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New Receiving Mode of Extinction for Determining Particle Size and Density without Convex Lens

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Chinese Journal of Lasers 2002年第1期11卷 46-51页

作者： WU Weiliang CHEN Hanping (school of Power and Energy Engineering, shanghai Jiao Tong university, shanghai 200030, china) CAI Xiaoshu WANG Naining (school of Power and Energy Engineering, university of shanghai for science and technology, shanghai 2 school of Power and Energy Engineering Shanghai Jiao Tong University 上海 200030 school of Power and Energy Engineering University of Shanghai for Science and Technology 上海 200093

In this article a new receiving mode for scattering light by particle is theoretically discussed. Using this receiving mode the convex lens can be omitted during determining the extinction of particle. Therefore the extinction coefficient of sphere particles is redefined by extrapolating the conventional one. In terms of the calculation results of light scattering the definition of near-field extinction coefficient of a swarm particle is depicted. Through the error analysis it is proved that the error coming from the new definition of extinction coefficient is acceptable for engineering application. In addition, a technique for determining the particle size and density is presented in this article and the advantage using this receiving mode is described.

关键词： extinction of particle light scattering fluctuation method particle size particle density

Induction of liver cytochrome P450 1A2 expression by flutamide in rats

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Acta Pharmacologica Sinica 2005年第11期26卷 1382-1386页

作者： Hai-xue WANG, Xiao LIU, Chang-jiang XU, Xiao-chao MA~3, Jian-er LONG~4, Duan LI~(4,5) ~2 Department of Pharmacology, school of pharmacy, Fudan university, shanghai 200032, china ~3 State Key Laboratory of Drug Research, shanghai Institute of Biological sciences, shanghai Institute of Materia Medica, Chinese Academy of sciences, shanghai 200031, china ~4 Institute of Molecular Virus, school of Basic Medical science, Fudan university, shanghai 200031, china Department of Pharmacology School of Pharmacy Fudan University Shanghai China State Key Laboratory of Drug Research Shanghai Institute of Biological Sciences Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai China Institute of Molecular Virus School of Basic Medical Science Fudan University Shanghai China

Aim: To investigate the modulation of liver cytochrome P450 1A2 (CYP1A2) expression by giving flutamide to adult rats. Methods: Rats were given 50, 100, and 200 mg/kg po of flutamide for 2 weeks. Liver CYP 1A2 mRNA was measured using reverse transcription-polymerase chain reaction. CYP1A2 protein was detected using immunoblotting. CYPl A2 activity was assayed using high performance liquid chromatography, with caffeine as the CYPl A2 substrate. Results: CYP1A2 mRNA levels after flutamide treatment at 100 mg/kg and 200 mg/kg were, respectively, 1.86 and 3.11-fold higher than those of the control. Correspondingly, CYP1A2 protein increased 1.78 and 2.89-fold and CYPl A2 activity increased approximately 1.65 and 2.83-fold, respectively, relative to controls. Flutamide treatment at 50 mg/kg had no significant effect on CYP1A2 mRNA, protein, or enzyme activity. Conclusion: Giving rats flutamide induced liver CYP1A2 expression in a dose-dependent manner.

关键词： flutamide cytochrome P450 1A2 induction

Global optimization of tool path for five-axis flank milling with a cylindrical cutter

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science china(Technological sciences) 2009年第8期52卷 2449-2459页

作者： DING Han1 & ZHU LiMin2 1 State Key Laboratory of Digital Manufacturing Equipment and technology, Huazhong university of science and technology, Wuhan 430074, china 2 school of Mechanical Engineering, shanghai Jiao Tong university, shanghai 200240, china State Key Laboratory of Digital Manufacturing Equipment and technology Huazhong University of Science and Technology Wuhan China school of Mechanical Engineering Shanghai Jiao Tong University Shanghai China

In this paper, optimum positioning of cylindrical cutter for five-axis flank milling of non-developable ruled surface is addressed from the perspective of surface approximation. Based on the developed interchangeability principle, global optimization of the five-axis tool path is modeled as approximation of the tool envelope surface to the data points on the design surface following the minimum zone criterion recommended by ANSI and ISO standards for tolerance evaluation. By using the signed point-to-surface distance function, tool path plannings for semi-finish and finish millings are formulated as two constrained optimization problems in a unified framework. Based on the second order Taylor approximation of the distance function, a sequential approximation algorithm along with a hierarchical algorithmic structure is developed for the optimization. Numerical examples are presented to confirm the validity of the proposed approach.

关键词： five-axis flank milling tool path optimization tool axis trajectory surface surface approximation distance function minimax optimization

Research on Vibration Properties of the Drill-punch Mechanism for Taphole Drill

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Journal of university of science and technology Beijing 2001年第4期8卷 311-313页

作者： Jianping Liu, Yongfang Liao 1) Mechanical Engineering school, university of science and technology Beijing. Beijing 100083, china 2) shanghai Baoshan Iron & Steel Corporation. shanghai 201914, china Mechanical Engineering school University of Science and Technology Beijing Beijing 100083 China shanghai Baoshan Iron and Steel Corporation Shanghai 201914 China

A new type taphole drill was designed. The vibration properties of them drill-punch mechanism for the new type taphole drill were researched, the laws of its inherent characteristics were found. The measures to add punch amplitude and to reduce traverse vibration were put forward. The result showed that decreasing the frequency of vibration motors or increasing the stiffness of springs, and increasing excitation force can improve the vibration properties of the properties of the drill-punch mechanism.

关键词： taphole drill equipment in the cast house vibrating machinery

Organocatalytic enantioselective Michael addition reactions of fluoromalonates with α,β-unsaturated aldehydes

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science china Chemistry 2010年第1期53卷 135-139页

作者： LI Hao1,JI YaFei2,LI Jian2,ZHANG ShiLei1,YU ChenGuang1 & WANG Wei1,2 1 Department of Chemistry and Chemical Biology,university of New Mexico,Albuquerque,NM 87131-0001,USA 2 Department of Pharmaceutical sciences,school of pharmacy,east china university of science and technology,shanghai 200237,china Department of Chemistry and Chemical Biology University of New Mexico Albuquerque USA Department of Pharmaceutical sciences School of Pharmacy East China University of Science and Technology Shanghai China

A new organocatalytic enantioselective Michael addition of α-fluoromalonate to enals has been *** process is efficiently catalyzed by readily available chiral diphenylpyrolinol TES ether under mild reaction condition... 详细信息

关键词： organocatalysis α β-unsaturated aldehydes chiral fluorinated compounds Michael addition

Effect of MePEG molecular weight and particle size on in vitro release of tumor necrosis factor-α-loaded nanoparticles

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Acta Pharmacologica Sinica 2005年第2期26卷 242-249页

作者： Chao FANG,Bin SHI,Yuan-ying PEI~2 Department of Pharmaceutics,school of pharmacy,Fudan university,shanghai 200032,china Department of Pharmaceutics School of Pharmacy Fudan University Shanghai China

Aim:To study the in vitro release of recombinant human tumor necrosis factor-alpha(rHuTNF-α)encapsulated in poly(methoxypolyethyleneglycol cyanoacry-late-co-n-hexadecyl cyanoacrylate)(PEG-PHDCA)nanoparticles,and investigatethe influence of methoxypolyethyleneglycol(MePEG)molecular weight and par-ticle ***:Three sizes(approximately 80,170,and 240 nm)of PEG-PHDCA nanoparticles loading rHuTNF-α were prepared at different MePEG mo-lecular weights(Mr=2000,5000,and 10000)using the double emulsion *** in vitro rHuTNF-α release was studied in PBS and rat ***:Ahigher burst-release and cumulative-release rate were observed for nanoparticleswith higher MePEG molecular weight or smaller particle size.A decreased cu-mulative release of rHuTNF-α following the initial burst effect was found in PBS,while the particle sizes remained constant and MePEG *** contrast,inrat plasma,slowly increased cumulative-release profiles were obtained after theburst *** a 5-h incubation in rat plasma,more than 50% of the PEG-PHDCA nanoparticles ***:The MePEG molecular weightand particle size had an obvious influence on rHuTNF-α release,rHuTNF-αreleased from PEG-PHDCA nanoparticles in a diffusion-based pattern in PBS,but in a diffusion and erosion-controlled manner in rat plasma.

关键词： tumor necrosis factor-alpha stealth nanoparticles polyethylene glycols poly(methoxypolyethyleneglycol cyanoacrylate-con-hexadecyl cyanoacrylate)

A Quick Algorithm for Mining Exceptional Rules

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Journal of Systems Engineering and Electronics 2002年第2期13卷 71-77页

作者： Sun Haihong , Jiang Hong , Tang Jing & Yang Bingru( Department science and technology, Bank of shanghai, shanghai 200010, P. R. china Information Engineering school, university of science and technology, Beijing 100083, P. R. china)(Received May 28, 20 Department science and technology Bank of Shanghai Shanghai 200010 P. R. China Information Engineering school University of Science and Technology Beijing 100083 P. R. China

Exceptional rules are often ignored because of their small support. However, they have high confidence, so they are useful sometimes. A new algorithm for mining exceptional rules is presented, which creates a large itemset from a relatively small database and scans the whole database only one time to generate all exceptional rules. This algorithm is proved to be quick and effective through its application in a mushroom database.

关键词： Exceptional rules Conventional rules Data mining.

The protection effect of β-CD on DNA damage induced by ultrafine TiO_2

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science china Chemistry 2007年第2期50卷 272-275页

作者： ZHU RongRong,WANG ShiLong,SUN XiaoYu,ZHANG Rui & YAO SiDe school of Life science and technology,Tongji university,shanghai 200092,china school of Life science and technology Tongji University Shanghai China

Under the photocatalysis of 365 nm ultraviolet radiation,ultrafine TiO2 caused the oxidative damage of Teasy plasmid DNA. The damage was determined by gel-electrophoresis. Then,a different dose of β-CD was added to the reaction,and the damage was restrained. The rate of damage restraining reached 97% when the mass of β-CD was 4 times as that of TiO2. Through UV scan and IR spectroscopy,it was found that the Ti-O of ultrafine TiO2 was bound with -OH of β-CD cavum and the -OH on the surface of ultrafine TiO2 disappeared,so the formation of ?OH was controlled. The ultrafine TiO2 has been widely used,but it was determined to be carcinogenic by some research. The protection effect of β-CD to DNA in the molecular level takes a new look on the surface modification of nano particles to decrease the toxic effect.

关键词： β-CD ultrafine TiO2 plasmid DNA oxide damage bond reaction damage restrain

Application of Fourier Slice Theorem in Wigner Operator Theory and New Complete Representation

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Communications in Theoretical Physics 2009年第11期52卷 829-831页

作者： WANG Tong-Tong~1 and FAN Hong-Yi~(2,3)1 school of Mathematics and Physics, Huangshi Institute of technology, Huangshi 435003, china2 Department of Material science and Engineering, university of science and technology of china, Hefei 230026, china3 Department of Physics, shanghai Jiao Tong university, shanghai 200030, china school of Mathematics and Physics Huangshi Institute of Technology Huangshi 435003 China Department of Material science and Engineering University of Science and Technology of China Hefei 230026 China Department of Physics Shanghai Jiao Tong University Shanghai 200030 China

By applying the Fourier slice theorem,S;（λ）=∫;P;（t）e;=F（λcosθ,λsinθ）,where P;（t）is aprojection of f（x,p）=（?）F（u,v）e;dudv along lines of constant,to the Wigner operator we are naturally led toa projection operator（pure state）,which results in a new complete *** Weyl orderimg formalism of theWigner operator is used in the derivation.

关键词： Wigner operator Fourier slice theorem new complete representation