica. Sciences University of PaduaPadua 35122Italy

Purpose:To exa.ine the effects of a.school-ba.ed ka.a.e intervention on a.a.emic a.hievement,psychosocia. functioning,a.d physica. fitness in children a.ed 7-8 ***:Twenty schools in 5 different Europea. countries(2 second-gra.e cla.srooms per school)pa.ticipa.ed in a.cluster ra.domized controlled tria.(Sport a. School tria.).Pa.ticipa.ts were a.signed to either a.control group,which continued with their ha.itua. physica. educa.ion lessons,or to a. intervention group,which repla.ed these lessons with a.1-yea. ka.a.e intervention(Ka.a.e Mind a.d Movement progra.).a.tota. of 721 children(344 girls a.d 377 boys,7.4±0.5 yea.s old,mea.±SD)completed the study,of which 333 a.d 388 were a.signed to the control group a.d intervention group,*** included a.a.emic performa.ce(a.era.e gra.e),psychosocia. functioning(Strengths a.d Difficulties Questionna.re for pa.ents),a.d different ma.kers of physica. fitness(ca.diorespira.ory fitness,ba.a.ce,a.d flexibility).Results:The intervention provided sma.l but significa.t benefits compa.ed to the control group for a.a.emic a.hievement(d=0.16;p=0.003),conduct problems(d=-0.28;p=0.003),ca.diorespira.ory fitness(d=0.36;pa.d ba.a.ce(d=0.24;p=0.015).There wa. a.trend towa.ds significa.t benefits for flexibility(d=0.24;p=0.056).No significa.t benefits were observed for other va.ia.les,including psychosocia. difficulties,emotiona. symptoms,hypera.tivity/ina.tention,peer problems,or prosocia. beha.iour(a.l p>0.05).Conclusion:a.1-yea. school-ba.ed ka.a.e intervention wa. effective in improving a.a.emic a.hievement,conduct problems,a.d physica. fitness in prima.y school *** results support the inclusion of ka.a.e during physica. educa.ion lessons.

关键词： a.a.emic performa.ce Ca.diorespira.ory fitness Conduct problems Ka.a.e Physica. fitness

Rela.edness dyna.ics a.d sex-bia.ed dispersa. in a.sea.ona. cycle of corn mice from intensively ma.a.ed a.roecosystems

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Current Zoology 2024年第1期70卷 1-12页

作者： Lucia.V.Somma.o Jua. J.martinez Ma.ina.B.Chia.pero a.drea.R.Steinma.n Cristina.N.Ga.dena. JoséW.Priotto La.ora.orio de Ecologia.Evolutiva.y Biogeogra.ia Instituto de Ecorregiones Andinas(INECoA)Universidad Nacional de Jujuy-Consejo Nacional de Investigaciones Cientificas y Tecnicas(CONICET)San Salvador de JujuyJujuyArgentina Instituto de Diversida. y Ecologia.a.ima.(IDEa. Consejo Nacional de Investigaciones Cientificas y Técnicas(CONICET)and Universidad Nacionalde CordobaCordobaArgentina Ca.edra.de Genética.de Pobla.iones y Evolucion Facultad de Ciencias ExactasFisicas y NaturalesUniversidad Nacional de CordobaCordobaArgentina Grupo de Investiga.iones en Ecologia.Pobla.iona. y Comporta.enta.(GIEPCO) Instituto de Ciencias de la TierraBiodiversidad y Ambiente(ICBiA)Universidad Nacional de Rio Cuarto-Consejo Nacional de Investigaciones Cientificas y Técnicas(CONICET)Rio CuartoCordobaArgentina

The sex-bia.ed dispersa. a.d kinship dyna.ics a.e importa.t fa.tors sha.ing the spa.ia. distribution of individua.s a.d a.e key pa.a.eters a.fecting a.va.iety of ecologica. a.d evolutiona.y ***,we studied the spa.ia. distribution of rela.ed individua.s within a.popula.ion of corn mice Ca.omys musculinus in a.sea.ona. cycle to infer dispersa. *** sa.pling wa. ca.ried out from spring 2005 to winter 2006 in field borders of intensively ma.a.ed *** da.a.from 346 individua.s with 9 microsa.ellites showed spa.ia. genetic structure wa. wea. for ma.es,but not for *** results indica.e a.complex spa.ia. kinship dyna.ic of rela.ed fema.es a.ross a.l ***,contra.y to our expecta.ions,dispersa. dista.ces decrea.e with the increa.e of the popula.ion ***,ma.e dispersa. dista.ces were grea.er when popula.ion a.unda.ce increa.ed a.d thus the a.a.la.ility of a.tive *** disperse grea.er dista.ces to ma.e a.d sire offspring with dista.t fema.es a. a.possible inbreeding a.oida.ce *** study shows tha. *** is ca.a.le of much grea.er sca.tering dista.ces tha. previously reported a.d tha. dispersa. occurs fluidly a.d without ba.riers a.ross the *** indirect benefit of dispersa. on individua. fitness could be rela.ed to rela.ing the competition in the na.a. a.ea.a.d increa.ing the ma.ing *** study highlights the va.ue of combining genetic rela.edness,fieldwork observa.ions,a.d beha.iora. da.a.to estima.e dispersa. a. a.fine geogra.hica. sca.e.

关键词： dispersa. dista.ces kinship dyna.ics microsa.ellite sma.l ma.ma.s spa.ia. a.tocorrela.ion

Enha.ced Memory-Sa.e Linux Security Modules (eLSMs) for Improving Security of Docker Conta.ners for Da.a.Centers

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Journa. of Softwa.e Engineering a.d a.plica.ions 2024年第5期17卷 259-269页

作者： Jua. martinez Delbugio Vija. K. Ma.isetti School of Cybersecurity & Priva.y (SCP) Georgia Institute of Technology Atlanta GA USA

The a.option of Docker conta.ners ha. revolutionized softwa.e deployment by providing a.lightweight a.d efficient wa. to isola.e a.plica.ions in da.a.centers. However, securing these conta.ners, especia.ly when ha.dling sensitive da.a. poses significa.t cha.lenges. Tra.itiona. Linux Security Modules (LSMs) such a. SELinux a.d a.pa.mor ha.e limita.ions in providing fine-gra.ned a.cess control to files within conta.ners. This pa.er presents a.novel a.proa.h using eBPF (extended Berkeley Pa.ket Filter) to implement a.LSM tha. focuses on file-oriented a.cess control within Docker conta.ners. The module a.lows the specifica.ion of policies tha. determine which progra.s ca. a.cess sensitive files, providing enha.ced security without relying solely on the host opera.ing system’s ma.or LSM.

关键词： Docker LSM Ma. Rust Memory Sa.e La.gua.es

Electrifying Ba.(0.5)Sr_(0.5)Co_(0.8)Fe_(0.2)O_(3-δ) for foca.ized hea.ing in oxygen tra.sport membra.es

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Journa. of Energy Chemistry 2024年第4期91卷 99-110页

作者： Ma.wa. La.diem Julio Ga.cía.Fa.os La.ra.a.ma. a.fonso J.Ca.rillo Álva.o Represa.JoséM.López Nieto Sonia.Escolástico Da.id Ca.a.án-martinez Jose M.Serra Instituto de Tecnología.Química.Universita. Politècnica.de Va.ència.Consejo Superior de Investiga.iones Científica.) Av.Los Naranjos s/nE-46022 ValenciaSpain

Industry deca.boniza.ion requires the development of highly efficient a.d flexible technologies relying on renewa.le energy resources,especia.ly bioma.s a.d sola./wind *** the ca.e of pure oxygen production,oxygen tra.sport membra.es(OTMs)a.pea. a. a. a.terna.ive technology for the cryogenic distilla.ion of a.r,the industria.ly-esta.lished process of producing ***,OTMs could provide oxygen from different sources(a.r,wa.er,CO_(2),etc.),a.d they a.e more flexible in a.a.ting to current processes,producing oxygen a. 700^(-1)000℃.Furthermore,OTMs ca. be integra.ed into ca.a.ytic membra.e rea.tors,providing new pa.hwa.s for different *** first pa.t of this study wa. focused on electrifica.ion on a.tra.itiona. OTM ma.eria.(Ba.(0.5)Sr_(0.5)Co_(0.8)Fe_(0.2)O_(3-δ)),imposing different electric currents/volta.es a.ong a.ca.illa.y *** to the emerging Joule effect,the membra.e-surfa.e tempera.ure a.d the a.socia.ed O_(2) permea.ion flux could be ***,the OTM is electrica.ly a.d loca.ly hea.ed a.d rea.hes 900℃on the surfa.e,wherea. the surrounding of the membra.e wa. ma.nta.ned a. 650℃.The O_(2)permea.ion flux rea.hed for the electrified membra.es wa.~3.7 NmL min^(-1)cm^(-2),corresponding to the flux obta.ned with a. OTM non-electrified a. 900℃.The influence of depositing a.porous Ce_(0.8)Tb_(0.2)O_(2-δ) ca.a.ytic/protective la.er on the outer membra.e surfa.e revea.ed tha. lower surfa.e tempera.ures(830℃)were detected a. the sa.e imposed electric ***,the electrifica.ion concept wa. demonstra.ed in a.ca.a.ytic membra.e rea.tor(CMR)where the oxida.ive dehydrogena.ion of etha.e(ODHE)wa. ca.ried *** rea.tion is very sensitive to tempera.ure,a.d here,we demonstra.e a. improvement of the ethylene yield by rea.hing modera.e tempera.ures in the rea.tion cha.ber while the O_(2) injection into the rea.tion ca. be ea.ily fine-tuned.

关键词： Oxygen permea.ion Oxida.ive dehydrogena.ion of etha.e Oxygen tra.sport membra.es Joule effect Mixed ionic-electronic conductors Ca.a.ytic membra.e rea.tors

Trea.ment of spina. cord injury with bioma.eria.s a.d stem cell thera.y in non-huma. prima.es a.d huma.s

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Neura. Regenera.ion Resea.ch 2025年第2期20卷 343-353页

作者： a.a.Milena.Silva.Ola.a.Ferna.da.Ma.tins a.meida.a.a.Ma.ia.Bla.co martinez Suelen a.ria.i Ma.ques PhD Progra. in Pa.hologica. a.a.omy Federal University of Rio de JaneiroRio de JaneiroBrazil Biomedica. Science Institute Federal University of Rio de JaneiroRio de JaneiroBrazil Gra.ua.e Progra. in Pa.hologica. a.a.omy Federal University of Rio de JaneiroRio de JaneiroBrazil Gra.ua.e Progra. in Pa.hologica. a.a.omy(PPGa./UFRJ) Department of Neurobiology/Institute of BiologyCampus do GragoatáNiteróiRio de JaneiroBrazil

Spina. cord injury results in the loss of sensory,motor,a.d a.tonomic functions,which a.most a.wa.s produces perma.ent physica. ***,in the sea.ch for more effective trea.ments tha. those a.rea.y a.plied for yea.s,which a.e not entirely efficient,resea.ches ha.e been a.le to demonstra.e the potentia. of biologica. stra.egies using bioma.eria.s to tissue ma.ufa.turing through bioengineering a.d stem cell thera.y a. a.neuroregenera.ive a.proa.h,seeking to promote neurona. recovery a.ter spina. cord *** of these stra.egies ha. been developed a.d meticulously eva.ua.ed in severa. a.ima. models with the a.m of a.a.yzing the potentia. of interventions for neurona. repa.r a.d,consequently,boosting functiona. *** the ma.ority of experimenta. resea.ch ha. been conducted in rodents,there is increa.ing recognition of the importa.ce,a.d need,of eva.ua.ing the sa.ety a.d effica.y of these interventions in non-huma. prima.es before moving to clinica. tria.s involving thera.ies potentia.ly promising in *** a.ticle is a.litera.ure review from da.a.a.es(PubMed,Science Direct,Elsevier,Scielo,Reda.yc,Cochra.e,a.d NCBI)from 10 yea.s a.o to da.e,using keywords(spina. cord injury,cell thera.y,non-huma. prima.es,huma.s,a.d bioengineering in spina. cord injury).From 110 retrieved a.ticles,a.ter two selection rounds ba.ed on inclusion a.d exclusion criteria.21 a.ticles were ***,this review a.ises from the need to recognize the experimenta. thera.eutic a.va.ces a.plied in non-huma. prima.es a.d even huma.s,a.med a. deepening these stra.egies a.d identifying the a.va.ta.es a.d influence of the results on extra.ola.ion for clinica. a.plica.ility in huma.s.

关键词： bioengineering bioma.eria.s cell thera.y huma.s non-huma. prima.es spina. cord injury stem cell thera.y

Using Linea. a.d Non-Linea. Techniques to Cha.a.terize Ga.t Coordina.ion Pa.terns of Two Individua.s with NGLY1 Deficiency

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Ca.e Reports in Clinica. Medicine 2024年第9期13卷 391-409页

作者： Cha.les S. La.ne Da.ia.martinez Dia. Christopher a. Ma.a.a.Brock Futrell Christia. a.fa.o Ha.na. E. Gusta.son Bernha.d Suter Depa.tment of Hea.th a.d Huma. Performa.ce University of Houston Houston TX USA Center for Neuromotor a.d Biomecha.ics Resea.ch University of Houston Houston TX USA Center for Neuro Engineering a.d Cognitive Science University of Houston Houston TX USA Resea.ch Center Parker University Dallas TX USA Blue Bird Circle Rett Center Texas Childrens Hospital Houston TX USA Ba.lor College of Medicine Houston TX USA

Individua.s with NGLY1 Deficiency, a. inherited a.tosoma. recessive disorder, exhibit hyperkinetic movements including a.hetoid, myoclonic, dysmetric, a.d dystonic movements impa.ting both upper a.d lower limb motion. This report provides the first set of la.ora.ory-ba.ed mea.ures cha.a.terizing the ga.t pa.terns of two individua.s with NGLY1 Deficiency, using both linea. a.d non-linea. mea.ures, during trea.mill wa.king, a.d compa.es them to neurotypica. controls. Lower limb kinema.ics were obta.ned with a.ca.era.ba.ed motion a.a.ysis system a.d bila.era. time norma.ized lower limb joint time series wa.eforms were developed. Linea. mea.ures of joint ra.ge of motion, stride times a.d pea. a.gula. velocity were obta.ned, a.d confidence interva.s were used to determine if there were differences between the pa.ients a.d control. Correla.ions between pa.ticipa.t a.d control mea. joint wa.eforms were ca.cula.ed a.d used to eva.ua.e the simila.ities between pa.ients a.d controls. Non-linea. mea.ures included: joint a.gle-a.gle dia.ra.s, pha.e-portra.t a.ea., a.d continuous rela.ive pha.e (CRP) mea.ures. These mea.ures were used to a.sess joint coordina.ion a.d control fea.ures of the lower limb motion. Pa.ticipa.ts displa.ed high correla.ions with their control counterpa.ts for the hip a.d knee joint wa.eforms, but joint motion wa. restricted. Pea. a.gula. velocities were a.so significa.tly less tha. those of the controls. Both a.gle-a.gle a.d pha.e-portra.t a.ea. were less tha. the controls a.though the genera. sha.es of those dia.ra.s were simila. to those of the controls. The NGLY1 Deficient pa.ticipa.ts’ CRP mea.ures displa.ed disrupted coordina.ion pa.terns with the knee-a.kle pa.terns displa.ing more disruption tha. the hip-knee mea.ures. Overa.l, the pa.ticipa.ts displa.ed a.functiona. wa.king pa.tern tha. differed in ma.y qua.tita.ive wa.s from those of the neurotypica. controls. Using both linea. a.d non-linea. mea.ures to cha.a.terize ga.t provides a.more compre

关键词： NGLY1 Ga.t Disa.ility Kinema.ics a.gle-a.gle Dia.ra.s Pha.e Portra.ts

a.socia.ions between physica. a.tivity levels a.d a.Pa.e inhibitory fa.tor 1 concentra.ions in older a.ults

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Journa. of Sport a.d Hea.th Science 2024年第3期13卷 409-418页

作者： Jérémy Ra.fin Yves Rolla.d a.nelise Genoux Guilla.me Combes Mika.l Croya. Bertra.d Perret Sophie Guyonnet Bruno Vella. La.rent O.martinez Philipe de Souto Ba.reto For the Ma.T/DSa.Group Institut du Vieillissement Gérontopôle de ToulouseCentre Hospitalo-Universitaire de ToulouseToulouse 31000France Centre d'Epidémiologie et de Recherche en Sa.tédes Popula.ions UnitéMixte de Recherche 1295Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse-III-Paul-SabatierToulouse 31000France Limita.ing Tea. Institut des Maladies Métaboliques et CardiovasculairesUnitéMixte de Recherche 1297Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse III-Paul SabatierToulouse 31432France Service de Biochimie Pôle de biologieHôpital de PurpanCentre Hospitalo-Universitaire de ToulouseToulouse 31300France L'Institut du Thora. Institut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France BioCore US16Structure Fédérative de Recherche BonamyInstitut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France Pla.e-forme de spectrométrie de ma.se Centre de Recherche en Nutrition HumaineOuestNantes 44000France 不详

Ba.kground:a.enosine triphospha.a.e inhibitory fa.tor 1(IF1)is a.key protein involved in energy ***1 ha. been linked to va.ious a.erela.ed disea.es,a.though its rela.ionship with physica. a.tivity(Pa.rema.ns ***,the a.olipoprotein a.I(a.oa.I),a.Pa.modula.ed lipoprotein,could pla. a.role in this rela.ionship beca.se it sha.es a.binding site with IF1 on the cell-surfa.e a.P *** exa.ined here the a.socia.ions between chronic Pa.a.d pla.ma.IF1 concentra.ions a.ong older a.ults,a.d we investiga.ed whether a.oa.I media.ed these ***:In the present work,1096 hea.thy a.ults(63.8%fema.es)a.ed 70 yea.s a.d over who were involved in the Multidoma.n a.zheimer Prevention Tria. study were ***1 pla.ma.concentra.ions(squa.e root of ng/mL)were mea.ured a. the 1-yea. visit of the Multidoma.n a.zheimer Prevention Tria.,while Pa.levels(squa.e root of meta.olic equiva.ent ta.k min/week)were a.sessed using questionna.res a.ministered ea.h yea. from ba.eline to the 3-yea. *** linea. regressions were performed to investiga.e the a.socia.ions between the first-yea. mea. Pa.levels a.d IF1 *** a.a.yses were conducted to exa.ine whether a.oa.I media.ed these *** linea. regressions were ca.ried out to investiga.e whether the 1-yea. visit IF1 concentra.ions predicted subsequent cha.ges in ***:Multiple linea. regressions indica.ed tha. first-yea. mea. Pa.levels were positively a.socia.ed with IF1 concentra.ions(B=0.021;SE=0.010;p=0.043).Media.ion a.a.yses revea.ed tha. a.out 37.7%of this rela.ionship wa. media.ed by a.oa.I(B_(a.)=0.008;SE=0.004;p=0.023).Longitudina. investiga.ions demonstra.ed tha. higher concentra.ions of IF1 a. the 1-yea. visit predicted a.fa.ter decline in Pa.levels over the subsequent 2 yea.s(time×IF1:B=0.148;SE=0.066;p=0.025).Conclusion:This study demonstra.es tha. regula. Pa.is a.socia.ed with pla.ma.IF1 concentra.ions,a.d it suggests tha. a.oa.I pa.tly med

关键词： a.ing a.olipoprotein Bioenergetics Exerkine Mitochondria

Histopa.hologica. impa.t of Sa.S-CoV-2 on the liver:Cellula. da.a.e a.d long-term complica.ions

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World Journa. of Ga.troenterology 2024年第22期30卷 2866-2880页

作者： a.fonso Rodriguez-Espa.a.Moises Sa.ga.o-de la.Mora.Bria.a.Ma.iette Rodriguez-Pa.ia.ua.Na.ha.y Limonde la.Rosa.Monica.Itzel martinez-Gutierrez Sa.tia.o Pa.tra.a.Bra.des Na.u Na.a.ro-a.va.ez Depa.tment of Molecula. Biology Universidad Panamericana School of MedicineCampus MéxicoMexico 03920Mexico Depa.tment of Interna. Medicine Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico 14080Mexico Depa.tment of Surgery University of Colorado Anschutz Medical CampusDenverCO 80045United States PECEM Facultad de MedicinaUniversidad Nacional Autónoma de MéxicoMexico 04360Mexico Depa.tment of Ga.troenterology Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico 14080Mexico

Corona.irus disea.e 2019(COVID-19),ca.sed by the highly pa.hogenic severe a.ute respira.ory syndrome corona.irus 2(Sa.S-CoV-2),prima.ily impa.ts the respira.ory tra.t a.d ca. lea. to severe outcomes such a. a.ute respira.ory distress syndrome,multiple orga. fa.lure,a.d *** extensive studies on the pa.hogenicity of Sa.S-CoV-2,its impa.t on the hepa.obilia.y system rema.ns *** liver injury is commonly indica.ed by reduced a.bumin a.d eleva.ed bilirubin a.d tra.sa.ina.e levels,the exa.t source of this da.a.e is not fully *** mecha.isms for injury include direct cytotoxicity,colla.era. da.a.e from infla.ma.ion,drug-induced liver injury,a.d ischemia.***,evidence often relies on blood tests with liver enzyme *** this comprehensive review,we focused solely on the different histopa.hologica. ma.ifesta.ions of liver injury in COVID-19 pa.ients,dra.ing from liver biopsies,complete a.topsies,a.d in vitro liver *** present evidence of the direct impa.t of Sa.S-CoV-2 on the liver,substa.tia.ed by in vitro observa.ions of vira. entry mecha.isms a.d the a.tua. presence of vira. pa.ticles in liver sa.ples resulting in a.va.iety of cellula. cha.ges,including mitochondria. swelling,endopla.mic reticulum dila.a.ion,a.d hepa.ocyte *** ly,we describe the diverse liver pa.hology observed during COVID-19 infection,encompa.sing necrosis,stea.osis,cholesta.is,a.d lobula. *** a.so discuss the emergence of long-term complica.ions,nota.ly COVID-19-rela.ed seconda.y sclerosing *** the histopa.hologica. liver cha.ges occurring during COVID-19 infection is pivota. for improving pa.ient recovery a.d guiding decision-ma.ing.

关键词： Liver Sa.S-CoV-2 COVID-19 a.giotensin-converting enzyme 2 Histopa.hology Liver biopsies Liver a.topsy In vitro

Supplementa.ion of vita.in E or a.bota.ica. extra.t a. a.tioxida.ts to improve growth performa.ce a.d hea.th of growing pigs housed under thermoneutra. or hea.-stressed conditions

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Journa. of a.ima. Science a.d Biotechnology 2024年第3期15卷 1101-1118页

作者： Ysenia.V.Silva.Guillen Consuelo a.ella.o Jeffrey Wiegert R.Dea. Boyd Ga.riela.E.martinez Eric va. Heugten Depa.tment of a.ima. Science North Carolina State UniversityRaleighNC 27695USA Depa.tment of Sta.istics North Carolina State UniversityRaleighNC 27695USA Depa.tment of a.ima. Science Texas A&M UniversityCollege StationTX 77843USA a.ima. Nutrition Resea.ch LLCAlvatonKY 42122USA.

Ba.kground Hea. stress ha. severe nega.ive consequences on performa.ce a.d hea.th of pigs,lea.ing to significa.t economic *** objective of this study wa. to investiga.e the effects of supplementa. vita.in E a.d a.bota.ica. extra.t in feed or drinking wa.er on growth performa.ce,intestina. hea.th,a.d oxida.ive a.d immune sta.us in grow-ing pigs housed under hea. stress *** Duplica.e experiments were conducted,ea.h using 64 crossbred pigs with a. initia. body weight of 50.7±3.8 a.d 43.9±3.6 kg a.d a.e of 13-week a.d 12-week,***(n=128)were housed individua.ly a.d a.signed within weight blocks a.d sex to a.2×4 fa.toria. a.ra.gement consisting of 2 environments(thermo-neutra.(21.2℃)or hea.-stressed(30.9℃))a.d 4 supplementa.ion trea.ments(control diet;control+100 IU/L of D-α-tocopherol in wa.er;control+200 IU/kg of DL-α-tocopheryl-a.eta.e in feed;or control+400 mg/kg of a.bota.ica. extra.t in feed).Results Hea. stress for 28 d reduced(P≤0.001)fina. body weight,a.era.e da.ly ga.n,a.d a.era.e da.ly feed inta.e(-7.4 kg,-26.7%,a.d-25.4%,respectively)but no effects of supplementa.ion were detected(P>0.05).Serum vita.in E increa.ed(Pa.in E supplementa.ion in wa.er a.d in feed(1.64 vs.3.59 a.d 1.64 vs.3.24),but not for the bota.ica. extra.t(1.64 vs.1.67 mg/kg)a.d wa. grea.er when supplemented in wa.er ***(P=0.002).Liver vita.in E increa.ed(Pa.in E supplementa.ions in wa.er(3.9 vs.31.8)a.d feed(3.9 vs.18.0),but not with the bota.ica. extra.t(3.9 vs.4.9 mg/kg).Serum ma.ondia.dehyde wa. reduced with hea. stress on d 2,but increa.ed on d 28(intera.tion,Pa.d wa. grea.er(Pa.tioxida.t supplementa.ion compa.ed to *** prolifera.ion wa. reduced(P=0.037)in the jejunum under hea. stress,but increa.ed in the ileum when vita.in E wa. supplemented in feed a.d wa.er under hea. stress(intera.tion,P=0.04).Tumor necrosis fa.tor-αin jejunum a.d ileum mucosa.decrea.ed by hea. stress(Pa.d wa. re

关键词： Bota.ica. extra.t Growing pigs Hea. stress Immune sta.us Oxida.ive sta.us Tocopherol Wa.er