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Chinese Journal of Lasers 2000年第3期9卷 35-41页

作者： J. Y. Chen-1 n. H. Cheung-2 S. C. Chen-2, M. C. Fung-3 W. n. Leung-4 n. K. Mak- 4+ ( -1department of Physics, Fudan university, Shanghai 200433, China -2department of Physics, Hong Kong Baptist university, Hong Kong, China -3department of Bi 复旦大学上海香港浸会大学香港香港大学香港

the intracellular localization of merocyanine 540 (MC540), a photosensitizer commonly used in the photo-inactivation of leukemia cells, was studied using confocal laser scanning microscopy. It was found for the first time that MC540 not only localized in the plasma membrane but also in the cytoplasm and the nuclear membrane of the murine myeloid leukemia M1 and WEHI 3B (JCS) cells. Exposure of MC540 treated leukemia cells to light under conditions that could cause photobleaching did not cause the redistribution of cell-bound MC540. Rapid localization of MC540 in the cytoplasm was observed 5 minutes after exposure of leukemia cell to MC540, indicating that MC540 could promptly be internalized by these two leukemia cell lines. In contrast, localization of MC540 was limited only to the plasma membrane of erythrocytes. these results suggest that the binding pattern of MC540 is cell type dependent and may be related to the efficacy of photosenitization in photodynamic therapy.

关键词： merocyanine 540 Confocal Laser Scanning Microscopy Myeloid Leukemia cell

Imprints of a gravitational wave through the weak field deflection of photons

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Chinese Physics C 2024年第8期48卷 240-245页

作者： Reggie C.Pantig Ali Övgün Physics department Mapúa University658 Muralla St.IntramurosManila 1002Philippines Physics department Eastern Mediterranean UniversityFamagusta99628 North Cyprusvia Mersin 10Turkiye

In this study,we investigate the novel phenomenon of gravitational lensing experienced by gravitational waves traveling past a Schwarzschild black hole perturbed by a specific,first-order,polar gravitational *** apply the Gauss-Bonnet theorem,finding a topological contribution to the deflection of light rays passing near the black *** demonstrate that the deflection angle can be determined by analyzing a region entirely outside the path of the light ray,leading to a calculation based solely on the parameters of the perturbing wave(Legendre polynomial order,l;frequency,σ).this approach offers a unique perspective on gravitational lensing and expands our understanding of black hole interactions with gravitational waves.

关键词： supermassive black holes gravitational waves chaos weak deflection angle Gauss-Bonnet theorem

A nano-plasmonic HMIM waveguide based concurrent dual-band BPF using circular ring resonator

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Optoelectronics Letters 2024年第3期20卷 152-156页

作者： Miriyala Sridhar Surendra Kumar Bitra tS n Murthy Koppireddi Padmaraju department of Electronics and Communication Engineering Koneru Lakshmaiah Education FoundationGunturIndia Astra Microwave Products Ltd. HyderabadIndia department of Electronics and Communication Engineering JNTU-GV College of EngineeringVizianagaramIndia department of Electronics and Communication Engineering Jawaharlal Nehru Technological University KakinadaKakinadaIndia

this article analyzes the transmission line characteristics of plasmonic hybrid metal insulator metal(HMIM) wave-guide, circular ring resonator(CRR) based dual-band band-pass filters with two transmission poles in both pass-bands in the optical regime using coupled line feed. the transmission line characteristics of an HMIM waveguide, such as characteristic impedance(Z_(PV)), effective refractive index(n_(eff)) and propagation length(L_(spp)), have been obtained by using full wave simulation.

关键词： waveguide resonator circular

nanomotion of bacteria to determine metabolic profile

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nanotechnology and Precision Engineering 2024年第1期7卷 1-9页

作者： S.n.Pleskova E.V.Lazarenko n.A.Bezrukov R.n.Kriukov A.V.Boryakov M.E.Dokukin S.I.Surodin Research Laboratory of Scanning Probe Microscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia department of nanotechnology and Biotechnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics and technology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to their visible motion such as swimming(e.g.,with the help ofﬂagella),bacteria can also exhibit nanomotion that is detectable only with highly sensitive instruments,and this study shows that it is possible to detect bacterial nanomotion using an AFM detection *** results show that the nanomotion characteristics depend on the bacterial strain,and that nanomotion can be used to sense the metabolic activity of bacteria because the oscillations are sensitive to the food preferences of the bacteria and the type of surrounding medium.

关键词： nanomotion Bacteria Cantilever Oscillation Atomic force microscopy Metabolism

Commentary on“Desialylated Platelets Maintain Immune Quiescence through Regulating Kupffer Cells”

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Research 2024年第3期6卷 621-623页

作者： Chen Li Craig n.Morrell Aab Cardiovascular Research Institute University of Rochester School of Medicine and DentistryRochesterNYUSA department of Pharmacology and Physiology University of Rochester School of Medicine and DentistryRochesterNYUSA department of Medicine University of Rochester School of Medicine and DentistryRochesterNYUSA department of Microbiology and Immunology University of Rochester School of Medicine and DentistryRochesterNYUSA department of Pathology and Laboratory Medicine University of Rochester School of Medicine and DentistryRochesterNYUSA.

Platelets have long been studied for their roles in hemostasis and vascular injury repair. However, there is a continually evolving and deepening understanding that platelets initiate and regulate responses to tissue injury and pathogens, leading to platelets now being considered immune modulatory cells [1]. Platelets actively participate in host immune responses directly through pathogen engulfing and killing, or by regulating both innate and adaptive immune responses to infection or tissue injury [2]. Activated platelets promote inflammatory responses to tissue injury or infection by direct contact dependent interactions with immune cells and through indirect interactions via released soluble factors. However, mice that are deficient in platelets have skewed t helper cell differentiation [3] and increased vascular permeability [4], implying poorly defined roles for platelets in maintaining healthy immune homeostasis.

关键词： Platelet homeostasis Immune

Implications of regional identity for neural stem and progenitor cell transplantation in the injured or diseased nervous system

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neural Regeneration Research 2024年第4期19卷 715-716页

作者： Prakruthi Amar Kumar Jennifer n.Dulin department of Biology Texas A&M UniversityCollege Station texas A&M Institute for neuroscience Texas A&M UniversityCollege Station

neural stem and progenitor cell(nSPC)transpla ntation has emerged as a promising therapeutic strategy for replacing lost neuronal populations and repairing damaged neural circuits following nervous system injury and disease.A great deal of experimental work has investigated the biology of nSPC grafting in preclinical animal models;more recently.

关键词： neural system injured

targeting muscle to treat Charcot-Marie-tooth disease

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neural Regeneration Research 2024年第8期19卷 1653-1654页

作者： David Villarroel-Campos James n.Sleigh department of neuromuscular Diseases and UCL Queen Square Motor neuron Disease Centre UCL Queen Square Institute of NeurologyUniversity College LondonLondonUK UK Dementia Research Institute University College LondonLondonUK

Charcot-Marie-tooth disease(CMt)is a hereditary peripheral neuropathy causing muscle weakness/wasting and sensory dysfunction predominantly in limb *** patients display gait abnormalities,foot deformities,loss of sens... 详细信息

关键词： Marie sensation neuropathy

Stochastic Ranking Improved teaching-Learning and Adaptive Grasshopper Optimization Algorithm-Based Clustering Scheme for Augmenting network Lifetime in WSns

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China Communications 2024年第9期21卷 159-178页

作者： n tamilarasan SB Lenin P Mukunthan nC Sendhilkumar department of Electronics and Communications Engineering Sri Indu College of Engineering and TechnologyHyderabadTelanganaIndia department of Electronics and Communications Engineering Sri Manakula Vinayagar Engineering CollegePondicherryIndia

In Wireless Sensor networks(WSns),Clustering process is widely utilized for increasing the lifespan with sustained energy stability during data *** clustering protocols were devised for extending network lifetime,but most of them failed in handling the problem of fixed clustering,static rounds,and inadequate Cluster Head(CH)selection criteria which consumes more *** this paper,Stochastic Ranking Improved teaching-Learning and Adaptive Grasshopper Optimization Algorithm(SRItL-AGOA)-based Clustering Scheme for energy stabilization and extending network *** SRItL-AGOA selected CH depending on the weightage of factors such as node mobility degree,neighbour's density distance to sink,single-hop or multihop communication and Residual Energy(RE)that directly influences the energy consumption of sensor *** specific,Grasshopper Optimization Algorithm(GOA)is improved through tangent-based nonlinear strategy for enhancing the ability of global *** the other hand,stochastic ranking and violation constraint handling strategies are embedded into teaching-Learning-based Optimization Algorithm(tLOA)for improving its exploitation ***,SR and VCH improved tLOA is embedded into the exploitation phase of AGOA for selecting better CH by maintaining better balance amid exploration and *** results confirmed that the proposed SRItL-AGOA improved throughput by 21.86%,network stability by 18.94%,load balancing by 16.14%with minimized energy depletion by19.21%,compared to the competitive CH selection approaches.

关键词： Adaptive Grasshopper Optimization Algorithm(AGOA) Cluster Head(CH) network lifetime teaching-Learning-based Optimization Algorithm(tLOA) Wireless Sensor networks(WSns)

Structural changes in the obese brain

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neural Regeneration Research 2024年第12期19卷 2561-2562页

作者： Anna R.R.Da Conceicao Marcelo n.n.Vieira Fernanda G.De Felice D’Or Institute for Research and Education Rio de JaneiroBrazil Institute of Medical Biochemistry Leopoldo De Meis Federal University of Rio de JaneiroRio de JaneiroBrazil Centre for neuroscience Studies Department of Biomedical and Molecular Sciences&Department of PsychiatryQueen’s UniversityKingstonONCanada

Obesity represents a major global health concern,with widespread growing prevalence and severe consequences for the quality of life and life expectancy of affected individuals and for the economic burden of healthcare systems(Prospective Studies Collaboration,2009).Obesity is a well-established risk factor for a variety of conditions including metabolic,vascula r,and heart diseases,and seve ral types of cancer(Prospective Studies Collaboration,2009).

关键词： diseases consequences prevalence

A Learning-based Control Framework for Fast and Accurate Manipulation of a Flexible Object

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Journal of Bionic Engineering 2024年第4期21卷 1761-1774页

作者： Junyi Wang Xiaofeng Xiong Silvia tolu Stanislav n.Gorb department of Electrical and Photonics Engineering Technical University of DenmarkAnker Engelunds Vej 101Kongens LyngbyZealand2800Denmark SDU Biorobotics Mærsk Mc-Kinney Møller InstituteUniversity of Southern Denmark(SDU)Campusvej 55Odense MFunen5230Denmark department Functional Morphology and Biomechanics Zoological InstituteUniversity of KielAm Botanischen Garten 1–9D-24118KielSchleswig-HolsteinGermany

this paper presents a learning-based control framework for fast(3 times of others).Besides,motion tracking errors are greatly reduced to 13.29 and 22.36 of constant impedance control by the OIAC of the proposed *** ad... 详细信息

this paper presents a learning-based control framework for fast(nd accurate manipulation of a flexible object,i.e.,whip *** framework consists of a motion planner learned or optimized by an algorithm,Online Impedance Adaptation Control(OIAC),a sim2real mechanism,and a visual feedback *** experimental results show that a soft actor-critic algorithm outperforms three Deep Reinforcement Learning(DRL),a nonlinear optimization,and a genetic algorithm in learning generalization of motion *** can greatly reduce average learning trials(to20 of others)and maximize average rewards(to>3 times of others).Besides,motion tracking errors are greatly reduced to 13.29 and 22.36 of constant impedance control by the OIAC of the proposed *** addition,the trajectory similarity between simulated and physical whips is *** presented framework provides a new method integrating data-driven and physics-based algorithms for controlling fast and accurate arm manipulation of a flexible object.

关键词： Deep reinforcement learning Deformable object manipulation Variable impedance control Sim2real Visual tracking