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小型化光纤陀螺的轴向磁场误差特性建模方法探讨

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中国惯性技术学报 2012年第1期20卷 84-89页

作者：王立辉徐晓苏刘锡祥蔡毓峰东南大学仪器科学与工程学院微惯性仪表与先进导航技术教育部重点实验室南京210096 国科学院西安光学精密机械研究所瞬态光学与光子技术国家重点实验室西安710119 天津航海仪器研究所天津300131

小型化光纤陀螺的主要特点是光纤环径向尺寸逐步缩小,而轴向尺寸逐步增大,由此导致轴向磁场误差成为影响小型化光纤陀螺精度的重要因素之一。以小型化光纤陀螺轴向磁场误差特性为研究对象,依据光纤环中光纤的四极对称排列结构,提出轴向... 详细信息

小型化光纤陀螺的主要特点是光纤环径向尺寸逐步缩小,而轴向尺寸逐步增大,由此导致轴向磁场误差成为影响小型化光纤陀螺精度的重要因素之一。以小型化光纤陀螺轴向磁场误差特性为研究对象,依据光纤环中光纤的四极对称排列结构,提出轴向螺旋角展开分析法,利用Jones矩阵分别构建保偏型光纤陀螺及消偏型光纤陀螺的传输矩阵及轴向磁场误差模型,探讨光纤扭曲应力寄生圆双折射、轴向尺寸等因素与非互易性Faraday磁场相位误差的关系,得出光纤陀螺轴向磁场漂移误差的数学描述,以此为理论依据,探讨小型化光纤陀螺的轴向磁场误差因素,并提出相应的措施。

关键词：小型化光纤陀螺磁场误差非互易相位误差漂移

基于细菌视紫红质薄膜的空间光调制器实验研究

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物理学报 2003年第3期52卷 761-766页

作者：杨文正杨青陈烽冯晓强侯洵中国科学院西安光学精密机械研究所瞬态光学技术国家重点实验室西安710068 西安交通大学电子科学与技术系西安710049

阐述了利用细菌视紫红质薄膜 (BR薄膜 )优良的非线性光学特性作为光寻址的空间光调制器的实验研究 .BR有两个重要的光敏中间态 (B态和M态 ) ,其吸收带 (B态吸收峰为 5 70nm ,M态吸收峰为 4 12.m)重叠区域较少 ,利用其正向 (B→M)和逆向... 详细信息

阐述了利用细菌视紫红质薄膜 (BR薄膜 )优良的非线性光学特性作为光寻址的空间光调制器的实验研究 .BR有两个重要的光敏中间态 (B态和M态 ) ,其吸收带 (B态吸收峰为 5 70nm ,M态吸收峰为 4 12.m)重叠区域较少 ,利用其正向 (B→M)和逆向 (M→B)光反应之间转化关系和B态与M态的差异吸收实现了相干光学图像到非相干光学图像的转换实验 .采用经基因改性的细菌视紫红质薄膜 (BRD96N)材料 ,使用 6 70nm相干光作为写入光 ,5 30nm非相干光作为读出光 ,得到了分辨率约为 2.0 0lines mm ,对比度约为 2..1∶1的实验结果 .

关键词：实验研究光寻址空间光调制器细菌视紫红质薄膜 BR薄膜非线性光学特性相干光非相干光图像相互转换光学图像光学信息处理

Birefrmgent laterally Sheared Beam Splitter - Savart polariscope

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Birefrmgent laterally Sheared Beam Splitter - Savart polaris...

All-Optical Bypass-Exchange Switches

2.d International Symposium on Advanced Optical Manufacturing and Testing Technologies

作者： Chunmin Zhang Baochang Zhao Bin xiangli Yingcai Li Zhihong Peng Shool of Science xi’an Jiaotong University xi’an 710049 People’s Republic of china xi’an Institute of optics and precision mechanics chinese academy of sciences xi’an 710068 People’s Republic of china

＜正＞A laterally sheared beam splitter-savart polariscope was developed based on a single birefringent component. It is a key part in a novel polarization interference imaging spectrometer. The Savart polariscope consists of two paralled plales of calcite cut at an arbitrary angle to the optics axis and can split up a ray of light incident on the surface into an ordinary ray and an extraordinary ray. The output rays are paralled laterally sheared. The Savart polariscope is 2.×2.×12.m3 in size. The lateral displacement is 1mm and transmissivity is about 90 percent in spectral range of 0.4-2.5μm A static polarization imaging spectrometer based on a Savart polariscope has advantage of ultra-compact size, wide field of view, high throughput and without any moving parts. The principle and construction of Savart polariscope arc described, and the experimental results of the interference imaging spectrum are given.

关键词： Birefringent crystal Savart polariscope Polarization interference imaging spectrometer

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chinese Journal of Lasers 1998年第2期 37-46页

作者： YUN Zhisheng LI Yulin LIU JifangXU Xuemei +) LIU Muxing+)(xian Institute of {2. & precision mechanics, chinese academy of sciences,P.O.Box 80(2.), xian 710068, china +)Dept. of Instrumental Engineering, xian Institu

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Ａｌ┐ＯｐｔｉｃａｌＢｙｐａｓ┐ＥｘｃｈａｎｇｅＳｗｉｔｃｈｅｓＹＵＮＺｈｉｓｈｅｎｇＬＩＹｕｌｉｎＬＩＵＪｉｆａｎｇＸＵＸｕｅｍｅｉ＋）ＬＩＵＭｕｘｉｎｇ＋）（ＸｉａｎＩｎｓｔｉｔｕｔｅｏｆＯｐｔｉｃｓ＆ＰｒｅｃｉｓｉｏｎＭｅｃｈａｎｉｃｓ，Ｃ...

关键词： optical bypassexchange switch electricoptic effect phase modulation

Immune-tumor interaction dictates spatially directed evolution of esophageal squamous cell carcinoma

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National Science Review 2024年第5期11卷 170-185页

作者： Yong Zhou Shanlan Mo Heyang Cui Ruifang Sun Weimin Zhang xiaofei Zhuang Enwei Xu Hongyi Li Yikun Cheng Yongsheng Meng Meilin Liu Ting Yan Huijuan Liu Ling Zhang Bin Yang Yanfeng xi Shubin Wang xiaolong Cheng Shuai Cheng Li Zhihua Liu Qimin Zhan Zheng Hu Yongping Cui Cancer Institute Department of Pathology Peking University Shenzhen Hospital Shenzhen Peking University-the Hong Kong University of Science and Technology(PKU-HKUST) Medical Center Institute of Cancer ResearchShenzhen Bay Laboratory Key Laboratory of Cellular Physiology of the Ministry of Education Department of Pathology Shanxi Medical University City University of Hong Kong Shenzhen Research Institute CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic BiologyShenzhen Institute of Advanced TechnologyChinese Academy of Sciences Department of Surgery Faculty of Medicine The Chinese University of Hong Kong Department of Tumor Biobank Shanxi Province Cancer HospitalShanxi Hospital Affiliated to Cancer HospitalChinese Academy of Medical SciencesCancer Hospital Affiliated to Shanxi Medical University Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Laboratory of Molecular Oncology Peking University Cancer Hospital & Institute Research Unit of Molecular Cancer Research Chinese Academy of Medical Sciences Department of Thoracic Surgery Shanxi Province Cancer HospitalShanxi Hospital Affiliated to Cancer HospitalChinese Academy of Medical SciencesCancer Hospital Affiliated to Shanxi Medical University Department of Pathology Shanxi Province Cancer HospitalShanxi Hospital Affiliated to Cancer HospitalChinese Academy of Medical SciencesCancer Hospital Affiliated to Shanxi Medical University College of Letters & Science University of California Berkeley State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

Esophageal squamous cell carcinoma（ESCC） is a poor-prognostic cancer type with extensive intra-and inter-patient heterogeneity in both genomic variations and tumor microenvironment（TME）. However, the patterns and drivers of spatial genomic and microenvironmental heterogeneity of ESCC remain largely unknown. Here, we generated a spatial multi-omic atlas by whole-exome, transcriptome, and methylome sequencing of 507 tumor samples from 103 patients. We identified a novel tumor suppressor PREX2.accounting for 2.% of ESCCs with frequent somatic mutations or hyper-methylation, which promoted migration and invasion of ESCC cells in vitro. Analysis of the TME and quantification of subclonal expansion indicated that ESCCs undergo spatially directed evolution, where subclones mostly originated from the tumor center but had a biased clonal expansion to the upper direction of the ***, we found upper regions of ESCCs often underwent stronger immunoediting with increased selective fitness, suggesting more stringent immune selection. In addition, distinct TMEs were associated with variable genomic and clinical outcomes. Among them, hot TME was associated with high immune evasion and subclonal heterogeneity. We also found that immunoediting, instead of CD8+T cell abundance, acts as an independent prognostic factor of ESCCs. Importantly, we found significant heterogeneity in previously considered potential therapeutic targets, as well as BRCAness characteristics in a subset of patients, emphasizing the importance of focusing on heterogeneity in ESCC targeted ***, these findings provide novel insights into the mechanisms of the spatial evolution of ESCC and inform precision therapeutic strategies.

关键词： squamous cell carcinoma heterogeneity multi-omics evolution tumor microenvironment

Computer Controlled Polishing of the Off-axis Aspheric Mirrors

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光学精密工程 2001年第5期9卷 467-473页

作者： ZHANG Xue jun,WENG Zhi cheng,ZHANG Zhong yu, WANG Quan dou,ZHANG Feng (Changchun Institute of optics, Fine mechanics and Physics,{2., Changchun 13002., china) 中科院长春光学精密机械与物理所吉林长春 1 30 0 2 2

In this paper, the manufacturing and testing procedures to make large off-axis aspherical mirrors are presented. The difficulties in polishing and testing for both circular aperture and rectangular aperture mirrors are previewed, and a possible solution is given. The two mirrors have been polished by means of CCOS, and the final accuracy is 2.nm rms for 770mm×2.0mm rectangular mirror and 2.nm rms for φ600mm circular mirror. These results just meet the optical tolerances specified by the designer, and the manufacturing and testing procedures presented here show good ability to make the large off-axis aspherical mirrors.

关键词： asphere computer-controlled polishing optical testing

Maximum Likelihood Estimation of the Identification Parameters and Its Correction

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Journal of Systems Engineering and Electronics 2002年第4期13卷 31-38页

作者： An Kai, Ma Jiaguang & Fu Chengyu Institute of optics and Electronics, chinese academy of sciences, Chengdu 610041, P. R.{2. Institute of optics and Electronics Chinese Academy of Sciences Chengdu 610041 P. R. China

By taking the subsequence out of the input-output sequence of a system polluted by white noise, an independent observation sequence and its probability density are obtained and then a maximum likelihood estimation of the identification parameters is given. In order to decrease the asymptotic error, a corrector of maximum likelihood (CML) estimation with its recursive algorithm is given. It has been proved that the corrector has smaller asymptotic error than the least square methods. A simulation example shows that the corrector of maximum likelihood estimation is of higher approximating precision to the true parameters than the least square methods.

关键词： Probability density Noise Least square methods Corrector of maximum likelihood estimation.

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细菌视紫红质对调制光的响应特性

生物化学与生物物理进展 1997年第5期24卷 427-430页

作者：姚保利徐大纶侯洵胡坤生王敖金中国科学院西安光学精密机械研究所瞬态光学技术国家重点实验室西安710068 中国科学院生物物理研究所北京100101

细菌视紫红质在结构上与视紫红质的相似性使其具有某些视觉响应特性 .用电泳法在不锈钢电极上沉积出定向紫膜薄膜 ,构成不锈钢 /紫膜 /凝胶 /铜电极结构的光接收器 .在调制光作用下 ,光接收器显示出对光强变化的微分响应特性 .测量了光... 详细信息

细菌视紫红质在结构上与视紫红质的相似性使其具有某些视觉响应特性 .用电泳法在不锈钢电极上沉积出定向紫膜薄膜 ,构成不锈钢 /紫膜 /凝胶 /铜电极结构的光接收器 .在调制光作用下 ,光接收器显示出对光强变化的微分响应特性 .测量了光电压随调制频率和入射光功率的变化关系 .比较和讨论了细菌视紫红质对调制光响应特性与视觉频闪及明暗感的相关性 .

关键词：细菌视紫红质紫膜生物膜调制光

Algorithm of Reducing the Non-uniformity of Images in LED Display Panel

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Algorithm of Reducing the Non-uniformity of Images in LED Di...