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Neura. Regenera.ion Resea.ch 2022年第9期17卷 1965-1966页

作者： Celia.Herrera.Rincon Julia.Murcia.o-brea Stefa.o Geuna Depa.tment of Biodiversity Ecology&Evolutionand ModelingData Analysis&Computational Tools for Biology Research GroupBiomathematics UnitComplutense University of MadridMadridSpain Depa.tment of Clinica. a.d Biologica. Sciences and Cavalieri Ottolenghi Neuroscience InstituteUniversity of TurinTurinItaly

The huma. body is popula.ed by a.la.ge number of microbia. colonies,with a. estima.ed 10-100 trillion *** tota. genome size of huma. microbia. colonies by fa. overwhelms the size of the host’s *** heterogenous group of microbia. colonies(prima.ily ba.teria.but a.so a.cha.a.euka.yotes a.d viruses)is referred to with the term microbiota.a.d a.though most of them popula.e the gut,microbes a.e a.so detecta.le in ma.y other orga.s of the body,especia.ly in the dista. tra.ts of the genitourina.y system a.d the *** the la.t yea.s,a. increa.ing a.ount of evidence ha. been a.cumula.ed on how the microbiota.exerts a.significa.t influence on the development a.d physiology of the huma. body.

关键词： neura. orga.s size

The roles of bone remodeling in norma. hema.opoiesis a.d a.e-rela.ed hema.ologica. ma.igna.cies

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Bone Resea.ch 2023年第2期11卷 273-291页

作者： Hengwei Zha.g Ja.e LLiesveld La.ra.MCa.vi brea CLipe Lia.ping Xing Micha.l WBecker Edwa.d MSchwa.z Shu-Chi a.Yeh Center for Musculoskeleta. Resea.ch University of Rochester Medical Center601 Elmwood AveBox 665RochesterNY14642USA Depa.tment of Pa.hology a.d La.ora.ory Medicine University of Rochester Medical CenterRochesterNYUSA Wilmot Ca.cer Center University of Rochester Medical CenterRochesterNYUSA Depa.tment of Medicine Division of Hematology/Oncology and Bone Marrow Transplantation ProgramUniversity of Rochester Medical CenterRochesterNYUSA Depa.tment of Medicine Division of Endocrinology/MetabolismUniversity of Rochester Medical CenterRochesterNYUSA Depa.tment of Orthopa.dics University of Rochester Medical CenterRochesterNYUSA Depa.tment of Medicine Division of Allergy/Immunology/RheumatologyUniversity of Rochester Medical CenterRochesterNYUSA Depa.tment of Biomedica. Engineering University of RochesterNYUSA Depa.tment of Physiology/Pha.ma.ology University of Rochester Medical CenterRochesterNYUSA

Prior resea.ch esta.lishing tha. bone intera.ts in coordina.ion with the bone ma.row microenvironment(BMME)to regula.e hema.opoietic homeosta.is wa. la.gely ba.ed on a.a.yses of individua. bone-a.socia.ed cell *** a.va.ces in intra.ita. ima.ing ha. suggested tha. the expa.sion of hema.opoietic stem cells(HSCs)a.d a.ute myeloid leukemia.cells is restricted to bone ma.row microdoma.ns during a.distinct sta.e of bone *** findings indica.e tha. dyna.ic bone remodeling likely imposes a.ditiona. heterogeneity within the BMME to yield differentia. clona. responses.a.holistic understa.ding of the role of bone remodeling in regula.ing the stem cell niche a.d how these intera.tions a.e a.tered in a.e-rela.ed hema.ologica. ma.igna.cies will be critica. to the development of novel *** a.va.ce this understa.ding,herein,we provide a.synopsis of the cellula. a.d molecula. constituents tha. pa.ticipa.e in bone turnover a.d their known connections to the hema.opoietic ***,we ela.ora.e on the coupling between bone remodeling a.d the BMME in homeosta.is a.d a.e-rela.ed hema.ologica. ma.igna.cies a.d a.ter trea.ment with bone-ta.geting *** then discuss unresolved questions a.d a.biguities tha. rema.n in the field.

关键词： remodeling homeosta.is likely

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三维后方交会

国外地质与勘测 1995年第1期 52-57页

作者： brea.,MC 徐惠莲

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物质进化论

商业周刊（中文版） 2016年第13期 79-83页

作者： Ca.oline Winter brea Souders

Thyroid Ca.tila.e Chondrosa.coma.Review: Ma.a.ement a.d Prognosis of a.Ra.e Tumor

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Interna.iona. Journa. of Otola.yngology a.d Hea. & Neck Surgery 2014年第2期3卷 57-65页

作者： a.tonio rodríguez-Va.iente a.a.a.Roldán-Fida.go Jose Ra.ón Ga.cía.Berroca. Isa.el Sa.a. Bea.riz brea Depa.tment of Neurora.iology University Hospital Puerta de Hierro Majadahonda Madrid Spain Depa.tment of Otorhinola.yngology University Hospital Puerta de Hierro Majadahonda Madrid Spain Depa.tment of Pa.hology University Hospital Puerta de Hierro Majadahonda Madrid Spain

Objective: This a.ticle is a.critica. review of the litera.ure concerning thyroid ca.tila.e chondrosa.coma.a.d is pa.ticula.ly focused on the ma.a.ement a.d prognosis of this ra.e entity. Study Design: a.review of a.l the ca.es of thyroid ca.tila.e chondrosa.coma.reported in the litera.ure up to Ja.ua.y 2013. Methods: The sea.ch wa. ca.ried out through the introduction of the MeSH terms: Chondrosa.coma. La.yngea. Ca.tila.es, Thyroid Ca.tila.e, Thera.eutics. a.l the studies rela.ed to thyroid ca.tila.e chondrosa.coma.were selected together with a.newly presented ca.e. Results: a.tota. of 47 ca.es ha.e been described in the litera.ure, a.d 35 of these include sufficient da.a.for sta.istica. a.a.ysis. The a.e of pa.ients ra.ged from 40 to 77 yea.s, with a.ma.e predilection (88.6%). The ma.n symptoms were neck ma.s a.d hoa.seness. Gra.e I a.d II tumors were most frequent. a.tota. of 13 ca.es described a. extension of the tumor beyond the thyroid ca.tila.e. The most common trea.ment wa. pa.tia. la.yngectomy (50%). a.l pa.ients who died were ma.e, with gra.e II or II-III tumor or a.socia.ed sa.coma. ha. meta.ta.es a.d received ra.iothera.y in a.dition to tota. la.yngectomy. Conclusion: Pa.ient a.e a.d tumor size does not influence the prognosis. Tumor gra.e I a.d I-II ha.e good prognoses, wherea. the prognosis is unpredicta.le in tumors between gra.e II a.d III. Pa.ients with a.socia.ed sa.coma. or meta.ta.is, ha.e a.worse prognosis. Pa.tia. la.yngectomy is a.good thera.eutic option, a.though tota. la.yngectomy is sometimes required in order to ensure complete resection.

关键词： Chondrosa.coma La.yngea. Ca.tila.es Thyroid Ca.tila.e Thera.eutics

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请用细菌洗手

商业周刊（中文版） 2019年第10期 64-69页

作者： Ca.OLINE WINTON brea SOUDERS(摄影) 杨飞(译) 不详

2009年2月的一天,外面连下了一周的雪,54岁的戴维.惠特洛克(Da.id Whitlock)在他位于马萨诸塞州坎布里奇附近的三居室公寓里打点完行装,将东西搬进他的面包车里。为了在全球范围内给他新发现的一种令他痴迷的东西申请专利,这位发明家花... 详细信息

2009年2月的一天,外面连下了一周的雪,54岁的戴维.惠特洛克(Da.id Whitlock)在他位于马萨诸塞州坎布里奇附近的三居室公寓里打点完行装,将东西搬进他的面包车里。为了在全球范围内给他新发现的一种令他痴迷的东西申请专利,这位发明家花光了自己所有的钱一将近50万美元。这是从土壤样品中采集的一种细菌,他认为这种细菌能改善皮肤病、高血压和其他健康问题。惠特洛克说:“这是我能做的最重要的事情。但是我知道我需要取得专利,否则就无法让任何人感兴趣。”

关键词：细菌洗手申请专利 2009年马萨诸塞州健康问题面包车发明家

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三维后方交会

本钢译丛 1996年第1期 48-52页

作者： brea.,MC 法维刚

传统的测量后方交会是二维交会。或者已知三个测站的坐标，观测两个水平角，或者已知两点的坐标和在待求坐标的测站上观测一个水平角和一个方位角，即可求得第四个点的坐标，本文叙述了观测一个水平角和到两已知点的竖直角，即可求得一... 详细信息

传统的测量后方交会是二维交会。或者已知三个测站的坐标，观测两个水平角，或者已知两点的坐标和在待求坐标的测站上观测一个水平角和一个方位角，即可求得第四个点的坐标，本文叙述了观测一个水平角和到两已知点的竖直角，即可求得一个点的三维坐标的几何图形和计算过程，提出迭代和直接解算两种方法。

关键词：测量后方交会三维交会

Pola.iza.ion conversion using customized subwa.elength la.er-induced periodic surfa.e structures on sta.nless steel

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Photonics Resea.ch 2022年第9期10卷 2024-2031页

作者： Ma.MOUD H.ELSHORBa.Y LUIS MIGUEL SÁNCHEZ-brea JERÓNIMO BUENCUERPO JESÚS DEL HOYO ÁNGELa.SORIa.Ga.CÍa.VERÓNICa.Pa.TOR-VILLa.RUBIa.a.EJa.DRO Sa.-BLa. a.Na.a.rodRÍGUEZ Sa.TIa.O MIGUEL OLa.ZOLa.Ja.IER a.DA Grupo Complutense deÓptica.a.lica.a Departamento deÓpticaFacultad de Ciencias FıÂsicasUniversidad Complutense de MadridPlaza de las Ciencias S.N.28040 MadridSpain Physics Depa.tment Faculty of ScienceMinia University61519 El-MinyaEgypt L’Institut Photovolta.que d’Île-de-Fra.ce(IPVF) 18 Bd Thomas Gobert91120 PalaiseauFrance Ceit-Ba.que Resea.ch a.d Technology a.lia.ce(BRTa. Manuel Lardizabal 1520018 Donostia/San SebastiánSpain Universida. de Na.a.ra TecnunManuel Lardizabal 1320018 Donostia/San SebastiánSpain

Sta.nless steel is a.ba.ic ra. ma.eria. used in ma.y *** ca. be customized by genera.ing la.er-induced periodic surfa.e structure(LIPSS)a. subwa.elength ***,we present the ca.a.ilities of a. LIPSS on sta.nless steel to modify the pola.iza.ion sta.e of the reflected ra.ia.ion a. the IR *** structures ha.e been modeled using the finite element method a.d fa.rica.ed by femtosecond la.er *** Stokes pa.a.eters ha.e been obta.ned experimenta.ly a.d a.model for the sha.e ha. been used to fit the simula.ed Stokes va.ues to the experimenta. *** birefringence of the LIPSS is a.a.yzed to expla.n how they modify the pola.iza.ion sta.e of the incoming *** find the geometry of the subwa.elength gra.ing tha. ma.es it work a. a. optica. reta.der tha. tra.sforms a.linea.ly pola.ized light into a.circula.ly pola.ized *** a.dition,the geometrica. pa.a.eters of the LIPSS a.e tuned to selectively a.sorb one of the components of the incoming light,becoming a.linea. a.ia. *** selecting the geometrica. pa.a.eters a.d orienta.ion of the fa.rica.ed LIPSS ma.es it possible to obta.n a. a.bitra.y pure pola.iza.ion sta.e when illumina.ed by a.pure linea.ly pola.ized sta.e oriented a. a. a.imuth of 45°.The overa.l reflecta.ce of these tra.sforma.ions rea.hes va.ues close to 60%with respect to the incident intensity,which is the sa.e reflectivity obta.ned for non-na.ostructured sta.nless steel fla. surfa.es.

关键词： steel la.er pola.iza.ion

Va.cula. Loops a.d Neuro-Otologic Symptoms: Is There a.y Correla.ion?

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Interna.iona. Journa. of Otola.yngology a.d Hea. & Neck Surgery 2013年第6期2卷 245-247页

作者： a.a.a.Roldán-Fida.go a.tonio rodríguez-Va.iente Fra.cisco Ma.tín González Ma.te Pinilla.a.mudena.Trinida. Bea.riz brea álva.ez Depa.tment of Otorhinola.yngology a.d Neurora.iology Puerta de Hierro University Hospital Madrid Spain

Objective: To determine the rela.ionship between va.cula. loops in the interna. a.ditory ca.a. a.d otologic symptoms. Methods: We performed a.retrospective study, with a.systema.ic review of the litera.ure a.d a.a.yzed the ma.netic resona.ces ima.ing (MRI) of 91 pa.ients a.tended in the ENT depa.tment since a.ril to June 2013, in order to correla.e ra.iologica. findings with otologic symptoms. Results: Va.cula. loops were seen in the interna. a.ditory ca.a. of pa.ients without clinica. symptoms;however a. a.socia.ion wa. found between the presence of va.cula. compression of the eighth nerve displa.ed on MRI a.d the presence of sensorineura. hea.ing loss a.d tinnitus. No a.socia.ion wa. found between vertigo a.d va.cula. loops. Conclusion: The presence of va.cula. loops in the interna. a.ditory ca.a. ma. be a. incidenta. finding in MRIs of pa.ients without clinica. symptoms. However, in pa.ients with tinnitus or sensorineura. hea.ing loss tha. is unexpla.ned by other clinica. pa.hologies, these ma. be correla.ed with the existence of va.cula. loops which compress the eighth cra.ia. nerve or conta.t the bone wa.l of the interna. a.ditory ca.a.. Further studies involving a.la.ger number of pa.ients a.e required to a.cura.ely eva.ua.e the a.socia.ion between these symptoms a.d va.cula. loops.

关键词： Va.cula. Loop a.teria. Loop Interna. a.ditory Ca.a. Tinnitus Dea.ness Vertigo

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Dea.h of Dea.h Note？

China.Interna.iona. Business 2007年第6期 46-46页

作者： Jennifer brea

a.new ca.pa.gn a.a.nst illega. horror ma.a.ines shows a.resilient ma.ket a.ong young people for a.l things morbid

关键词：中国文化市场恐怖小说恐怖游戏非法出版物