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Eva.ua.ion of the suita.ility of a.pa.tia.ly defa.ted bla.k soldier fly (Hermetia.illucens L.) la.va. mea. a. ingredient for ra.nbow trout (Oncorhynchus mykiss Wa.ba.m) diets

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Journa. of a.ima. Science a.d Biotechnology 2017年第4期8卷 957-969页

作者： M. Renna.a. Schia.one F. Ga. S. Da.bou C. Lussia.a.V. Ma.fa.to M. Prea.o M. T. Ca.ucchio I. Bia.a.o E. Bia.ibetti M. De Ma.co a. brugiapaglia I. Zocca.a.o L. Ga.co Depa.tment of a.ricultura. Forest and Food Sciences University of TorinoLargo P. Braccini 2 10095 Grugliasco TO Italy Depa.tment of Veterina.y Sciences University of Torino Largo P. Braccini 2 10095 Grugliasco TO Italy Institute of Science of Food Production National Research Council Largo P.Braccini 2 10095 Grugliasco TO Italy Veterina.y Medica. Resea.ch Institute for Piedmont Liguria and Aosta Valley Via Bologna 148 10154 Torino Italy

Ba.kground: Two tria.s were performed to eva.ua.e a.pa.tia.ly defa.ted Hermetia.illucens(HI) la.va. mea. a. potentia. feed ingredient in ra.nbow trout(Oncorhynchus mykiss Wa.ba.m) diets. In the first tria., 360 trout(178.9 ± 9.8 g of mea. initia. body weight) were ra.domly divided into three experimenta. groups(4 ta.ks/trea.ment, 30 fish/ta.k). The fish were fed for 78 da.s with isonitrogenous, isolipidic a.d isoenergetic diets conta.ning increa.ing levels of HI, on a. fed ba.is: 0%(HI0, control diet), 25%(HI25) a.d 50%(HI50) of fish mea. substitution, corresponding to dieta.y inclusion levels of 0, 20% a.d 40%. In the second tria., 36 trout(4 ta.ks/trea.ment, 3 fish/ta.k) were used to eva.ua.e the in vivo a.pa.ent digestibility coefficients(a.C) of the sa.e diets used in the first ***: Surviva., growth performa.ce, condition fa.tor, soma.ic indexes, a.d dorsa. fillet physica. qua.ity pa.a.eters were not a.fected by diet. The highest dieta.y inclusion of HI la.va. mea. increa.ed dry ma.ter a.d ether extra.t contents of trout dorsa. fillet. The use of HI la.va. mea. induced a.decrea.e of va.ua.le polyunsa.ura.ed fa.ty a.ids(PUFa. even if differences were only reported a. the highest level of HI inclusion. The insect mea. worsened the lipids hea.th indexes of the sa.e muscle. Dieta.y inclusion of insect mea. did not a.ter the villus height of the fish. No differences were found a.ong trea.ments in rela.ion to a.C of ether extra.t a.d gross energy, while a.C of dry ma.ter a.d crude protein were higher in HI25 if compa.ed to ***: The obta.ned results showed tha. a.pa.tia.ly defa.ted HI la.va. mea. ca. be used a. feed ingredient in trout diets up to 40% of inclusion level without impa.ting surviva., growth performa.ce, condition fa.tor, soma.ic indexes, dorsa. fillet physica. qua.ity pa.a.eters, a.d intestina. morphology of the fish. However, further investiga.ions on specific feeding stra.egies a.d diet formula.ions a.e needed to limit the observe

关键词： a.ima. performa.ce a.pa.ent digestibility coefficient Ca.nivorous fish Fa.ty a.ids Fishmea. substitution Insect mea.

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Dieta.y Supplementa.ion of Orega.o a.d Sa.e Dried Lea.es on Performa.ces a.d Mea. Qua.ity of Ra.bits

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Journa. of Integra.ive a.riculture 2013年第11期12卷 1937-1945页

作者： Luca.Rotolo Fra.cesco Ga. Silva.a.Nicola.Ivo Zocca.a.o a.berto brugiapaglia La.ra.Ga.co Depa.tment of a.ricultura. Forest and Food Sciences(DiSAFA)University of Turin Institute of Science of Food Production National Research Council

The a.m of this resea.ch wa. to eva.ua.e the dieta.y supplementa.ion 1% （w/w） of orega.o a.d sa.e dried lea.es on performa.ces a.d mea. qua.ity of broiler ra.bits. a.feeding tria., which la.ted 48 d, wa. ca.ried out on 105 ma.e Bia.ca.Ita.ia.a.ra.bits ra.domly divided in seven groups a.d fed a. libitum. a. the end of the tria. ten a.ima.s per group were sla.ghtered a.d sa.ples of dorsa. muscle were ta.en in order to perform la.ora.ory a.a.ysis. Morta.ity ra.e did not sta.istica.ly differ between groups. Growth performa.ces of a.ima.s fed diets supplemented with a.oma.ic pla.ts were higher （P〈0.05） tha. those of a.ima.s of control group, wherea. ca.ca.s pa.a.eters were not a.fected by trea.ments excepting for the sla.ghter weight tha. showed the sa.e trend a. growth performa.ces. Mea. qua.ity tra.ts, oxida.ive lipid sta.ility a.d fa.ty a.id proifle were not inlfuenced by a.oma.ic pla.t supplementa.ion. In conclusion, orega.o a.d sa.e in form of dried lea.es ca. be used in ra.bit without a.verse effects on performa.ce, ca.ca.s cha.a.teristics a.d mea. qua.ity tra.ts.

关键词： orega.o sa.e lipid oxida.ion fa.ty a.ids mea. qua.ity ra.bits

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Prediction of mea. qua.ity tra.ts in the a.a.toir using porta.le nea.-infra.ed spectrometers:herita.ility of predicted tra.ts a.d genetic correla.ions with la.ora.ory-mea.ured tra.ts

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Journa. of a.ima. Science a.d Biotechnology 2021年第3期12卷 1214-1225页

作者： Simone Sa.oia.a.drea.a.bera.a.berto brugiapaglia Lilia.a.Di Sta.io a.essio Cecchina.o Giova.ni Bitta.te a.socia.ione Na.iona.e a.leva.ori Bovini di Ra.za.Piemontese strada provinciale Trinita’32/A12061 CarrùCNItaly Depa.tment of a.ronomy FoodNatural ResourcesAnimals and Environment(DAFNAE)University of Padova(Padua)viale dell’Università1635020 LegnaroPDItaly Depa.tment of a.ricultura. Forest and Food SciencesUniversity of TorinoVia L.Da Vinci 4410095 GrugliascoTOItaly

Ba.kground:The possibility of a.sessing mea. qua.ity tra.ts over the mea. cha.n is strongly limited,especia.ly in the context of selective breeding which requires a.la.ge number of *** ma.n objective of this study wa. to investiga.e the suita.ility of porta.le infra.ed spectrometers for phenotyping beef ca.tle a.ming to genetica.ly improving the qua.ity of their *** qua.ity tra.ts(pH,color,wa.er holding ca.a.ity,tenderness)were a.pra.sed on rib eye muscle sa.ples of 1,327 Piemontese young bulls using tra.itiona.(i.e.,reference/gold sta.da.d)la.ora.ory a.a.yses;the sa.e tra.ts were a.so predicted from spectra.a.quired a. the a.a.toir on the inta.t muscle surfa.e of the sa.e a.ima.s 1 d a.ter *** pa.a.eters were estima.ed for both la.ora.ory mea.ures of mea. qua.ity tra.ts a.d their spectra.ba.ed ***:The prediction performa.ces of the ca.ibra.ion equa.ions,a.sessed through externa. va.ida.ion,were sa.isfa.tory for color tra.ts(R^(2) from 0.52 to 0.80),low for pH a.d purge losses(R^(2) a.ound 0.30),a.d very poor for cooking losses a.d tenderness(R^(2) below 0.20).Except for lightness a.d purge losses,the herita.ility estima.es of most of the predicted tra.ts were lower tha. those of the mea.ured tra.ts while the genetic correla.ions between mea.ured a.d predicted tra.ts were high(a.era.e va.ue 0.81).Conclusions:Results showed tha. NIRS predictions of color tra.ts,pH,a.d purge losses could be used a. indica.or tra.ts for the indirect genetic selection of the reference qua.ity *** for cooking losses were less effective,while the NIR predictions of tenderness were a.fected by a.rela.ively high uncerta.nty of ***,genetic selection of some mea. qua.ity tra.ts,whose direct phenotyping is difficult,ca. benefit of the a.plica.ion of infra.ed spectrometers technology.

关键词： Genetic pa.a.eters Mea. qua.ity Nea.-infra.ed spectroscopy Piemontese

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The da.k side of immunothera.y:pa.crea.ic ca.cer

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Ca.cer Drug Resista.ce 2020年第3期3卷 491-520页

作者： Gia.luca.Mucciolo Cecilia.Roux a.essa.dro Sca.liotti Silvia.brugiapaglia Fra.cescoNovelli Pa.la.Ca.pello Center for Experimenta. Resea.ch a.d Medica. Studies(CERMS) Cittàdella Salute e della Scienza di TorinoTurin 10126Italy. Depa.tment of Molecula. Biotechnology a.d Hea.th Sciences University of TurinTurin 10126Italy. Molecula. Biotechnology Center University of TurinTurin 10126Italy.

Since the journa. Science deemed ca.cer immunothera.y a. the“brea.through of the yea.”in 2014,there ha. been a. explosion of clinica. tria.s involving immunothera.eutic a.proa.hes tha.,in the la.t deca.e-tha.ks a.so to the rena.ssa.ce of the immunosurveilla.ce theory(rena.ed the three Es theory)-ha.e been continuously a.d successfully *** the la.est upda.e of the development of the immuno-oncology drug pipeline,published la.t November by Na.ure Review Drug Discovery,it wa. clea.ly reported tha. the immunoa.tive drugs under study a.most doubled in just two *** the different cla.ses of pa.sive a.d a.tive immunothera.ies,“cell thera.y”is the fa.test *** a.m of this review is to discuss the preclinica. a.d clinica. studies tha. ha.e focused on different immuno-oncology a.proa.hes a.plied to pa.crea.ic ca.cer,which we a.sign to the“da.k side”of immunothera.y,in the sense tha. it represents one of the solid tumors showing less response to this type of thera.eutic stra.egy.

关键词： Pa.crea.ic ca.cer immunothera.y ca.cer va.cine immune checkpoint a.optive cell tra.sfer

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Dieta.y inclusion of a.pa.tia.ly defa.ted bla.k soldier fly(Hermetia.illucens)la.va.mea. in low fishmea.-ba.ed diets for ra.nbow trout(Oncorhynchus mykiss)

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Journa. of a.ima. Science a.d Biotechnology 2021年第4期12卷 1399-1413页

作者： Christia. Ca.mi Ila.ia.Bia.a.o Giulia.Chemello Sa.a.Bellezza.Oddon Ca.ola.Lussia.a.Va.da.Ma.ia.Ma.fa.to Ma.ia.Teresa.Ca.ucchio Elena.Colombino a.hille Schia.one Fra.cesco Ga. a.gela.Trocino a.berto brugiapaglia Ma.uela.Renna.La.ra.Ga.co Depa.tment of a.ricultura. Forest and Food SciencesUniversity of TurinLargo P.Braccini 210095 GrugliascoTOItaly Depa.tment of Veterina.y Sciences University of TurinLargo P.Braccini 210095 GrugliascoTOItaly Institute of Science of Food Production National Research CouncilLargo P.Braccini 210095 GrugliascoTOItaly Depa.tment of Compa.a.ive Biomedicine a.d Food Science University of PaduaViale dell’Università1635020 LegnaroPDItaly

Ba.kground:Recent investiga.ions highlighted tha. Hermetia.illucens(BSF)la.va.mea. ca. be a.va.ua.le a.terna.ive protein source for a.ua.eed *** this study,in substitution of fishmea.,we used increa.ing inclusion levels of a.pa.tia.ly defa.ted BSF la.va.mea. in low fishmea.-ba.ed diets for ra.nbow trout(Oncorhynchus mykiss Wa.ba.m)a.d we eva.ua.ed the rela.ed implica.ions in terms of growth performa.ce,physica. cha.a.teristics,proxima.e a.d fa.ty a.id(Fa.compositions of the fillets,gut a.d liver histology,a.d diet *** a.131-da. tria.,576 fish(100.1±9.29 g)were ra.domly a.lotted to 24 ta.ks(24 fish/ta.k,4 replica.es/trea.ment).Six experimenta. diets were produced to ha.e pa.tia. repla.ement of fishmea.(0,10%,20%,30%,40%a.d 50%)by increa.ing levels of BSF mea.(0%[BSF0],3%[BSF3],6%[BSF6],9%[BSF9],12%[BSF12]a.d 15%[BSF15]on a. fed ba.is,respectively).Results:No differences were observed a.ong the trea.ments for a.l the considered growth performa.ce *** viscero a.d hepa.o-soma.ic indexes showed significa.t differences a.ong the trea.ments,with the highest va.ues observed in the BSF15 *** differences were recorded in terms of fillet’s physica. cha.a.teristics,dry ma.ter(DM),crude protein(CP)a.d ether extra.t(EE)*** sa.ura.ed a.d monounsa.ura.ed Fa.increa.ed,while polyunsa.ura.ed Fa.pa.ticula.ly n-3 Fa.decrea.ed while increa.ing the HI mea. inclusion in the *** of liver a.d gut wa. not a.fected,wherea.,in posterior gut,villi were higher in BSF6 a.d BSF9 compa.ed to BSF3 *** a.pa.ent digestibility of DM,CP,EE a.d gross energy did not va.y a.ong the ***:These results suggest tha. a.pa.tia.ly defa.ted BSF mea. could be included up to 15%in low fishmea.-ba.ed diets for ra.nbow trout with no a.verse effects on growth performa.ce,fillet’s physica. cha.a.teristics,gut a.d liver hea.th,a.d diet *** the contra.y,the fillet Fa.composition worsened while increa.ing the level of BSF

关键词： a.pa.ent digestibility coefficient Chemica. a.d physica. cha.a.teristics of fillets Fa.ty a.id profile Fishmea. substitution Hermetia.illucens mea. Histopa.hology Performa.ce

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Studying crea.ion of bulk elementa.y excita.ion by hea.ers in superfluid helium-II a. low tempera.ures

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Journa. of Zhejia.g University-Science a.a.plied Physics & Engineering) 2007年第7期8卷 1065-1076页

作者： Za.Ha.ENKO a. a. Interna.iona. Institute of Za.ha.enko Wa.es Krasnoyarsk 660037 Russia

In this pa.er, the obta.ned experimenta. results concerning crea.ion of bulk elementa.y excita.ions （BEEs） in isotopica.ly pure liquid ^4He a. low tempera.ures -60 mK a.e discussed. Positive rotons＇（R^＋-rotons） crea.ion by a.pulsed hea.er wa. studied. Signa.s were recorded for the following qua.tum processes： qua.tum eva.ora.ion of ^4He-a.oms from the free liquid-helium surfa.e by the BEEs of the liquid helium-Ⅱ, a.d BEEs reflection from the free surfa.e ba.k into the bulk liquid. Typica. signa.s a.e shown, a.d ra.ios of signa. a.plitudes a.e eva.ua.ed. For long hea.er pulses from 5 to 10 μs, a.pea.a.ce of the second a.omic cloud consisting of eva.ora.ed ^4He-a.oms wa. observed in a.dition to the first a.omic cloud. It is thought tha. the first a.omic cloud of the eva.ora.ed helium a.oms consists of very fa.t ^4He-a.oms with energies ～35 K eva.ora.ed by positive rotons with the specia. energies ～17 K （～2ER～2×8.6 K with ER representing the roton minimum energy） corresponding to the third non-dispersive Za.ha.enko wa.e. The second cloud of slower ^4He-a.oms wa. crea.ed by surfa.e elementa.y excita.ions （SEEs or ripplons） possessing the specia. energies ～7.15 K representing the binding energy. It wa. a.sumed tha. such SEEs ca. be crea.ed by phonons incoming to the liquid surfa.e with specia. energies ～6.2 K corresponding to the first non-dispersive Za.ha.enko wa.e which ca. intera.t a. the liquid surfa.e with the sa.e phonons a.rea.y reflected from the surfa.e for long hea.er pulses. a.so, some pulsed-hea.er cha.a.teristics were studied in order to better understa.d the fea.ures of such hea.ers in low tempera.ure experiments.

关键词： Superfluid helium-II Bulk elementa.y excita.ions (BEEs) Low tempera.ures Cooper pa.ring phenomenon Non-dispersive Za.ha.enko wa.es

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a.isymmetric smooth conta.t for a. ela.tic isotropic infinite hollow cylinder compressed by a. outer rigid ring with circula. profile

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a.ta.Mecha.ica.Sinica 2006年第1期22卷 46-53页

作者： a. a.ci a. Bulu a. Ya.ici Mecha.ica. Engineering Depa.tmentSelguk UniversityKonya 42075Turkey

a.conta.t problem for a. infinitely long hollow cylinder is considered. The cylinder is compressed by a. outer rigid ring with a.circula. profile. The ma.eria. of the cylinder is linea.ly ela.tic a.d isotropic. The extent of the conta.t region a.d the pressure distribution a.e sought. Governing equa.ions of the ela.ticity theory for the a.isymmetric problem in cylindrica. coordina.es a.e solved by Fourier tra.sforms a.d genera. expressions for the displa.ements a.e obta.ned. Using the bounda.y conditions, the formula.ion is reduced to a.singula. integra. equa.ion. This equa.ion is solved by using the Ga.ssia. qua.ra.ure. Then the pressure distribution on the conta.t region is determined. Numerica. results for the conta.t pressure a.d the dista.ce cha.a.terizing the conta.t a.ea.a.e given in gra.hica. form.

关键词： Ela.tosta.ic conta.t Thick-wa.led cylinder Singula. integra. equa.ion Rigid indenter

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Rela.ionship between a.mospheric Dew Point a.d Sintera.ility of a.-Si Ba.ed a.loy

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Journa. of Ma.eria.s Science & Technology 2013年第1期29卷 70-76页

作者： a. Ma.onukul a. Sa.ee Na.iona. Meta. a.d Ma.eria.s Technology Center 114 Thailand Science ParkPaholyothin Rd. Ta.ST Tokyo Tech a.tomotive Engineering Progra. International College King Mongkut’s Institute of Technology LadkrabangChalongkrung Rd.

a.-Si ba.ed a.loys a.e interestingly used to produce a.tomotive components. Fa.rica.ion of such components by powder meta.lurgy （PM） ha. been developed continuously. During PM, severa. pa.a.eters a.fect the sintera.ility of the a.uminium powder, including a.mospheric dew point which is rega.ded a. one of the crucia. pa.a.eters. The objective of this work wa. to investiga.e the effect of the a.mospheric dew point on the sintera.ility of a.-14.9Si-2.4Cu-0.55Mg by studying the sintering cha.a.ters obta.ned under va.ious a.mospheric dew points. The a.uminium a.loy powder wa. pressed into tensile specimens a.d subsequently sintered in a.nitrogen a.mosphere a. 560 ℃ for 60 min with va.ied a.mospheric dew points. The results show tha. a. the dew point decrea.ed, the sintered properties were improved. The a.mospheric dew point of -38.4 ℃ is sufficient to obta.n good sintering cha.a.ters a.d it is a.hieva.le in a.commercia. furna.e.

关键词： a.uminium a.loys Sintering Mecha.ica. cha.a.terisa.ion a.mospheric dew point

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Effects of irregula.ity a.d initia. stresses on the dyna.ic response of viscoela.tic ha.f-spa.e due to a.moving loa.

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a.ta.Mecha.ica.Solida.Sinica 2017年第3期30卷 306-317页

作者： a.K. Singh a. Da. a. La.shma. a. Negi a. Cha.topa.hya. Depa.tment of a.plied Ma.hema.ics Indian Institute of Technology (Indian School of Mines) Dhanbad 826004 Jharkhand India

The present a.ticle dea.s with the stresses developed in a. initia.ly stressed irregula. viscoela.tic ha.f-spa.e clue to a.loa. moving with a.consta.t velocity a. a.rough free surfa.e. Expressions for norma. a.d shea. stresses a.e obta.ned in closed form. The substa.tia. effects of influence pa.a.eters, viz., depth （from the free surfa.e）, irregula.ity fa.tor, ma.imum depth of irregula.ity, viscoela.tic pa.a.eter, horizonta. a.d vertica. initia. stresses, a.d frictiona. coefficient, on norma. a.d shea. stresses a.e investiga.ed. Moreover, compa.a.ive study is ca.ried out for three different ca.es of irregula.ity, viz., recta.gula. irregula.ity, pa.a.olic irregula.iW a.d no irregula.ity, which is ma.ifested through gra.hs.

关键词： Viscoela.tic Irregula.ity Moving loa. Frictiona. coefficient Stresses

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The Efect of the Ea.thed Electrode Size on the Ignition Volta.e of Low-Pressure RF Ca.a.itive Discha.ge in a.gon

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Pla.ma.Science a.d Technology 2013年第9期15卷 881-884页

作者： a. a. a.OOZ M. a. a.Ma. Depa.tment of Physics College of ScienceMosul University Depa.tment of Physics College of EducationMosul University

The effect of the grounded electrode dia.eter on the ignition volta.e using 13.56 MHz in a.gon ga. is studied experimentMly. The results indica.e a.systema.ic decrea.e of the brea.down volta.e with increa.ing electrode a.ea.for the sa.e pd va.ue. No multi-va.ued brea.down volta.es a.e observed. The Pa.chen minimum is not a.fected by the electrode dia.eter a. long a. the pa.a.lel pla.e a.proxima.ion is va.id. a.modified Pa.chen equa.ion which ta.es into a.count indirect discha.ge via.the cha.ber wa.ls a. high pd va.ues gives rea.ona.le fits to the experimenta. da.a.

关键词： CCRF electrode size Pa.chen la. RF pla.ma

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