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Study of Vita.in D Receptor (VDR) Gene Polym.rphism. a.ong Egyptia. Cohort Pa.ients with Different Sta.es of Colorecta. Ca.cer

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Journa. of Ca.cer Thera.y 2014年第3期5卷 253-263页

作者： m.ha.ed m. Rizk.Nerm.ne H. zakaria Wa.eed G. Elsha.ely Clinica. Pa.hology Depa.tm.nt Faculty of Medicine Alexandria University Alexandria Egypt Colorecta. Surgery Depa.tm.nt Faculty of Medicine Alexandria University Alexandria Egypt

Colorecta. ca.cer represents the third ca.cer worldwide. Studies showed tha.insufficient levels of vita.in D m.0} result in colorecta. ca.cer. Genetic va.ia.ions in genes controlling vita.in D a.tivity would pla. a.role in determ.ning susceptibility to colorecta. ca.cer. a.m.of the work. to study the different genotypes of VDR polym.rphism. a.d detect the a.socia.ion between serum.levels of 25(OH)VitD a.d 1,25(OH)2VitD a.ong sa.ple of Egyptia. pa.ients with different sta.es of colorecta. ca.cer. m.thods: Ninety pa.ients (60 with different sta.es of colorecta. ca.cer a.d 30 pa.ients with benign pa.hology of the colon) together with 30 hea.thy controls were exa.ined using PCR-RFLP a.a.ysis for Fok., a.a. a.d Ta.I polym.rphism.. Results: Genotype distribution for a.a. polym.rphism.showed no sta.istica.ly significa.t difference between pa.ients (colorecta. ca.cer a.d benign) a.d controls with p = 0.1. There wa. no sta.istica.ly significa.t difference in Fok. polym.rphism.where p = 0.26 a.d genotype distribution for Ta.I wa. a.so insignifica.t with p = 0.016. The m.dia. serum.level of 25(OH)VitD wa. low in ca.cer ca.es com.a.ed to the control group a.d benign ca.es with (p 0.001). There wa. no sta.istica.lysignifica.t difference of m.dia. serum.level of 1,25(OH)2VitD between benign a.d ca.cer ca.es. There wa. sta.istica.ly significa.t difference of m.dia. serum.level of 25(OH)VitD a.d 1,25(OH)2VitD between sta.e I a.d sta.e II with (p = 0.004) a.d (p 0.001), a.d between sta.e I a.d sta.e III with (p = 0.001)a.d (p 0.001), but no sta.istica.ly significa.t difference between sta.e II a.d III with (p = 0.514). Conclusions: There is ethnic va.ia.ility in vita.in D receptor gene polym.rphism.. The la.k.of significa.t a.socia.ion of the studied gene polym.rphism.in our popula.ion suggests tha. its a.socia.ion with other functiona.ly k.own gene polym.rphism.m.ght ha.e a.role in the pa.hogenesis of colorecta. ca.cer.

关键词： Vita.in D Receptor (VDR) Colorecta. Ca.cer (CRC) PCR-RFLP (Polym.rphism.

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Critica. physicochem.ca. a.tributes of chitosa. na.opa.ticles a.m.xed la.tose-PEG 3000 m.cropa.ticles in pulm.na.y inha.a.ion

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a.ia. Journa. of Pha.m.0}eutica. Sciences 2020年第3期15卷 374-384页

作者： Na.ser a.ha.j Za.liza.zakaria Ida.a.a.i Na.a.udin Fa.hrul a.sa. Wenji Li Tin Wui Wong Non-Destructive Biom.dica. a.d Pha.m.0}eutica. Resea.ch Centre iPROMISEUniversiti Teknologi MARAPuncak Alam 42300Malaysia Pa.ticle Design Resea.ch Group Faculty of PharmacyUniversiti Teknologi MARAPuncak Alam 42300Malaysia Depa.tm.nt of Pha.m.0}eutica. Sciences School of PharmacyTexas Tech University Health Sciences CenterAmarillo 79106USA Depa.tm.nt of Integra.ed Tra.itiona. Chinese a.d Western m.dicine Medical CollegeYangzhou UniversityYangzhou 225001China

Chitosa. na.opa.ticles a.e exha.a.ion prone a.d a.glom.ra.ive to pulm.na.y *** na.opa.ticles with la.tose m.cropa.ticles(~5 μm. could m.tua.ly reduce their a.glom.ra.ion through surfa.e a.sorption phenom.non. The chitosa. na.opa.ticles of va.ying size, size distribution, zeta.potentia., crysta.linity, sha.e a.d surfa.e roughness were prepa.ed by spra. drying technique a. a.function of chitosa., surfa.ta.t a.d processing conditions. La.tose-polyethylene glycol 3000(PEG3000) m.cropa.ticles were sim.la.ly prepa.ed. The chitosa. na.opa.ticles, physica.ly blended with fine la.tose-PEG3000 m.cropa.ticles, exhibited a.com.a.a.le inha.a.ion perform.0}ce with the com.ercia. dry powder inha.er products(fine pa.ticle fra.tion between 20% a.d 30%). Ca.ca.e im.a.tor a.a.ysis indica.ed tha. the a.rosoliza.ion a.d inha.a.ion perform.0}ce of chitosa. na.opa.ticles wa. prom.ted by their higher zeta.potentia. a.d circula.ity, a.d la.ger size a.tributes of which led to reduced inter-na.opa.ticula.e a.grega.ion a.d fa.ored na.opa.ticles intera.ting with la.tose-PEG3000 m.cropa.icles tha. a.ded their delivery into deep a.d periphera. lungs.

关键词： Chitosa. Inha.a.ion Na.opa.ticle Pulm.na.y

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Strength Perform.0}ce a.d m.crostructure Cha.a.teristic of Na.ura.ly-Bonded Fiberboa.d Com.osite from.m.0}a.sia. Ba.boo(Ba.busa.vulga.is)

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Journa. of Renewa.le m.0}eria.s 2022年第10期10卷 2581-2591页

作者： Sha.ril a.ua. Ba.a.i m.hd Na.a.udin zakaria Sya.ful Osm.0} Fa.a. a.u m.ha.a. Ja.i Sa.d Reza.Hosseinpourpia Eco-Technology Progra. Faculty of Applied SciencesUniversiti Teknologi MARA(UiTM)Shah Alam40450Malaysia Engineering Resea.ch Centre Malaysian Agricultural Research and Development Institute(MARDI)Serdang43400Malaysia Depa.tm.nt of Forestry a.d Wood Technology Linnaeus UniversityVäxjö35195Sweden

This study investiga.ed the m.cha.ica. properties a.d m.crostructura. cha.a.teristics of fiberboa.d com.osite produced by na.ura.ly-bonded m.0}a.sia. ba.boo fiber(Ba.busa.vulga.is).The com.onents tha. obta.ned through soda.pulping of ba.boo culm. such a. fiber a.d bla.k.liquor,were used for the prepa.a.ion of high-density fibreboa.d com.osite a. two ta.get densities of 850 a.d 950 k./m.(3).The ba.boo fiberboa.d com.osite(BFC)were then produced a. 200°C a.d two pressing pa.a.eters of 125 a.d 175 s/*** m.cha.ica. properties,e.g.,flexura. strength a.d interna. bonding(IB)of BFC sa.ples were eva.ua.ed a.cording to BS EN 310:1993 a.d BS EN 319:1993,*** wa. found tha. the m.cha.ica. perform.0}ce of the com.osite with 850 k./m.(3)density wa. significa.tly higher tha. 950 k./m.(3)ones,especia.ly for the sa.ples with 125 s/m. pressing *** cha.a.teristic of the BFC sa.ples illustra.ed tha. the fiber link.0}es were cra.k.d in the com.osites with higher density,e.g.,the com.osite with the density of 950 k./m.(3)a.d a.so bla.k.liquor were slightly degra.ed a. longer pressing tim.,which led to the reduction in m.cha.ica. properties,especia.ly in IB strength.

关键词： Ba.boo fiber na.ura.ly-bonded bla.k.liquor m.cha.ica. properties SEm com.osite

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Evidence of Fungicides Degra.a.ion by Rhizobia

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a.ricultura. Sciences 2014年第7期5卷 618-624页

作者： Ha.sa. m.a.a. Wa.a. m. a.d El-Ra.im.Ha.tha. Sha.k. a.iz m. Higa.y zakaria Y. Da. Colla.e of a.plica.ions Science MISR University for Science and Technology 6th of October City Egypt Depa.tm.nt of a.ricultura. m.crobiology a. fa.ulty of a.riculture Cairo University Cairo Egypt Depa.tm.nt of a.ricultura. m.crobiology a. Na.iona. Resea.ch Center Cairo Egypt

Fungicides which a.e not ea.ily degra.a.le ha.e the grea.est a.verse effects on soil m.crobes. These pesticides nega.ively a.fect the growth a.d m.ltiplica.ion of fungi a.d ba.teria.a.d consequently ca.se the disturba.ce of the na.ura. soil m.crobia. ba.a.ce. In this study two fungicide tolera.t isola.es of rhizobia.clover isola.e (Ta.) a.d pea.ut isola.e (8) were a.sessed in their ca.a.ity to degra.e Vita.a. a.d Rizolex. The perform.0}ce of these isola.es in fungicides degra.a.ion wa. tested using the colorim.tric a.sa. for Rizolex a.d the HPLC a.a.ysis for Vita.a. to detect the degra.a.ion products. Using HPLC a.a.yses, the control sa.ple showed specific pea. indica.ing the Vita.a. presence in the m.dium. The specific pea. did not cha.ge in the control sa.ples throughout the *** the stra.nTa. the specific pea. of the Vita.a. fungicides sta.ted to reduce a. the incuba.ion tim. goes on. The Vita.a. fungicide did not degra.e com.letely a.ter 240 hours of incuba.ion with rhizobia. isola.e. The Rizolex used in this study conta.ned blend of Thira. (a.tive ingredient of Rizolex) a.d Tolcofs m.thyl fungicides in 1:1 ra.io. The biodegra.a.ion of Rizolex in the liquid m.dia.showed the form.0}ion of two new interm.dia.es which were relea.ed into the m.dium.indica.ing the degra.a.ion of the tested fungicide by pea.ut rhizobia. isola.e No. 8 in 48 hrs of incuba.ion 45% of this com.ound wa. degra.ed. This work.shows tha. the selection of fungicides tolera.t rhizobia. stra.ns is im.orta.t to protect the rhizobia. inocula.ts from.the toxic effect of the pesticides.

关键词： Fungicides Rhizobia Biodegra.a.ion HPLC a.a.yses

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Towa.ds a. ea.ier pleurodesis: Ultra.ound-guided iodopovidone sclerothera.y in cirrhotic pa.ients with hepa.ic hydrothora.

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Open Journa. of Ga.troenterology 2013年第3期3卷 196-201页

作者： a.m.d m. a.delha.eez m.ha.m.d W. zakaria Wa.eed F. Fa.ha.a. Da.ia.Om.a. Chest Depa.tm.nt Faculty of Medicine Cairo University Cairo Egypt Endem.c m.dicine a.d Hepa.ology Depa.tm.nt Faculty of Medicine Cairo University Cairo Egypt

Ba.k.round a.d a.m. Hepa.ic hydrothora. is one of the com.lica.ions encountered in end sta.e liver disea.e. Pleura. dra.na.e ca.ries the risk.of m.0}sive protein a.d electrolyte depletion a. well a. the risk.of bleeding a.d hepa.ic encepha.opa.hy. Pleurodesis following pleura. a.pira.ion decrea.es the cha.ce of pleura. effusion recurrence, a.d ha. been a.widely used long-sta.ding m.thod of controlling recurrent pleura. effusions. The a.m.of this study is to eva.ua.e the effect of pleurodesis using ultra.ound-guided iodopovidone sclerothera.y in hepa.ic hydrothora.. Pa.ients a.d m.thods: This prospective study included 56 pa.ients with clinica., la.ora.ory a.d ra.iologica. evidence of liver cirrhosis a.d sym.tom.0}ic right sided hepa.ic hydrothora.. a.l pa.ients were subjected to repea.ed thora.entesis. Ten m. of lidoca.ne 2% were injected in the pleura. spa.e followed by 20 m. of iodopovidone. The follow-up wa. done a.ter 3 m.nths. Results: The sclerothera.y procedure wa. successful in 40 out of 56 ca.es (71.4%), a.d the success ra.e wa. 66.7% in m.0}sive effusion a.d rea.hed 80% in m.dera.e effusion. Twenty eight pa.ients (50%) ha. to repea. the procedure for a.second tim., sixteen of which (28.6%) fa.led despite the second tria. a.d twelve ca.es (21.4%) showed no fluid rea.cum.la.ion. Conclusion: Ultra.ound-guided iodopovidone sclerothera.y is a. effective a.proa.h for a.successful pleurodesis in hepa.ic hydrothora..

关键词： Pleurodesis Ultra.ound Iodopovidone Effusion

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Rem.va. of Cesium.on Polya.iline Tita.otungsta.e a. Com.osite Ion Excha.ger

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a.va.ces in Chem.ca. Engineering a.d Science 2012年第1期2卷 166-179页

作者： I.m. El-Na.ga. E. S. zakaria I. m. a.i m. k.a.il m. F. El-Sha.a. 不详

Polya.iline tita.otungsta.e (Pa.iW) wa. synthesized by the sol-gel m.thod. a.sorption isotherm.studies of Cs+ from.a.ueous solution a.e described. Elem.nta. Com.osition, chem.ca. solubility, ion-excha.ge ca.a.ity (IEC) a.d pH titra.ion a.e studied. Distribution coefficients (k.) for ten m.ta. ions ha.e been determ.ned. It wa. found tha. the polya.iline tita.otungsta.e ha. high a.finity a.d high selectivity for Cs+. The m.0}eria. wa. high sepa.a.ion of Cs+ from.other m.ta. ions. The a.sorbent ca.a.ity wa. determ.ned using the Freundlich a.d La.gm.ir a.sorption isotherm.m.dels. The Cs+ a.sorption isotherm.da.a.fit best to the Freundlich isotherm.m.del. The m.0}im.m.Cs+ upta.e of polya.iline tita.otungsta.e wa. found 217 m./g. a.colum. tests were perform.d to determ.ne the brea.through curves with va.ying bed depths a.d flow ra.es in different solutions. The results show tha. the ha.f brea.through tim. increa.es proportiona.ly with increa.ing bed depths. k.netic studies for rem.va. cesium.from.m.lk.were investiga.ed.

关键词： Synthesis Sepa.a.ion Polya.iline Tita.otungsta.e Cesium

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Intercontinenta. com.a.ison of lia.a.com.unity a.sem.la.es in tropica. forests of Gha.a.a.d m.0}a.sia

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Journa. of Pla.t Ecology 2017年第6期10卷 883-894页

作者： Pa.rick.a.do-Fordjour zakaria B.Ra.m.0} Robyn J.Burnha. School of Biologica. Sciences Universiti Sains Malaysia11800 Pulau Pinang PenangMalaysia Depa.tm.nt of Theoretica. a.d a.plied Biology College of ScienceKwame Nkrumah University of Science and Technology(KNUST)KumasiGhana Depa.tm.nt of Ecology a.d Evolutiona.y Biology University of MichiganAnn ArborMI 48109-1079USA

a.m. Lia.a.resea.ch ha. increa.ed in the pa.t two deca.es,yet there is still ina.equa.e com.a.ison of lia.a.com.unities a. a.cross-con-tinenta. *** com.a.ed lia.a.a.sem.la.es in tropica. forest ecosystem. of Gha.a.a.d m.0}a.sia.thereby determ.ning pa.terns a.d m.cha.ism. tha. a.e com.on or unique to the *** Lia.a.diversity,com.unity structure a.d ta.onom.c com.osition were determ.ned in 60 plots of 40×40 m. in three forest types(prim.0}y,disturbed seconda.y,selectively logged)in ea.h biogeo-gra.hic *** tra.ts,clim.ing m.cha.ism. a.d dispersa. m.des were determ.ned for a.l species a.d individua.s via.direct field observa.ion a.d with published *** were a.a.yzed a. biogeogra.hic(using com.ined forest da.a.a.d forest-type *** Findings Both observed a.d ra.efied-extra.ola.ed species richness of lia.a. were significa.tly higher in Gha.a.a. forests com.a.ed to m.0}a.sia. *** m.st ca.es,species diversity indices(Sha.non diversity index,m.0}ga.ef,Fisher’s a.pha.showed significa.tly higher lia.a.diversity a. Gha.a.a. forests a. biogeogra.hic a.d forest-type ***,Gha.a.a. forests ha.bored significa.tly higher va.ues of lia.a.a.unda.ce a.d ba.a. a.ea.tha. m.0}a.sia. forests a. both biogeogra.hic a.d forest-type *** ta.onom.c com.osition of lia.a. differed considera.ly between the two biogeogra.hic a.ea. a. a.l levels,a.though sim.la.ity in com.osition increa.ed a. generic a.d fa.ily *** a.ove-ground biom.0}s of lia.a. wa. sim.-la. between the two biogeogra.hic regions,va.ia.ions occurred a. forest-type level between the two *** two biogeogra.hic a.ea. showed som. sim.la.ities in a.sem.la.es of lia.a.clim.ing *** m.re species of lia.a. were a.a.ted for a.im.0} dispersa. tha. other dispersa. m.des in both countries,the m.0}ority of lia.a.individua.s in Gha.a.were wind dispersed wherea. the m.0}ority of lia.a.individua.s in m.0}a.sia.were a.im.0} *** specula.e tha. the differ

关键词： biogeogra.hic region clim.ing m.cha.ism. dispersa. m.des intercontinenta. pa.terns lia.a.diversity lia.a.com.unity structure

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a.tica.cer a.tivity of a.oe vera.a.d Ca.ligonum.com.sum.extra.ts sepa.etely on hepa.ocellula. ca.cinom.0}cells

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a.ia. Pa.ific Journa. of Tropica. Biom.dicine 2015年第5期5卷 375-381页

作者： m.0}a. Sha.a.i k..k.ilo m.0}m.ud m.zakaria m.0}m.ud G.Elseba.i Wa.ied a.do Wa.a. a.a.in Depa.tm.nt of Biochem.stry Faculty of Veterinary Medicine Mansoura University Depa.tm.nt of Biochem.stry Faculty of Veterinary Medicine Kafrelsheikh University Urology a.d Nephrology Center Mansoura University Depa.tm.nt of Pa.hology Faculty of Veterinary Medicine Kafrelsheikh University Depa.tm.nt of Pa.hology Faculty of Veterinary Medicine Mansoura University

Objective: To investiga.e the in vitro a.tica.cer effect of a.oe vera.a. vera. a.d Ca.ligonum.com.sum.C. com.sum. extra.ts a.a.nst hepa.ocellula. ca.cinom.0}HepG 2) cells. m.thods: Hep G2 cells were tested a.a.nst different doses of a. vera.a.d C. com.sum. Via.ility of the cells wa. a.sessed by m.T a.sa.. Eva.ua.ion of a.optosis a.d DNa.da.a.e in HepG 2 cells were perform.d using a.nexin V a.optosis detection k.t. The expression of p53 a.d a.ti-a.optotic(Bcl-2) were tested by rea. tim.-PCR a.d flow cytom.ter a.a.yser. Hem.0}oxylin a.d eosin sta.ned sections from.untrea.ed a.d trea.ed HepG 2 cells were observed using light ***: The IC50 va.ues of a. vera.a.d C. com.sum.extra.ts were(10.45 ± 0.31) a.d(9.60 ± 0.01) μg/m. respectively. The extra.ts sepa.a.ely increa.ed cytotoxicity a.a.nst HepG 2 cells in a.tim. a.d dose dependent m.0}ners. a.so, it a.pa.ently induced a.optosis through increa.e P53 a.d decrea.e Bcl-2 genes ***: The results indica.ed tha. the extra.ts could ha.e a.ti-hepa.oca.cinogenic effect, a. lea.t in pa.t, through m.dula.ion of a.optosis.

关键词： HepG2 Hepa.ocellula. ca.cinom. a.oe vera Ca.ligonum com.sum a.optosis

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Experim.nta. eva.ua.ion of a.hydrogra.hy surfa.e vehicle in four na.iga.ion m.des

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Journa. of Ocea. Engineering a.d Science 2017年第2期2卷 127-136页

作者： Hossein m.usa.a.eh Ja.a.biglu Ha.id Om.a.i Elha. m.nha.eri Fa.shid k.a.ei a.i Sa.m.0}i-zakaria Yousef m.0}hsoos a.hk.0} m.cha.ica. Engineering of Biosystem. University of TehranIran m.cha.ica. Engineering of Biosystem. University of Shahrekord and Expert of Ports and Maritime OrganizationIran

Considering the effectiveness of m.0}itim. tra.sporta.ion,a.la.ge num.er of world’s tra.e is ca.ried by sea.a.d *** ports a.d ha.bors a.e essentia. for 24 hourly loa.ing/unloa.ing of *** this rega.d,ba.hym.try a.d m.nitoring of depth da.a.especia.ly in rea. tim. m.0}ner would be very va.ua.le a.d *** plot hydrogra.hy m.0} of ports a.d ha.bors in the burea. a. online a.d with low cost,a.Surfa.e Vehicle(SV)is designed a.d *** vehicle could na.iga.e in four *** could sea. on the boa. a.d run by joystick.or sta.d in slipwa. a.d control by Rem.te Controller(RC)or sea. in the office a.d na.iga.e by a.user friend gra.hica. *** the boa. could na.iga.e fully a.tonom.us without a.y *** a.cura.y a.d precision of four m.ntioned na.iga.ion m.des wa. the m.0}n objective of this *** results illustra.ed tha. a.tonom.us m.de with Sta.da.d Devia.ion(SD)of below 0.5 m.wa. the m.st precision a.d com.orta.le m.de,while RC is the m.re relia.le a.d trustworthy.

关键词： a.tonom.us,Na.iga.ion Hydrogra.hy Surfa.e vehicle m.nitoring

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Cha.a.teriza.ion of m.cha.ica. a.d Corrosion Properties of Cryorolled a.um.nium.1100 a.loy: Effect of a.nea.ing a.d Solution Trea.m.nt

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Tra.sa.tions of Nonferrous m.ta.s Society of China 2021年

作者： S.a.zakaria a.S.a.a.yida.H.Zuha.la.a.i B.k.Dhinda. N.a.Ja.it a.Ism.0}l Structura.m.0}eria.sNichea.ea.Schoolofm.0}eria.s&m.nera.ResourcesEngineering，UniversitiSa.nsm.0}a.sia India.InstituteofTechnologyk.a.a.pur721302 Depa.tm.ntofm.0}eria.sEngineeringa.dDesignFa.ultyofm.cha.ica.a.dm.0}ufa.turingEngineering，UniversitiTunHusseinOnnm.0}a.sia.6400Ba.uPa.a.

Effect of a.nea.ing a.d solution trea.m.nt prior to cryorolling on the form.0}ion of initia. structure influencing m.crostructure form.0}ion from.na.o to m.cron sca.e a.d resulta.t m.cha.ica. a.d corrosion properties in a. 1100 a.loy ha. been studied in deta.l. Before subjecting to 50% cryorolling， sa.ples a.e pre-a.nea.ed a. 250℃ for 2 hours a.d pre-solution trea.ed a. 540℃ for 1 hour. X-ra. diffra.tion a.d HRTEm.techniques were used to understa.d the crysta.lite size， la.tice stra.n a.d disloca.ion configura.ion in the processed a.loy. The results indica.e tha. the pre-a.nea.ed sa.ple ha. the highest gra.n a.pect ra.io （4.43）， the sm.0}lest crysta.lite size （37.53 nm.， the highest la.tice stra.n (9.12×10-3) a.d the highest disloca.ion density (45.16 × 1013m.2) com.a.ed to the pre-solution trea.ed sa.ple. The pre-a.nea.ed sa.ple showed a.significa.t im.rovem.nt of 43.44%， 24.64%， a.d 20.33% in ha.dness， ultim.0}e tensile strength， a.d yield strength. Both pre-a.nea.ed a.d pre-solution trea.ed sa.ples showed im.roved corrosion resista.ce when com.a.ed to cryorolled sa.ples without a.y pre-trea.m.nt， with the pre-a.nea.ed sa.ple showing the best corrosion resista.ce.

关键词： Cryorolling a. 1100 a.loy pre-hea. trea.m.nt na.ostucture ultra.ine-gra.n m.cha.ica. properties corrosion resista.ce

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