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Microfilament-binding properties of N-terminal extension of the isoform of smooth muscle long myosin light chain kinase

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Cell research 2006年第4期16卷 367-376页

作者： Chun Xiang Yang~(1,3,*) Hua Qun Chen~(2,*) Chen Chen~1 Wei Ping Yu~3 Wen Cheng Zhang~1 Ya Jin Peng~1 Wei Qi He~1 Dong Mei Wei~1 Xiang Gao~1 Min Sheng Zhu~(1,4.~1Model Animal research center and National Key Lab of Medicine,Nanjing university,Nanjing 210061,China,~2College of Life science,Nanjing Normal Unversity,Nanjing 210097,China ~3Medical College,Southeast university,Nanjing 210096,China ~4.uadong research Institute for Medical Biotechnics,Nanjiang 210002,China ModelAnimalresearchcenterandNationalKeyLabofMedicine NanjingUniversityNanjing210061China CollegeofLifescience NanjingNormalUniversityNanjing210097China MedicalCollege SoutheastUniversityNanjing210096China

Myosin light chain kinases (MLCK) phosphorylate the regulatory light chain of myosin Ⅱ in thick filaments andbind to F-actin-containing thin filaments with high *** ability of short myosin light chain kinase (S-MLCK)to bind F-actin is structurally attributed to the DFRXXL regions in its *** long myosin light chain kinase(L-MLCK) has two additional DFRXXL motifs and six lg-like modules in its N-terminal *** six lg-likemodules are capable of binding to stress fibers *** results from the imaging analysis demonstrated thatthe first two intact lg-like modules (21g) in N-terminal extension of L-MLCK is the minimal binding module required formicrofilament *** assay confirmed that F-actin was able to bind *** of2lg peptide weresimilar for myofilament or pure *** binding affinities were slightly lower than 5DFRXXL peptide as *** to DFRXXL peptides,the 2Ig peptide also caused efficient F-actin bundle formation in *** theliving cell,over-expression of 2Ig fragment increased"spike"-like protrusion formation with over-bundled *** suggest that L-MLCK may act as a potent F-actin bundling protein via its DFRXXL region and the 2Ig region,implying that L-MLCK plays a role in cytoskeleton organization.

关键词： MLCK F-actin bundle Ig-like module

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A Molecular Dynamics Study on the (1120) Domain Boundary Structures in Epitaxial Wurtzite GaN

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Journal of Materials science & Technology 1999年第4期15卷 328-330页

作者： Shaoqing WANGt Yuanming WANG and Hengqiang YE(Laboratory of Atomic imaging of Solids, Institute of Metal research, Chinese Academy of sciences,Shenyang 110015, China)To whom correspondence should be addressedE-mail: sqwang@*** Laboratory of Atomic imaging of Solids Institute of Metal Research Chinese Academy of Sciences Shenyang 110015 China

A computer program has been developed for the moIlcular dynamics calculation of ionic orstrong-ionic covalent systems. Ewald summation algorithm and Keating potentiaI model areadopted to calculate the long-range Coulomb interaction and the short-range bonding forces,respectively. A theoretical study on the domain boundary structures in epitaxial wurtzite GaN film is accomplished with the program. The calculation result is used in the structure formationexplanation of an interesting defect observed by HREM experiment.

关键词： Rev Domain Boundary Structures in Epitaxial Wurtzite GaN A Molecular Dynamics Study on the

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THE EFFECT OF IMU INACCURACIES ON AIRBORNE SAR imaging

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Journal of Electronics(China) 2011年第Z1期 409-418页

作者： Mao Yongfei* ** Xiang Maosheng* Wei Lideng* Han Songtao*** *(National Key Laboratory of science and Technology on Microwave imaging, Institute of Electronics, Chinese Academy of sciences, Beijing 100190, China) **(Graduate university of Chinese Academy of sciences, Beijing 100039, China) ***(Beijing Aerospace Control center, Beijing 100094. China)

When using motion compensation approaches based on the measurement of motion sensors, the residual uncompensated motion errors due to measurement instrument inaccuracies contribute to phase errors and hence degrade Synthetic Aperture Radar (SAR) images. This paper presents a model to compute the phase error caused by Inertial Measurement Unit (IMU) measurement inaccuracies. By analyzing SAR motion compensation method and the effect of lever arm, this model derives the con-tribution of each term of IMU inaccuracies towards the residual uncompensated motion errors and provides a method to calculate each order of the residual phase error. According to the model, com-puted results of the airborne X-band SAR system with POS AV510 accord closely with the actual image quality.

关键词： Synthetic Aperture Radar (SAR) Inertial Measurement Unit (IMU) Motion compen-sation Phase error

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Molecular Dynamics Simulation of Zero-Fluence and Low-Bombarding-Energy ^(63)Cu-^(65)Cu Sputtering

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Journal of Materials science & Technology 1999年第2期15卷 184-186页

作者： Liping ZHENG Shi QIU and Yukui ZHOU (Shanghai Institute of Nuclear research, Chinese Academy of sciences, P.O.Box800-204. Shanghai 201800,China)Hisheng LI(Lab. of Atomic imaging of Solids, Institute of Metal research Chinese Academy of sciences, Shenyang Shanghai Institute of Nuclear research Chinese Academy of Sciences P.O.Box800-204 Shanghai 201800 China Lab. of Atomic imaging of Solids Institute of Metal Research Chinese Academy of Sciences Shenyang 110015 China

A molecuIar dynamics simulation has been used to study zero-fluence and low- bombarding63Cu-65Cu sputtering. Calculations show that the isotopic ratios at both θ≤35° and energy 63Cu-65Cu sputtering. Calculations show that the isotopic ratios at both θ≤35° and θ >35°, and the total isotopic ratio increase when the bombarding energy decreases. This result might impty the existence of the bombarding-energy-dependent momentum asymmetry.

关键词： Simulation Cu Sputtering Molecular Dynamics Simulation of Zero-Fluence and Low-Bombarding-Energy

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XMM-Newton observation of the eclipsing binary Algol

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research in Astronomy and Astrophysics 2011年第4期11卷 457-470页

作者： Xue-Juan Yang Fang-Jun Lu Bemd Aschenbach Li Chen Faculty of Materials Optoelectronics and Physics Xiangtan University Xiangtan 411105China Particle Astrophysics center Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China Max-Planck-Institut fur Extraterrestrische Physik 85741 Garching Germany Department of Astronomy Beijing Normal University Beijing 100875 China

We present an XMM-Newton observation of the eclipsing binary Algol which contains an X-ray dark B8V primary and an X-ray bright K2IV secondary. The observation covered the optical secondary eclipse and captured an X-ray flare that was eclipsed by the B star. The XMM-Newton European Photon imaging Camera and Reflection Grating Spectrometer spectra of Algol in its quiescent state are described by a two-temperature plasma model. The cool component has a temperature around 6.4. 106 K while that of the hot component ranges from 2 to 4.0× 107 K. Coronal abundances of C, N, O, Ne, Mg, Si and Fe were obtained for each component for both the quiescent and the flare phases, generally with upper limits for S and Ar, and upper limits for C, N, and O from the hot component. F-tests show that the abundances do not need to be different between the cool and the hot component and between the quiescent and the flare phase with the exception of Fe. Although the Fe abundance of the cool component remains constant at -0.14. the hot component shows an Fe abundance of -0.28, which increases to -0.4. during the flare. This increase is expected from the chromospheric evaporation model. The absorbing column density NH of the quiescent emission is 2.5 - 1020 cm-2, while that of the flare-only emission is significantly lower and consistent with the column density of the interstellar medium. This observation substantiates earlier suggestions of the presence of X-ray absorbing material in the Algol system.

关键词： stars abundance -- star binaries eclipsing -- stars flare -- stars indi-vidual Algol

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多基站ISAR平面转台目标成像模型与仿真研究

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系统仿真学报 2011年第9期23卷 1921-1924,1931页

作者：云日升朱迪康雪艳中国科学院空间科学与应用研究中心北京100190

建立了匀角速度平面转动目标和匀角加速度平面转动目标的多基站ISAR平面转台目标模型,给出了多基站ISAR平面转台目标的成像算法,同时分析了多基站ISAR平面转台目标成像约束。通过在多基站ISAR平面转台目标成像模型的基础上构造多基站方... 详细信息

建立了匀角速度平面转动目标和匀角加速度平面转动目标的多基站ISAR平面转台目标模型,给出了多基站ISAR平面转台目标的成像算法,同时分析了多基站ISAR平面转台目标成像约束。通过在多基站ISAR平面转台目标成像模型的基础上构造多基站方位向多普勒方程组和距离向投影方程组,实现了对目标散射点位置参数和运动参数的准确估计。仿真实验验证了多基站ISAR平面转台模型和成像算法。

关键词：多基站逆合成孔径雷达平面转台成像

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反射式扫描近场光学显微镜及其成像

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中国激光 1998年第9期25卷 852-858页

作者：王刚赵钧刘静勇张培林清华大学现代应用物理系和单原子分子测控中心

介绍了一种光纤探针同时作为光源和探测器的反射式扫描近场光学显微镜，该装置通过采用相干探测、偏振分光等技术克服了该类显微镜所普遍面临的噪声背景干扰问题，具有较高的光学信噪比，并通过样品纵向振动调制锁相实现了对样品表面光... 详细信息

介绍了一种光纤探针同时作为光源和探测器的反射式扫描近场光学显微镜，该装置通过采用相干探测、偏振分光等技术克服了该类显微镜所普遍面临的噪声背景干扰问题，具有较高的光学信噪比，并通过样品纵向振动调制锁相实现了对样品表面光强梯度信号的探测成像，进一步改善了成像质量。成像研究表明该装置可对近场衰逝分量进行有效探测并实现了超衍射极限成像。

关键词： SNOM 反射模式衰逝波相干探测光学显微镜

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A COMPREHENSIVE INVESTIGATION ON A PECULIAR DEFECT IN WURTZITE GaN FILM

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Acta Metallurgica Sinica(English Letters) 1999年第4期12卷 327-333页

作者： S.Q.Wang1 ,2) and H.Q.Ye1) 1) Laboratory of Atomic imaging of Solids,Institute of Metal research , The Chinese Academy of sciences, Shenyang 110015 ,China 2)Department of Materials science and Metallurgy , {4. of Cambridge, Cambridge CB2 3QZ, UK

Apeculiar crystal defect was observed by experiment of high resolution electron microscopy( HREM) .It wasidentifiedtoformed bytwothreading dislocationsand asegmentof(11 20) domain boundary. An atomicstructure model was proposed for the anomalous defect. Theresultofthe weak beam experimentofelectron microscopeaffirmedthesuggested *** GaN(11 2 0) domain boundaries werestudied by Molec ular Dynamicscalculations. Thetheoreticalresultsshowedthatthelike atom bonding domain boundary, whichcomposesthe main partofthe peculiar defect, has much higher formationenergy than itcounterpartof unlike atom bonding domain boundary. Theoutcome providesanotherevidenceforthesuggested model.

关键词： HREM weak beam electron microscopy crystal defect Wurtzite GaN molecular dynamics

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Fast bowtie effect elimination for MODIS L1B data

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The Journal of China Universities of Posts and Telecommunications 2010年第1期17卷 120-126页

作者： REN Rui-zhi,GUO Shu-xu,GU Ling-jia College of electronic science and engineering,Jilin university,Changchun 130012,China College of electronic science and engineering Jilin University Changchun 130012 China

The bowtie effect refers to geometry distortions for the moderate resolution imaging spectrum-radiometer （MODIS） level 1B （L1 B） data. Till now, to eliminate the bowtie effect, numerous methods are proposed. However, most of them have limitations in computation efficiency. Through a comparative study of existing methods, this article puts forward a fast method to eliminate the bowtie effect using the ephemeris data. In this method, the rough positions of overlapping data are first detected. Because of the influence caused by the instrarnent characters and the earth＇s curvature, the positions of overlapping data need to be rectified to obtain more precise results. The optimal rectification method used in this article is selected by comparing three methods. By using the optimal method, the rectified MODIS data can be obtained. The experiments demonstrate that the bowtie effect can be eliminated in less than 1 s. In contrast, other traditional methods spend at least 3 s, thus the proposed method is faster and more effective.

关键词： bowtie effect MODIS bilinear interpolation overlapping data rectification

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INVESTIGATION ON 1/3[111] FRANK LEDGE DISLOCATIONS ATα_2/γINTERFACE IN HOT-DEFORMED Ti-4.Al-10Nb ALLOY

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Acta Metallurgica Sinica(English Letters) 1997年第4期10卷 323-328页

作者： J.G WanG L.C Zhang G.L. Chenand HQ. Ye(State Key Laboratory for Advanced Metals and Materials, Unborsity of science and Technology Beijing,Beijing 100083, China)(Laboratory of Atond imaging of Solids, Institute of Metal research, Chinese Academy of Scienc Univ of science and Technology Beijing Beijing China

The dislocation ledges at the α2/7 intedece in a hot-dejormed Ti-4.Al-10N alloywere analyzed by high-resolution tmnsmission electron microscopy. A new type ofdislocation ledge containing 1/3[111] Frank partial was found. The height of the ledgestDas always three [111]γplanes. The Burpers vectore of these diBlocation ledges weredetermined to be 1/2[110] and 1/2<101] corresponding to the 90 dey. and 30 *** partials at noral ledges, i.e. 90 dep. ShockIey Partial dislocation +1/3[111]Frank partial dislocation; and 30 deg. Shockley partial dislocation + 1/3[111] Frankparfial dislocations. The jormation mechanism of this new tare of dislocation ledgewas discussed.

关键词： titanium aluminide thermomechanical treatment phase interface tmnsmission electron microscopy

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