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Journal of huazhong university of science and technology(Medical sciences) 2001年第3期21卷 231-232页

作者：王欣邹声泉 department of surgery Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030

The role of CyclinD1 and estrogen receptor (ER) in the process of proliferation and metastasis of breast neoplasm and their relationship were studied. The expression levels of CyclinD1 and ER in the tissue samples were detected by using flow cytometry and L SAB immunohistochemistry staining, respectively. The results showed that CyclinD1 and ER expression levels in breast cancer were significantly higher than in benign breast neoplasm (P0.05), but the CyclinD1 expression level in ER (+) group was significantly higher than in ER (-) group (P<0.05). It was concluded that CyclinD1 expression level might be obviously related with the proliferation and metastasis of breast neoplasm and ER.

关键词： breast cancer CyclinD1 flow cytometry estrogen receptor

Optimality strategy of a sealed-offer simultaneous bargaining protocol

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science china(Information sciences) 2011年第1期54卷 79-90页

作者： ZHANG LinLan1,2.CHEN XueGuang2.& HONG Liu2.1School of Business,Hubei university,wuhan 430062.{2. 2.nstitute of Systems Engineering,huazhong university of science and technology,wuhan 430074,{2. 1. School of Business Hubei University Wuhan 430062 China2. Institute of Systems Engineering Huazhong University of Science and Technology Wuhan 430074 China

Alternating-offer bargaining protocol is the most predominant way for solving bilateral bargaining ***,alternating-offer may consume much time and cause a low effciency in some ***, a deadlock in which both negotiators are unwilling to concede or refuse to disclose more information may arise. Then mediation is *** paper presents an agent-based sealed-offer simultaneous bargaining protocol by introducing a nonbiased *** information of both agents is considered completely *** our agent-based model,both agents simultaneously submit their respective offers to the mediate *** offers of each agent are not revealed to the *** design can discourage counter-speculation and effectively control fraud and misrepresentation in a certain ***,we analyze how an agent can exploit the available information in selecting a strategy that maximizes its expected utility and give the optimal offers of each agent at each stage of the *** groups of automated experiments are conducted to evaluate the performance of the proposed automated negotiation procedure.

关键词： automated negotiation bargaining sealed-bid optimal strategy

A novel method to analyze damping effect of VSC based FACTS

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science china(Technological sciences) 2008年第12期51卷 2112-2119页

作者： DU WenJuan1,WANG HaiFeng2.& CHENG ShiJie3 1 Southeast university,Nanjing 2.0096,china 2.Queen’s university of Belfast,Belfast,BT9 5AH,UK 3 huazhong university of science and technology,wuhan 430074,china State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan University Chengdu 610065 China

A novel method to analyze the damping effect of the VSC based FACTS(VBF) device is proposed,which is developed on the basis of the well-known equalarea criterion and small-disturbance analysis of power system *** use of the proposed method,two conclusions are obtained for study of the damping effect of the *** research results clearly show the contribution of the VBF control to the damping of power system *** results of an example power system are used to verify the effectiveness of the proposed method.

关键词： power system low frequency oscillations FACTS equal-area criterion

LARGE DEFLECTION OF SUBMERGED PIPELINES LAID WITH AN ARTICULATED STINGER

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china Ocean Engineering 1988年第3期2卷 115-126页

作者： Huang Yuying and Zhu Dashan Professor, department of Mechanics, huazhong university of science and technology, {2. Lecturer, department of Mechanics, huazhong university of science and technology, {2. Dept. of Mechanics Huazhong Univ. of Sci. & Tech. Wuhan China

- An analytical method based on the Reference (Huang Yuying, 1986) is presented for finding the elastic deflection of pipelines laid with an articulated stinger. The suspended segment and the segment supported by the stinger are treated separately hnt simultaneously with the singular perturbation technique and by use of the continuous conditions at the joint between the two segments, an approximate solution of the second order to the deflection of the whole pipeline is obtained.

关键词： LARGE DEFLECTION OF SUBMERGED PIPELINES LAID WITH AN ARTICULATED STINGER

Spiral waves in CIMA model and its LBGK simulation

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Communications in Nonlinear science and Numerical Simulation 2001年第2期6卷 68-73页

作者： Qing LI, Chuguang ZHENG and Nengchao WANG College of Computer science and technology, {2., wuhan 430074, china e-mail: qingli @ public. *** State Key Laboratory of Coal Combustion, huazhong university College of Computer science and technology Huazhong University of Science and Technology Wuhan 430074 China State Key Laboratory of Coal Combustion Huazhong University of Science and Technology Wuhan 430074 China Parallel Computation Institute Huazhong University of Science and Technology Wuhan 430074 China

Two type of structures-Turing patterns and spiral waves-are obtained in chloride-iodide-malonic acid (CIMA) reaction-diffusion model by using lattice Bhatnagar-Gross-Krook (LBGK) method.

关键词： lattice Boltzmann method reaction-diffusion Turing patterns spiral waves

APPLICATIONS OF INTEGRATED SEMIGROUPS TO HIGHER ORDER ABSTRACT CAUCHY PROBLEMS

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Systems science and Mathematical sciences 1992年第4期5卷 316-327页

作者： ZHENG Quan (department of Mathematics,huazhong university of science and technology,{2. 430074,china)

This paper is concerned with applications of integrated semigroups tothe following Cauchy problem:（ACPn） xn（t）=sum from i=0 to n-1 Bixi（t）,xi（0）=xi,0（?）i（?）n-1where Bi （0（?）i（?）n-1） are closed linear operators on a Banach space *** theorem,a condition of the solvability,a condition of the exponentialwell-posedness,and some results for the special case that Bn-1 is bounded andD(Bn-2./sub>)（?）D（Bi）（0（?）i（?）n-3） are obtained.

关键词： Higher order abstract Cauchy problem uniqueness solvability exponential well-posedness integrated semigroup

Effect of Inhalational Anesthetics on Cytotoxicity and Intracellular Calcium Differently in Rat Pheochromocytoma Cells (PC12.

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Journal of huazhong university of science and technology(Medical sciences) 2008年第1期28卷 104-109页

作者：王秋筠李克忠姚尚龙 department of Anesthesiology Union Hospital Tongji Medical College Huazhong University of Science and Technology

Isoflurane, a commonly used inhaled anesthetic, induces apoptosis in rat pheochromocytoma cells （PC12. in a concentration- and time-dependent manner with unknown mechanism. We hypothesized that isoflurane induced apoptosis by causing abnormal calcium release from the endoplasmic reticulum （ER） via activation of inositol 1,4,5-trisphosphate （IP3） receptors. Alzheimer＇s presenilin-1 （PS 1） mutation increased activity of IP3 receptors and therefore rendered cells vulnerable to isoflurane-induced cytotoxicity. Sevoflurane and desflurane had less ability to disrupt intracellular calcium homeostasis and thus being less potent pared the cytotoxic effects of various inhaled to cause cytotoxicity. This study examined and com-anesthetics on PC12.cells transfected with the Alzheimer＇s mutated PS 1 （L2.6V） and the disruption of intracellular calcium homeostasis. PC 12.cells transfected with wild type （WT） and mutated PS 1 （L2.6V） were treated with equivalent of 1 MAC of isoflurane, sevoflurane and desflurane for 12.h. MTT reduction and LDH release assays were performed to evaluate cell viability. Changes of calcium concentration in cytosolic space （[Ca^2.]c） were determined after exposing different types of cells to various inhalational anesthetics. The effects of IP3 receptor antagonist xestospongin C on isoflurane-induced cytotoxicity and calcium release from the ER in L2.6V PC12.cells were also determined. The results showed that isoflurane at 1 MAC for 12.h induced cytoxicity in L2.6V but not WT PC12.cells, which was also associated with greater and faster elevation of peak [Ca^2.]c in L2.6V than in the WT cells. Xestospongin C significantly ameliorated isoflurane cytotoxicity in L2.6V cells, as well as inhibited the calcium release from the ER in L2.6V cells. Sevoflurane and desflurane at equivalent exposure to isoflurane did not induce similar cytotoxicity or elevation of peak [Ca^2.]c in L2.6V PC 12.cells. These results suggested that isoflurane induced cytoxicity by par

关键词： inhalational anesthetics cytotoxicity calcium

Removal of elemental mercury by iodine-modified rice husk ash sorbents

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Journal of Environmental sciences 2010年第10期22卷 1629-1636页

作者： Pengfei Zhao,Xin Guoff,Chuguang Zheng State Key Laboratory of Coal Combustion,huazhong university of science and technology,wuhan 430074,{2. [a] State Key Laboratory of Coal Combustion Huazhong University of Science technology Wuhan 430074 China

Iodine-modified calcium-based rice husk ash sorbents （I2.CaO/RHA） were synthesized and characterized by X-ray diffraction, X-ray fluorescence, and N2.isotherm adsorption/desorption. Adsorption experiments of vapor-phase elemental mercury （Hg^0） were performed in a laboratory-scale fixed-bed reactor. I2.CaO/RHA performances on Hg^0 adsorption were compared with those of modified Cabased fly ash sorbents （I2.CaO/FA） and modified fly ash sorbents （I2.FA）. Effects of oxidant loading, supports, pore size distribution, iodine impregnation modes, and temperature were investigated as well to understand the mechanism in capturing Hg^0. The modified sorbents exhibited reasonable efficiency for Hg^0 removal under simulated flue gas. The surface area, pore size distribution, and iodine impregnation modes of the sorbents did not produce a strong effect on Hg^0 capture efficiency, while fair correlation was observed between Hg^0 uptake capacity and iodine concentration. Therefore, the content of 12.impregnated on the sorbents was identified as the most important factor influencing the capacity of these sorbents for Hg^0 uptake. Increasing temperature in the range of 80-140℃ caused a rise in Hg^0 removal. A reaction mechanism that may explain the experimental results was presumed based on the characterizations and adsorption study.

关键词： mercury sorbents fly ash rice husk ash iodine impregnation

Ti(C, N) BASED CERAMETS AND ITS FRACTAL ANALYSIS OF FRACTURE SURFACES

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中国有色金属学会会刊：英文版 1996年第2期6卷 101-104页

作者： Liu Ning(department of Materials science and Engineering,Anhui institute of {2., Hefei 2.0069)Hu Zhenhua Cui Kun(huazhong university of science and technology, wuhan 430074) ANHUI INST TECHNOL DEPT MAT SCI & ENGNHEFEI 230069PEOPLES R CHINA huazhong UNIV SCI & TECHNOL WUHAN 430074PEOPLES R CHINA

Ｔｉ（Ｃ，Ｎ）ＢＡＳＥＤＣＥＲＡＭＥＴＳＡＮＤＩＴＳＦＲＡＣＴＡＬＡＮＡＬＹＳＩＳＯＦＦＲＡＣＴＵＲＥＳＵＲＦＡＣＥＳＬｉｕＮｉｎｇ（ＤｅｐａｒｔｍｅｎｔｏｆＭａｔｅｒｉａｌｓＳｃｉｅｎｃｅａｎｄＥｎｇｉｎｅｅｒｉｎ... 详细信息

Ｔｉ（Ｃ，Ｎ）ＢＡＳＥＤＣＥＲＡＭＥＴＳＡＮＤＩＴＳＦＲＡＣＴＡＬＡＮＡＬＹＳＩＳＯＦＦＲＡＣＴＵＲＥＳＵＲＦＡＣＥＳＬｉｕＮｉｎｇ（ＤｅｐａｒｔｍｅｎｔｏｆＭａｔｅｒｉａｌｓＳｃｉｅｎｃｅａｎｄＥｎｇｉｎｅｅｒｉｎｇ，Ａｎｈｕｉｉｎｓｔｉｔｕｔｅｏ...

关键词： Ti(C, N) based ceramets fracture surface fractal analysis

Experimental Study on Semiconductor Optical Amplifiers with Angled Facets

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Chinese Journal of Lasers 1999年第1期8卷 8-11页

作者： DUAN Zigang HUANG Dexiu LIU Deming ZHANG Zemin (department of Opto electronics Engineering, huazhong university of science and technology, {2. 430074, china) 华中理工大学光电工程系湖北武汉 430074 华中理工大学光电工程系湖北武汉

１ＩｎｔｒｏｄｕｃｔｉｏｎＳＯＡｗｉｌｂｅｏｎｅｏｆｔｈｅｋｅｙｃｏｍｐｏｎｅｎｔｓｉｎｔｈｅａｌｏｐｔｉｃａｌｎｅｔｗｏｒｋｉｎｔｈｅｆｕｔｕｒｅ．ＳＯＡｈａｓｍａｎｙｖｅｒｙｉｍｐｏｒｔａｎｔａｐｐｌｉｃａｔｉ... 详细信息

１ＩｎｔｒｏｄｕｃｔｉｏｎＳＯＡｗｉｌｂｅｏｎｅｏｆｔｈｅｋｅｙｃｏｍｐｏｎｅｎｔｓｉｎｔｈｅａｌｏｐｔｉｃａｌｎｅｔｗｏｒｋｉｎｔｈｅｆｕｔｕｒｅ．ＳＯＡｈａｓｍａｎｙｖｅｒｙｉｍｐｏｒｔａｎｔａｐｐｌｉｃａｔｉｏｎｓ，ｓｕｃｈａｓｗａｖｅｌｅｎ...

关键词： tilted cavity antireflective coating gain semiconductor optical amplifier