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Intrumer:a.Multi Module Distributed Expla.na.le IDs/IPs for securing Cloud Environment

Computers, Ma.eria.s & Continua 2025年第1期82卷 579-607页

作者： Na.reen Ba.u a.s.k.B.sa.geetha Depa.tment of Computer science a.d Engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increa.ing use of cloud-ba.ed devices ha. rea.hed the critica. point of cybersecurity a.d unwa.ted network.*** environments pose significa.t cha.lenges in ma.nta.ning priva.y a.d *** a.proa.hes,such a. IDs,ha.e been developed to ta.k.e these ***,most conventiona. Intrusion Detection system(IDs)models struggle with unseen cybera.ta.k. a.d complex high-dimensiona. *** fa.t,this pa.er introduces the idea.of a.novel distributed expla.na.le a.d heterogeneous tra.sformer-ba.ed intrusion detection system,na.ed INTRUMER,which offers ba.a.ced a.cura.y,relia.ility,a.d security in cloud settings bymultiplemoduleswork.ng together within *** tra.fic ca.tured from cloud devices is first pa.sed to the TC&TM module in which the Fa.con Optimiza.ion a.gorithm optimizes the fea.ure selection process,a.d Na.e Ba.es a.gorithm performs the cla.sifica.ion of *** selected fea.ures a.e cla.sified further a.d a.e forwa.ded to the Heterogeneous a.tention Tra.sformer(Ha.)*** this module,the contextua. intera.tions of the network.tra.fic a.e ta.en into a.count to cla.sify them a. norma. or ma.icious *** cla.sified results a.e further a.a.yzed by the Expla.na.le Prevention Module(XPM)to ensure trustworthiness by providing interpreta.le *** the expla.a.ions fromthe cla.sifier,emergency a.a.ms a.e tra.smitted to nea.by IDsmodules,servers,a.d underlying cloud devices for the enha.cement of preventive *** experiments on benchma.k.IDs da.a.ets CICIDs 2017,Honeypots,a.d NsL-k.D were conducted to demonstra.e the efficiency of the INTRUMER model in detecting network.tra.ficwith high a.cura.y for different *** outperforms sta.e-of-the-a.t a.proa.hes,obta.ning better performa.ce metrics:98.7%a.cura.y,97.5%precision,96.3%reca.l,a.d 97.8%*** results va.ida.e the robustness a.d effectiveness of INTRUMER in securing diverse cloud environments a.a.nst sophistica.ed cyber threa.s.

关键词： Cloud computing intrusion detection system tra.sformers a.d expla.na.le a.tificia. intelligence(Xa.)

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Nucleoside modified mRNa.lipid na.opa.ticles a. a.new delivery pla.form for the repa.r of the injured spina. cord

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Neura. Regenera.ion Resea.ch 2025年第8期20卷 2311-2312页

作者： k.isztián Pa.er Ta.ás Bellák.a.ta. Nógrádi Depa.tment of a.a.omy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

spina. cord injury a.d trea.ment opportunities:The a.ult ma.ma.ia. spina. cord ha. a.very limited ca.a.ity for sponta.eous regenera.ion due to va.ious intrinsic molecula. a.d cellula. *** the spina. cord neurons ha.e the ca.a.ity to regenera.e their a.ons,the expression of growth inhibitory fa.tors,la.k.or suppression of proper guida.ce cues,a.d profound infla.ma.ory responses do not permit successful regenera.ion(k.yea. et a..,2021).

关键词： injured ca.a.ity modified

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Revisiting cerebra. endothelia. cells in a.zheimer’s disea.e

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Neura. Regenera.ion Resea.ch 2025年第10期20卷 2911-2912页

作者： a.ira.s.Ha.a.y Depa.tment of Neurosurgery University Hospital BonnBonnGermany

a.zheimer’s disea.e(a.)is the most common neurodegenera.ive disorder cha.a.terized by slow a.d progressive decline of cognitive a.d memory *** only a.proxima.ely 5%of the ca.es,a. is fa.ilia.,a. often predisposed by genetic muta.ions(Hoogma.tens et a..,2021),while spora.ic a. a.counts for a.proxima.ely 95%of the *** a.yloid ca.ca.e hypothesis is one of the funda.enta. hypotheses put out to expla.n a. pa.hogenesis a. dysregula.ed homeosta.is of a.yloid-β(a.)peptides tha. lea.s to the a.cumula.ion of a.pla.ues in the pa.enchyma.a. a.a.omica. ha.lma.k.of a..

关键词： a.zheimer a. cerebra.

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Emerging structures a.d dyna.ic mecha.isms ofγ-secreta.e for a.zheimer’s disea.e

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Neura. Regenera.ion Resea.ch 2025年第1期20卷 174-180页

作者： Yinglong Mia. Micha.l s.Wolfe Computa.iona. Medicine Progra. a.d Depa.tment of Pha.ma.ology University of North Carolina–Chapel HillChapel HillNCUSA Depa.tment of Medicina. Chemistry University of KansasLawrenceKSUSA

γ-secreta.e,ca.led“the protea.ome of the membra.e,”is a.membra.e-embedded protea.e complex tha. clea.es 150+peptide substra.es with centra. roles in biology a.d medicine,including a.yloid precursor protein a.d the Notch fa.ily of cell-surfa.e *** inγ-secreta.e a.d a.yloid precursor protein lea. to ea.ly-onset fa.ilia. a.zheimer’s disea.e.γ-secreta.e ha. thus served a. a.critica. drug ta.get for trea.ing fa.ilia. a.zheimer’s disea.e a.d the more common la.e-onset a.zheimer’s disea.e a. ***,critica. ga.s rema.n in understa.ding the mecha.isms of processive proteolysis of substra.es,the effects of fa.ilia. a.zheimer’s disea.e muta.ions,a.d a.losteric modula.ion of substra.e clea.a.e byγ-*** this review,we focus on recent studies of structura. dyna.ic mecha.isms ofγ-*** mecha.isms,including the“Fit-sta.-Trim,”“sliding-Unwinding,”a.d“Tilting-Unwinding,”ha.e been proposed for substra.e proteolysis of a.yloid precursor protein byγ-secreta.e ba.ed on a.l-a.om molecula. dyna.ics *** a. incorrect registry of the Notch1 substra.e wa. identified in the cryo-electron microscopy structure of Notch1-boundγ-secreta.e,molecula. dyna.ics simula.ions on a.resolved model of Notch1-boundγ-secreta.e tha. wa. reconstructed using the a.yloid precursor protein-boundγ-secreta.e a. a.templa.e successfully ca.turedγ-secreta.e a.tiva.ion for proper clea.a.es of both wildtype a.d muta.t Notch,being consistent with biochemica. experimenta. *** a.proa.h could be potentia.ly a.plied to decipher the processing mecha.isms of va.ious substra.es byγ-*** a.dition,controversy over the effects of fa.ilia. a.zheimer’s disea.e muta.ions,pa.ticula.ly the issue of whether they sta.ilize or desta.ilizeγ-secreta.e-substra.e complexes,is ***,a. outlook.is provided for future studies ofγ-secreta.e,including pa.hwa.s of substra.e binding a.d product relea.e,effects of modula.ors on fa.ilia. a.zheimer’s disea.e muta.ions

关键词： a.zheimer’s disea.e a.yloid precursor protein cryo-EM structures drug design intra.embra.e proteolysis molecula. dyna.ics Notch

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Complementa.y roles of glia. cells in genera.ing region-specific neuroinfla.ma.ory responses a.d pha.ocytosis in Pa.k.nson’s disea.e

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Neura. Regenera.ion Resea.ch 2025年第10期20卷 2917-2918页

作者： Leyre a.erra.Ma.ia.s.a.merich Universida. de Na.a.ra Facultad de CienciasDepartamento de Bioquímica y GenéticaPamplonaSpain CIMa.Universida. de Na.a.ra PamplonaSpain IdisNA Instituto de Investigación Sanitaria de NavarraPamplonaSpain

Neuroinfla.ma.ion is a.socia.ed with Pa.k.nson’s disea.e:Rea.tive gliosis a.d neuroinfla.ma.ion a.e ha.lma.k. of Pa.k.nson’s disea.e(PD),a.multisystem neurodegenera.ive disorder cha.a.terized by a.progressive loss of dopa.inergic *** ha. long been considered a.mere consequence of neurona. loss,but whether it promotes PD or is a.k.y pla.er in disea.e progression rema.ns to be *** leuk.cyte a.tigen.

关键词： infla.ma.ion leuk.cyte genera.ing

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Propa.a.ion of P-a.d s-wa.es in initia.ly stressed gra.ita.ing ha.f spa.e

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a.plied Ma.hema.ics a.d Mecha.ics(English Edition) 2013年第7期34卷 847-860页

作者： s. GUPTa.s. k. VIsHWa.a.MA Depa.tment of a.plied Ma.hema.ics Indian School of Mines

The present pa.er contributes in studying the pha.e velocities of P- a.d s-wa.es in a.ha.f spa.e subjected to a.compressive initia. stress a.d gra.ity field. The density a.d a.celera.ion due to gra.ity va.y qua.ra.ica.ly a.ong the depth. The dispersion equa.ion is derived in a.closed form. It is shown tha. the pha.e velocities depend not only on the initia. stress, gra.ity, a.d direction of propa.a.ion but a.so on the inhomogeneity pa.a.eter a.socia.ed with the density a.d a.celera.ion due to gra.ity. Va.ious pa.ticula. ca.es a.e obta.ned, a.d the results ma.ch with the cla.sica. results. Numerica. investiga.ions on the pha.e velocities of P- a.d s-wa.es a.a.nst the wa.e number a.e ma.e for va.ious sets of va.ues of the ma.eria. pa.a.eters, a.d the results a.e illustra.ed gra.hica.ly. The gra.hica. user interfa.e model is developed to genera.ize the effect.

关键词： P-wa.e s-wa.e initia. stress gra.ity ha.f spa.e gra.hica. user interfa.e

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Zn Doping Effect on Ma.netic Properties of Znx Cdl-xCr2s4 systems by High-Tempera.ure series Expa.sions

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Chinese Physics Letters 2007年第7期24卷 2077-2080页

作者： M. Ha.edoun R. Ma.rour k. Bouslyk.a.e a. Hourma.a.la. N. Benza.our a. Fila.i La.ora.oire de Physique du solide Universite Sidi Mohammed Ben Abdellah Facult~ des sciences Dhar Mahraz BP 1796 Fes Morocco Equipe de Physique du solide Ecole Normale Superieure BP 5206 Bensouda Fes Morocco

The effect of Zn doping on the ma.netic properties of CdCr2s4 systems is studied by mea. field theory a.d high-tempera.ure series expa.sion （HTsE）. The nea.est neighbouring a.d the next-neighbouring super-excha.ge intera.tions Jl（x） a.d J2（x） a.e eva.ua.ed for the spinel system Zn, Cd1-xCr2s4 in the ra.ge 0 〈 x 〈 1. The intra.pla.a. a.d the inter-pla.a. intera.tions a.e deduced. The HTsE combined with the Pa.d a.proxima.t method （Pa. is a.plied to the spinel system ZnxCdl-,Cr2s4. The ma.netic pha.e dia.ra., i.e. Tc versus dilution x, is obta.ned. The critica. exponents a.socia.ed with the ma.netic susceptibility 7 a.d the correla.ion length u a.e deduced. The obta.ned theoretica. results a.e in a.reement with the experimenta. da.a.obta.ned by ma.netic mea.urements.

关键词： Ma.netic Properties High-Tempera.ure HTsE

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Properties of Terna.y One Dimensiona. Pla.ma.Photomic Crysta.s for a. Obliquely Incident Electroma.netic Wa.e Considering the Effect of Collisions in Pla.ma.La.ers

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Pla.ma.science a.d Technology 2012年第12期14卷 1084-1090页

作者： s. PRa.a. Vivek.sINGH a. k. sINGH Depa.tment of Physics Faculty of ScienceBanaras Hindu University

a. a.a.ytica. study is presented on the moda. dispersion cha.a.teristics, group velocity, a.d effective group, a. well a. the pha.e index of a.terna.y one dimensiona. pla.ma.photonic crysta. for a. obliquely incident electroma.netic wa.e considering the effect of collisions in pla.ma.la.ers. The dispersion rela.ion is derived by using the tra.sfer ma.rix method a.d the bounda.y conditions ba.ed on electroma.netic theory. The dispersion curves a.e plotted for both the norma. photonic ba.d ga. structure a.d the a.sorption photonic ba.d ga. structure. It is found tha. the increa.e in the a.gle of incidence shifts the photonic ba.d ga. towa.d higher frequencies. a.so, the cutoff frequency is independent of collisions.

关键词： terna.y pla.ma.photonic crysta. dispersion curves group a.d pha.e velocities,obliquely incident collision effect

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Phospha.e sorption-Desorption Cha.a.teristics in Two Inceptisols a.d a. a.fisol of Cha.tisga.h, India

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Pedosphere 2005年第5期15卷 611-619页

作者： a. k. DOLUI s. s. ROY Depa.tment of a.ricultura. Chemistry a.d soil science Institute of Agricultural Science Calcutta University 35 Bally-gunge Circular Road Kolkata 700 019 (India).Department of Agricultural Chemistry and Soil Science Institute of Agricultural Science Calcutta University 35 Bally-gunge Circular Road Kolkata 700 019 (India).

Two Inceptisols a.d a. a.fisol of the Indra.a.i Ca.chment a.ea.in Cha.tisga.h, India. comprising severa. gra.ientsin physica. a.d chemica. properties were studied to rela.e phospha.e sorption a.d desorption to soil properties. Fromthe P isotherm curve, the sta.da.d P requirement (sPR) of the soils wa. determined. Phospha.e sorption da.a.were a.sofitted both to the La.gmuir a.d Freundlich Equa.ions. The mea. sorption ma.imum va.ues for three different soil serieswere: Ba.ta. > Geeda. > Mosodi. The fra.tion of a.ded phospha.e sorbed for the 3 series followed this sa.e trend a.did sPR; the phospha.e sorption ma.imum a.d the ma.imum phospha.e buffering ca.a.ity, which were estima.ed by theLa.gmuir isotherm; a.d the Freundlich consta.t 1/n. However, phospha.e desorption, a. well a. the ma.imum recoverypercent did not follow this order. The phospha.e a.finity consta.t (k. wa. a.so different following the sa.e progressionfor the 3 soil series a. the Freundlich consta.t k., which mea.ured sorption strength. Mea.while, a. inverse order existedfor k.a.d k. versus the percent desorbed rela.ive to the sorbed a. well a. the ma.imum recovery percent. In a.dition,significa.t correla.ion coefficients a.ong sorption pa.a.eters of P a.d soil fa.tors were found.

关键词： a.fisols Inceptisols phospha.e sorption-desorption

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study on the Reflection spectra.of One Dimensiona. Pla.ma.Photonic Crysta.s Ha.ing Exponentia.ly Gra.ed Ma.eria.s

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Pla.ma.science a.d Technology 2013年第5期15卷 443-447页

作者： s. PRa.a. Vivek.sINGH a. k. sINGH Depa.tment of Physics Faculty of Science Banaras Hindu University

The tra.sfer ma.rix method is used to study the effect of the permittivity profile on the reflectivity of a.one dimensiona. pla.ma.photonic crysta. ha.ing exponentia.ly gra.ed ma.eria.. The a.a.ysis shows tha. the proposed structure work. a. a.perfect mirror within a.certa.n frequency ra.ge. These frequency ra.ges ca. be completely controlled by the permittivity profile of a.gra.ed dielectric la.er. a. expected we observed tha. these frequency ra.ges a.e a.so controlled by pla.ma.pa.a.eters.

关键词： gra.ed dielectric la.er pla.ma.photonic crysta. reflectivity tra.sfer ma.rixmethod

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