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Effect of Inhalational Anesthetics on Cytotoxicity and Intracellular Calcium Differently in Rat Pheochromocytoma Cells (PC12.

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Journal of Huazhong University of science and technology(Medical sciences) 2008年第1期28卷 104-109页

作者：王秋筠李克忠姚尚龙 department of Anesthesiology Union Hospital Tongji Medical College Huazhong University of Science and Technology

Isoflurane, a commonly used inhaled anesthetic, induces apoptosis in rat pheochromocytoma cells （PC12. in a concentration- and time-dependent manner with unknown mechanism. We hypothesized that isoflurane induced apoptosis by causing abnormal calcium release from the endoplasmic reticulum （ER） via activation of inositol 1,4.5-trisphosphate （IP3. receptors. Alzheimer＇s presenilin-1 （PS 1） mutation increased activity of IP3.receptors and therefore rendered cells vulnerable to isoflurane-induced cytotoxicity. Sevoflurane and desflurane had less ability to disrupt intracellular calcium homeostasis and thus being less potent pared the cytotoxic effects of various inhaled to cause cytotoxicity. This study examined and com-anesthetics on PC12.cells transfected with the Alzheimer＇s mutated PS 1 （L286V） and the disruption of intracellular calcium homeostasis. PC 12.cells transfected with wild type （WT） and mutated PS 1 （L286V） were treated with equivalent of 1 MAC of isoflurane, sevoflurane and desflurane for 12.h. MTT reduction and LDH release assays were performed to evaluate cell viability. Changes of calcium concentration in cytosolic {4. （[Ca^2＋]c） were determined after exposing different types of cells to various inhalational anesthetics. The effects of IP3.receptor antagonist xestospongin C on isoflurane-induced cytotoxicity and calcium release from the ER in L286V PC12.cells were also determined. The results showed that isoflurane at 1 MAC for 12.h induced cytoxicity in L286V but not WT PC12.cells, which was also associated with greater and faster elevation of peak [Ca^2＋]c in L286V than in the WT cells. Xestospongin C significantly ameliorated isoflurane cytotoxicity in L286V cells, as well as inhibited the calcium release from the ER in L286V cells. Sevoflurane and desflurane at equivalent exposure to isoflurane did not induce similar cytotoxicity or elevation of peak [Ca^2＋]c in L286V PC 12.cells. These results suggested that isoflurane induced cytoxicity by par

关键词： inhalational anesthetics cytotoxicity calcium

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衬底对PTCDA薄膜结构与电荷输运特性的影响

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发光学报 2012年第3期33卷 334-340页

作者：杨汀谢吉鹏范国莹吕文理彭应全兰州大学物理学院微电子研究所甘肃兰州730000 空军大连通信士官学校基础部辽宁大连116600 兰州大学磁学与磁性材料教育部重点实验室甘肃兰州730000

在不同导电衬底(Au,Al和ITO)上制备了PTCDA薄膜,用XRD和AFM技术研究了PTCDA薄膜的结构和表面形貌。结果表明,薄膜中的大部分PTCDA分子平面与衬底不平行,这表明薄膜垂直方向的电流传导将以电子传输为主;在ITO和Au衬底上生长的PTCDA薄膜... 详细信息

在不同导电衬底(Au,Al和ITO)上制备了PTCDA薄膜,用XRD和AFM技术研究了PTCDA薄膜的结构和表面形貌。结果表明,薄膜中的大部分PTCDA分子平面与衬底不平行,这表明薄膜垂直方向的电流传导将以电子传输为主;在ITO和Au衬底上生长的PTCDA薄膜晶粒排列规则,在薄膜垂直方向呈现出较好的电子传输性能;而在Al衬底上生长的PTCDA薄膜晶粒排列无序,电子传输性能差。通过制备单层结构有机薄膜器件,研究了PTCDA薄膜垂直方向的电子迁移率。综合应用金属-有机界面的热电子发射理论和有机层体内空间电荷限制传导理论,并考虑电场强度对迁移率变化的影响,对ITO/PTCDA/Al器件的电流密度-电压曲线进行拟合,得到ITO衬底上生长的PTCDA薄膜在垂直方向随电场强度变化的电子迁移率数值。

关键词：苝四甲酸二酐有机半导体迁移率电荷传输

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Raman Spectrum of Rhombohedral Neodymium-Aluminum Borate

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Journal of Modern Transportation 1998年第1期15卷 102-107页

作者：谢宁施善

The Raman spectrum of rhombohedral NdAl 3.(BO 3. 4.(NAB) is recorded and interpreted. A factor group analysis of the NAB space group shows that there are 21A 1 and 59E Raman active modes. A discussion of the assignment of the individual Raman lines is given. The splitting predicted by factor group for the internal modes of (BO 3. 3. anion are observed and interpreted.

关键词： Raman spectrum neodymium aluminum borate self activated laser materials

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Synthesis,Crystal Structure and thermal decomposition mechanism of the complex [Sm(p-BrBA)3.ipy·H2O]2·H2O

Synthesis,Crystal Structure and thermal decomposition mechan...

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中国化学会第五届全国结构化学学术会议

作者： H.Y.Zhang~(1,2) J.J.Zhang~(1*) S.L.Xu~(1,2) N.Ren~3.L.Tian~(1,2) J.H.Bai~4.(1 Experimental Center,Hebei Normal University,shijiazhuang 050016 P.R.china.) (2 College of Chemistry& Material science,Hebei Normal University,Shijiazhuang 050016 P.R.china) (3.department of Chemistry,Handan College,Handan 056005 P.R.china) 4.department of Compute,Hebei Normal College of science and technology,Qinhuangdao,066600 P.R.china)

A binuclear samarium(Ⅲ)complex with p-bromobenzoic acid and 2,2′-bipyridine [Sm(p-SrBA)bipy-HO]·HO has been synthesized and characterized by elemental analysis,UV, IR and TG-DTG *** structure of the complex was established by single crystal X-ray *** crystallized in triclinic,space group PT with a=8.24.6(7),b=13.3.1}3.10),c= 15.903.(13.,α=73.9160(10),β=78.963.(10),γ=74.4.70(10),Z=1,D=1.94. g·cm,F(000)= *** carboxylate groups are bonded to the samarium ion in two modes:bidentate bridging,

关键词： Samarium complex p-bromobenzoic acid 2,2’-bipyridine Crystal structure Thermal decomposition mechanism

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Precise U-series Dating of Coral Reefs from the South china Sea and the High Sea Level during the Holocene

Precise U-series Dating of Coral Reefs from the South China ...

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中国科学院地质与地球物理研究所2003.术年会

作者： Z.B.Ma+,J.L.Xiao+,X.T.Zhao+,Z.C.Peng++,M.Xia+, G.P.Zhang§,Z.R.Wang++,and Z.S.An+ +Institute of Geology and Geophysics Chinese Academy of sciences Beijing 100029,china ++department of Earth and {3. sciences University of science and technology of china Hefei 23.026,china§Institute of Remote Sensing Application Chinese Academy of sciences Beijing 100101,china +Institute of Earth Environment Chinese Academy of sciences Xi’an 710054.china

Coral reefs formed along the southern coast of Hainan Island are one of the most developed Holocene fringing reefs in *** present new precise Th ages of coral reefs collected from the Shuiweiling section in the southern coast of the Hainan Island,Dengloujiao in the southwest of the Leizhou Peninsula,and the Chenhang Island and Jinyin Island of the Xisha(Paracel) Islands in the South china *** the high-precision U-series dates and stratigraphic evidence,the timing and character of the sea-level variations of the middle-Holocene in study region are examined: The results show that a flourishing period of coral reef flats in the South china Sea and along its northern coasts appeared in ca.6800 to 5800 a *** is 650 to 950 years earlier than the previous C dates(6150-4.50 a).The sea level relative to the nor thern coasts of South china Sea was 3.to 4.m or more higher than that of the present during this period.

关键词： South china Sea Holocene coral reefs TIMS dating sea-level changes

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ON CERTAIN CLASSES OF MAXIMAL SUBGROUPS IN PROJECTIVE SPECIAL UNITARY GROUPS OVER FINITE FIELDS

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science in china,Ser.A 1982年第8期 808-815页

作者：李尚志查建国 department of Mathematics University of science and technology of china Hefei

All maximal subgroups in PSU (n, q~2)(n≥3. containing T-subgroups are determined in thispaper, where a T-subgroup is meant the subgroup formed by all unitary transvections in a certaindirection. All the possible types of these maximal subgroups cover: the stabilizer of a totally iso-tropic subspace of the underlying space V, the stabilizer of a non-singular subspace of V of dimensionless than 1/2 dim V, the stabilizer of a decomposition of V into some mutually orthogonal non-singular subspaces of the same dimension (with a few exceptions), PS_p(n,q) or PS_p(n, q) Z, embed-ded naturally in PSU(n, q~2) for even n, and a particular type for PSU(6,4..

关键词： ON CERTAIN CLASSES OF MAXIMAL SUBGROUPS IN PROJECTIVE SPECIAL UNITARY GROUPS OVER FINITE FIELDS line

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Virtual-Leader-follower Structure and Finite-time Controller based Cooperative Control of Multiple Autonomous Underwater Vehicles

Virtual-Leader-follower Structure and Finite-time Controller...

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第24.中国控制与决策会议

作者： ZHOU Zhong-Hai 1, 2, 3.YUAN Jian 2, 3. ZHANG Wen-Xia 4.ZHAO Jin-Ping 1 (1. College of Physical and Environmental Oceanography, Ocean University of china, Qingdao, 2661002. Shandong Provincial Key Laboratory of Ocean Environment Monitoring technology, Qingdao, 2660013. Institute of Oceanographic Instrumentation of Shandong Academy of {3., Qingdao, 266001 4.Mechanical & Electrical Engineering department, Qindao College, Qingdao Shandong, 266016)

The formation control for large-scale multiple autonomous underwater vehicles is investigated. A formation control scheme to combinate leader-follower with virtual structure is introduced;AUVs with underwater communication rage constraints are divided into some clusters according to their relative postions in space, and leaders in all clusters can track their desired trajectories based on virtual structure;followers within all clusters follow the corresponding leader as their desired tracking trajectory. We realize the larege-scale formation control with the proposed formation scheme and the finite-time controller proposed in our previous work. Numerical simulation results show the effectiveness of the control strategy.

关键词： Autonomous Underwater Vehicle Large-scale Formation Control Virtual-leader-follower Hierarchical Structure Feedback Linearization, Finite time

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不动点集为RP(2)∪L^1(p)的对合

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数学的实践与认识 2002年第5期32卷 863-866页

作者：姚立张世民刘喜波王玉苏河北经贸大学数学与统计学院石家庄050063 河北科技大学计算中心石家庄050054 北方工业大学经济管理学院北京100041 石家庄职业技术学院基础部石家庄050081

(M3. k,T)是在光滑闭流形上的一个非平凡光滑对合 ,它的不动点集为 RP(2 )∪ L 1 (p ) .本文给出了带对合的流形 (M3. k,T)

关键词：不动点集透镜空间全Stiefel-Whitney类对合协边光滑闭流形实射影空间

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双重电流片和日冕瞬变

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Chinese Journal of Astronomy and Astrophysics 1986年第4期 312-316页

作者：胡友秋王延群中国科学技术大学地球和空间科学系

当背景磁场在日冕中存在零磁场线时,反向新磁通量的喷发将会产生双重电流片,包括零场区附近的磁场受到挤压而形成的横向电流片和新喷发场、原背景场之间形成的拱形电流片、本文用一对线偶极子来模拟背景场,用一对线磁荷来模拟反向喷发场... 详细信息

当背景磁场在日冕中存在零磁场线时,反向新磁通量的喷发将会产生双重电流片,包括零场区附近的磁场受到挤压而形成的横向电流片和新喷发场、原背景场之间形成的拱形电流片、本文用一对线偶极子来模拟背景场,用一对线磁荷来模拟反向喷发场,讨论了上述双重电流片的形成和演变过程。在电流片形成过程中,物质将向电流片集中。拱形电流片物质主要来自过渡层和光球层,并通过辐射损失进一步冷却,形成低温日珥环;横向电流片的物质则全部来自日冕,从而形成高温日冕环。以上结果可用来解释1984.4.14.观测到的日冕瞬变。

关键词：日地空间太阳磁场电流片

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A new method for the derivation of the closed nets in the phase diagram space of *** absent phase substitution method

A new method for the derivation of the closed nets in the ph...

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中国科学院地质与地球物理研究所2004.术年会

作者： J.HU~(1,2),H.YIN~2 AND Z.DUAN~(1,3. 1 The Key Laboratory of Mineral Resources,Institute of Geology and Geophysics,Chinese Academy of sciences,Beijing 100029,china 2 College of Material and Biological Engineering Chengdu University of technology,Chengdu 610059,china 3.{4. of Chemistry,03.4},University of California,San Diego,La Jolla,CA 9212.,USA

A new convenient combinatorial method is developed here to derive the invariant points in multisystem closed nets - the absent phase substitution(APS) *** substantially simplifies the derivation of the closed nets in multisystems with many components and *** the multisystems whose total phase number(N)≤twice the number of the absent phases(m) in an invariant assemblage,the method can yield regular closed nets with or without globally absent phases;for other multisystems,the method can yield the regular closed nets with globally absent *** examples,the APS method was used to predict:(1) the regular closed nets of unary to quinary n + 4.phase multisystems,unary 6-phase multisystem and ternary 8-phase multisystem;(2) the basic properties of the regular closed nets of the quaternary and quinary multisystems with n + 4.and n + 5 *** multisystems were chosen to demonstrate how to select a realistic closed net from the numerous possible closed nets of a complex multisystem,and how to derive a realistic partially closed-net,closed-net-diagram and the related realistic *** of our APS method for the derivation of complicated closed nets with other methods indicate that this method is much simpler and more efficient.

关键词： closed net invariant point multisystem phase diagram the absent phase substitution method

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